Novo’s CagriSema shot was shown to be less effective than rival Lilly’s tirzepatide
Novo Nordisk’s New Weight Loss Shot Loses To Rival Eli Lilly In Clinical Trial—Stock Plummets
Novo’s CagriSema shot was shown to be less effective than rival Lilly’s tirzepatide
www.forbes.com
February 23, 2026 at 2:30 PM
Novo’s CagriSema shot was shown to be less effective than rival Lilly’s tirzepatide
Our randomized, placebo-controlled trial of tirzepatide (Zepbound) for #LongCovid has already enrolled 500 participants of 1000 planned in less than 2 weeks!
longcovid.scripps.edu/locitt-t/
longcovid.scripps.edu/locitt-t/
LoCITT-T - Long COVID Treatment Trial
The Long COVID Treatment Trial-Tirzepatide (LoCITT-T) is investigating the efficacy of repurposing this drug to treat Long COVID.
longcovid.scripps.edu
November 13, 2025 at 3:21 PM
Our randomized, placebo-controlled trial of tirzepatide (Zepbound) for #LongCovid has already enrolled 500 participants of 1000 planned in less than 2 weeks!
longcovid.scripps.edu/locitt-t/
longcovid.scripps.edu/locitt-t/
why is the tirzepatide.... down there...
August 9, 2026 at 1:41 AM
why is the tirzepatide.... down there...
Another GLP-1 drug success. Tirzepatide in heart failure with preserved ejection fraction (HFpEF) with longer term follow-up than 2 previous trials with semaglutide
nejm.org/doi/full/10....
in people with BMI >30; no data yet for HFpEF in people without obesity
nejm.org/doi/full/10....
in people with BMI >30; no data yet for HFpEF in people without obesity
Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity | NEJM
Obesity increases the risk of heart failure with preserved ejection fraction. Tirzepatide, a long-acting agonist of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor...
nejm.org
November 16, 2024 at 3:12 PM
Another GLP-1 drug success. Tirzepatide in heart failure with preserved ejection fraction (HFpEF) with longer term follow-up than 2 previous trials with semaglutide
nejm.org/doi/full/10....
in people with BMI >30; no data yet for HFpEF in people without obesity
nejm.org/doi/full/10....
in people with BMI >30; no data yet for HFpEF in people without obesity
A 3-year study of tirzepatide in participants with obesity and prediabetes showed substantial and sustained weight reduction and decreased risk of progression to diabetes with tirzepatide, as compared with placebo. Full SURMOUNT-1 trial results: nej.md/48VdDZp
#endosky #medsky
#endosky #medsky
Tirzepatide for Obesity Treatment and Diabetes Prevention | NEJM
Obesity is chronic disease and causal precursor to myriad other conditions, including
type 2 diabetes. In an earlier analysis of the SURMOUNT-1 trial, tirzepatide was shown
to provide substantial a...
nej.md
December 7, 2024 at 3:15 PM
A 3-year study of tirzepatide in participants with obesity and prediabetes showed substantial and sustained weight reduction and decreased risk of progression to diabetes with tirzepatide, as compared with placebo. Full SURMOUNT-1 trial results: nej.md/48VdDZp
#endosky #medsky
#endosky #medsky
Tirzepatide and levothyroxine have been life changing for me so if someone else tells me they really need some hormone or other I’m inclined to believe them
September 28, 2026 at 2:11 AM
Tirzepatide and levothyroxine have been life changing for me so if someone else tells me they really need some hormone or other I’m inclined to believe them
New 3-year data presented today for Tirzepatide (Mounjaro, Zepbound) indicates 3 different patterns of weight loss
www.eurekalert.org/news-release...
www.eurekalert.org/news-release...
April 11, 2025 at 10:36 PM
New 3-year data presented today for Tirzepatide (Mounjaro, Zepbound) indicates 3 different patterns of weight loss
www.eurekalert.org/news-release...
www.eurekalert.org/news-release...
This month, a phase 3 trial of tirzepatide (a GLP-1 drug) found that it reduced the chances of developing type 2 diabetes by around 90% (!), among people with obesity and pre-diabetes.
That's a reduction if I ever saw one.
www.nejm.org/doi/full/10....
That's a reduction if I ever saw one.
www.nejm.org/doi/full/10....
November 26, 2024 at 12:11 PM
This month, a phase 3 trial of tirzepatide (a GLP-1 drug) found that it reduced the chances of developing type 2 diabetes by around 90% (!), among people with obesity and pre-diabetes.
That's a reduction if I ever saw one.
www.nejm.org/doi/full/10....
That's a reduction if I ever saw one.
www.nejm.org/doi/full/10....
The GLP-1 drugs (Tirzepatide) got another big boost today for marked reduction of sleep apnea in 2 randomized trials
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Tirzepatide for the Treatment of Obstructive Sleep Apnea and Obesity | NEJM
Obstructive sleep apnea is characterized by disordered breathing during sleep and
is associated with major cardiovascular complications; excess adiposity is an etiologic
risk factor. Tirzepatide ma...
www.nejm.org
June 21, 2024 at 9:25 PM
The GLP-1 drugs (Tirzepatide) got another big boost today for marked reduction of sleep apnea in 2 randomized trials
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
In he first report, notable differences between dual receptor agonist tirzepatide vs semaglutide
December 27, 2024 at 3:15 PM
In he first report, notable differences between dual receptor agonist tirzepatide vs semaglutide
I wish I could say it was all will power but it was a 5 mg shot once a week of tirzepatide from a compounding lab my doctor recommended and a very regimented calorie, simple sugar and carb restrictive diet that I stick to along with regular light to moderate exercise.
September 26, 2026 at 3:15 PM
I wish I could say it was all will power but it was a 5 mg shot once a week of tirzepatide from a compounding lab my doctor recommended and a very regimented calorie, simple sugar and carb restrictive diet that I stick to along with regular light to moderate exercise.
tirzepatide when doctors prescribe it for weight loss AND now moderate-to-severe obstructive sleep apnea. Mounjaro is the name of the medication when it’s used to treat diabetes. Both Zepbound and Mounjaro are brand names for the generic drug, tirzepatide. In other words, they both share the same
December 21, 2024 at 5:02 PM
tirzepatide when doctors prescribe it for weight loss AND now moderate-to-severe obstructive sleep apnea. Mounjaro is the name of the medication when it’s used to treat diabetes. Both Zepbound and Mounjaro are brand names for the generic drug, tirzepatide. In other words, they both share the same
Just published @nejm.org
A randomized trial of Semaglutide (Ozempic) vs Tirzepatide (Mounjaro, Zepbound) at max doses demonstrates superiority of the latter for weight loss
www.nejm.org/doi/full/10.1056/NEJMoa2416394
A randomized trial of Semaglutide (Ozempic) vs Tirzepatide (Mounjaro, Zepbound) at max doses demonstrates superiority of the latter for weight loss
www.nejm.org/doi/full/10.1056/NEJMoa2416394
May 11, 2025 at 10:02 PM
Just published @nejm.org
A randomized trial of Semaglutide (Ozempic) vs Tirzepatide (Mounjaro, Zepbound) at max doses demonstrates superiority of the latter for weight loss
www.nejm.org/doi/full/10.1056/NEJMoa2416394
A randomized trial of Semaglutide (Ozempic) vs Tirzepatide (Mounjaro, Zepbound) at max doses demonstrates superiority of the latter for weight loss
www.nejm.org/doi/full/10.1056/NEJMoa2416394
Participants are now enrolling in our #longCovid randomized, controlled trial of tirzepatide. The largest trial to test a treatment for this condition. Home-based—no sites. In today's @sandiegouniontribune.com
www.sandiegouniontribune.com/2025/11/01/c...
www.sandiegouniontribune.com/2025/11/01/c...
November 1, 2025 at 2:16 PM
Participants are now enrolling in our #longCovid randomized, controlled trial of tirzepatide. The largest trial to test a treatment for this condition. Home-based—no sites. In today's @sandiegouniontribune.com
www.sandiegouniontribune.com/2025/11/01/c...
www.sandiegouniontribune.com/2025/11/01/c...
Tirzepatide accidentally saved my life when no one was taking my long covid seriously or even understood how badly it was messing me up. I truly hope they find some solid evidence it can help others, too.
We've just launched the first large, site-less (home, direct to participant) randomized trial for treatment of #LongCovid, testing tirzepatide (a GLP-1 drug) vs placebo. Please help spread the word
www.scripps.edu/news-and-eve...
www.scripps.edu/news-and-eve...
Scripps Research scientists launch new digital clinical trial to test repurposed drug for long COVID symptom relief
www.scripps.edu
November 1, 2025 at 11:39 AM
Tirzepatide accidentally saved my life when no one was taking my long covid seriously or even understood how badly it was messing me up. I truly hope they find some solid evidence it can help others, too.
In a randomized trial of tirzepatide (Zepbound, Mounjaro) vs placebo, brain activation by high fat and high sugar foods was decreased @naturemedicine.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
June 24, 2025 at 12:37 PM
In a randomized trial of tirzepatide (Zepbound, Mounjaro) vs placebo, brain activation by high fat and high sugar foods was decreased @naturemedicine.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Why does Zepbound (tirzepatide) lead to more weight loss than Ozempic (semaglutide)?
The dual receptor (GLP-1+ GIP) has more pronounced effects in the brain
www.cell.com/cell-metabol...
The dual receptor (GLP-1+ GIP) has more pronounced effects in the brain
www.cell.com/cell-metabol...
August 13, 2025 at 3:04 PM
Why does Zepbound (tirzepatide) lead to more weight loss than Ozempic (semaglutide)?
The dual receptor (GLP-1+ GIP) has more pronounced effects in the brain
www.cell.com/cell-metabol...
The dual receptor (GLP-1+ GIP) has more pronounced effects in the brain
www.cell.com/cell-metabol...
We've just launched the first large, site-less (home, direct to participant) randomized trial for treatment of #LongCovid, testing tirzepatide (a GLP-1 drug) vs placebo. Please help spread the word
www.scripps.edu/news-and-eve...
www.scripps.edu/news-and-eve...
Scripps Research scientists launch new digital clinical trial to test repurposed drug for long COVID symptom relief
www.scripps.edu
October 31, 2025 at 5:07 PM
We've just launched the first large, site-less (home, direct to participant) randomized trial for treatment of #LongCovid, testing tirzepatide (a GLP-1 drug) vs placebo. Please help spread the word
www.scripps.edu/news-and-eve...
www.scripps.edu/news-and-eve...
More than 2 decades since GLP-1 drugs were introduced, we still don't know why people with diabetes lose about half as much weight as those without diabetes at the same dose
nature.com/articles/s41...
nature.com/articles/s41...
Effects of tirzepatide on weight management in patients with and without diabetes: a systematic review and meta-analysis - International Journal of Obesity
International Journal of Obesity - Effects of tirzepatide on weight management in patients with and without diabetes: a systematic review and meta-analysis
nature.com
September 28, 2025 at 2:45 PM
More than 2 decades since GLP-1 drugs were introduced, we still don't know why people with diabetes lose about half as much weight as those without diabetes at the same dose
nature.com/articles/s41...
nature.com/articles/s41...
I was on tirzepatide for 8 months, and lost over 60 pounds. I also quit smoking. Exceptional craving control!
March 12, 2025 at 5:43 PM
I was on tirzepatide for 8 months, and lost over 60 pounds. I also quit smoking. Exceptional craving control!
3 weeks after I started on tirzepatide I started sleeping for the first time since I got covid in March 2020
bsky.app/profile/most...
bsky.app/profile/most...
This got surfaced again and I just wanted to post an update now that I have full data from 2024, and I just have to say: sleep is pretty neat. I'm a big fan!
(lol you can see my sleep spiral in Sept when I got the 3D printer & started staying up to continue prints oh no. I finally recovered!)
(lol you can see my sleep spiral in Sept when I got the 3D printer & started staying up to continue prints oh no. I finally recovered!)
August 18, 2026 at 12:13 AM
3 weeks after I started on tirzepatide I started sleeping for the first time since I got covid in March 2020
bsky.app/profile/most...
bsky.app/profile/most...