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Amid collapse of global pollution treaty, scientists highlight environmental factors causing fertility crisis

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Researchers in China found multiple types of microplastics in human semen and urine, with exposure to PTFE significantly linked to reduced sperm quality, highlighting potential reproductive health ris...

(Beyond Pesticides, July 14, 2022) A study published in Toxicology and Applied Pharmacology finds prepubescent exposure to endocrine-disrupting chemicals (EDCs), including pesticides, impairs male reproduction through the interruption of testicular homeostasis and development of reproductive Leydig cells. Endocrine disruptors are xenobiotic (i.e., chemical substances like toxic pesticides foreign to an organism or ecosystem). Many reports demonstrate that exposure to endocrine-disrupting chemicals can adversely affect human, animal—and thus environmental—health by altering the natural hormones in the body responsible for conventional reproductive, physical, and mental development. Scientists and health officials already associate pesticide exposure with a decrease in male fertility, including reduced sperm count, quality, and abnormal sperm development. The presence of pesticides in the body has implications for human health, especially during vulnerable life stages, such as childhood, puberty, pregnancy, and old age. Therefore, it is essential to understand how exposure to toxic chemicals in the environment affects future reproductive success and health. The researchers note, “Recent studies revealed that exposures to EDCs during so-called critical windows of susceptibility (prenatal, prepubertal, pubertal, and aging periods) could disrupt healthy patterns of testes development and homeostasis, which can be demonstrated as an impaired testicular function later in life. However, much more work is needed to understand better the cellular […]

Exclusive: Researchers warn of ‘major crisis in male reproductive health’ partly driven by obesity and diabetes

Tell EPA and Congress that pesticide use cannot continue without findings of no endocrine disruption. Demand that EPA test for and act on endocrine disruptors as required by law. #pesticides #menshealth #spermcount #fertility #globalissues #endocrine #organics #takeaction

(Beyond Pesticides, November 18, 2022) A new meta-analysis, from researchers at Mount Sinai Medical Center, Hebrew University of Jerusalem, and the University of Copenhagen, among others, finds that the drop in global sperm count is accelerating and the problem has become global. The study shows that sperm count (until this study measured largely in North America, Europe, and Australia) has dropped by 51.6% from 1973 through 2018, and that the rate of decline is gaining speed worldwide.  A primary culprit, among a plexus of factors, is widespread exposure to toxic chemicals, including pesticides, in the environment. Beyond the implications for individuals and families, this global decline in sperm counts has the potential for population-level impacts and, according to Dr. Shanna Swan, an expert environmental–reproductive epidemiologist, could mean that “in the coming decades, large swaths of the global population of men could be subfertile or infertile.” Beyond Pesticides has long highlighted the relationship between reproductive anomalies and toxic pesticides, particularly the role of endocrine-disrupting (ED) compounds. Most recently, we covered a meta-study on pesticides and fertility that “finds exposure associated with lower semen quality, DNA fragmentation, and chromosomal abnormalities.” The new study is covered in Environmental Health News (EHN). From 1972 […]