Our work on cellular RNA interactions with MAVS that promote antiviral signaling is finally live. So grateful to our indispensable collaborators as well as reviewers who helped to strengthen our work. #RNA #innateimmunity #virology
@ramlabuw.bsky.social
www.science.org/doi/10.1126/...
@ramlabuw.bsky.social
www.science.org/doi/10.1126/...
Cellular RNA interacts with MAVS to promote antiviral signaling
Antiviral signaling downstream of RIG-I–like receptors (RLRs) proceeds through a multi-protein complex organized around the adaptor protein mitochondrial antiviral signaling protein (MAVS). Protein co...
www.science.org
December 19, 2024 at 8:34 PM
Hao's Preprint Reading List
June 27th, 2025
Construct a 20-µm endothelialized microchannel🤯
#RNAsensing #Atherosclerosis
Sheared Mφ & endothelial barrier
A 🐟 model of #MarfanSyndrome🤓
#YAP/TAZ #PulmonaryFibrosis
Mechano-metabolic coupling in kidney repair
docs.google.com/document/d/e...
June 27th, 2025
Construct a 20-µm endothelialized microchannel🤯
#RNAsensing #Atherosclerosis
Sheared Mφ & endothelial barrier
A 🐟 model of #MarfanSyndrome🤓
#YAP/TAZ #PulmonaryFibrosis
Mechano-metabolic coupling in kidney repair
docs.google.com/document/d/e...
June 27, 2025 at 10:59 AM
Hao's Preprint Reading List
June 27th, 2025
Construct a 20-µm endothelialized microchannel🤯
#RNAsensing #Atherosclerosis
Sheared Mφ & endothelial barrier
A 🐟 model of #MarfanSyndrome🤓
#YAP/TAZ #PulmonaryFibrosis
Mechano-metabolic coupling in kidney repair
docs.google.com/document/d/e...
June 27th, 2025
Construct a 20-µm endothelialized microchannel🤯
#RNAsensing #Atherosclerosis
Sheared Mφ & endothelial barrier
A 🐟 model of #MarfanSyndrome🤓
#YAP/TAZ #PulmonaryFibrosis
Mechano-metabolic coupling in kidney repair
docs.google.com/document/d/e...
🚨 New Commentary now online!
💭 CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
👉 buff.ly/XbmDlvT
🖊️ @eileenparkes.bsky.social
#RNAsensing #ChromosomalInstability
💭 CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
👉 buff.ly/XbmDlvT
🖊️ @eileenparkes.bsky.social
#RNAsensing #ChromosomalInstability
May 14, 2025 at 9:43 AM
🚨 New Commentary now online!
💭 CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
👉 buff.ly/XbmDlvT
🖊️ @eileenparkes.bsky.social
#RNAsensing #ChromosomalInstability
💭 CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability
👉 buff.ly/XbmDlvT
🖊️ @eileenparkes.bsky.social
#RNAsensing #ChromosomalInstability
Can we exploit anti-viral immunity to treat brain cancer? 🦠 🧠
Our last results suggest so, go ahead and check the paper if you’re curious! 🤓
www.cell.com/cell-reports...
#Brain_cancer #Glioblastoma #TumorMicroenvironment #RNAsensing #ADAR1
Our last results suggest so, go ahead and check the paper if you’re curious! 🤓
www.cell.com/cell-reports...
#Brain_cancer #Glioblastoma #TumorMicroenvironment #RNAsensing #ADAR1
Cancer cell and microenvironmental rewiring by ADAR1 loss impairs glioblastoma tumor growth and extends survival
Álvarez-Prado et al. report that targeting ADAR1 triggers cancer-cell-intrinsic anti-proliferative
mechanisms and fosters anti-tumoral immune responses, blocking tumor growth and extending
survival in...
www.cell.com
September 3, 2025 at 9:34 AM
Can we exploit anti-viral immunity to treat brain cancer? 🦠 🧠
Our last results suggest so, go ahead and check the paper if you’re curious! 🤓
www.cell.com/cell-reports...
#Brain_cancer #Glioblastoma #TumorMicroenvironment #RNAsensing #ADAR1
Our last results suggest so, go ahead and check the paper if you’re curious! 🤓
www.cell.com/cell-reports...
#Brain_cancer #Glioblastoma #TumorMicroenvironment #RNAsensing #ADAR1
This paper is very cool, and highlights the importance of #RNAsensing in the response to #mRNA #vaccines in the additional context of #cancer!
A paper in Nature reports that mRNA vaccines targeting SARS-CoV-2, COVID-19, also sensitize tumours to immune checkpoint inhibitors. #medsky 🧪
SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade - Nature
mRNA vaccines targeting SARS-CoV-2 also sensitize tumours to immune checkpoint inhibitors.
go.nature.com
October 29, 2025 at 5:18 AM
This paper is very cool, and highlights the importance of #RNAsensing in the response to #mRNA #vaccines in the additional context of #cancer!