Newswise — Conventional disinfection methods such as chlorination and ozonation have notable limitations: they generate harmful disinfection by-products, cause non-selective damage to aquatic microbial communities, and often fail to eliminate ARGs carried by bacteria or bacterial debris. Meanwhile, V. parahaemolyticus—a Gram-negative bacterium widely distributed in marine and estuarine environments—has increasingly acquired MDR to critically important antibiotics including β-lactams, tetracyclines, and fluoroquinolones. The situation is further exacerbated by biofilms that enhance the pathogen’s tolerance to antibiotics and facilitate horizontal gene transfer of resistance genes. Due to these challenges, there is an urgent need for alternative strategies that can effectively reduce resistant bacterial populations and mitigate the spread of resistance determinants. A team of researchers from the Shandong Key Laboratory of Coastal Zone Environmental Processes and Ecological Security at the Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, together with collaborators from the University of Chinese Academy of Sciences, Harbin Engineering University, and the University of Florida, report (DOI: 10.1007/s11783-026-2279-5) these findings in the journal ENGINEERING Environment (Volume 20, Issue 12, Article 179, 2026;). The team isolated a novel lytic bacteriophage—named VBY—from coastal aquaculture tailwater and systematically evaluated its disinfection performance against MDR V. parahaemolyticus. Phage VBY is a Caudoviricetes...

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