August 7, 2026 at 6:07 PM
I will miss younger Amelia.
bsky.app/profile/tnsb...
bsky.app/profile/tnsb...
July 15, 2026 at 6:51 PM
I will miss younger Amelia.
bsky.app/profile/tnsb...
bsky.app/profile/tnsb...
🚨New pub alert!🚨 Now available open-access in @hcr-journal.bsky.social, I show how endorsements of entertainment media from ingroup members, particularly inpartisans, affect exposure intentions, with differential effects across racial lines. #PolComm #PoliSci #Politics #MediaStudies 🧵
January 21, 2026 at 6:46 PM
🚨New pub alert!🚨 Now available open-access in @hcr-journal.bsky.social, I show how endorsements of entertainment media from ingroup members, particularly inpartisans, affect exposure intentions, with differential effects across racial lines. #PolComm #PoliSci #Politics #MediaStudies 🧵
Forthcoming at @hcr-journal.bsky.social: "A Show for Us: How Racial and Partisan Cues About Television Audiences Affect Exposure Intentions"! More to follow once the final version is published, but just glad this will be out in the world soon! #PolComm #PoliSci #Politics #MediaStudies
December 16, 2025 at 4:44 PM
Forthcoming at @hcr-journal.bsky.social: "A Show for Us: How Racial and Partisan Cues About Television Audiences Affect Exposure Intentions"! More to follow once the final version is published, but just glad this will be out in the world soon! #PolComm #PoliSci #Politics #MediaStudies
6/8 But hooks alone aren't enough ⚡. TnsB's beta-barrel domain must physically dock onto TnsC and grab the target DNA — triggering an allosteric relay that orders disordered domains, remodels the catalytic site by ~11 Å, and switches TnsB on for DNA integration. No target = no chemistry.
May 21, 2026 at 9:17 PM
6/8 But hooks alone aren't enough ⚡. TnsB's beta-barrel domain must physically dock onto TnsC and grab the target DNA — triggering an allosteric relay that orders disordered domains, remodels the catalytic site by ~11 Å, and switches TnsB on for DNA integration. No target = no chemistry.
Der Sumpf ist so TIEF, das kann sich ein Mensch nicht VORSTELLEN.
Die Qual der Kinder, das ist nicht zu ertragen. Wenn der Mainstream lauthals schweigt, weiß man wer die Veröffentlichung will oder nicht...
www.youtube.com/watch?v=tNSB...
Die Qual der Kinder, das ist nicht zu ertragen. Wenn der Mainstream lauthals schweigt, weiß man wer die Veröffentlichung will oder nicht...
www.youtube.com/watch?v=tNSB...
Epstein und die Babies | Winter-Files
YouTube video by Achim Winter
www.youtube.com
February 27, 2026 at 12:50 AM
Der Sumpf ist so TIEF, das kann sich ein Mensch nicht VORSTELLEN.
Die Qual der Kinder, das ist nicht zu ertragen. Wenn der Mainstream lauthals schweigt, weiß man wer die Veröffentlichung will oder nicht...
www.youtube.com/watch?v=tNSB...
Die Qual der Kinder, das ist nicht zu ertragen. Wenn der Mainstream lauthals schweigt, weiß man wer die Veröffentlichung will oder nicht...
www.youtube.com/watch?v=tNSB...
Lookin’ good 😎 Think I’ll be poppin beans next weekend in prep for this years outdoor run. A few Canuk/TNSB in the mix. Stay elevated ✌🏻
April 27, 2025 at 1:56 PM
Lookin’ good 😎 Think I’ll be poppin beans next weekend in prep for this years outdoor run. A few Canuk/TNSB in the mix. Stay elevated ✌🏻
We used SeqHub's CoSearch to explore CRISPR-associated transposon (CAST) systems and found interesting patterns. By searching for TnsB + Cas12 together (Liu et al., 2025), we compared genomic context and architecture across organisms, making it easier to reason about CAST subtypes.
February 6, 2026 at 3:09 PM
We used SeqHub's CoSearch to explore CRISPR-associated transposon (CAST) systems and found interesting patterns. By searching for TnsB + Cas12 together (Liu et al., 2025), we compared genomic context and architecture across organisms, making it easier to reason about CAST subtypes.
February 9, 2025 at 6:51 PM
February 9, 2025 at 6:50 PM
bsky.app/profile/tnsb... Adding the ep opening as another example!
January 21, 2025 at 1:18 PM
bsky.app/profile/tnsb... Adding the ep opening as another example!
or tnsb
October 3, 2024 at 4:43 PM
or tnsb
fanfancy+ with GiGO福岡天神
https://tempo.gendagigo.jp/tnsb/fanfancyplus-tenjin/
tempo.gendagigo.jp
December 18, 2024 at 3:01 PM
Parts 1-4/4 — EFTA01151227.jpg
#epsteinweb #efta01151227
https://epsteinweb.org
Available in the iOS app store now!
https://apps.apple.com/us/app/epstein-web/id6758880661
#epsteinweb #efta01151227
https://epsteinweb.org
Available in the iOS app store now!
https://apps.apple.com/us/app/epstein-web/id6758880661
May 12, 2026 at 5:30 AM
Parts 1-4/4 — EFTA01151227.jpg
#epsteinweb #efta01151227
https://epsteinweb.org
Available in the iOS app store now!
https://apps.apple.com/us/app/epstein-web/id6758880661
#epsteinweb #efta01151227
https://epsteinweb.org
Available in the iOS app store now!
https://apps.apple.com/us/app/epstein-web/id6758880661
Parts 1-4/4 — EFTA01151162.jpg
#epsteinweb #efta01151162
https://epsteinweb.org
Available in the iOS app store now!
https://apps.apple.com/us/app/epstein-web/id6758880661
#epsteinweb #efta01151162
https://epsteinweb.org
Available in the iOS app store now!
https://apps.apple.com/us/app/epstein-web/id6758880661
May 12, 2026 at 5:25 AM
Parts 1-4/4 — EFTA01151162.jpg
#epsteinweb #efta01151162
https://epsteinweb.org
Available in the iOS app store now!
https://apps.apple.com/us/app/epstein-web/id6758880661
#epsteinweb #efta01151162
https://epsteinweb.org
Available in the iOS app store now!
https://apps.apple.com/us/app/epstein-web/id6758880661
7/10 We combined the evolved TnsB w/ other PACE-evolved and rationally engineered CAST components (tinyurl.com/PseQCas) to yield evoCAST, a platform optimized for human-cell integration activity.
Structure-guided engineering of type I-F CASTs for targeted gene insertion in human cells
Conventional genome editing tools rely on DNA double-strand breaks (DSBs) and host recombination proteins to achieve large insertions, resulting in a heterogeneous mixture of undesirable editing outco...
tinyurl.com
May 15, 2025 at 10:49 PM
7/10 We combined the evolved TnsB w/ other PACE-evolved and rationally engineered CAST components (tinyurl.com/PseQCas) to yield evoCAST, a platform optimized for human-cell integration activity.
6/10 Critically, the evolved TnsB did not require co-delivery of ClpX, a CAST accessory protein we previously identified that is highly cytotoxic in human cells 🤢🤢🤢
May 15, 2025 at 10:49 PM
6/10 Critically, the evolved TnsB did not require co-delivery of ClpX, a CAST accessory protein we previously identified that is highly cytotoxic in human cells 🤢🤢🤢
5/10 After performing hundreds of evolutionary generations in PACE, we generated an evolved variant of the CAST transposase protein TnsB with ten (!!) activity-enhancing mutations enabling >200-fold improved integration activity in human cells.
May 15, 2025 at 10:49 PM
5/10 After performing hundreds of evolutionary generations in PACE, we generated an evolved variant of the CAST transposase protein TnsB with ten (!!) activity-enhancing mutations enabling >200-fold improved integration activity in human cells.
April 2, 2025 at 12:29 AM
March 30, 2025 at 4:45 AM
Following PASTs, we searched telomeric transposons by clustering and mapping the locations and orientations of DDE family transposases in Streptomyces. This analysis identified two groups of telomeric transposons: Tn7-like and the other containing only conserved tnsB and tnsC.
March 27, 2025 at 6:08 PM
Following PASTs, we searched telomeric transposons by clustering and mapping the locations and orientations of DDE family transposases in Streptomyces. This analysis identified two groups of telomeric transposons: Tn7-like and the other containing only conserved tnsB and tnsC.