#alendronate
Hell yeah I got horse pills to treat my osteoporosis. Gotta take these shits with like 12 oz of water, this is gonna rule
October 3, 2026 at 7:23 PM
#ThrowbackThursday in JHC: "Alendronate Alters the Release of EVs by Raw 264.7 Osteoclasts."

Click to read for FREE: bit.ly/4oz6iVQ

#alendronate #bisphosphonate #osteoclast
October 8, 2026 at 3:48 PM
Fosforus? You mean like in alendronate?

Sorry....
May 18, 2026 at 11:52 AM
🦴🔬 A 'forever unpublished' image! This histological section of the human jaw bone shows large amounts of new bone (intensely stained areas) after switching from a bisphosphonate (alendronate) to denosumab as the anti-osteoporotic drug.

Thoughts?

#bone #histology #histopathology #microscopy 🧪
March 19, 2025 at 9:15 PM
Romosozumab followed by alendronate significantly enhances bone microarchitecture in postmenopausal women with osteoporosis compared to alendronate alone.

by McClung MR, Betah D (...) Wang Z et 4 al. in J Bone Miner Res #MedSky

📖 read the article:
Romosozumab improves microarchitecture as assessed by tissue thickness–adjusted trabecular bone score in postmenopausal women with osteoporosis
Abstract. Bone mineral density (BMD) is only one of several bone strength determinants affected by osteoporosis therapies. Trabecular Bone Score (TBS), a g
academic.oup.com
February 11, 2025 at 8:29 PM
it's not gender-affirming care until the HRT comes with a side of alendronate
August 5, 2026 at 12:53 AM
Romosozumab significantly enhances bone health indicators in postmenopausal women with osteoporosis and type 2 diabetes compared to alendronate alone.

by Ferrari S, Betah D (...) Dhaliwal R et 5 al. in J Clin Endocrinol Metab #MedSky

📖 read the article:
Romosozumab Improves Tissue Thickness–Adjusted Trabecular Bone Score in Women With Osteoporosis and Diabetes
AbstractContext. Trabecular bone score (TBS), a gray-level texture index derived from lumbar spine (LS) dual-energy x-ray absorptiometry (DXA) scans, is de
academic.oup.com
February 2, 2025 at 6:34 AM
Alendronate therapy does not enhance survival rates in osteoporosis patients, despite its effectiveness in reducing fracture risk. Rui Sun et al. Sci Prog 3 Sept 2024 shorturl.at/pyz2E …meta-analysis 13 RCT involving 15,560 participants
Does alendronate enhance survival rates in osteoporosis patients? A meta-analysis of randomized controlled trials - Rui Sun, Zhibin Lan, Gang Wu, Qi Ma, Di Xue, Xue Lin, Qunhua Jin, 2025
Objectives This systematic review and meta-analysis aims to evaluate whether alendronate therapy improves survival rates in patients with osteoporosis, in addit...
shorturl.at
September 6, 2025 at 8:00 AM
"Bisphosphonates in Osteoporosis - Alendronate, Ibandronate, Risedronate & Etidronate" ( www.vhtc.org/2025/12/bisp... )
Bisphosphonates in Osteoporosis - Alendronate, Ibandronate, Risedronate & Etidronate
Bisphosphonates in Osteoporosis - Learn bisphosphonates used in osteoporosis—Alendronate, Ibandronate, Risedronate, and Etidronate.
www.vhtc.org
December 21, 2025 at 10:39 AM
Happening tomorrow (October 7th) at 10AM EST (3PM UK time) 🚨 ZDMS Skeletal Diseases RIG Webinar! It’s FREE to attend and open to everyone 😊 And there’s still time to register using this link: us06web.zoom.us/meeting/regi... 🐟🦴 We hope to see you online!

#ZDMS #DiseaseModels #zebrafish #killifish
October 6, 2026 at 7:18 PM
Fosamax is the brand name of alendronate, a first-choice oral tablet prescribed for #osteoporosis. Lifestyle approaches always matter for bone health. But people with osteoporosis often benefit from medication to lower the risk of painful bone breaks.
@daphneberryhill.bsky.social
Should I take Fosamax for osteoporosis if I feel fine?
Fosamax is the brand name of alendronate, a first-choice oral tablet prescribed for osteoporosis.
thosenerdygirls.substack.com
February 5, 2026 at 10:10 AM
This is interesting! I already knew about the interactions between coffee and alendronate, and also with thyreoid medications.
BUT it also means that I didn't hallucinate the bronchodilatory effect of coffee 😃
October 1, 2025 at 3:56 AM
While likely not the case in your patients who respond to palmidronate… I have seen hypercalcemia in older patients on alendronate for long periods. ?low bone turnover. Resolved after off alendronate for several months.
February 21, 2025 at 4:28 AM
Oooooof. Idk about interactions with thyroid meds but the alendronate has made a huge difference for this goober. She could theoretically have the SUB taken out at this point. Hope you find the right mix of meds for your boy!
August 1, 2026 at 5:01 PM
Cerium-Doped, Alendronate-Loaded, Metal–Organic Framework Nanodrug for Delayed Osteoporosis Progress http://dx.doi.org/10.1021/acsanm.4c05640
December 9, 2024 at 2:12 PM
Ha yes I wish it were better! Some of the key osteoporosis trials (e.g. alendronate) are >97% White.
May 27, 2025 at 1:22 AM
We struggle so much was long-term treatment protocols in the current clinical trial paradigm. How should we use these things long-term? No one knows. We have some alendronate trials up to 5 years. IMO: this is one of the primary causes of undertreatment.
January 19, 2025 at 3:07 PM
🦴How do denosumab and bisphosphonates compare at improving bone density?

In the initial years there is similar improvement. 📈

Continued denosumab leads to benefit, but benefit of zoledronate or alendronate is minimal after 3 years.

This difference is one of many when considering anti-resorptives
November 18, 2024 at 7:08 AM
Take a look at the recent work by Craig M. Forsyth, Glen B. Deacon and @peterjunk.bsky.social on directing alendronate structures into 2-D layers with bulky quaternary phosphonium cations. 👀👇

🔗 doi.org/10.1039/D5CE...
📍 Monash University; James Cook University 🧪
April 17, 2026 at 7:00 AM
Comparing the stability of implants coated with nano PLGA-alendronate sodium: an in-vivo study
Vahid Naemi, Abbas Haghighat, Mahla Esfahanian
doi.org/10.2340/biid...
April 7, 2025 at 2:28 PM
#HIV- Forschung: Das Forschungsnetzwerk ACTG (#AIDS Clinical Trials Group) hat die Studie #STAIR-HIV (A5163) gestartet. Untersucht werden soll, ob die gegen Osteoporose wirksame Substanz Alendronat die Reservoire an latenten (ruhenden) #HIV- infizierten Zellen reduzieren kann.
ACTG launches alendronate trial to test HIV reservoir clearance
The global HIV trials network is testing a common osteoporosis drug as a latency-reversing agent in a 30-person randomised, placebo-controlled study.
biotech.disruptsmedia.com
August 24, 2026 at 4:16 PM
I’ve been taking Alendronate for osteoporosis since I broke my hip October 2024. Just had a bone scan a couple months ago and no improvement. Still got osteoporosis so apparently the medication ain’t helping much. 🧐😳🙄
June 5, 2026 at 2:51 AM
In which condition is alendronate (Fosamax) CONTRAindicated?

A. Hepatic impairment

B. Hypercalcemia

C. Inability to sit/stand upright for 30 minutes

D. Paget’s disease of bone

The answer is in the thread
#PhunQuiz
February 28, 2025 at 2:33 AM