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President Donald Trump has issued a series of aggressive statements on his Truth Social platform, accusing Democratic officials in Alaska of election fraud and demanding the removal of Senate candidate Mary Peltola from the ballot. Trump's claims stem from a New York Times investigation that linked Peltola's campaign and national Democratic operatives to efforts to recruit a candidate named Dan Sullivan for the Alaska Senate race. Trump alleged that Democrats 'illegally searched for, and recruited' Dan Sullivan to run against Republican Senator Dan Sullivan, claiming this was an attempt to 'defraud, confuse, and obfuscate the Election.' He further accused Peltola's campaign of making 'false statements under oath in Federal Court,' which he labeled as perjury, and demanded that she face 'very serious consequences.' Trump's posts included a link to the Times report with the all-caps declaration 'CROOKED ELECTION IN ALASKA!' and reiterated his demand that Peltola be barred from the race, stating, 'She shouldn't be allowed to run, and neither should the FAKE Dan Sullivan!' The Alaska Supreme Court has previously allowed the second Sullivan to remain on the ballot, despite Trump's DOJ filing a separate lawsuit over the Alaska Senate race. Trump's accusations appear to be based on a misunderstanding or misrepresentation of the situation, as Peltola's campaign and national Democrats have denied involvement in recruiting another candidate with the same name. The president's rhetoric has intensified political tensions in the lead-up to the 2026 midterms, with his MAGA allies facing a critical Senate race in Alaska. Trump's claims of election fraud, while not new, have become increasingly prominent in his public statements, often targeting Democratic opponents with unsubstantiated allegations. The situation highlights ongoing partisan disputes over election integrity, with Trump's base increasingly receptive to his claims of widespread fraud, even when lacking concrete evidence. The Alaska Senate race has become a focal point for these tensions, with Trump's intervention adding a new layer of complexity to the political landscape. The president's demands for legal action against Peltola and her campaign have drawn criticism from legal experts who note that the allegations lack the necessary evidence to support such claims. As the midterms approach, Trump's focus on alleged election fraud continues to shape the political narrative, with significant implications for both the Alaska race and the broader national political climate.

Activating PIK3CA mutations occur in cancer and also non-malignant overgrowth disorders, in which marked lineage-selectivity of pathology is characteristic. Yet the basis of such context-dependent eff...

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Weil, Gotshal & Manges plans to wind down ​its operations, its leadership told partners on Wednesday, ‌capping a dizzying downfall for the nearly century-old law firm after it failed to stem an exodus of partners.

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Aneuploidy is frequent in human pre-implantation embryos and a leading cause of early pregnancy loss, yet is rarely observed at birth, implying robust embryonic surveillance. Here we define how this surveillance operates after implantation using an integrated, three-lineage stem cell–derived embryo model that recapitulates the epiblast (EPI), visceral endoderm (VE), and extraembryonic ectoderm (ExE). Seeding of aneuploid cells into each lineage independently reveals lineage-specific fates: aneuploid cells are selectively depleted from EPI and VE but persist within ExE. Live imaging captures their removal by apoptosis or physical extrusion. Single-cell RNA sequencing shows p53 activation and Myc repression in aneuploid cells, and pathway perturbations modulate their clearance, confirming causality. Together, these findings demonstrate a post-implantation, lineage-restricted quality-control program that eliminates aneuploid cells from the embryo proper while permitting extraembryonic tol