Refining RNA-Seq Transcriptome Profiles with Transcript-Specific Minimal-Shared Regions https://www.biorxiv.org/content/10.64898/2026.10.28.762701v1
November 3, 2026 at 6:47 AM
Refining RNA-Seq Transcriptome Profiles with Transcript-Specific Minimal-Shared Regions https://www.biorxiv.org/content/10.64898/2026.10.28.762701v1
who has a tutorial video/blogpost/github they like for learning to do bulk RNA-seq analysis?
(pls re-ski!)
(pls re-ski!)
October 30, 2026 at 11:54 PM
who has a tutorial video/blogpost/github they like for learning to do bulk RNA-seq analysis?
(pls re-ski!)
(pls re-ski!)
SQANTI-evidence: isoform-resolved, evidence-tiered structural annotation of unannotated genomes from long-read RNA-seq https://www.biorxiv.org/content/10.64898/2026.11.01.763455v1
November 4, 2026 at 3:46 PM
SQANTI-evidence: isoform-resolved, evidence-tiered structural annotation of unannotated genomes from long-read RNA-seq https://www.biorxiv.org/content/10.64898/2026.11.01.763455v1
If you want a deep dive, the Griffith lab has rnabio.org
RNA-seq
The RNAbio.org site is meant to accompany RNA-seq workshops delivered at various times during the year at various places (New York, Toronto, Germany, Glasgow, etc) in collaboration with various bioinf...
rnabio.org
November 2, 2026 at 2:15 PM
If you want a deep dive, the Griffith lab has rnabio.org
📝 RNA sequencing reveals functional gene similarities across species
✍️ RNA-Seq Blog
✍️ RNA-Seq Blog
RNA sequencing reveals functional gene similarities across species
Article de RNA-Seq Blog
www.rna-seqblog.com
November 3, 2026 at 8:51 AM
📝 RNA sequencing reveals functional gene similarities across species
✍️ RNA-Seq Blog
✍️ RNA-Seq Blog
The de-seq tutorial is pretty good but doesn't include the read counting step
bioconductor.org/packages/dev...
bioconductor.org/packages/dev...
Analyzing RNA-seq data with DESeq2
bioconductor.org
October 31, 2026 at 12:09 AM
The de-seq tutorial is pretty good but doesn't include the read counting step
bioconductor.org/packages/dev...
bioconductor.org/packages/dev...
🎤 Coming up at #LRUA26!
📅 Tuesday 3 November · 14:15–14:30
📍 Breakout session: Long-read RNA & Single-cell · Sal IX
#LongTREC Supervisor Wilfried Haerty will present:
"Reading between the isoforms: a comparison of long read RNA-Seq approaches"
#LongTREC #LRUA26 #LongReadSequencing
📅 Tuesday 3 November · 14:15–14:30
📍 Breakout session: Long-read RNA & Single-cell · Sal IX
#LongTREC Supervisor Wilfried Haerty will present:
"Reading between the isoforms: a comparison of long read RNA-Seq approaches"
#LongTREC #LRUA26 #LongReadSequencing
November 3, 2026 at 9:34 AM
🎤 Coming up at #LRUA26!
📅 Tuesday 3 November · 14:15–14:30
📍 Breakout session: Long-read RNA & Single-cell · Sal IX
#LongTREC Supervisor Wilfried Haerty will present:
"Reading between the isoforms: a comparison of long read RNA-Seq approaches"
#LongTREC #LRUA26 #LongReadSequencing
📅 Tuesday 3 November · 14:15–14:30
📍 Breakout session: Long-read RNA & Single-cell · Sal IX
#LongTREC Supervisor Wilfried Haerty will present:
"Reading between the isoforms: a comparison of long read RNA-Seq approaches"
#LongTREC #LRUA26 #LongReadSequencing
Stuck on an RNA-Seq question? Ask our Plasmidsaurus RNA-Seq product team during our virtual user group meeting on November 12.
Submit your questions on the event page when you register!
🔗 plasmidsaurus.com/events/rna-s...
Submit your questions on the event page when you register!
🔗 plasmidsaurus.com/events/rna-s...
October 30, 2026 at 4:49 PM
Stuck on an RNA-Seq question? Ask our Plasmidsaurus RNA-Seq product team during our virtual user group meeting on November 12.
Submit your questions on the event page when you register!
🔗 plasmidsaurus.com/events/rna-s...
Submit your questions on the event page when you register!
🔗 plasmidsaurus.com/events/rna-s...
📝 Researchers create first whole-body single-cell atlas of an adult vertebrate
✍️ RNA-Seq Blog
✍️ RNA-Seq Blog
Researchers create first whole-body single-cell atlas of an adult vertebrate
Article de RNA-Seq Blog
www.rna-seqblog.com
November 3, 2026 at 8:51 AM
📝 Researchers create first whole-body single-cell atlas of an adult vertebrate
✍️ RNA-Seq Blog
✍️ RNA-Seq Blog
🚨 Last seats available!
Ready to dive into single-cell RNA-seq? 🧬 Join our hands-on single-cell RNA-seq Analysis with R & @bioconductor.bsky.social workshop, 16–20 November, online.
Learn QC, clustering, cell annotation, differential expression & more!
www.physalia-courses.org/courses-work...
Ready to dive into single-cell RNA-seq? 🧬 Join our hands-on single-cell RNA-seq Analysis with R & @bioconductor.bsky.social workshop, 16–20 November, online.
Learn QC, clustering, cell annotation, differential expression & more!
www.physalia-courses.org/courses-work...
November 4, 2026 at 2:21 PM
🚨 Last seats available!
Ready to dive into single-cell RNA-seq? 🧬 Join our hands-on single-cell RNA-seq Analysis with R & @bioconductor.bsky.social workshop, 16–20 November, online.
Learn QC, clustering, cell annotation, differential expression & more!
www.physalia-courses.org/courses-work...
Ready to dive into single-cell RNA-seq? 🧬 Join our hands-on single-cell RNA-seq Analysis with R & @bioconductor.bsky.social workshop, 16–20 November, online.
Learn QC, clustering, cell annotation, differential expression & more!
www.physalia-courses.org/courses-work...
New D&D-seq method reveals single-cell DNA-protein interactions, capturing transient TF binding insights. Key to understanding gene regulation dynamics! PMID:42242226, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00573-8 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00573-8
No description available
www.cell.com
November 3, 2026 at 11:00 AM
Refining RNA-Seq Transcriptome Profiles with Transcript-Specific Minimal-Shared Regions https://www.biorxiv.org/content/10.64898/2026.10.28.762701v1
November 3, 2026 at 6:47 AM
Refining RNA-Seq Transcriptome Profiles with Transcript-Specific Minimal-Shared Regions https://www.biorxiv.org/content/10.64898/2026.10.28.762701v1
Efficient protocol transitions human pluripotent stem cells to naive state in just 12 days. Key: chromatin rewiring, increased accessibility at OCT/KLF, and NFκB inhibition. PMID:42414293, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-74432-y #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
Delicate inhibition of NFκB/RELA circuitry facilitates efficient transition towards ground-state pluripotency in human | Nature Communications
Rebuilding human naïve pluripotency from primed stem cells is essential for generating pre-implantation epiblast-like cells, a key source for regenerative medicine. Here we present a defined, feeder-free protocol that efficiently converts primed human pluripotent stem cells (hPSCs) to a naïve-like state within 12 days. Integrated ATAC-seq, RNA-seq and miRNA-seq analyses reveal a rapid chromatin rewiring marked by increased accessibility at OCT/KLF motifs, closure at ZIC/RFX/NFκB sites, upregulation of miR-372/373 and miR-182/183, and downregulation of miR-302 and miR-363/106 clusters. Functional assays demonstrate that the inflammatory transcription factor NFκB/RELA blocks naïve induction by activating peri-implantation barrier genes, including IKBKE and VEGFR1. Conversely, enforced miR-372/373 expression accelerates conversion by directly targeting RELA. These data delineate an NFκB/RELA axis that orchestrates the epigenetic switch to human naïve pluripotency, offering a tractable fra
doi.org
November 2, 2026 at 8:00 AM
Bulk vs Single-cell RNA-seq. What are they, what are they for and when do you use them?
One of the members of our science team, Christiana Iosef D.V.M., Ph.D, breaks it down for you in a new blog post.
Come check it out
advaitabio.com/iscanguide/s...
One of the members of our science team, Christiana Iosef D.V.M., Ph.D, breaks it down for you in a new blog post.
Come check it out
advaitabio.com/iscanguide/s...
Single-Cell vs. Bulk RNA-Seq: When Each Makes Sense - Advaita Bioinformatics
Compare bulk and single-cell RNA-seq by cost and resolution, and learn when combining both delivers the strongest results.
advaitabio.com
November 4, 2026 at 4:47 PM
Bulk vs Single-cell RNA-seq. What are they, what are they for and when do you use them?
One of the members of our science team, Christiana Iosef D.V.M., Ph.D, breaks it down for you in a new blog post.
Come check it out
advaitabio.com/iscanguide/s...
One of the members of our science team, Christiana Iosef D.V.M., Ph.D, breaks it down for you in a new blog post.
Come check it out
advaitabio.com/iscanguide/s...
SQANTI-evidence: isoform-resolved, evidence-tiered structural annotation of unannotated genomes from long-read RNA-seq https://www.biorxiv.org/content/10.64898/2026.11.01.763455v1
November 4, 2026 at 3:46 PM
SQANTI-evidence: isoform-resolved, evidence-tiered structural annotation of unannotated genomes from long-read RNA-seq https://www.biorxiv.org/content/10.64898/2026.11.01.763455v1
Refining RNA-Seq Transcriptome Profiles with Transcript-Specific Minimal-Shared Regions #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2026.10.28.762701v1
https://www.biorxiv.org/content/10.64898/2026.10.28.762701v1
November 3, 2026 at 8:01 AM
Refining RNA-Seq Transcriptome Profiles with Transcript-Specific Minimal-Shared Regions #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2026.10.28.762701v1
https://www.biorxiv.org/content/10.64898/2026.10.28.762701v1
A novel single-cell tech, D&D-seq, maps transient DNA-protein interactions, revealing how TFs shape gene expression via chromatin dynamics. Key insights await! PMID:42242226, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00573-8 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00573-8
No description available
www.cell.com
November 1, 2026 at 11:00 PM
How much of the real cellular story does an RNA-seq gene list actually tell? 🧬💻
As a Junior TBS member (@tbsjunior.bsky.social), I shared a new piece on the FEBS Network on moving beyond p-values to true biological mechanisms! ✨
🔗 network.febs.org/posts/beyond...
#Bioinformatics #FEBSNetwork
As a Junior TBS member (@tbsjunior.bsky.social), I shared a new piece on the FEBS Network on moving beyond p-values to true biological mechanisms! ✨
🔗 network.febs.org/posts/beyond...
#Bioinformatics #FEBSNetwork
November 4, 2026 at 9:32 PM
How much of the real cellular story does an RNA-seq gene list actually tell? 🧬💻
As a Junior TBS member (@tbsjunior.bsky.social), I shared a new piece on the FEBS Network on moving beyond p-values to true biological mechanisms! ✨
🔗 network.febs.org/posts/beyond...
#Bioinformatics #FEBSNetwork
As a Junior TBS member (@tbsjunior.bsky.social), I shared a new piece on the FEBS Network on moving beyond p-values to true biological mechanisms! ✨
🔗 network.febs.org/posts/beyond...
#Bioinformatics #FEBSNetwork
A multi-tissue RNA-seq atlas of adult medaka (Oryzias latipes) under salinity and winter-summer sampling contrasts https://www.biorxiv.org/content/10.64898/2026.10.27.762344v1
November 3, 2026 at 2:30 AM
A multi-tissue RNA-seq atlas of adult medaka (Oryzias latipes) under salinity and winter-summer sampling contrasts https://www.biorxiv.org/content/10.64898/2026.10.27.762344v1
NEPTUNE: a neuronal cell death pathway prediction tool used to decipher neurodegeneration using single cell RNA-seq datasets https://www.biorxiv.org/content/10.64898/2026.10.31.763288v1
November 3, 2026 at 7:48 AM
NEPTUNE: a neuronal cell death pathway prediction tool used to decipher neurodegeneration using single cell RNA-seq datasets https://www.biorxiv.org/content/10.64898/2026.10.31.763288v1
NEPTUNE: a neuronal cell death pathway prediction tool used to decipher neurodegeneration using single cell RNA-seq datasets https://www.biorxiv.org/content/10.64898/2026.10.31.763288v1
November 3, 2026 at 7:48 AM
NEPTUNE: a neuronal cell death pathway prediction tool used to decipher neurodegeneration using single cell RNA-seq datasets https://www.biorxiv.org/content/10.64898/2026.10.31.763288v1
Learn RNA-seq: From FASTQ to Counts at your own pace!
#Research #Instats
Full details and registration in the first reply.
#Research #Instats
Full details and registration in the first reply.
October 31, 2026 at 1:40 PM
Learn RNA-seq: From FASTQ to Counts at your own pace!
#Research #Instats
Full details and registration in the first reply.
#Research #Instats
Full details and registration in the first reply.
Differential Gene Expression and Functional Enrichment Analysis of Breast Tumor and Normal Tissue RNA-seq Data: A Reanalysis of GEO Dataset GSE210787 https://www.biorxiv.org/content/10.64898/2026.10.29.762989v1
November 4, 2026 at 4:46 PM
Differential Gene Expression and Functional Enrichment Analysis of Breast Tumor and Normal Tissue RNA-seq Data: A Reanalysis of GEO Dataset GSE210787 https://www.biorxiv.org/content/10.64898/2026.10.29.762989v1
A multi-tissue RNA-seq atlas of adult medaka (Oryzias latipes) under salinity and winter-summer sampling contrasts https://www.biorxiv.org/content/10.64898/2026.10.27.762344v1
November 3, 2026 at 2:30 AM
A multi-tissue RNA-seq atlas of adult medaka (Oryzias latipes) under salinity and winter-summer sampling contrasts https://www.biorxiv.org/content/10.64898/2026.10.27.762344v1