#SimulAdren
#SimulAdren has been released in version 1.1. This cross-platform simulator of the corticotropic feedback loop (hypothalamus-pituitary-adrenal or #HPA axis) is based on the #CyberUnits Bricks class library.

doi.org/10.5281/zeno...
doi.org/10.5281/zeno...
simuladren.sf.net
December 13, 2025 at 9:34 PM
#SimulAdren underwent a major upgrade. Version 2.0 introduces significant new features, e.g., support for different models, initial conditions, first-order delay kinetics (ASIA elements), and model continuation.

simuladren.sourceforge.io
doi.org/10.5281/zeno...
doi.org/10.5281/zeno...
March 24, 2026 at 11:40 PM
#Simuladren, a simulator for the #HPA axis based on #CyberUnits Bricks, has been updated to version 1.2. This upgrade introduces support for XML files according to #MIASE and #MIRIAM guidelines and high-res displays on Windows.

simuladren.sourceforge.io
doi.org/10.5281/zeno...
January 27, 2026 at 10:57 PM
#SimulAdren has been upgraded to version 2.1, introducing a cosinor-based model for circadian #CRH secretion, speed improvements and bug fixes.

#HPA axis, #adrenal homeostasis, #corticotropic feedback control

simuladren.sourceforge.io
doi.org/10.5281/zeno...
doi.org/10.5281/zeno...
August 29, 2026 at 9:36 PM
#SimulAdren, the open dynamic simulator for the #HPA-axis, i. e. the #hypothalamus-pituitary-adrenal feedback control, has been released in version 2.0.1. This is a recommended update that fixes several bugs.

simuladren.sourceforge.io
doi.org/10.5281/zeno...
doi.org/10.5281/zeno...
May 24, 2026 at 8:46 PM
#SimulAdren, based on #CyberUnits Bricks, has been upgraded to version 1.3 (Green Lizard). This version introduces functionality to save plots and the block diagram of the information processing structure as graphics files.

simuladren.sourceforge.io
doi.org/10.5281/zeno...
doi.org/10.5281/zeno...
March 13, 2026 at 11:34 PM
#SimulAdren is a simulation program for the #hypothalamus - #pituitary - #adrenal feedback control, an essential physiological motif. It is written in #Object_Pascal and helps to understand life-threatening diseases.
#Simuladren, a simulator for the #HPA axis based on #CyberUnits Bricks, has been updated to version 1.2. This upgrade introduces support for XML files according to #MIASE and #MIRIAM guidelines and high-res displays on Windows.

simuladren.sourceforge.io
doi.org/10.5281/zeno...
January 27, 2026 at 11:07 PM