Eric Dein @ericdeinmd
#RNL2025 Treatment of sclerosing skin conditions: Active inflammation? Sclerotic? Atrophic? Target based on activity, depth of involvement and other disease involvement
#RNL2025 Treatment of sclerosing skin conditions: Active inflammation? Sclerotic? Atrophic? Target based on activity, depth of involvement and other disease involvement
February 14, 2025 at 10:01 PM
Eric Dein @ericdeinmd
#RNL2025 Treatment of sclerosing skin conditions: Active inflammation? Sclerotic? Atrophic? Target based on activity, depth of involvement and other disease involvement
#RNL2025 Treatment of sclerosing skin conditions: Active inflammation? Sclerotic? Atrophic? Target based on activity, depth of involvement and other disease involvement
Eric Dein @ericdeinmd
How do you know if Morphea is active? -Erythema -Peripheral induration -New lesions in the past few month Non-active damage? - Dermal atrophy -SQ atrophy -Hyperpigmentation -Skin thickness center #RNL2025
How do you know if Morphea is active? -Erythema -Peripheral induration -New lesions in the past few month Non-active damage? - Dermal atrophy -SQ atrophy -Hyperpigmentation -Skin thickness center #RNL2025
February 14, 2025 at 7:00 PM
Eric Dein @ericdeinmd
How do you know if Morphea is active? -Erythema -Peripheral induration -New lesions in the past few month Non-active damage? - Dermal atrophy -SQ atrophy -Hyperpigmentation -Skin thickness center #RNL2025
How do you know if Morphea is active? -Erythema -Peripheral induration -New lesions in the past few month Non-active damage? - Dermal atrophy -SQ atrophy -Hyperpigmentation -Skin thickness center #RNL2025
The POWER of #plaquenil
#Hydroxychloroquine works in #rheumatic #diseases by
Old answer
👇
Alters liposomal membranes 🤷♀️
NEW ANSWER
Inhibits TLR signalling 🔥
#RNL2025 Mary *Peggy Crow #SLE #systemic #lupus #erythematosus
#Hydroxychloroquine works in #rheumatic #diseases by
Old answer
👇
Alters liposomal membranes 🤷♀️
NEW ANSWER
Inhibits TLR signalling 🔥
#RNL2025 Mary *Peggy Crow #SLE #systemic #lupus #erythematosus
February 13, 2025 at 10:02 PM
The POWER of #plaquenil
#Hydroxychloroquine works in #rheumatic #diseases by
Old answer
👇
Alters liposomal membranes 🤷♀️
NEW ANSWER
Inhibits TLR signalling 🔥
#RNL2025 Mary *Peggy Crow #SLE #systemic #lupus #erythematosus
#Hydroxychloroquine works in #rheumatic #diseases by
Old answer
👇
Alters liposomal membranes 🤷♀️
NEW ANSWER
Inhibits TLR signalling 🔥
#RNL2025 Mary *Peggy Crow #SLE #systemic #lupus #erythematosus
TheDaoIndex @KDAO2011
A practical clinic-based approach to assessing CVD, CA screening, lung disease, infections for rheums by Dr Bryant England who offers us menus.. start by asking about symptoms. #RNL2025
A practical clinic-based approach to assessing CVD, CA screening, lung disease, infections for rheums by Dr Bryant England who offers us menus.. start by asking about symptoms. #RNL2025
buff.ly
February 13, 2025 at 8:03 PM
TheDaoIndex @KDAO2011
A practical clinic-based approach to assessing CVD, CA screening, lung disease, infections for rheums by Dr Bryant England who offers us menus.. start by asking about symptoms. #RNL2025
A practical clinic-based approach to assessing CVD, CA screening, lung disease, infections for rheums by Dr Bryant England who offers us menus.. start by asking about symptoms. #RNL2025
RT @AdelaCastro222
Multimorbidity in Rheumatoid Arthritis:
-Affects >75% of pts
-Reduces quality of life and increases mortality
-Highly associated w/ D2T RA
-Requires multidisciplinary care teams (PCP, specialists, case management, PT)
-Management should start early in the disease
#RNL2025
Multimorbidity in Rheumatoid Arthritis:
-Affects >75% of pts
-Reduces quality of life and increases mortality
-Highly associated w/ D2T RA
-Requires multidisciplinary care teams (PCP, specialists, case management, PT)
-Management should start early in the disease
#RNL2025
February 13, 2025 at 7:01 PM
RT @AdelaCastro222
Multimorbidity in Rheumatoid Arthritis:
-Affects >75% of pts
-Reduces quality of life and increases mortality
-Highly associated w/ D2T RA
-Requires multidisciplinary care teams (PCP, specialists, case management, PT)
-Management should start early in the disease
#RNL2025
Multimorbidity in Rheumatoid Arthritis:
-Affects >75% of pts
-Reduces quality of life and increases mortality
-Highly associated w/ D2T RA
-Requires multidisciplinary care teams (PCP, specialists, case management, PT)
-Management should start early in the disease
#RNL2025
Jeffrey Curtis @RADoctor
Great talk at #RNL2025 by Dr Una Makris on managing geriatric rheumatology patients. How often do we under-treat #Rheumatoid arthritis patients with advanced therapies because we fall into the trap of ageism?
Great talk at #RNL2025 by Dr Una Makris on managing geriatric rheumatology patients. How often do we under-treat #Rheumatoid arthritis patients with advanced therapies because we fall into the trap of ageism?
buff.ly
February 13, 2025 at 5:01 PM
Jeffrey Curtis @RADoctor
Great talk at #RNL2025 by Dr Una Makris on managing geriatric rheumatology patients. How often do we under-treat #Rheumatoid arthritis patients with advanced therapies because we fall into the trap of ageism?
Great talk at #RNL2025 by Dr Una Makris on managing geriatric rheumatology patients. How often do we under-treat #Rheumatoid arthritis patients with advanced therapies because we fall into the trap of ageism?
Janet Pope @Janetbirdope
Dispel the #myth #rheumatoid #arthritis is NOT Just a disease of Young and middle aged Elderly PREVALENT #RA Pts and 👇 INCIDENT Pts in >65yrs is skyrocketing 🚀 Need #Rx goals and equitable #Rx Uma Makris #RNL2025
Dispel the #myth #rheumatoid #arthritis is NOT Just a disease of Young and middle aged Elderly PREVALENT #RA Pts and 👇 INCIDENT Pts in >65yrs is skyrocketing 🚀 Need #Rx goals and equitable #Rx Uma Makris #RNL2025
buff.ly
February 13, 2025 at 4:10 PM
Janet Pope @Janetbirdope
Dispel the #myth #rheumatoid #arthritis is NOT Just a disease of Young and middle aged Elderly PREVALENT #RA Pts and 👇 INCIDENT Pts in >65yrs is skyrocketing 🚀 Need #Rx goals and equitable #Rx Uma Makris #RNL2025
Dispel the #myth #rheumatoid #arthritis is NOT Just a disease of Young and middle aged Elderly PREVALENT #RA Pts and 👇 INCIDENT Pts in >65yrs is skyrocketing 🚀 Need #Rx goals and equitable #Rx Uma Makris #RNL2025
TheDaoIndex @KDAO2011
@UnaMakris wants us to shift our approach to #GeriRheum. #RNL2025– remember the 5 M’s Multimorbidity Mind Medications Mobility what Matters most
@UnaMakris wants us to shift our approach to #GeriRheum. #RNL2025– remember the 5 M’s Multimorbidity Mind Medications Mobility what Matters most
buff.ly
February 13, 2025 at 3:03 PM
TheDaoIndex @KDAO2011
@UnaMakris wants us to shift our approach to #GeriRheum. #RNL2025– remember the 5 M’s Multimorbidity Mind Medications Mobility what Matters most
@UnaMakris wants us to shift our approach to #GeriRheum. #RNL2025– remember the 5 M’s Multimorbidity Mind Medications Mobility what Matters most
Adela Castro @AdelaCastro222
Are your patients aging with RA, or are they diagnosed with Late Onset RA (LORA)? -LORA pts tend to present acutely -High inflammatory markers~PMR Like -Seronegative/Decreased titers of RF/CCP @UnaMakris #RNL2025
Are your patients aging with RA, or are they diagnosed with Late Onset RA (LORA)? -LORA pts tend to present acutely -High inflammatory markers~PMR Like -Seronegative/Decreased titers of RF/CCP @UnaMakris #RNL2025
buff.ly
February 12, 2025 at 4:04 PM
Adela Castro @AdelaCastro222
Are your patients aging with RA, or are they diagnosed with Late Onset RA (LORA)? -LORA pts tend to present acutely -High inflammatory markers~PMR Like -Seronegative/Decreased titers of RF/CCP @UnaMakris #RNL2025
Are your patients aging with RA, or are they diagnosed with Late Onset RA (LORA)? -LORA pts tend to present acutely -High inflammatory markers~PMR Like -Seronegative/Decreased titers of RF/CCP @UnaMakris #RNL2025
@ericdeinmd
J Curtis #RNL2025 AI Will Not Replace You - AI cannot replace human interaction, examination, procedures, interpreting guidelines for an individual, providing empathy, and facilitate good patient education Will become a tool... but not a replacement to a good clinician
J Curtis #RNL2025 AI Will Not Replace You - AI cannot replace human interaction, examination, procedures, interpreting guidelines for an individual, providing empathy, and facilitate good patient education Will become a tool... but not a replacement to a good clinician
buff.ly
February 12, 2025 at 12:01 AM
@ericdeinmd
J Curtis #RNL2025 AI Will Not Replace You - AI cannot replace human interaction, examination, procedures, interpreting guidelines for an individual, providing empathy, and facilitate good patient education Will become a tool... but not a replacement to a good clinician
J Curtis #RNL2025 AI Will Not Replace You - AI cannot replace human interaction, examination, procedures, interpreting guidelines for an individual, providing empathy, and facilitate good patient education Will become a tool... but not a replacement to a good clinician
@ericdeinmd
AI models require good Positive Predictive Value (PPV) But: PPV decreases as prevalence decreases - In choosing a successful biologic: Harder to predict more challenging patients (multiple failures, co-morbidities, etc) - ACR50 non-response is higher J Curtis #RNL2025
AI models require good Positive Predictive Value (PPV) But: PPV decreases as prevalence decreases - In choosing a successful biologic: Harder to predict more challenging patients (multiple failures, co-morbidities, etc) - ACR50 non-response is higher J Curtis #RNL2025
buff.ly
February 11, 2025 at 8:02 PM
@ericdeinmd
AI models require good Positive Predictive Value (PPV) But: PPV decreases as prevalence decreases - In choosing a successful biologic: Harder to predict more challenging patients (multiple failures, co-morbidities, etc) - ACR50 non-response is higher J Curtis #RNL2025
AI models require good Positive Predictive Value (PPV) But: PPV decreases as prevalence decreases - In choosing a successful biologic: Harder to predict more challenging patients (multiple failures, co-morbidities, etc) - ACR50 non-response is higher J Curtis #RNL2025
@AdelaCastro222
How can AI be useful for RA pts and rheumatologists? -AI models have the potential for improving diagnosis, management and outcomes in RA pts. -Can also improve efficiency and clinic workflow. -Not so perfect as it sounds (hallucinations, limited accuracy) #RNL2025
How can AI be useful for RA pts and rheumatologists? -AI models have the potential for improving diagnosis, management and outcomes in RA pts. -Can also improve efficiency and clinic workflow. -Not so perfect as it sounds (hallucinations, limited accuracy) #RNL2025
buff.ly
February 11, 2025 at 7:03 PM
@AdelaCastro222
How can AI be useful for RA pts and rheumatologists? -AI models have the potential for improving diagnosis, management and outcomes in RA pts. -Can also improve efficiency and clinic workflow. -Not so perfect as it sounds (hallucinations, limited accuracy) #RNL2025
How can AI be useful for RA pts and rheumatologists? -AI models have the potential for improving diagnosis, management and outcomes in RA pts. -Can also improve efficiency and clinic workflow. -Not so perfect as it sounds (hallucinations, limited accuracy) #RNL2025
@ericdeinmd
🏈Kick-off of @RheumNow w Jeff Curtis #RNL2025 🏈 AI in RA? Can help with Rheum Boards Questions, though AI is not confident in answers May not be better than paper charts for triage Other roles: pt chatbot, AI scribe, research populations, generate DDx, consume guidelines
🏈Kick-off of @RheumNow w Jeff Curtis #RNL2025 🏈 AI in RA? Can help with Rheum Boards Questions, though AI is not confident in answers May not be better than paper charts for triage Other roles: pt chatbot, AI scribe, research populations, generate DDx, consume guidelines
buff.ly
February 11, 2025 at 5:00 PM
@ericdeinmd
🏈Kick-off of @RheumNow w Jeff Curtis #RNL2025 🏈 AI in RA? Can help with Rheum Boards Questions, though AI is not confident in answers May not be better than paper charts for triage Other roles: pt chatbot, AI scribe, research populations, generate DDx, consume guidelines
🏈Kick-off of @RheumNow w Jeff Curtis #RNL2025 🏈 AI in RA? Can help with Rheum Boards Questions, though AI is not confident in answers May not be better than paper charts for triage Other roles: pt chatbot, AI scribe, research populations, generate DDx, consume guidelines
Great weekend #RNL2025
Speaking about geriatrics concepts we can integrate into our care to improve outcomes for older adults with rheumatic disease.
Thank you to this engaged audience early Sat morning 🙌🙌
@rheumnow.bsky.social @kwyshammd.bsky.social
Credit to #gerirheum for moving us forward
Speaking about geriatrics concepts we can integrate into our care to improve outcomes for older adults with rheumatic disease.
Thank you to this engaged audience early Sat morning 🙌🙌
@rheumnow.bsky.social @kwyshammd.bsky.social
Credit to #gerirheum for moving us forward
February 10, 2025 at 1:11 AM
Great weekend #RNL2025
Speaking about geriatrics concepts we can integrate into our care to improve outcomes for older adults with rheumatic disease.
Thank you to this engaged audience early Sat morning 🙌🙌
@rheumnow.bsky.social @kwyshammd.bsky.social
Credit to #gerirheum for moving us forward
Speaking about geriatrics concepts we can integrate into our care to improve outcomes for older adults with rheumatic disease.
Thank you to this engaged audience early Sat morning 🙌🙌
@rheumnow.bsky.social @kwyshammd.bsky.social
Credit to #gerirheum for moving us forward
80% #hydradenitis suppurativa pts are smokers or former smokers, smoking can predate #HS by 4-5 years. Other associations: DM-2, Spa, obesity, SAPHO, PCOS eval for SCC (squ. cell CA) #RNL2025
@rheumnow.bsky.social
@rheumnow.bsky.social
February 9, 2025 at 3:58 PM
80% #hydradenitis suppurativa pts are smokers or former smokers, smoking can predate #HS by 4-5 years. Other associations: DM-2, Spa, obesity, SAPHO, PCOS eval for SCC (squ. cell CA) #RNL2025
@rheumnow.bsky.social
@rheumnow.bsky.social
"Tombstone comedones" (2 comodones together) are pathognomonic of #Hydradenitis - Dr. J Cather #RNL2025
@rheumnow.bsky.social
@rheumnow.bsky.social
February 9, 2025 at 3:57 PM
"Tombstone comedones" (2 comodones together) are pathognomonic of #Hydradenitis - Dr. J Cather #RNL2025
@rheumnow.bsky.social
@rheumnow.bsky.social
"Vinegar water or 1 tbs bleach to 1 gallon water can help with the odor from #Hidadrenitis" - Dr. J Cather reviewed goals of therapies and Rx's (while laser hair removal can help, it also can cause problems; intralesional steroids can cause atrophy)
@rheumnow.bsky.social
#RNL2025
@rheumnow.bsky.social
#RNL2025
February 9, 2025 at 3:56 PM
"Vinegar water or 1 tbs bleach to 1 gallon water can help with the odor from #Hidadrenitis" - Dr. J Cather reviewed goals of therapies and Rx's (while laser hair removal can help, it also can cause problems; intralesional steroids can cause atrophy)
@rheumnow.bsky.social
#RNL2025
@rheumnow.bsky.social
#RNL2025
Dr. C Bakewell's PEARLs on imaging in #ankspond & #PsA:
- PsA may have +HLA-B08 and B28 (esp if it looks like candle drip--not just B27)
- for PsA, up to 30% of pts will have spinal lesions without Si joint changes
- for AS, MRI SI joints, xray the spine #RNL2025
@rheumnow.bsky.social
- PsA may have +HLA-B08 and B28 (esp if it looks like candle drip--not just B27)
- for PsA, up to 30% of pts will have spinal lesions without Si joint changes
- for AS, MRI SI joints, xray the spine #RNL2025
@rheumnow.bsky.social
February 9, 2025 at 3:54 PM
Dr. C Bakewell's PEARLs on imaging in #ankspond & #PsA:
- PsA may have +HLA-B08 and B28 (esp if it looks like candle drip--not just B27)
- for PsA, up to 30% of pts will have spinal lesions without Si joint changes
- for AS, MRI SI joints, xray the spine #RNL2025
@rheumnow.bsky.social
- PsA may have +HLA-B08 and B28 (esp if it looks like candle drip--not just B27)
- for PsA, up to 30% of pts will have spinal lesions without Si joint changes
- for AS, MRI SI joints, xray the spine #RNL2025
@rheumnow.bsky.social
Can NSAIDS reduce the risk for progression in #ankylosingspondylitis? - Dr. Van Der Heidje #RNL2025
@rheumnow.bsky.social
@rheumnow.bsky.social
February 9, 2025 at 3:49 PM
Can NSAIDS reduce the risk for progression in #ankylosingspondylitis? - Dr. Van Der Heidje #RNL2025
@rheumnow.bsky.social
@rheumnow.bsky.social
What are RA flare risks? @rheumnow.bsky.social #RNL2025
February 9, 2025 at 3:47 PM
What are RA flare risks? @rheumnow.bsky.social #RNL2025
February 9, 2025 at 3:46 PM
WWJCD-- what would Jack Cush do? for RA flares #RNL2025 @rheumnow.bsky.social
February 9, 2025 at 3:45 PM
WWJCD-- what would Jack Cush do? for RA flares #RNL2025 @rheumnow.bsky.social
"NO guidelines address RA flares!" - @rheumnow.bsky.social
on how flares are perceived as bad and important, but yet, no standard definition, guidance on this #RNL2025
on how flares are perceived as bad and important, but yet, no standard definition, guidance on this #RNL2025
February 9, 2025 at 3:43 PM
"NO guidelines address RA flares!" - @rheumnow.bsky.social
on how flares are perceived as bad and important, but yet, no standard definition, guidance on this #RNL2025
on how flares are perceived as bad and important, but yet, no standard definition, guidance on this #RNL2025
#RNL2025. RA flare definition differs w/ clinical trial. Pt's flare definition is even more different. Recent study defined flare as sDAI >=4.7 or CDAI > =4.5. a longer flare is worse than a shorter flare. Can't rely on DAS28 & low correl w/VECTRA or biomarkers. @rheumnow.bsky.social
February 9, 2025 at 3:40 PM
#RNL2025. RA flare definition differs w/ clinical trial. Pt's flare definition is even more different. Recent study defined flare as sDAI >=4.7 or CDAI > =4.5. a longer flare is worse than a shorter flare. Can't rely on DAS28 & low correl w/VECTRA or biomarkers. @rheumnow.bsky.social