Yes, this is indeed a Sézary cell, from a case of mycosis fungoides/Sézary Syndrome, showing the classic "cerebriform" nucleus!
#PathSky #HemePathSky #Sezary
#PathSky #HemePathSky #Sezary
November 19, 2024 at 6:59 PM
Yes, this is indeed a Sézary cell, from a case of mycosis fungoides/Sézary Syndrome, showing the classic "cerebriform" nucleus!
#PathSky #HemePathSky #Sezary
#PathSky #HemePathSky #Sezary
Insights on Mogamulizumab in Mycosis Fungoides and Sézary Syndrome - Yan Leyfman
@yleyfman.bsky.social
oncodaily.com/science/moga...
#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #Mogamulizumab #MycosisFungoides #SézarySyndrome
@yleyfman.bsky.social
oncodaily.com/science/moga...
#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #Mogamulizumab #MycosisFungoides #SézarySyndrome
Yan Leyfman: Insights on Mogamulizumab in Mycosis Fungoides and Sézary Syndrome - OncoDaily
Yan Leyfman: Insights on Mogamulizumab in Mycosis Fungoides and Sézary Syndrome / Alison J. Moskowitz, cancer, Melissa Pulitzer, Memorial Sloan Kettering
oncodaily.com
August 30, 2025 at 12:49 AM
Insights on Mogamulizumab in Mycosis Fungoides and Sézary Syndrome - Yan Leyfman
@yleyfman.bsky.social
oncodaily.com/science/moga...
#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #Mogamulizumab #MycosisFungoides #SézarySyndrome
@yleyfman.bsky.social
oncodaily.com/science/moga...
#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #Mogamulizumab #MycosisFungoides #SézarySyndrome
Sézary syndrome?
Do you agree or disagree?
Do you agree or disagree?
March 3, 2026 at 6:26 PM
Sézary syndrome?
Do you agree or disagree?
Do you agree or disagree?
So easy to forget that new therapies, as marvellous as they might be, can present with a myriad side effects. 6/12 of Pembrolizumab and I’m now thyrotoxic, with +/- hypophysitis. Rx by a second specialty service has commenced. I’m hopeful of symptom resolution. #Sèzary
December 13, 2024 at 10:31 AM
So easy to forget that new therapies, as marvellous as they might be, can present with a myriad side effects. 6/12 of Pembrolizumab and I’m now thyrotoxic, with +/- hypophysitis. Rx by a second specialty service has commenced. I’m hopeful of symptom resolution. #Sèzary
Sezary syndrome
February 16, 2025 at 4:54 PM
Sezary syndrome
Can bacterial infections make cancer cells resistant to treatment?
In Sézary Syndrome (SS), it turns out they can!
Want to know more? I will summarize some highlights from our study below.
doi.org/10.1182/bloo...
In Sézary Syndrome (SS), it turns out they can!
Want to know more? I will summarize some highlights from our study below.
doi.org/10.1182/bloo...
Staphylococcus aureus induces drug resistance in cancer T cells in Sézary syndrome
Enterotoxins from S aureus bacteria induce drug resistance in primary malignant T cells in SS.Targeting bacteria, their toxins, and downstream signaling pa
doi.org
November 19, 2024 at 5:44 PM
Can bacterial infections make cancer cells resistant to treatment?
In Sézary Syndrome (SS), it turns out they can!
Want to know more? I will summarize some highlights from our study below.
doi.org/10.1182/bloo...
In Sézary Syndrome (SS), it turns out they can!
Want to know more? I will summarize some highlights from our study below.
doi.org/10.1182/bloo...
Autocorrect changed sezary to sexact oops
January 23, 2026 at 12:19 AM
Autocorrect changed sezary to sexact oops
Anxiety Storytime:
So my 89 year old father, who has lymphoma (Sézary syndrome, if you're curious about the aggression), lives alone and is not pursuing chemo, JUST told me he's cut a large tree down with his chainsaw, and is now sawing it into burnable-size pieces.
So my 89 year old father, who has lymphoma (Sézary syndrome, if you're curious about the aggression), lives alone and is not pursuing chemo, JUST told me he's cut a large tree down with his chainsaw, and is now sawing it into burnable-size pieces.
December 20, 2024 at 7:09 PM
Anxiety Storytime:
So my 89 year old father, who has lymphoma (Sézary syndrome, if you're curious about the aggression), lives alone and is not pursuing chemo, JUST told me he's cut a large tree down with his chainsaw, and is now sawing it into burnable-size pieces.
So my 89 year old father, who has lymphoma (Sézary syndrome, if you're curious about the aggression), lives alone and is not pursuing chemo, JUST told me he's cut a large tree down with his chainsaw, and is now sawing it into burnable-size pieces.
First it came for my pituitary, then my thyroid and now… my lungs👇. #Pembrolizumab pneumonitis. Lymphoma (Sézary) under control however!
April 7, 2025 at 8:56 AM
First it came for my pituitary, then my thyroid and now… my lungs👇. #Pembrolizumab pneumonitis. Lymphoma (Sézary) under control however!
Sezary syndrome. Cerebriform nuclei
November 18, 2024 at 8:43 PM
Sezary syndrome. Cerebriform nuclei
Conversational Artificial Intelligence-Enabled Molecular Characterization of Sezary Syndrome Reveals Distinct Pathway-Level Alterations Compared with Non-Sezary Cutaneous T-Cell Lymphoma https://www.medrxiv.org/content/10.64898/2026.03.09.26347970v1
March 11, 2026 at 2:26 AM
Conversational Artificial Intelligence-Enabled Molecular Characterization of Sezary Syndrome Reveals Distinct Pathway-Level Alterations Compared with Non-Sezary Cutaneous T-Cell Lymphoma https://www.medrxiv.org/content/10.64898/2026.03.09.26347970v1
In case anyone wanted to read a little bit about what kind of cancer I have. I have the Sezary type.
It took 5 years from the time I saw the first spot on my skin to get a proper diagnosis. I have been in treatment since December 2022.
It took 5 years from the time I saw the first spot on my skin to get a proper diagnosis. I have been in treatment since December 2022.
March 12, 2026 at 5:17 PM
In case anyone wanted to read a little bit about what kind of cancer I have. I have the Sezary type.
It took 5 years from the time I saw the first spot on my skin to get a proper diagnosis. I have been in treatment since December 2022.
It took 5 years from the time I saw the first spot on my skin to get a proper diagnosis. I have been in treatment since December 2022.
My mom started on the oral cancer drug Targretin in April 2013 for her lymph, blood, and skin cancer (Sezary Syndrome). The cost was $11,000 a month.
The price kept increasing every 4-6 months.
By May 2015 the price had increased to $42,000 a month for the same dosage.
I still save the receipts.
The price kept increasing every 4-6 months.
By May 2015 the price had increased to $42,000 a month for the same dosage.
I still save the receipts.
May 27, 2025 at 3:41 PM
My mom started on the oral cancer drug Targretin in April 2013 for her lymph, blood, and skin cancer (Sezary Syndrome). The cost was $11,000 a month.
The price kept increasing every 4-6 months.
By May 2015 the price had increased to $42,000 a month for the same dosage.
I still save the receipts.
The price kept increasing every 4-6 months.
By May 2015 the price had increased to $42,000 a month for the same dosage.
I still save the receipts.
The impact of gene copy number alterations in circulating tumor cells in patients with Mycosis Fungoides/Sézary Syndrome are identified as prognostic markers in new research presented by Dr. Ahmad Kiwan #ASH24. ash.confex.com/ash/2024/web...
@yaleschoolofmed.bsky.social @oncoalert.bsky.social
@yaleschoolofmed.bsky.social @oncoalert.bsky.social
December 10, 2024 at 7:56 PM
The impact of gene copy number alterations in circulating tumor cells in patients with Mycosis Fungoides/Sézary Syndrome are identified as prognostic markers in new research presented by Dr. Ahmad Kiwan #ASH24. ash.confex.com/ash/2024/web...
@yaleschoolofmed.bsky.social @oncoalert.bsky.social
@yaleschoolofmed.bsky.social @oncoalert.bsky.social
I would bet on Sezary cell (and above all ask for clinical details)
November 18, 2024 at 10:05 PM
I would bet on Sezary cell (and above all ask for clinical details)
From #ASH24 oral: CTCL global QOL scores & pruritis improve in both responders & non-responders (non-responders just have a delayed improvement). No pts with Sezary had severe CTCL symptoms by week 81! PRO benefit in both SS & MF. #lymsm #MajorPROsASH
December 8, 2024 at 6:28 PM
From #ASH24 oral: CTCL global QOL scores & pruritis improve in both responders & non-responders (non-responders just have a delayed improvement). No pts with Sezary had severe CTCL symptoms by week 81! PRO benefit in both SS & MF. #lymsm #MajorPROsASH
#Pembrolizumab effective also for CTCL (Sézary Syndrome - in my case). Significant s/es however… hypophysitis, thyroiditis, pneumonitis. But, I live!
June 1, 2025 at 2:29 AM
#Pembrolizumab effective also for CTCL (Sézary Syndrome - in my case). Significant s/es however… hypophysitis, thyroiditis, pneumonitis. But, I live!
Real-world Use of Mogamulizumab Among Patients With Mycosis Fungoides and Sézary Syndrome Before and During #COVID19 in 🇺🇸
www.sciencedirect.com/science/arti...
www.clinicalmicrobiologyandinfection.com/article/S119...
#Casereport
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
www.clinicalmicrobiologyandinfection.com/article/S119...
#Casereport
www.sciencedirect.com/science/arti...
Real-world Use of Mogamulizumab Among Patients With Mycosis Fungoides and Sézary Syndrome Before and During COVID-19 in the United States
During the coronavirus disease 2019 (COVID-19) pandemic, professional organizations suggested extending dosing intervals for systemic cancer therapies…
www.sciencedirect.com
January 3, 2025 at 6:06 AM
Real-world Use of Mogamulizumab Among Patients With Mycosis Fungoides and Sézary Syndrome Before and During #COVID19 in 🇺🇸
www.sciencedirect.com/science/arti...
www.clinicalmicrobiologyandinfection.com/article/S119...
#Casereport
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
www.clinicalmicrobiologyandinfection.com/article/S119...
#Casereport
www.sciencedirect.com/science/arti...
The natural HLA-Peptidome of Sezary Syndrome: uncovering antigens for T cell-based immunotherapy
http://biorxiv.org/cgi/content/short/2024.12.25.630030v1
December 26, 2024 at 5:38 AM
The natural HLA-Peptidome of Sezary Syndrome: uncovering antigens for T cell-based immunotherapy
http://biorxiv.org/cgi/content/short/2024.12.25.630030v1
(BioRxiv All) The natural HLA-Peptidome of Sezary Syndrome: uncovering antigens for T cell-based immunotherapy: Sezary syndrome (SS) is a rare and aggressive form of cutaneous T-cell lymphoma, that has a poor prognosis, with a median overall survival time… http://dlvr.it/TH0nFk #BioRxiv #MassSpecRSS
December 26, 2024 at 4:03 AM
(BioRxiv All) The natural HLA-Peptidome of Sezary Syndrome: uncovering antigens for T cell-based immunotherapy: Sezary syndrome (SS) is a rare and aggressive form of cutaneous T-cell lymphoma, that has a poor prognosis, with a median overall survival time… http://dlvr.it/TH0nFk #BioRxiv #MassSpecRSS