Phase 3 trials evaluate #suzetrigine, a selective NaV1.8 inhibitor, for moderate-to-severe #acutepain.
📊 LSMD SPID48 vs. placebo:
• Abdominoplasty: 48.4 (P < .0001)
• Bunionectomy: 29.3 (P = .0002)
Read the review: https://bit.ly/4gtTE9H
#PainManagement #ClinicalTrials
📊 LSMD SPID48 vs. placebo:
• Abdominoplasty: 48.4 (P < .0001)
• Bunionectomy: 29.3 (P = .0002)
Read the review: https://bit.ly/4gtTE9H
#PainManagement #ClinicalTrials
September 15, 2026 at 5:56 PM
Phase 3 trials evaluate #suzetrigine, a selective NaV1.8 inhibitor, for moderate-to-severe #acutepain.
📊 LSMD SPID48 vs. placebo:
• Abdominoplasty: 48.4 (P < .0001)
• Bunionectomy: 29.3 (P = .0002)
Read the review: https://bit.ly/4gtTE9H
#PainManagement #ClinicalTrials
📊 LSMD SPID48 vs. placebo:
• Abdominoplasty: 48.4 (P < .0001)
• Bunionectomy: 29.3 (P = .0002)
Read the review: https://bit.ly/4gtTE9H
#PainManagement #ClinicalTrials
Bunionectomy Market Trends & Growth Analysis 2035 - Wiseguy | WiseGuyReports www.wiseguyreports.com/reports/buni...
Bunionectomy Market Trends & Growth Analysis 2035 - Wiseguy
The Bunionectomy Market is expected to grow from 2,200 USD Million in 2025 to 4,000 USD Million by 2035. The Bunionectomy Market CAGR (growth rate) is expected to be around 6.3% | Wiseguy Reports
www.wiseguyreports.com
August 22, 2026 at 8:10 AM
Bunionectomy Market Trends & Growth Analysis 2035 - Wiseguy | WiseGuyReports www.wiseguyreports.com/reports/buni...
Yeah, this is what I ended up doing when I had my bunionectomy a few years ago once the pain was low enough that the being sick from the norcos they gave me was worse
August 12, 2026 at 2:20 PM
Yeah, this is what I ended up doing when I had my bunionectomy a few years ago once the pain was low enough that the being sick from the norcos they gave me was worse
He had a bunionectomy and saw the Light.
August 4, 2026 at 11:51 PM
He had a bunionectomy and saw the Light.
Oh it’s in a holding pattern. I had a bunionectomy that needs revised and when they do it they are going to shorten my second toe. It’s not top of list lol
August 1, 2026 at 10:06 PM
Oh it’s in a holding pattern. I had a bunionectomy that needs revised and when they do it they are going to shorten my second toe. It’s not top of list lol
This week in physical therapy I’ve seen a partial meniscectomy, biceps tenotomy, staged bunionectomy, and a neck fusion (cervical spinal fusion)
July 24, 2026 at 1:08 AM
This week in physical therapy I’ve seen a partial meniscectomy, biceps tenotomy, staged bunionectomy, and a neck fusion (cervical spinal fusion)
DYK? There are several procedures commonly used as surgical treatment for #bunions. The type of bunion correction procedure used will depend on: the extent of the deformity, the characteristics of the patient, and the preference of the surgeon.
Bunion Procedures (Bunionectomy)
The following procedures are commonly used as surgical treatment for bunions. The type of procedure used will depend on: the extent of the deformity, the characteristics of the patient, and the…
buff.ly
May 27, 2026 at 3:46 PM
DYK? There are several procedures commonly used as surgical treatment for #bunions. The type of bunion correction procedure used will depend on: the extent of the deformity, the characteristics of the patient, and the preference of the surgeon.
#VTRS U.S. FDA Accepts Viatris New Drug Application for Fast-Acting Meloxicam for the Treatment of Moderate-to-Severe Acute Pain
https://www.stocktitan.net/news/VTRS/u-s-fda-accepts-viatris-new-drug-application-for-fast-acting-1wj5qm6yrs92.html
https://www.stocktitan.net/news/VTRS/u-s-fda-accepts-viatris-new-drug-application-for-fast-acting-1wj5qm6yrs92.html
U.S. FDA Accepts Viatris New Drug Application for Fast-Acting Meloxicam for the Treatment of Moderate-to-Severe Acute Pain
Viatris (Nasdaq: VTRS) announced that the U.S. FDA has accepted its New Drug Application for MR-107A-02 fast-acting meloxicam, a non-opioid treatment for moderate-to-severe acute pain. The FDA set a PDUFA goal date of Dec. 27, 2026.The NDA is backed by two Phase 3 randomized, double-blind, placebo- and active-controlled trials in herniorrhaphy and bunionectomy patients. Fast-acting meloxicam met primary and secondary endpoints, reduced opioid use, and showed a safety profile consistent with its mechanism of action.
www.stocktitan.net
May 18, 2026 at 12:00 PM
#VTRS U.S. FDA Accepts Viatris New Drug Application for Fast-Acting Meloxicam for the Treatment of Moderate-to-Severe Acute Pain
https://www.stocktitan.net/news/VTRS/u-s-fda-accepts-viatris-new-drug-application-for-fast-acting-1wj5qm6yrs92.html
https://www.stocktitan.net/news/VTRS/u-s-fda-accepts-viatris-new-drug-application-for-fast-acting-1wj5qm6yrs92.html
So I’ve been laid up after foot surgery. I had a bunionectomy and a bone shortened. It’s a pretty dull recovery so far, but I did design and 3d print myself a cane. I design for the absurd
April 2, 2026 at 1:38 PM
So I’ve been laid up after foot surgery. I had a bunionectomy and a bone shortened. It’s a pretty dull recovery so far, but I did design and 3d print myself a cane. I design for the absurd
Life hack: If you need surgery, but can't afford the copay even w/ insurance - search for medical trials.
My bunionectomy was free, and I didn't need to use my PTO, because they paid me for each appointment & the 3 days I spent in a fancy hospital room for the post-op non-opioid pain med trials.
My bunionectomy was free, and I didn't need to use my PTO, because they paid me for each appointment & the 3 days I spent in a fancy hospital room for the post-op non-opioid pain med trials.
March 21, 2026 at 3:42 AM
Life hack: If you need surgery, but can't afford the copay even w/ insurance - search for medical trials.
My bunionectomy was free, and I didn't need to use my PTO, because they paid me for each appointment & the 3 days I spent in a fancy hospital room for the post-op non-opioid pain med trials.
My bunionectomy was free, and I didn't need to use my PTO, because they paid me for each appointment & the 3 days I spent in a fancy hospital room for the post-op non-opioid pain med trials.
Throw a bunionectomy scar and ingrown nail on one. No reason for those in particular 🫠
March 15, 2026 at 1:46 PM
Throw a bunionectomy scar and ingrown nail on one. No reason for those in particular 🫠
good news: I am taking medical leave from my master's degree and getting my second bunionectomy April 14 so I can spend time recovering
March 4, 2026 at 7:13 PM
good news: I am taking medical leave from my master's degree and getting my second bunionectomy April 14 so I can spend time recovering
If he takes off, is that a bunionectomy?
February 25, 2026 at 4:19 AM
If he takes off, is that a bunionectomy?
The McBride bunionectomy is a soft-tissue realignment surgery used to treat mild-to-moderate hallux valgus (bunions) by removing the bony bump, releasing the tightened adductor hallucis tendon, and repairing the joint capsule.
You straighten big toes Gerry
No pew pew for you
You straighten big toes Gerry
No pew pew for you
February 24, 2026 at 8:51 PM
The McBride bunionectomy is a soft-tissue realignment surgery used to treat mild-to-moderate hallux valgus (bunions) by removing the bony bump, releasing the tightened adductor hallucis tendon, and repairing the joint capsule.
You straighten big toes Gerry
No pew pew for you
You straighten big toes Gerry
No pew pew for you
I have to go see an orthopedist I have to choose for my ankle. I wanted to see my guy who did my bunionectomy years ago and who was omg so hot 🥵🥵🥵🥵 but he’s very popular now and I could only see his PA. I’m mad bc I was like, yes please penetrate me with your high-tech screws.
February 6, 2026 at 10:03 PM
I have to go see an orthopedist I have to choose for my ankle. I wanted to see my guy who did my bunionectomy years ago and who was omg so hot 🥵🥵🥵🥵 but he’s very popular now and I could only see his PA. I’m mad bc I was like, yes please penetrate me with your high-tech screws.
I'm three months out from a double keyhole bunionectomy, have pins in my toes, and am learning to walk again, but this is just next level! Recovery must be *so* hard. Damn!
September 21, 2025 at 7:09 PM
I'm three months out from a double keyhole bunionectomy, have pins in my toes, and am learning to walk again, but this is just next level! Recovery must be *so* hard. Damn!
Bunions are painful bony lumps that grow along the inside of your foot at the joint where your big toe meets your foot -- they grow slowly as the big toe angles inward. Learn how to treat bunions at home and determine if you need surgery to remove them (bunionectomy). wb.md/45awr6O
September 19, 2025 at 6:00 PM
Bunions are painful bony lumps that grow along the inside of your foot at the joint where your big toe meets your foot -- they grow slowly as the big toe angles inward. Learn how to treat bunions at home and determine if you need surgery to remove them (bunionectomy). wb.md/45awr6O
This woman having a lapidus bunionectomy then having her hammer toes fixed. On both feet. The surgery is 6.5 hours. How do surgeons go on for so long? I would be so hungry #MyFeetAreKillingMe
August 16, 2025 at 10:23 PM
This woman having a lapidus bunionectomy then having her hammer toes fixed. On both feet. The surgery is 6.5 hours. How do surgeons go on for so long? I would be so hungry #MyFeetAreKillingMe
Bunions on your feet? Learn how to treat bunions at home and determine if you need surgery to remove them (bunionectomy). wb.md/45eWjOZ
August 13, 2025 at 2:00 PM
Bunions on your feet? Learn how to treat bunions at home and determine if you need surgery to remove them (bunionectomy). wb.md/45eWjOZ
Feed: "MedCity News"
By: Frank Vinluan on Tuesday, August 5, 2025
By: Frank Vinluan on Tuesday, August 5, 2025
Vertex Non-Opioid Pain Drug Flunks Proof-of-Concept Test, Ending Plans for a Pivotal Study
A next-generation Vertex Pharmaceuticals pain drug failed to beat a placebo in a Phase 2 clinical trial. Despite the disappointing outcome in bunionectomy pain, the company is continuing development of the oral drug in diabetic peripheral neuropathy.
medcitynews.com
August 6, 2025 at 12:19 AM
Feed: "MedCity News"
By: Frank Vinluan on Tuesday, August 5, 2025
By: Frank Vinluan on Tuesday, August 5, 2025
Nav1.8 knock down had no influence on a preclinical post surgical model (but worked for inflammatory and NP). The therapeutic effect of Suzetrigine was pretty small for both bunionectomy and abdominoplasty. PK may explain the failure of VX-993. But I am still thinking indication.
August 5, 2025 at 4:34 PM
Nav1.8 knock down had no influence on a preclinical post surgical model (but worked for inflammatory and NP). The therapeutic effect of Suzetrigine was pretty small for both bunionectomy and abdominoplasty. PK may explain the failure of VX-993. But I am still thinking indication.
"Vertex Non-Opioid Pain Drug Flunks Proof-of-Concept Test, Ending Plans for a Pivotal Study"
#Caregiving #Healthcare #ElderCare #MedSky
#Caregiving #Healthcare #ElderCare #MedSky
Vertex Non-Opioid Pain Drug Flunks Proof-of-Concept Test, Ending Plans for a Pivotal Study
A next-generation Vertex Pharmaceuticals pain drug failed to beat a placebo in a Phase 2 clinical trial. Despite the disappointing outcome in bunionectomy pain, the company is continuing development of the oral drug in diabetic peripheral neuropathy.
The post Vertex Non-Opioid Pain Drug Flunks Proof-of-Concept Test, Ending Plans for a Pivotal Study appeared first on MedCity News.
medcitynews.com
August 5, 2025 at 4:00 PM
"Vertex Non-Opioid Pain Drug Flunks Proof-of-Concept Test, Ending Plans for a Pivotal Study"
#Caregiving #Healthcare #ElderCare #MedSky
#Caregiving #Healthcare #ElderCare #MedSky
Maybe, Michael, but why would one Nav1.8 inhibitor work and another would not for the same indication? Maybe the wrong indication as the suzetrigine trials were a mix of postsurgical pain types and this was just bunionectomy, but I don't think that is a good explanation. More likely PK?
August 5, 2025 at 2:14 PM
Maybe, Michael, but why would one Nav1.8 inhibitor work and another would not for the same indication? Maybe the wrong indication as the suzetrigine trials were a mix of postsurgical pain types and this was just bunionectomy, but I don't think that is a good explanation. More likely PK?