#ZNF600
Jiongming He, Shan Liu, Lingying Wang & Fei Xiong report that #EsophagealCancer cells impair #NKcell function via the downregulation of #ZNF600 expression through the ligation of #CEACAM1 with #TIM3
Zinc finger protein 600 is essential for the cytotoxic function of esophageal cancer-associated natural killer cells
ZNF600 enhances the cytolytic activity of NK cells. EC cells downregulate ZNF600 expression in EC-associated NK cells via the ligation of CEACAM1 to TIM-3
doi.org
September 18, 2026 at 4:06 PM