#TreatmentResistant
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drolma-and-momo.bsky.social
#ChronicPain #DailyStruggle #InvisibleIllness #Disability #ListenToPatients

The level of pain I feel 24/7 now is so far beyond what used to send me to the E.R. Some of us are #MedicationResistant #TreatmentResistant
December 26, 2024 at 8:26 PM
psypost.bsky.social
A small, preliminary study suggests that a single intramuscular ketamine injection may rapidly ease symptoms in patients with treatment-resistant obsessive-compulsive disorder. #Ketamine #OCD #MentalHealth #Psychiatry #TreatmentResistant
Ketamine shows promise for severe obsessive-compulsive disorder in new study
A small, preliminary study suggests that a single intramuscular ketamine injection may rapidly ease symptoms in patients with treatment-resistant obsessive-compulsive disorder.
www.psypost.org
February 12, 2025 at 3:19 PM
polymniag.bsky.social
Thrilled to share our latest research studying the role of HPA axis hormones in major depression and antidepressant effects of ketamine.
www.sciencedirect.com/science/arti...

#DepressionResearch #Ketamine #HPAaxis #MentalHealthScience #antidepressant #treatmentresistant
Associations between hypothalamic-pituitary-adrenal (HPA) axis hormone levels, major depression features and antidepressant effects of ketamine
Subanesthetic doses of (R,S)-ketamine (ketamine) have demonstrated rapid and robust antidepressant effects in individuals with depression. However, in…
www.sciencedirect.com
December 13, 2024 at 5:48 PM
noqualiaonlyus.bsky.social
Calling all chronic illness or treatment-resistant/TRD girlies!!! here may be some answers to consider: RCCX gene cluster web.archive.org/web/20231214...

#chronicillness #disability #treatmentresistant #RCCX #genetics #psychology #medicine
Hypermobility, RCCX Theory and One Journey From Illness Towards Wholeness
by Courtney Snyder, MD The human body is a mystery.  As much and as fast as we’re learning, we still know very little.  This post is about a recent discovery.  I call it a “discovery,”...
web.archive.org
November 17, 2024 at 7:03 PM
drleeds.bsky.social
Interventional psychiatry (ketamine-assisted therapy) focuses on treatment-resistant depression, anxiety, trauma, and PTSD when standard medications fail. #InterventionalPsychiatry #TreatmentResistant #MentalHealthCare
August 18, 2025 at 8:32 PM
jerryfess.bsky.social
open.substack.com/pub/fessupbl...

#depression #mentalhealth #spravato #vns #treatmentresistant

Follow my blog “Fess Up! My Journal Out Loud” on substack. It’s FREE!!
No One Is Coming to Save You… Or Are They?
No one can fix it for you, but that doesn’t mean you’re on your own
open.substack.com
April 10, 2026 at 2:01 PM
rostunbrokentn.bsky.social
📢 Post 1: Since 2016, I've lived with treatment-resistant trigeminal neuralgia
Continue below in the photo ⬇️

#TrigeminalNeuralgia #TreatmentResistant #ChronicPain #PainAwareness #Since201
#BeyondTheHorizon #HorizonForbiddenWest
📢 Post 1: Since 2016, I’ve lived with treatment-resistant trigeminal neuralgia Hey everyone, Since 2016, I’ve been living with one of the most painful conditions in the world: treatment-resistant trigeminal neuralgia. What does that mean? Imagine the most important nerve in your face—the trigeminal nerve—as an exposed, high-voltage power line: Trigeminal neuralgia causes sudden, electric shocks of pain, as if lightning were striking through your face. These attacks often come without warning and can last for seconds, minutes, or even hours—especially when the condition is treatment-resistant. “Treatment-resistant” means: No standard treatment—no medication, surgery, or therapy—can stop the pain long-term. There is no pill, no injection, no therapy that can simply “turn off” the pain. Since 2016, I’ve been searching for a solution—and in the meantime, I live with constant, unpredictable pain attacks that severely limit my life. Why I’m sharing this This condition is invisible, but the pain is real. If you ever notice me reacting differently in certain situations, now you’ll understand why. 💙 Thanks for listening. Questions? Feel free to DM me. #TrigeminalNeuralgia #TreatmentResistant #ChronicPain #PainAwareness #Since2016
August 2, 2026 at 12:44 PM
rostunbrokentn.bsky.social
📢 Post 2: How you can help when I face hate messages online
Continue below the photo ⬇️

#TrigeminalNeuralgia #TreatmentResistant #ChronicPain #HateSpeech #SupportMatters #Since2016 #BeyondTheHorizon #HorizonForbiddenWest
Hey everyone, In my first post, I explained what treatment-resistant trigeminal neuralgia means and that I’ve lived with it since 2016. Today, I want to share how you can support me when I’m confronted with hate, mockery, or stress online—because for me, it’s not just an emotional challenge. It triggers real, physical pain. Why hate messages are dangerous for me When I’m exposed to stress, mockery, or hate online, my body releases stress hormones like adrenaline and cortisol. These act like an electric shock surging through my exposed nerve—triggering brutal pain attacks. 👉 For me, “ignoring hate” isn’t a mental exercise. My nervous system reacts automatically and uncontrollably, before I can even process it consciously. It’s like someone flipping a switch—and the pain is real, intense, and overwhelming. How you can help me If you see me facing hate online: ✅ Send calming messages—not advice, but supportive words like: “I’m so sorry you had to experience that. I’m here for you.” “You’re not alone—I’ve got your back.” “You don’t need to justify yourself. I support you.” ✅ Stand up against hate posters by: Reporting or blocking toxic comments. Making it clear such messages are unacceptable, e.g.: “This isn’t okay. Respect is the baseline.” ❌ Don’t ask, “Why do you put up with this?” or “Can’t you just ignore it?”—because for me, that doesn’t trigger a mental decision. It triggers physical pain. Why I sometimes step back Sometimes, it’s medically necessary for me to withdraw—not out of fear, but to protect my body from extreme pain. Social media can become a trap of overstimulation that threatens my health. 💙 Thank you for understanding. If you see me facing hate, be my voice of calm and protection. Have questions or want to know more? Feel free to DM me. I appreciate every kind word—no pressure, just support.
August 2, 2026 at 12:58 PM
flipso.com
A pacemaker for the brain helped a woman with crippling depression. It may soon offer hope to others

🟦 Bias L
https://apnews.com/article/treatmentresistant-depression-dbs-deep-brain-stimulation-26383d6e5f9eb797485b7bc277cac59c
February 21, 2024 at 5:21 AM
sigtrans-sttt.bsky.social
Targeting LRRC15⁺ cells with [¹⁷⁷Lu]Lu-DUNP19 enables precise imaging and #radiotherapy, reprograms the #immunosuppressive #TumorMicroEnvironment & offers a strategy against #TreatmentResistant #cancers. @uofcalifornia.bsky.social

#FeaturedArticle #STTT: doi.org/10.1038/s413...
October 31, 2025 at 12:01 AM
rcatanho.bsky.social
Lorundostrat, inhibidor de la aldosterona sintasa, es eficaz y seguro para reducir la presión arterial en adultos con hipertensión no controlada, incluyendo los resistentes al tratamiento #treatmentresistant #hypertension #lorundostrat jamanetwork.com/journals/jam...
Lorundrostat for Adults With Uncontrolled and Treatment-Resistant Hypertension
This randomized clinical trial compares the efficacy and safety of lorundrostat for lowering blood pressure when added to a prescribed antihypertensive regimen of 2 to 5 medications vs placebo among p...
jamanetwork.com
July 3, 2025 at 8:39 AM
kidneystories.bsky.social
Association between 'Life's Essential 8' cardiovascular health and apparent ... - Frontiers - goo.gl/alerts/ibxhCc #GoogleAlerts
Frontiers | Association between 'Life's Essential 8' cardiovascular health and apparent treatmentresistant hypertension among US adults from the NHANES,2005 to 2018
The association between healthy lifestyle and American Heart Association (AHA) Life's Essential 8 (LE8) score and apparent treatment-resistant hypertension(a...
goo.gl
December 3, 2024 at 12:22 AM