The #SleepWakeCycle is regulated by the #CerebralAdenosinergicSystem. During #AcuteSleepDeprivation, #CerebralA1AdenosineReceptor availability increases, contributing to #CognitiveImpairment. This study used #Polysomnography, #PET, and cognitive testing to examine #ChronicSleepDeprivation.
Chronic sleep loss and A1 adenosine receptors in the human brain
AbstractStudy Objectives. The cerebral adenosinergic system is involved in sleep–wake regulation and presumably represents a neuro-molecular correlate of h
academic.oup.com
July 30, 2026 at 12:36 PM
The #SleepWakeCycle is regulated by the #CerebralAdenosinergicSystem. During #AcuteSleepDeprivation, #CerebralA1AdenosineReceptor availability increases, contributing to #CognitiveImpairment. This study used #Polysomnography, #PET, and cognitive testing to examine #ChronicSleepDeprivation.
#Locuscoerleus (LC) neurons are important to the #sleepwakecycle and #cognitivehealth. In sleep disorders #hypoxia can hinder the strength of #LCneurons, impacting cognitive health. Using #7Timaging on #olderadults, these authors demonstrate that #hypoxia has a negative effect on #LCneuronintegrity.
High obstructive sleep apnea hypoxic burden associates with reduced locus coeruleus structural integrity on 7T MRI in older adults
Statement of Significance The impact of obstructive sleep apnea on brainstem structures has not previously been evaluated in human subjects despite the imp
academic.oup.com
May 28, 2026 at 12:59 PM
#Locuscoerleus (LC) neurons are important to the #sleepwakecycle and #cognitivehealth. In sleep disorders #hypoxia can hinder the strength of #LCneurons, impacting cognitive health. Using #7Timaging on #olderadults, these authors demonstrate that #hypoxia has a negative effect on #LCneuronintegrity.
Accelerometer-derived #SleepWakeCycle metrics moderately improved dementia risk prediction in large cohort studies, performing similarly to genetic and plasma biomarkers. ja.ma/3RejtQY
May 19, 2026 at 2:00 PM
Accelerometer-derived #SleepWakeCycle metrics moderately improved dementia risk prediction in large cohort studies, performing similarly to genetic and plasma biomarkers. ja.ma/3RejtQY
A new study found that adults who stay up late and are active at #night are more likely to have poor #CardiovascularHealth scores than those with more typical #sleep -wake schedules.
#Chronotype #SleepWakeCycle #CardiovascularDisease #CardiovascularRisk
#Chronotype #SleepWakeCycle #CardiovascularDisease #CardiovascularRisk
Being a night owl may increase your cardiovascular risk – BioNews Central
A new study found that adults who stay up late and are active at night were more likely to have poor cardiovascular health scores than people with more typical sleep-wake timing. ...
sbee.link
January 28, 2026 at 8:14 PM
A new study found that adults who stay up late and are active at #night are more likely to have poor #CardiovascularHealth scores than those with more typical #sleep -wake schedules.
#Chronotype #SleepWakeCycle #CardiovascularDisease #CardiovascularRisk
#Chronotype #SleepWakeCycle #CardiovascularDisease #CardiovascularRisk
An irregular ##SleepWakeCycle is associated with an increased risk of major ##CardiovascularEvents, such as ##HeartAttack and ##stroke, even among individuals who get the recommended amount of ##sleep each night.
##IrregularSleep ##CardiovascularDisease ##CardiovascularRisk
##IrregularSleep ##CardiovascularDisease ##CardiovascularRisk
Irregular sleep-wake cycle linked to heightened risk of major cardiovascular events – BioNews Central
An irregular sleep-wake cycle is associated with a heightened risk of major cardiovascular events, such as heart attack and stroke, even among individuals who get the recommended amount of sleep each night. ...
sbee.link
November 27, 2024 at 2:06 PM
An irregular ##SleepWakeCycle is associated with an increased risk of major ##CardiovascularEvents, such as ##HeartAttack and ##stroke, even among individuals who get the recommended amount of ##sleep each night.
##IrregularSleep ##CardiovascularDisease ##CardiovascularRisk
##IrregularSleep ##CardiovascularDisease ##CardiovascularRisk