Image Credit (for oil painting, Malpighi): Wellcome Collection (https://wellcomecollection.org/)
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
Wellcome Collection
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June 2, 2026 at 1:01 PM
Image Credit (for oil painting, Malpighi): Wellcome Collection (https://wellcomecollection.org/)
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
One of the many patterns of tubular atrophy in the kidney is the aptly named “thyroidization” pattern because of its resemblance to normal thyroid gland follicles.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
May 27, 2026 at 1:02 PM
One of the many patterns of tubular atrophy in the kidney is the aptly named “thyroidization” pattern because of its resemblance to normal thyroid gland follicles.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
Figure 1 shows a renal biopsy from a 29-year-old man with no significant past medical history, who was found to have microscopic hematuria and non-nephrotic range proteinuria.
#igan #iganawareness #iganday #iganephropathy #TeachingPoints #kidneypath #renal #pathology
#igan #iganawareness #iganday #iganephropathy #TeachingPoints #kidneypath #renal #pathology
May 14, 2026 at 1:03 PM
Figure 1 shows a renal biopsy from a 29-year-old man with no significant past medical history, who was found to have microscopic hematuria and non-nephrotic range proteinuria.
#igan #iganawareness #iganday #iganephropathy #TeachingPoints #kidneypath #renal #pathology
#igan #iganawareness #iganday #iganephropathy #TeachingPoints #kidneypath #renal #pathology
1/ This biopsy is taken from a patient with HIV/AIDS who presented with an elevated serum creatinine and nephrotic range proteinuria.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
April 28, 2026 at 1:01 PM
1/ This biopsy is taken from a patient with HIV/AIDS who presented with an elevated serum creatinine and nephrotic range proteinuria.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
This renal biopsy illustrates severe chronic kidney injury and its effects on all major compartments of the cortex: most glomeruli are globally sclerotic, the atrophic tubules are widely spaced, the interstitium is fibrotic, and the arterial walls show intimal fibrosis.
#TeachingPoints #pathology
#TeachingPoints #pathology
April 14, 2026 at 1:02 PM
This renal biopsy illustrates severe chronic kidney injury and its effects on all major compartments of the cortex: most glomeruli are globally sclerotic, the atrophic tubules are widely spaced, the interstitium is fibrotic, and the arterial walls show intimal fibrosis.
#TeachingPoints #pathology
#TeachingPoints #pathology
Immunotactoid glomerulopathy is one of many glomerular diseases characterized by organized deposits.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
April 7, 2026 at 1:17 PM
Immunotactoid glomerulopathy is one of many glomerular diseases characterized by organized deposits.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
This biopsy shows glomerular arteriolar and capillary thrombi characteristic of thrombotic microangiopathy (TMA). Immunofluorescence studies (not shown) are negative for significant glomerular or tubulointerstitial immune complex deposits.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
March 31, 2026 at 1:03 PM
This biopsy shows glomerular arteriolar and capillary thrombi characteristic of thrombotic microangiopathy (TMA). Immunofluorescence studies (not shown) are negative for significant glomerular or tubulointerstitial immune complex deposits.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
Some patients with membranous glomerulopathy also have associated focal segmental glomerulosclerosis (FSGS) lesions.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
March 24, 2026 at 1:01 PM
Some patients with membranous glomerulopathy also have associated focal segmental glomerulosclerosis (FSGS) lesions.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
As published decades ago by Bonsib et al. (see reference), fluorescence microscopy of eosin-stained frozen section slides can be a valuable tool in providing diagnostic clues in kidney biopsies.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
March 17, 2026 at 1:02 PM
As published decades ago by Bonsib et al. (see reference), fluorescence microscopy of eosin-stained frozen section slides can be a valuable tool in providing diagnostic clues in kidney biopsies.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
1/ This allograft biopsy shows the characteristic features of adenovirus infection.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
March 10, 2026 at 1:01 PM
1/ This allograft biopsy shows the characteristic features of adenovirus infection.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
2/ Predominantly subepithelial deposits, in contrast, would be expected in most cases of membranous glomerulopathy.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
March 3, 2026 at 2:02 PM
2/ Predominantly subepithelial deposits, in contrast, would be expected in most cases of membranous glomerulopathy.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
The differential diagnosis for interstitial hemorrhage includes hemorrhagic necrosis in the setting of renal artery thrombosis, infection (e.g. herpes simplex virus, adenovirus, hantavirus, Rickettsia),...(1/2)
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
February 10, 2026 at 2:02 PM
The differential diagnosis for interstitial hemorrhage includes hemorrhagic necrosis in the setting of renal artery thrombosis, infection (e.g. herpes simplex virus, adenovirus, hantavirus, Rickettsia),...(1/2)
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
(1/3) Chronic active T cell-mediated rejection (TCMR) was included in the 2017 Banff classification system for the evaluation of kidney allografts (see reference).
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
February 3, 2026 at 2:02 PM
(1/3) Chronic active T cell-mediated rejection (TCMR) was included in the 2017 Banff classification system for the evaluation of kidney allografts (see reference).
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
Collapsing glomerular lesions are aptly named, given the prominent “collapse” of glomerular tuft capillary loops. There is also hyperplasia and hypertrophy of overlying epithelial cells, and protein resorption droplets may be abundant (see arrow).
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
January 27, 2026 at 2:02 PM
Collapsing glomerular lesions are aptly named, given the prominent “collapse” of glomerular tuft capillary loops. There is also hyperplasia and hypertrophy of overlying epithelial cells, and protein resorption droplets may be abundant (see arrow).
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
Prominent interstitial eosinophils (see arrow) are most often associated with allergic-type acute interstitial nephritis (AIN).
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
January 20, 2026 at 2:01 PM
Prominent interstitial eosinophils (see arrow) are most often associated with allergic-type acute interstitial nephritis (AIN).
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
1/ This kidney biopsy is from an elderly adult patient with acute renal failure and a history of non-steroidal anti-inflammatory medication (NSAID) use.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
December 30, 2025 at 2:02 PM
1/ This kidney biopsy is from an elderly adult patient with acute renal failure and a history of non-steroidal anti-inflammatory medication (NSAID) use.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
(1/2) The picture shows tissue submitted for routine immunofluorescence (fibrinogen stain is shown). Careful inspection confirms that this is an artery cross section which contains abnormal intraluminal tissue elements with numerous cleft-like spaces (see arrow).
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
November 25, 2025 at 5:21 PM
(1/2) The picture shows tissue submitted for routine immunofluorescence (fibrinogen stain is shown). Careful inspection confirms that this is an artery cross section which contains abnormal intraluminal tissue elements with numerous cleft-like spaces (see arrow).
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
(1/2) The presence of peritubular capillaritis (see arrow Fig. 1) is an important component of microvascular inflammation, along with glomerulitis, in the diagnosis of active antibody-mediated rejection (ABMR).
#TeachingPoints #kidneypath #renal #pathology #nephsky #pathsky
#TeachingPoints #kidneypath #renal #pathology #nephsky #pathsky
November 18, 2025 at 2:03 PM
(1/2) The presence of peritubular capillaritis (see arrow Fig. 1) is an important component of microvascular inflammation, along with glomerulitis, in the diagnosis of active antibody-mediated rejection (ABMR).
#TeachingPoints #kidneypath #renal #pathology #nephsky #pathsky
#TeachingPoints #kidneypath #renal #pathology #nephsky #pathsky
1/ This biopsy shows the characteristic features of uric acid nephropathy (commonly known as gout), which results from precipitation of uric acid in the kidney parenchyma.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
November 11, 2025 at 2:02 PM
1/ This biopsy shows the characteristic features of uric acid nephropathy (commonly known as gout), which results from precipitation of uric acid in the kidney parenchyma.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
(1/3) Paying close attention to morphologic detail can sometimes suggest etiologic clues in cases of severe chronic renal injury. The glomerulus in this image, for example, shows near complete global glomerulosclerosis.
#TeachingPoints #kidneypath #nephsky #pathsky #renal
#TeachingPoints #kidneypath #nephsky #pathsky #renal
October 28, 2025 at 1:02 PM
(1/3) Paying close attention to morphologic detail can sometimes suggest etiologic clues in cases of severe chronic renal injury. The glomerulus in this image, for example, shows near complete global glomerulosclerosis.
#TeachingPoints #kidneypath #nephsky #pathsky #renal
#TeachingPoints #kidneypath #nephsky #pathsky #renal
Cholesterol emboli involving the kidney may manifest clinically as acute kidney injury, hematuria, proteinuria (both non-nephrotic and nephrotic range), and even new onset hypertension.
#TeachingPoints #kidneypath #renal #pathology #nephx #pathx
#TeachingPoints #kidneypath #renal #pathology #nephx #pathx
October 14, 2025 at 1:02 PM
Cholesterol emboli involving the kidney may manifest clinically as acute kidney injury, hematuria, proteinuria (both non-nephrotic and nephrotic range), and even new onset hypertension.
#TeachingPoints #kidneypath #renal #pathology #nephx #pathx
#TeachingPoints #kidneypath #renal #pathology #nephx #pathx
However, the prominent IgG deposits also involving the associated arteriole in this case are an important clue that helps argue for a secondary etiology. This patient, in fact, was found to have systemic lupus erythematosus. (2/2)
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
October 7, 2025 at 12:55 PM
However, the prominent IgG deposits also involving the associated arteriole in this case are an important clue that helps argue for a secondary etiology. This patient, in fact, was found to have systemic lupus erythematosus. (2/2)
#TeachingPoints #kidneypath #renal
#TeachingPoints #kidneypath #renal
1/ Knowing whether a patient has clinical nephrotic syndrome and knowing the degree of podocyte foot process effacement can be helpful diagnostic clues in separating “primary” from “secondary” forms of focal segmental glomerulosclerosis (FSGS).
#TeachingPoints #kidneypath #pathology #pathsky
#TeachingPoints #kidneypath #pathology #pathsky
September 30, 2025 at 1:03 PM
1/ Knowing whether a patient has clinical nephrotic syndrome and knowing the degree of podocyte foot process effacement can be helpful diagnostic clues in separating “primary” from “secondary” forms of focal segmental glomerulosclerosis (FSGS).
#TeachingPoints #kidneypath #pathology #pathsky
#TeachingPoints #kidneypath #pathology #pathsky
1/ Electron microscopy can be helpful in the diagnosis of cryoglobulinemic glomerulonephritis.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
September 9, 2025 at 1:03 PM
1/ Electron microscopy can be helpful in the diagnosis of cryoglobulinemic glomerulonephritis.
#TeachingPoints #kidneypath #renal #pathology
#TeachingPoints #kidneypath #renal #pathology
1/This glomerulus is large! Glomerular enlargement, or glomerulomegaly, may be diagnosed when a glomerulus sectioned through the hilum fills greater than 50% of a 40x microscopic field. It is thought to be a morphologic marker of glomerular hyperfiltration.
#TeachingPoints #kidneypath #pathology
#TeachingPoints #kidneypath #pathology
August 26, 2025 at 1:02 PM
1/This glomerulus is large! Glomerular enlargement, or glomerulomegaly, may be diagnosed when a glomerulus sectioned through the hilum fills greater than 50% of a 40x microscopic field. It is thought to be a morphologic marker of glomerular hyperfiltration.
#TeachingPoints #kidneypath #pathology
#TeachingPoints #kidneypath #pathology