#TregCells
#Bcl6 inhibition destabilizes #TregCells by reducing H3K4me3, enhancing #AntiTumor immunity, delaying #HeadandNeckSquamousCellCarcinoma progression, and synergizing with immune checkpoint therapy, highlighting Bcl6 as a promising target.

#OpenAccess: doi.org/10.1016/j.ge...
March 31, 2026 at 4:45 PM
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Published on Thursday, October 23, 2025
Successful experiments reprogram rogue T cells for targeted autoimmune disease therapy
Two teams of researchers have developed a cell reprogramming technology that converts rogue disease-causing T cells from our immune system into protective Tregcells. These cells help ensure that the i...
medicalxpress.com
October 24, 2025 at 1:04 PM
A new cell reprogramming approach converts disease-causing T cells into protective regulatory cells, offering targeted therapy for autoimmune conditions without broad immune suppression. doi.org/g97smr
Successful experiments reprogram rogue T cells for targeted autoimmune disease therapy
Two teams of researchers have developed a cell reprogramming technology that converts rogue disease-causing T cells from our immune system into protective Tregcells.
medicalxpress.com
October 23, 2025 at 4:30 PM
Intestinal #TregCells promote epithelial repair by combining #IFNγ and #IL10 signaling to drive #organoid growth, preserve #IntestinalStemCells, and enable #gut regeneration.
@tum.de @univparissaclay.bsky.social

#OpenAccess in #STTT: doi.org/10.1038/s413...
February 4, 2026 at 12:30 PM
Specific abrogation of Bcl6 in #TregCells delays the malignant transformation in the 4NQO-induced HNSCC model by impairing the lineage stability of Treg cells via down-regulating #histone H3K4 #trimethylation. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...
May 9, 2025 at 2:31 PM