1/ Electron microscopy can be helpful in the diagnosis of cryoglobulinemic glomerulonephritis.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
September 9, 2025 at 1:03 PM
1/ Electron microscopy can be helpful in the diagnosis of cryoglobulinemic glomerulonephritis.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
1/ This allograft biopsy shows the characteristic features of adenovirus infection.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
March 10, 2026 at 1:01 PM
1/ This allograft biopsy shows the characteristic features of adenovirus infection.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
Cholesterol emboli involving the kidney may manifest clinically as acute kidney injury, hematuria, proteinuria (both non-nephrotic and nephrotic range), and even new onset hypertension.
#TeachingPoints #kidneypath #renal #pathology #nephx #pathx
#TeachingPoints #kidneypath #renal #pathology #nephx #pathx
October 14, 2025 at 1:02 PM
Cholesterol emboli involving the kidney may manifest clinically as acute kidney injury, hematuria, proteinuria (both non-nephrotic and nephrotic range), and even new onset hypertension.
#TeachingPoints #kidneypath #renal #pathology #nephx #pathx
#TeachingPoints #kidneypath #renal #pathology #nephx #pathx
1/ The arrow in this image points to hyperplasia of the juxtaglomerular apparatus (JGA), which was seen diffusely in this biopsy.
#TeachingPoints #kidneypath #renal #pathology #pathsky
#TeachingPoints #kidneypath #renal #pathology #pathsky
March 18, 2025 at 1:05 PM
1/ The arrow in this image points to hyperplasia of the juxtaglomerular apparatus (JGA), which was seen diffusely in this biopsy.
#TeachingPoints #kidneypath #renal #pathology #pathsky
#TeachingPoints #kidneypath #renal #pathology #pathsky
One of the many patterns of tubular atrophy in the kidney is the aptly named “thyroidization” pattern because of its resemblance to normal thyroid gland follicles.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
May 27, 2026 at 1:02 PM
One of the many patterns of tubular atrophy in the kidney is the aptly named “thyroidization” pattern because of its resemblance to normal thyroid gland follicles.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
Immunotactoid glomerulopathy is one of many glomerular diseases characterized by organized deposits.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
April 7, 2026 at 1:17 PM
Immunotactoid glomerulopathy is one of many glomerular diseases characterized by organized deposits.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
(1/3) Paying close attention to morphologic detail can sometimes suggest etiologic clues in cases of severe chronic renal injury. The glomerulus in this image, for example, shows near complete global glomerulosclerosis.
#TeachingPoints #kidneypath #nephsky #pathsky #renal
#TeachingPoints #kidneypath #nephsky #pathsky #renal
October 28, 2025 at 1:02 PM
(1/3) Paying close attention to morphologic detail can sometimes suggest etiologic clues in cases of severe chronic renal injury. The glomerulus in this image, for example, shows near complete global glomerulosclerosis.
#TeachingPoints #kidneypath #nephsky #pathsky #renal
#TeachingPoints #kidneypath #nephsky #pathsky #renal
1/ This kidney biopsy is from an elderly adult patient with acute renal failure and a history of non-steroidal anti-inflammatory medication (NSAID) use.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
December 30, 2025 at 2:02 PM
1/ This kidney biopsy is from an elderly adult patient with acute renal failure and a history of non-steroidal anti-inflammatory medication (NSAID) use.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
The differential diagnosis for interstitial hemorrhage includes hemorrhagic necrosis in the setting of renal artery thrombosis, infection (e.g. herpes simplex virus, adenovirus, hantavirus, Rickettsia),...(1/2)
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
February 10, 2026 at 2:02 PM
The differential diagnosis for interstitial hemorrhage includes hemorrhagic necrosis in the setting of renal artery thrombosis, infection (e.g. herpes simplex virus, adenovirus, hantavirus, Rickettsia),...(1/2)
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
1/ A very common vascular histologic finding in patients with hypertensive nephrosclerosis is arteriosclerosis. In advanced lesions, such as this example, there is prominent intimal fibrosis with narrowing of the vessel lumen.
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
January 28, 2025 at 2:15 PM
1/ A very common vascular histologic finding in patients with hypertensive nephrosclerosis is arteriosclerosis. In advanced lesions, such as this example, there is prominent intimal fibrosis with narrowing of the vessel lumen.
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
(1/2) The picture shows tissue submitted for routine immunofluorescence (fibrinogen stain is shown). Careful inspection confirms that this is an artery cross section which contains abnormal intraluminal tissue elements with numerous cleft-like spaces (see arrow).
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
November 25, 2025 at 5:21 PM
(1/2) The picture shows tissue submitted for routine immunofluorescence (fibrinogen stain is shown). Careful inspection confirms that this is an artery cross section which contains abnormal intraluminal tissue elements with numerous cleft-like spaces (see arrow).
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
1/ This biopsy is taken from a patient with HIV/AIDS who presented with an elevated serum creatinine and nephrotic range proteinuria.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
April 28, 2026 at 1:01 PM
1/ This biopsy is taken from a patient with HIV/AIDS who presented with an elevated serum creatinine and nephrotic range proteinuria.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
This renal biopsy illustrates severe chronic kidney injury and its effects on all major compartments of the cortex: most glomeruli are globally sclerotic, the atrophic tubules are widely spaced, the interstitium is fibrotic, and the arterial walls show intimal fibrosis.
#TeachingPoints #pathology
#TeachingPoints #pathology
April 14, 2026 at 1:02 PM
This renal biopsy illustrates severe chronic kidney injury and its effects on all major compartments of the cortex: most glomeruli are globally sclerotic, the atrophic tubules are widely spaced, the interstitium is fibrotic, and the arterial walls show intimal fibrosis.
#TeachingPoints #pathology
#TeachingPoints #pathology
1/ These photomicrographs show the classic immunofluorescence staining pattern for anti-LRP2 nephropathy, a disease that leads to severe renal tubular injury and is associated with circulating autoantibodies to the tubular brush border protein LRP2/megalin.
#ABBA #ABBAday #TeachingPoints #Pathology
#ABBA #ABBAday #TeachingPoints #Pathology
April 9, 2025 at 4:05 PM
1/ These photomicrographs show the classic immunofluorescence staining pattern for anti-LRP2 nephropathy, a disease that leads to severe renal tubular injury and is associated with circulating autoantibodies to the tubular brush border protein LRP2/megalin.
#ABBA #ABBAday #TeachingPoints #Pathology
#ABBA #ABBAday #TeachingPoints #Pathology
This biopsy shows glomerular arteriolar and capillary thrombi characteristic of thrombotic microangiopathy (TMA). Immunofluorescence studies (not shown) are negative for significant glomerular or tubulointerstitial immune complex deposits.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
March 31, 2026 at 1:03 PM
This biopsy shows glomerular arteriolar and capillary thrombi characteristic of thrombotic microangiopathy (TMA). Immunofluorescence studies (not shown) are negative for significant glomerular or tubulointerstitial immune complex deposits.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
Figure 1 shows a renal biopsy from a 29-year-old man with no significant past medical history, who was found to have microscopic hematuria and non-nephrotic range proteinuria.
#igan #iganawareness #iganday #iganephropathy #TeachingPoints #kidneypath #renal #pathology
#igan #iganawareness #iganday #iganephropathy #TeachingPoints #kidneypath #renal #pathology
May 14, 2026 at 1:03 PM
Figure 1 shows a renal biopsy from a 29-year-old man with no significant past medical history, who was found to have microscopic hematuria and non-nephrotic range proteinuria.
#igan #iganawareness #iganday #iganephropathy #TeachingPoints #kidneypath #renal #pathology
#igan #iganawareness #iganday #iganephropathy #TeachingPoints #kidneypath #renal #pathology
1/ Knowing whether a patient has clinical nephrotic syndrome and knowing the degree of podocyte foot process effacement can be helpful diagnostic clues in separating “primary” from “secondary” forms of focal segmental glomerulosclerosis (FSGS).
#TeachingPoints #kidneypath #pathology #pathsky
#TeachingPoints #kidneypath #pathology #pathsky
September 30, 2025 at 1:03 PM
1/ Knowing whether a patient has clinical nephrotic syndrome and knowing the degree of podocyte foot process effacement can be helpful diagnostic clues in separating “primary” from “secondary” forms of focal segmental glomerulosclerosis (FSGS).
#TeachingPoints #kidneypath #pathology #pathsky
#TeachingPoints #kidneypath #pathology #pathsky
1/ Bile cast nephropathy is one cause of acute or chronic kidney injury in patients with liver disease (especially obstructive cholestasis). Figure 1 shows two paraffin blocks containing kidney biopsies from two different patients.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
August 12, 2025 at 1:03 PM
1/ Bile cast nephropathy is one cause of acute or chronic kidney injury in patients with liver disease (especially obstructive cholestasis). Figure 1 shows two paraffin blocks containing kidney biopsies from two different patients.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
1/ This biopsy was performed on a 58 year old female who presented with mild proteinuria. The glomeruli show diffuse and global endocapillary hypercellularity with segmental double contour formation of the capillary loops on silver stain (Fig 1).
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
December 18, 2024 at 2:15 PM
1/ This biopsy was performed on a 58 year old female who presented with mild proteinuria. The glomeruli show diffuse and global endocapillary hypercellularity with segmental double contour formation of the capillary loops on silver stain (Fig 1).
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
Some patients with membranous glomerulopathy also have associated focal segmental glomerulosclerosis (FSGS) lesions.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
March 24, 2026 at 1:01 PM
Some patients with membranous glomerulopathy also have associated focal segmental glomerulosclerosis (FSGS) lesions.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
Prominent interstitial eosinophils (see arrow) are most often associated with allergic-type acute interstitial nephritis (AIN).
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
January 20, 2026 at 2:01 PM
Prominent interstitial eosinophils (see arrow) are most often associated with allergic-type acute interstitial nephritis (AIN).
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
1/ While the trichrome stain is best known for assessing the extent of interstitial fibrosis, it is a versatile stain with many applications.
#TeachingPoints #kidneypath #renal #pathology #pathsky
#TeachingPoints #kidneypath #renal #pathology #pathsky
June 17, 2025 at 1:04 PM
1/ While the trichrome stain is best known for assessing the extent of interstitial fibrosis, it is a versatile stain with many applications.
#TeachingPoints #kidneypath #renal #pathology #pathsky
#TeachingPoints #kidneypath #renal #pathology #pathsky
1/ The image in Figure 1 shows mild intimal arteritis in an allograft biopsy from a patient who had undergone a kidney transplant.
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
April 15, 2025 at 1:05 PM
1/ The image in Figure 1 shows mild intimal arteritis in an allograft biopsy from a patient who had undergone a kidney transplant.
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
1/ Polyomavirus nephropathy (PVN), predominantly caused by BK virus reactivation in the urogenital tract, is an important complication of renal allografts (reference 1).
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
December 24, 2024 at 2:15 PM
1/ Polyomavirus nephropathy (PVN), predominantly caused by BK virus reactivation in the urogenital tract, is an important complication of renal allografts (reference 1).
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
1/ Polarizable calcium oxalate microcrystals in a 16-year-old who ingested a small volume (<10 mL) of oxalic acid solution + grain alcohol (90% ethanol).
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
April 29, 2025 at 1:05 PM
1/ Polarizable calcium oxalate microcrystals in a 16-year-old who ingested a small volume (<10 mL) of oxalic acid solution + grain alcohol (90% ethanol).
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal