My microbial galaxy tattoo with all the microbes I've worked with so far ✨🦠 Except the Pseudomonas aeruginosa is commonly mistaken for a sperm cell 🥹
November 17, 2024 at 5:06 PM
My microbial galaxy tattoo with all the microbes I've worked with so far ✨🦠 Except the Pseudomonas aeruginosa is commonly mistaken for a sperm cell 🥹
Our first lab group Christmas dinner 🤩 featuring awesome and very cute crochet Pseudomonas made by PhD student Lauren! 🦠 🦠
December 19, 2024 at 5:58 AM
Our first lab group Christmas dinner 🤩 featuring awesome and very cute crochet Pseudomonas made by PhD student Lauren! 🦠 🦠
Some beautifully blue Pseudomonas on its way to be sequenced at microbesNG! 🦠🧬✉️
February 23, 2024 at 4:00 PM
Some beautifully blue Pseudomonas on its way to be sequenced at microbesNG! 🦠🧬✉️
Published on my birthday 🎉
Another paper in collaboration with @themaxwelllab.bsky.social
Phage reprogramming of Pseudomonas aeruginosa amino acid metabolism drives efficient phage replication
doi.org/10.1128/mbio...
🦠🧫🧪🧬
Another paper in collaboration with @themaxwelllab.bsky.social
Phage reprogramming of Pseudomonas aeruginosa amino acid metabolism drives efficient phage replication
doi.org/10.1128/mbio...
🦠🧫🧪🧬
February 7, 2025 at 3:38 PM
Published on my birthday 🎉
Another paper in collaboration with @themaxwelllab.bsky.social
Phage reprogramming of Pseudomonas aeruginosa amino acid metabolism drives efficient phage replication
doi.org/10.1128/mbio...
🦠🧫🧪🧬
Another paper in collaboration with @themaxwelllab.bsky.social
Phage reprogramming of Pseudomonas aeruginosa amino acid metabolism drives efficient phage replication
doi.org/10.1128/mbio...
🦠🧫🧪🧬
Very happy to share the final version of our work on the evolution of broad host virulence in Pseudomonas out now @cellhostmicrobe It’s just in time for the holidays 🎄🦠 www.cell.com/cell-host-mi...
A necrotizing toxin enables Pseudomonas syringae infection across evolutionarily divergent plants
Grenz et al. interrogate the Pseudomonas syringae species complex for its capacity to infect evolutionarily divergent host plants. Their results demonstrate that broad host isolates from phylogroup 2 rely on the lipopeptide toxin syringomycin to promote host necrosis and enhance bacterial growth in plants.
www.cell.com
December 19, 2024 at 4:10 PM
Very happy to share the final version of our work on the evolution of broad host virulence in Pseudomonas out now @cellhostmicrobe It’s just in time for the holidays 🎄🦠 www.cell.com/cell-host-mi...
𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 🦠 ist einer der häufigsten “Krankenhauskeime”. Nun wurde ein klinisches Isolat identifiziert, das medizinisch relevanten Kunststoff abbauen kann, was auch die Biofilmbildung fördert. #MibiFacts 🧵1/4
Pseudomonas aeruginosa clinical isolates can encode plastic-degrading enzymes that allow survival on plastic and augment biofilm formation
Howard et al. demonstrate that clinical isolates of the opportunistic pathogen Pseudomonas
aeruginosa can encode functional plastic-degrading enzymes and that these enzymes
can influence bacterial bio...
www.cell.com
May 14, 2025 at 5:54 PM
𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 🦠 ist einer der häufigsten “Krankenhauskeime”. Nun wurde ein klinisches Isolat identifiziert, das medizinisch relevanten Kunststoff abbauen kann, was auch die Biofilmbildung fördert. #MibiFacts 🧵1/4
Did you know that the presence of #Pseudomonas spp. in the water bodies where #Anopheles mosquitoes grow can increase their resistance to #insecticide? 🦟 🦠 Curious? Check our paper below! :)
rdcu.be/d1UmA
#MicroSky #SymbioSky #EvoSky
rdcu.be/d1UmA
#MicroSky #SymbioSky #EvoSky
Exposure to Pseudomonas spp. increases Anopheles gambiae insecticide resistance in a host-dependent manner
Scientific Reports - Exposure to Pseudomonas spp. increases Anopheles gambiae insecticide resistance in a host-dependent manner
rdcu.be
November 30, 2024 at 7:28 AM
Did you know that the presence of #Pseudomonas spp. in the water bodies where #Anopheles mosquitoes grow can increase their resistance to #insecticide? 🦟 🦠 Curious? Check our paper below! :)
rdcu.be/d1UmA
#MicroSky #SymbioSky #EvoSky
rdcu.be/d1UmA
#MicroSky #SymbioSky #EvoSky
🦠 New preprint 🦠
Really happy to see this up on bioRxiv - my 1st as senior author & Lina’s 1st as first author 🎉 a double whammy.
📄 Antibiotic resistance alters the ability of Pseudomonas aeruginosa to invade the respiratory microbiome
(1/n)
www.biorxiv.org/content/10.1...
Really happy to see this up on bioRxiv - my 1st as senior author & Lina’s 1st as first author 🎉 a double whammy.
📄 Antibiotic resistance alters the ability of Pseudomonas aeruginosa to invade the respiratory microbiome
(1/n)
www.biorxiv.org/content/10.1...
Antibiotic resistance alters the ability of Pseudomonas aeruginosa to invade the respiratory microbi...
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
November 16, 2023 at 8:26 AM
🦠 New preprint 🦠
Really happy to see this up on bioRxiv - my 1st as senior author & Lina’s 1st as first author 🎉 a double whammy.
📄 Antibiotic resistance alters the ability of Pseudomonas aeruginosa to invade the respiratory microbiome
(1/n)
www.biorxiv.org/content/10.1...
Really happy to see this up on bioRxiv - my 1st as senior author & Lina’s 1st as first author 🎉 a double whammy.
📄 Antibiotic resistance alters the ability of Pseudomonas aeruginosa to invade the respiratory microbiome
(1/n)
www.biorxiv.org/content/10.1...
So eine schöne Liste von verschiedenen Bakterien. Wo man die gefunden hat? In Nespresso Maschinen. What else 😁🦠☕️
📄 www.nature.com/articles/sre...
📄 www.nature.com/articles/sre...
February 5, 2026 at 6:32 PM
So eine schöne Liste von verschiedenen Bakterien. Wo man die gefunden hat? In Nespresso Maschinen. What else 😁🦠☕️
📄 www.nature.com/articles/sre...
📄 www.nature.com/articles/sre...
Pseudomonas can be so cool and slimy! 🦠 🔬 doi.org/10.1128/jb.0...
In vivo and in vitro analyses of the role of the Prc protease in inducing mucoidy in Pseudomonas aeruginosa | Journal of Bacteriology
After colonizing the lungs of individuals with cystic fibrosis, Pseudomonas aeruginosa undergoes mutagenic conversion to a mucoid form, worsening the prognosis. Most mucoid
isolates have a truncated n...
doi.org
November 14, 2024 at 4:18 AM
Pseudomonas can be so cool and slimy! 🦠 🔬 doi.org/10.1128/jb.0...
Sharing the preprint for my first foray into experimental evolution: adaptation of Pseudomonas aeruginosa to repeated invasion into a commensal competitor 🦠🧬
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Adaptation of Pseudomonas aeruginosa to repeated invasion into a commensal competitor
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
March 20, 2024 at 8:13 AM
Sharing the preprint for my first foray into experimental evolution: adaptation of Pseudomonas aeruginosa to repeated invasion into a commensal competitor 🦠🧬
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
We are excited to share our new preprint, “Canonical pathoadaptive cystic fibrosis genes in Pseudomonas aeruginosa are not CF-specific”! 🦠
Great project with @emehlferber.bsky.social and @brownlab.bsky.social
www.biorxiv.org/content/10.6...
Thread below 🧵
Great project with @emehlferber.bsky.social and @brownlab.bsky.social
www.biorxiv.org/content/10.6...
Thread below 🧵
Canonical pathoadaptive cystic fibrosis genes in Pseudomonas aeruginosa are not CF-specific
Research on Pseudomonas aeruginosa adaptation in cystic fibrosis (CF) has historically relied on comparing chronic isolates to laboratory reference strains, or evolving reference strains in environmen...
www.biorxiv.org
August 21, 2026 at 3:31 PM
We are excited to share our new preprint, “Canonical pathoadaptive cystic fibrosis genes in Pseudomonas aeruginosa are not CF-specific”! 🦠
Great project with @emehlferber.bsky.social and @brownlab.bsky.social
www.biorxiv.org/content/10.6...
Thread below 🧵
Great project with @emehlferber.bsky.social and @brownlab.bsky.social
www.biorxiv.org/content/10.6...
Thread below 🧵
3/11 🦠 What's living on wild plants? A LOT. Non-plant DNA sequencing reads ranged from <5% to 75%. Pseudomonas, Sphingomonas, Hyaloperonospora, Albugo — all present, all variable.
March 14, 2026 at 9:41 AM
3/11 🦠 What's living on wild plants? A LOT. Non-plant DNA sequencing reads ranged from <5% to 75%. Pseudomonas, Sphingomonas, Hyaloperonospora, Albugo — all present, all variable.
Who couldn’t use a little OUTSIDE ASSISTANCE 🦠 ???
Intracellular 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 cells can only escape vacuoles with help from extracellular cells via type III secretion–driven Ca²⁺ influx, ultimately promoting pathogen spread in vivo.
Suzanne Fleiszig Lab @UCBerkeley in Nature Comm
Intracellular 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 cells can only escape vacuoles with help from extracellular cells via type III secretion–driven Ca²⁺ influx, ultimately promoting pathogen spread in vivo.
Suzanne Fleiszig Lab @UCBerkeley in Nature Comm
August 12, 2025 at 11:28 AM
Who couldn’t use a little OUTSIDE ASSISTANCE 🦠 ???
Intracellular 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 cells can only escape vacuoles with help from extracellular cells via type III secretion–driven Ca²⁺ influx, ultimately promoting pathogen spread in vivo.
Suzanne Fleiszig Lab @UCBerkeley in Nature Comm
Intracellular 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 cells can only escape vacuoles with help from extracellular cells via type III secretion–driven Ca²⁺ influx, ultimately promoting pathogen spread in vivo.
Suzanne Fleiszig Lab @UCBerkeley in Nature Comm
🆕📃: #Pseudomonas🦠 helps #plants🌾 grow better under #Nitrogen limitation by stimulating mild protein changes, in the #root, only @⬇️#N.
#phenomics #PlantSci #Botany #proteomics #lipidomics #phenotyping #PlantMicrobeInteractions #PMI 🧪 #Brachypodium #PlantCellEnvir #PCE
doi.org/10.1111/pce....
#phenomics #PlantSci #Botany #proteomics #lipidomics #phenotyping #PlantMicrobeInteractions #PMI 🧪 #Brachypodium #PlantCellEnvir #PCE
doi.org/10.1111/pce....
Systems‐Level Plant Responses Reveal Pseudomonas‐Mediated Growth Promotion in Brachypodium Under Nitrogen Limitation
The plant growth–promoting bacterium Pseudomonas koreensis improves Brachypodium distachyon growth under limited nitrogen by modulating plant-encoded N acquisition and metabolic organization within a....
doi.org
May 27, 2026 at 1:25 PM
🆕📃: #Pseudomonas🦠 helps #plants🌾 grow better under #Nitrogen limitation by stimulating mild protein changes, in the #root, only @⬇️#N.
#phenomics #PlantSci #Botany #proteomics #lipidomics #phenotyping #PlantMicrobeInteractions #PMI 🧪 #Brachypodium #PlantCellEnvir #PCE
doi.org/10.1111/pce....
#phenomics #PlantSci #Botany #proteomics #lipidomics #phenotyping #PlantMicrobeInteractions #PMI 🧪 #Brachypodium #PlantCellEnvir #PCE
doi.org/10.1111/pce....
A rescue puppy is to become one of only a handful of dogs in the world able to detect a multi-drug resistant lung infection.
Chilli is being trained to identify the scent of pseudomonas aeruginosa, a major cause of lung damage in cystic fibrosis.
🧪🐕🦠
@medsky.social
www.bbc.co.uk/news/article...
Chilli is being trained to identify the scent of pseudomonas aeruginosa, a major cause of lung damage in cystic fibrosis.
🧪🐕🦠
@medsky.social
www.bbc.co.uk/news/article...
Battersea rescue dog trained to detect lung infection
Chilli will be able to identify the scent of pseudomonas aeruginosa in people with cystic fibrosis.
www.bbc.co.uk
January 28, 2026 at 6:43 AM
A rescue puppy is to become one of only a handful of dogs in the world able to detect a multi-drug resistant lung infection.
Chilli is being trained to identify the scent of pseudomonas aeruginosa, a major cause of lung damage in cystic fibrosis.
🧪🐕🦠
@medsky.social
www.bbc.co.uk/news/article...
Chilli is being trained to identify the scent of pseudomonas aeruginosa, a major cause of lung damage in cystic fibrosis.
🧪🐕🦠
@medsky.social
www.bbc.co.uk/news/article...
Happy new year! The second big project of my PhD in Rachel Whitaker's lab is now up! 🎉 We look at how provirus infection affects the evolution of the bacterial chromosome with different types of viral induction – with CRISPRs or antibiotics. Take a peek 🦠 www.biorxiv.org/content/10.6...
Provirus induction diversifies adaptive variation in Pseudomonas aeruginosa lysogen populations
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that forms chronic infections in people with cystic fibrosis. Often P. aeruginosa strains are lysogens, infected with proviruses, that ...
www.biorxiv.org
January 5, 2026 at 1:49 AM
Happy new year! The second big project of my PhD in Rachel Whitaker's lab is now up! 🎉 We look at how provirus infection affects the evolution of the bacterial chromosome with different types of viral induction – with CRISPRs or antibiotics. Take a peek 🦠 www.biorxiv.org/content/10.6...
🦠 El #CSIC crea un #anticuerpo que protege in vitro a las células del sistema inmune de una peligrosa bacteria hospitalaria
👩🔬 El anticuerpo del IQAC_CSIC reduce la virulencia de Pseudomonas aeruginosa sin provocar resistencia a antibióticos
👉 http://tiny.cc/kaiz001
👩🔬 El anticuerpo del IQAC_CSIC reduce la virulencia de Pseudomonas aeruginosa sin provocar resistencia a antibióticos
👉 http://tiny.cc/kaiz001
February 26, 2026 at 11:15 AM
🦠 El #CSIC crea un #anticuerpo que protege in vitro a las células del sistema inmune de una peligrosa bacteria hospitalaria
👩🔬 El anticuerpo del IQAC_CSIC reduce la virulencia de Pseudomonas aeruginosa sin provocar resistencia a antibióticos
👉 http://tiny.cc/kaiz001
👩🔬 El anticuerpo del IQAC_CSIC reduce la virulencia de Pseudomonas aeruginosa sin provocar resistencia a antibióticos
👉 http://tiny.cc/kaiz001
The final version of our latest paper is now published in @natcomms.nature.com!
This study illustrates how #AntibioticResistance mechanisms can reshape bacterial physiology beyond resistance itself, ultimately influencing infection dynamics in clinically relevant ways🦠
www.nature.com/articles/s41...
This study illustrates how #AntibioticResistance mechanisms can reshape bacterial physiology beyond resistance itself, ultimately influencing infection dynamics in clinically relevant ways🦠
www.nature.com/articles/s41...
June 9, 2026 at 8:38 AM
The final version of our latest paper is now published in @natcomms.nature.com!
This study illustrates how #AntibioticResistance mechanisms can reshape bacterial physiology beyond resistance itself, ultimately influencing infection dynamics in clinically relevant ways🦠
www.nature.com/articles/s41...
This study illustrates how #AntibioticResistance mechanisms can reshape bacterial physiology beyond resistance itself, ultimately influencing infection dynamics in clinically relevant ways🦠
www.nature.com/articles/s41...
New 🧫🦠🧪 paper from the lab:
Targeted deletion of Pf prophages from diverse Pseudomonas aeruginosa isolates impacts quorum sensing and virulence traits
doi.org/10.1101/2023...
#phagesky
#microsky
Targeted deletion of Pf prophages from diverse Pseudomonas aeruginosa isolates impacts quorum sensing and virulence traits
doi.org/10.1101/2023...
#phagesky
#microsky
November 20, 2023 at 2:13 PM
New 🧫🦠🧪 paper from the lab:
Targeted deletion of Pf prophages from diverse Pseudomonas aeruginosa isolates impacts quorum sensing and virulence traits
doi.org/10.1101/2023...
#phagesky
#microsky
Targeted deletion of Pf prophages from diverse Pseudomonas aeruginosa isolates impacts quorum sensing and virulence traits
doi.org/10.1101/2023...
#phagesky
#microsky
New 𝘕𝘢𝘵𝘶𝘳𝘦 𝘔𝘦𝘥𝘪𝘤𝘪𝘯𝘦 🦠
Personalized Nebulized Bacteriophage Therapy for MDR 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 Infections in Cystic Fibrosis
In 9 patients, 10²–10⁴ CFU/mL drop in sputum bacteria, 6% median gain in FEV1
Post-treatment isolates showed trade-offs—reduced virulence, increased antibiotic susceptibility
Personalized Nebulized Bacteriophage Therapy for MDR 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 Infections in Cystic Fibrosis
In 9 patients, 10²–10⁴ CFU/mL drop in sputum bacteria, 6% median gain in FEV1
Post-treatment isolates showed trade-offs—reduced virulence, increased antibiotic susceptibility
Personalized inhaled bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa in cystic fibrosis - Nature Medicine
A novel personalized phage therapy strategy that selects phages for a predicted evolutionary trade-off may represent a viable alternative approach for the treatment of antimicrobial-resistant bacteria...
www.nature.com
May 4, 2025 at 3:27 PM
New 𝘕𝘢𝘵𝘶𝘳𝘦 𝘔𝘦𝘥𝘪𝘤𝘪𝘯𝘦 🦠
Personalized Nebulized Bacteriophage Therapy for MDR 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 Infections in Cystic Fibrosis
In 9 patients, 10²–10⁴ CFU/mL drop in sputum bacteria, 6% median gain in FEV1
Post-treatment isolates showed trade-offs—reduced virulence, increased antibiotic susceptibility
Personalized Nebulized Bacteriophage Therapy for MDR 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 Infections in Cystic Fibrosis
In 9 patients, 10²–10⁴ CFU/mL drop in sputum bacteria, 6% median gain in FEV1
Post-treatment isolates showed trade-offs—reduced virulence, increased antibiotic susceptibility
Cool 🦠
William Schmidt
Gerard Wong Lab @UCLA
Nature Microbiology
Pseudomonas aeruginosa lays down Psl exopolysaccharide as it crawls
Other cells detect and follow these trails using type IV pili pulling against adhesins like CdrA triggering c-di-GMP & cAMP surges to shift into early biofilm mode
William Schmidt
Gerard Wong Lab @UCLA
Nature Microbiology
Pseudomonas aeruginosa lays down Psl exopolysaccharide as it crawls
Other cells detect and follow these trails using type IV pili pulling against adhesins like CdrA triggering c-di-GMP & cAMP surges to shift into early biofilm mode
Pseudomonas aeruginosa senses exopolysaccharide trails using type IV pili and adhesins during biofilm formation - Nature Microbiology
Opposing forces generated by exopolysaccharide trail binding versus type IV pilus retraction generate a high cyclic diGMP–high cyclic AMP state in Pseudomonas aeruginosa that promotes social motility.
www.nature.com
October 29, 2025 at 3:41 AM
Cool 🦠
William Schmidt
Gerard Wong Lab @UCLA
Nature Microbiology
Pseudomonas aeruginosa lays down Psl exopolysaccharide as it crawls
Other cells detect and follow these trails using type IV pili pulling against adhesins like CdrA triggering c-di-GMP & cAMP surges to shift into early biofilm mode
William Schmidt
Gerard Wong Lab @UCLA
Nature Microbiology
Pseudomonas aeruginosa lays down Psl exopolysaccharide as it crawls
Other cells detect and follow these trails using type IV pili pulling against adhesins like CdrA triggering c-di-GMP & cAMP surges to shift into early biofilm mode
Congrats to Garret for officially becoming Dr. O'Connell! Garret had his Ph.D. viva on synthetic #fluorochemical #metabolism in #Pseudomonas today. Thanks to @tilmweber.bsky.social r.bsky.social, @pavelcito.bsky.social & Esteban Martinez for their insights🧪🦠 #SynBio @labnikel.bsky.social
March 17, 2025 at 9:00 PM
Congrats to Garret for officially becoming Dr. O'Connell! Garret had his Ph.D. viva on synthetic #fluorochemical #metabolism in #Pseudomonas today. Thanks to @tilmweber.bsky.social r.bsky.social, @pavelcito.bsky.social & Esteban Martinez for their insights🧪🦠 #SynBio @labnikel.bsky.social
Clinical isolate of 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 🦠 eats plastic used in IV and urinary catheters
PA-W23 degrades medical-grade polycaprolactone (PCL) by 78% in just 7 days—using it as its sole carbon source
Worse yet—the plastic diet enhances biofilm formation
𝘾𝙀𝙇𝙇 𝙍𝙀𝙋𝙊𝙍𝙏𝙎
www.cell.com/cell-reports...
PA-W23 degrades medical-grade polycaprolactone (PCL) by 78% in just 7 days—using it as its sole carbon source
Worse yet—the plastic diet enhances biofilm formation
𝘾𝙀𝙇𝙇 𝙍𝙀𝙋𝙊𝙍𝙏𝙎
www.cell.com/cell-reports...
May 12, 2025 at 6:41 PM
Clinical isolate of 𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 🦠 eats plastic used in IV and urinary catheters
PA-W23 degrades medical-grade polycaprolactone (PCL) by 78% in just 7 days—using it as its sole carbon source
Worse yet—the plastic diet enhances biofilm formation
𝘾𝙀𝙇𝙇 𝙍𝙀𝙋𝙊𝙍𝙏𝙎
www.cell.com/cell-reports...
PA-W23 degrades medical-grade polycaprolactone (PCL) by 78% in just 7 days—using it as its sole carbon source
Worse yet—the plastic diet enhances biofilm formation
𝘾𝙀𝙇𝙇 𝙍𝙀𝙋𝙊𝙍𝙏𝙎
www.cell.com/cell-reports...
New preprint out! 📣🚨
We found that loss-of-function mutations in the carbapenem entry porin OprD of Pseudomonas aeruginosa do more than confer #AntibioticResistance: they reshape the bacterial membrane and interaction with the host, enhancing epithelial colonization capacity 🦠
#Microsky
We found that loss-of-function mutations in the carbapenem entry porin OprD of Pseudomonas aeruginosa do more than confer #AntibioticResistance: they reshape the bacterial membrane and interaction with the host, enhancing epithelial colonization capacity 🦠
#Microsky
Carbapenem-resistance oprD mutations reshape Pseudomonas aeruginosa host-pathogen interactions during infection https://www.biorxiv.org/content/10.1101/2025.10.24.684370v1
October 25, 2025 at 12:29 PM
New preprint out! 📣🚨
We found that loss-of-function mutations in the carbapenem entry porin OprD of Pseudomonas aeruginosa do more than confer #AntibioticResistance: they reshape the bacterial membrane and interaction with the host, enhancing epithelial colonization capacity 🦠
#Microsky
We found that loss-of-function mutations in the carbapenem entry porin OprD of Pseudomonas aeruginosa do more than confer #AntibioticResistance: they reshape the bacterial membrane and interaction with the host, enhancing epithelial colonization capacity 🦠
#Microsky