The latest update to the Reproductive Sciences starter pack. Let me know if you wish to be listed. 🧪
#ReproSky #Obsky #ObGynSky #Reproduction #placenta #pregnancy #ReproSci
go.bsky.app/R19Temj
#ReproSky #Obsky #ObGynSky #Reproduction #placenta #pregnancy #ReproSci
go.bsky.app/R19Temj
November 26, 2024 at 8:54 PM
The latest update to the Reproductive Sciences starter pack. Let me know if you wish to be listed. 🧪
#ReproSky #Obsky #ObGynSky #Reproduction #placenta #pregnancy #ReproSci
go.bsky.app/R19Temj
#ReproSky #Obsky #ObGynSky #Reproduction #placenta #pregnancy #ReproSci
go.bsky.app/R19Temj
Spermatozoa as harbingers of mortality: the curious link between semen quality and life expectancy
#ReproSky 🧪 #ReproSci #Aging #LifeExpectancy
academic.oup.com/humrep/artic...
#ReproSky 🧪 #ReproSci #Aging #LifeExpectancy
academic.oup.com/humrep/artic...
Spermatozoa as harbingers of mortality: the curious link between semen quality and life expectancy
This edition of Human Reproduction features an important publication highlighting the curious dose-dependent relationship that exists between semen quality
academic.oup.com
April 7, 2025 at 12:52 AM
Spermatozoa as harbingers of mortality: the curious link between semen quality and life expectancy
#ReproSky 🧪 #ReproSci #Aging #LifeExpectancy
academic.oup.com/humrep/artic...
#ReproSky 🧪 #ReproSci #Aging #LifeExpectancy
academic.oup.com/humrep/artic...
A major element of the effort is the ReproSci platform, an #OpenScience infrastructure where any field can catalogue studies, highlight claims, establish strength of evidence, and invite community comments & data.
reprosci.epfl.ch
ReproSci is there for the community to tackle pos result bias.
4/4
reprosci.epfl.ch
ReproSci is there for the community to tackle pos result bias.
4/4
reprosci.epfl.ch
January 24, 2026 at 8:01 AM
A major element of the effort is the ReproSci platform, an #OpenScience infrastructure where any field can catalogue studies, highlight claims, establish strength of evidence, and invite community comments & data.
reprosci.epfl.ch
ReproSci is there for the community to tackle pos result bias.
4/4
reprosci.epfl.ch
ReproSci is there for the community to tackle pos result bias.
4/4
1/ A field-wide audit of reproducibility in Drosophila immunity
The ReproSci project assessed how many claims from 400 papers had been verified by later research, and, in an accompanying study, tested those that remained uncorroborated.
🔗 elifesciences.org/reviewed-pre...
The ReproSci project assessed how many claims from 400 papers had been verified by later research, and, in an accompanying study, tested those that remained uncorroborated.
🔗 elifesciences.org/reviewed-pre...
January 23, 2026 at 9:02 PM
1/ A field-wide audit of reproducibility in Drosophila immunity
The ReproSci project assessed how many claims from 400 papers had been verified by later research, and, in an accompanying study, tested those that remained uncorroborated.
🔗 elifesciences.org/reviewed-pre...
The ReproSci project assessed how many claims from 400 papers had been verified by later research, and, in an accompanying study, tested those that remained uncorroborated.
🔗 elifesciences.org/reviewed-pre...
So, what did we do and find?
This was an effort in conceptual replication - not the precise effect size or significance, but rather, are the conclusions themselves reproducible using modern techniques and understandings?
The study covered an entire field from 1959-2011: #Drosophila immunity
3.1/n
This was an effort in conceptual replication - not the precise effect size or significance, but rather, are the conclusions themselves reproducible using modern techniques and understandings?
The study covered an entire field from 1959-2011: #Drosophila immunity
3.1/n
July 10, 2025 at 8:23 AM
So, what did we do and find?
This was an effort in conceptual replication - not the precise effect size or significance, but rather, are the conclusions themselves reproducible using modern techniques and understandings?
The study covered an entire field from 1959-2011: #Drosophila immunity
3.1/n
This was an effort in conceptual replication - not the precise effect size or significance, but rather, are the conclusions themselves reproducible using modern techniques and understandings?
The study covered an entire field from 1959-2011: #Drosophila immunity
3.1/n
Reporducibility in fly immunity. www.biorxiv.org/content/10.1... great paper. To me the fact that people who move between teams do better research is quite interesting. Collaboration imho is key to good science.
A retrospective analysis of 400 publications reveals patterns of irreproducibility across an entire life sciences research field
The ReproSci project retrospectively analyzed the reproducibility of 1006 claims from 400 papers published between 1959 and 2011 in the field of Drosophila immunity. This project attempts to provide a...
www.biorxiv.org
July 10, 2025 at 1:23 PM
Reporducibility in fly immunity. www.biorxiv.org/content/10.1... great paper. To me the fact that people who move between teams do better research is quite interesting. Collaboration imho is key to good science.
Ah, that we have done! The reprosci website (see thread 2/n) is not only this exact effort, but it is a crowdsourcing platform open to any field to produce its own reproducibility initiative.
All claims are logged with individual annotatable pages, open to community comments.
All claims are logged with individual annotatable pages, open to community comments.
July 10, 2025 at 2:31 PM
Ah, that we have done! The reprosci website (see thread 2/n) is not only this exact effort, but it is a crowdsourcing platform open to any field to produce its own reproducibility initiative.
All claims are logged with individual annotatable pages, open to community comments.
All claims are logged with individual annotatable pages, open to community comments.
Some tags
#Metascience #NewPI #Drosophila #Celegans #Zebrafish #Danio #Genetics #ReproSci #ResearchIntegrity #ScientificPublishing #SciPub #AcademicSky #Immunity #InnateImmunity #NewPI #PhDchat #Science #Replicability #Reproducibility #Science #OpenScience #ResearchWaste #OpenAccess
#Metascience #NewPI #Drosophila #Celegans #Zebrafish #Danio #Genetics #ReproSci #ResearchIntegrity #ScientificPublishing #SciPub #AcademicSky #Immunity #InnateImmunity #NewPI #PhDchat #Science #Replicability #Reproducibility #Science #OpenScience #ResearchWaste #OpenAccess
July 10, 2025 at 8:23 AM
Paper 2 is a greater focus on #metascience, investigating what factors are most correlated with work being reproducible.
The big takeaways? Author institution (driven by a few key authors) is the most significant correlate of irreproducibility. #ResearchIntegrity #SciPub #AcademicSky #NewPI
4.1/n
The big takeaways? Author institution (driven by a few key authors) is the most significant correlate of irreproducibility. #ResearchIntegrity #SciPub #AcademicSky #NewPI
4.1/n
A retrospective analysis of 400 publications reveals patterns of irreproducibility across an entire life sciences research field
The ReproSci project retrospectively analyzed the reproducibility of 1006 claims from 400 papers published between 1959 and 2011 in the field of Drosophila immunity. This project attempts to provide a...
www.biorxiv.org
July 10, 2025 at 8:23 AM
Paper 2 is a greater focus on #metascience, investigating what factors are most correlated with work being reproducible.
The big takeaways? Author institution (driven by a few key authors) is the most significant correlate of irreproducibility. #ResearchIntegrity #SciPub #AcademicSky #NewPI
4.1/n
The big takeaways? Author institution (driven by a few key authors) is the most significant correlate of irreproducibility. #ResearchIntegrity #SciPub #AcademicSky #NewPI
4.1/n
The point we make in the reprosci papers is not "don't work across fields." But rather "the most reproducible work comes from folks who were raised in the field." Not surprising or controversial. 3/3
July 14, 2025 at 1:33 PM
The point we make in the reprosci papers is not "don't work across fields." But rather "the most reproducible work comes from folks who were raised in the field." Not surprising or controversial. 3/3
First, find the papers here:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
And the attached crowdsourced and community annotation website here:
reprosci.epfl.ch
^^ what's neat about the website is that it offers a platform for any field to attempt our approach organically.
2/n
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
And the attached crowdsourced and community annotation website here:
reprosci.epfl.ch
^^ what's neat about the website is that it offers a platform for any field to attempt our approach organically.
2/n
A retrospective analysis of 400 publications reveals patterns of irreproducibility across an entire life sciences research field
The ReproSci project retrospectively analyzed the reproducibility of 1006 claims from 400 papers published between 1959 and 2011 in the field of Drosophila immunity. This project attempts to provide a...
www.biorxiv.org
July 10, 2025 at 8:23 AM
First, find the papers here:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
And the attached crowdsourced and community annotation website here:
reprosci.epfl.ch
^^ what's neat about the website is that it offers a platform for any field to attempt our approach organically.
2/n
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
And the attached crowdsourced and community annotation website here:
reprosci.epfl.ch
^^ what's neat about the website is that it offers a platform for any field to attempt our approach organically.
2/n
So what can we do in response? A key problem:
The transformation from long- to short-term funding leads researchers to flit from topic to topic, and move across fields chasing 'sexy' stories.
Science is done better when you leave someone to geek out on a single topic for their whole career.
5/n
The transformation from long- to short-term funding leads researchers to flit from topic to topic, and move across fields chasing 'sexy' stories.
Science is done better when you leave someone to geek out on a single topic for their whole career.
5/n
July 10, 2025 at 8:23 AM
So what can we do in response? A key problem:
The transformation from long- to short-term funding leads researchers to flit from topic to topic, and move across fields chasing 'sexy' stories.
Science is done better when you leave someone to geek out on a single topic for their whole career.
5/n
The transformation from long- to short-term funding leads researchers to flit from topic to topic, and move across fields chasing 'sexy' stories.
Science is done better when you leave someone to geek out on a single topic for their whole career.
5/n
Qed seems interesting! Have you seen @brunolemaitre.bsky.social 's Reprosci site?
reprosci.epfl.ch
It's paired to preprints on fly immunity, but functionally it's a database of papers, their major/minor claims, and annotations of whether these have been supported by follow-up research. 1/2
reprosci.epfl.ch
It's paired to preprints on fly immunity, but functionally it's a database of papers, their major/minor claims, and annotations of whether these have been supported by follow-up research. 1/2
ReproSci
reprosci.epfl.ch
October 10, 2025 at 4:53 AM
Qed seems interesting! Have you seen @brunolemaitre.bsky.social 's Reprosci site?
reprosci.epfl.ch
It's paired to preprints on fly immunity, but functionally it's a database of papers, their major/minor claims, and annotations of whether these have been supported by follow-up research. 1/2
reprosci.epfl.ch
It's paired to preprints on fly immunity, but functionally it's a database of papers, their major/minor claims, and annotations of whether these have been supported by follow-up research. 1/2
Specifically on the #metascience side, congrats to @josephlemaitre.bsky.social and @brunolemaitre.bsky.social on this consequential piece. 🎉
By dissecting factors associated with #reproducibility within a single field, there are broad lessons for #ScientificPublishing and broader #science.
By dissecting factors associated with #reproducibility within a single field, there are broad lessons for #ScientificPublishing and broader #science.
July 10, 2025 at 12:58 PM
Specifically on the #metascience side, congrats to @josephlemaitre.bsky.social and @brunolemaitre.bsky.social on this consequential piece. 🎉
By dissecting factors associated with #reproducibility within a single field, there are broad lessons for #ScientificPublishing and broader #science.
By dissecting factors associated with #reproducibility within a single field, there are broad lessons for #ScientificPublishing and broader #science.
5/ All data are published on a publicly available website associated with this article that encourages community participation.
reprosci.epfl.ch
reprosci.epfl.ch
ReproSci
The purpose of the ReproSci reproducibility project is to determine whether a wide range of claims published in a given research field are verifiable using independent sources. As a first project we…
ReproSci.epfl.ch
January 23, 2026 at 9:02 PM
5/ All data are published on a publicly available website associated with this article that encourages community participation.
reprosci.epfl.ch
reprosci.epfl.ch
Indeed. The ReproSci site reprosci.epfl.ch is a bit of an experiment in that light. While it's an independent database (and so requires community buy-in), the goal is to allow more informal community notes on claims. Like that, the barrier to sharing concerns is lowered. Will it work? Who knows!
ReproSci
reprosci.epfl.ch
July 12, 2025 at 6:27 PM
Indeed. The ReproSci site reprosci.epfl.ch is a bit of an experiment in that light. While it's an independent database (and so requires community buy-in), the goal is to allow more informal community notes on claims. Like that, the barrier to sharing concerns is lowered. Will it work? Who knows!
Registration for #SSR2026 is LIVE! 🚀
Join us in Indianapolis (July 19-22) as we explore "Back to the Future: Foundational Knowledge for Future Innovations."
Early bird rates end June 1st! ⏳
Register: https://ssr.org/events/2026-annual-meeting/
#ReproSci #ScienceTwitter
Join us in Indianapolis (July 19-22) as we explore "Back to the Future: Foundational Knowledge for Future Innovations."
Early bird rates end June 1st! ⏳
Register: https://ssr.org/events/2026-annual-meeting/
#ReproSci #ScienceTwitter
March 20, 2026 at 2:02 PM
Registration for #SSR2026 is LIVE! 🚀
Join us in Indianapolis (July 19-22) as we explore "Back to the Future: Foundational Knowledge for Future Innovations."
Early bird rates end June 1st! ⏳
Register: https://ssr.org/events/2026-annual-meeting/
#ReproSci #ScienceTwitter
Join us in Indianapolis (July 19-22) as we explore "Back to the Future: Foundational Knowledge for Future Innovations."
Early bird rates end June 1st! ⏳
Register: https://ssr.org/events/2026-annual-meeting/
#ReproSci #ScienceTwitter
Join us for the Melbourne @reproducibilitea.org journal club happening today at 4pm AEST. This week, we discuss a recent preprint on replicating drosophila immunity studies, article linked below. Zoom link: unimelb.zoom.us/j/8289083982...
A retrospective analysis of 400 publications reveals patterns of irreproducibility across an entire life sciences research field
The ReproSci project retrospectively analyzed the reproducibility of 1006 claims from 400 papers published between 1959 and 2011 in the field of Drosophila immunity. This project attempts to provide a...
www.biorxiv.org
August 28, 2025 at 3:31 AM
Join us for the Melbourne @reproducibilitea.org journal club happening today at 4pm AEST. This week, we discuss a recent preprint on replicating drosophila immunity studies, article linked below. Zoom link: unimelb.zoom.us/j/8289083982...
The reprosci site is set up for any organism/field to do the same effort. Qed seems like it could be a great way to populate the major/minor claims, perhaps with a bit of crowdsourced wikipedia-like editing to ensure important nuance. 2/2
October 10, 2025 at 4:53 AM
The reprosci site is set up for any organism/field to do the same effort. Qed seems like it could be a great way to populate the major/minor claims, perhaps with a bit of crowdsourced wikipedia-like editing to ensure important nuance. 2/2
2/ The first article analyzes the reproducibility of 1006 claims from 400 papers published between 1959 and 2011. They found 61% were verified, only 7% were directly challenged (not reproducible), and 24% of claims remain unchallenged.
🔗 elifesciences.org/reviewed-pre...
🔗 elifesciences.org/reviewed-pre...
January 23, 2026 at 9:02 PM
2/ The first article analyzes the reproducibility of 1006 claims from 400 papers published between 1959 and 2011. They found 61% were verified, only 7% were directly challenged (not reproducible), and 24% of claims remain unchallenged.
🔗 elifesciences.org/reviewed-pre...
🔗 elifesciences.org/reviewed-pre...
I saw this loads in ReproSci, thankfully mostly in a consulting role, where authors volunteered their "null results" to "disprove a claim" when their experimental approach hadn't actually adressed the original claim...
In reality, they'd extrapolated on the claim & failed to advance with it.
3/n
In reality, they'd extrapolated on the claim & failed to advance with it.
3/n
July 23, 2025 at 9:50 PM
I saw this loads in ReproSci, thankfully mostly in a consulting role, where authors volunteered their "null results" to "disprove a claim" when their experimental approach hadn't actually adressed the original claim...
In reality, they'd extrapolated on the claim & failed to advance with it.
3/n
In reality, they'd extrapolated on the claim & failed to advance with it.
3/n
Been thinking on how to say this after the ReproSci fly immunity studies, and community comments...
To add to this issue, file drawer effects are treated almost as if they are de facto "the truth" when most people trained in molecular biology would never say that.
#Reproducibility #SciPub
1/n
To add to this issue, file drawer effects are treated almost as if they are de facto "the truth" when most people trained in molecular biology would never say that.
#Reproducibility #SciPub
1/n
I believe at this time we can afford more nuance and precision than this. Most null results are uninformative because most experiments are uninformative because we use NHST to replace the scientific process. We can't keep avoiding the root problem forever. Also the focus on efficiency is jarring.
Scientists overwhelmingly recognize the value of sharing null results, but rarely publish them in the research literature
go.nature.com/450KElr
go.nature.com/450KElr
July 23, 2025 at 9:50 PM
Been thinking on how to say this after the ReproSci fly immunity studies, and community comments...
To add to this issue, file drawer effects are treated almost as if they are de facto "the truth" when most people trained in molecular biology would never say that.
#Reproducibility #SciPub
1/n
To add to this issue, file drawer effects are treated almost as if they are de facto "the truth" when most people trained in molecular biology would never say that.
#Reproducibility #SciPub
1/n