Carbonyl–olefin and carbonyl–alkyne metathesis enable atom-economic C–C bond formation beyond classical olefin metathesis. This review highlights recent advances in photochemical, Lewis-acid, Brønste...

npj Climate and Atmospheric Science - Carbon uptake of an urban green space inferred from carbonyl sulfide fluxes

Among the atmospheric gases that have been proposed as possible biosignatures in exoplanetary atmospheres, organosulfur gases are currently considered one of the more robust indicators of extant life....

Herein, we introduce a new platform for alkene carboxy-alkylation. This reaction is designed around CO2•– addition to alkenes followed by radical polar crossover, which enables alkylation through carbanion attack on carbonyl electrophiles. We discovered that CO2•– adds to alkenes faster than it reduces carbonyl electrophiles and that this reactivity can be exploited by accessing CO2•– via hydrogen atom transfer from formate. This photocatalytic system transforms vinylarenes and carbonyl compounds into a diverse array of substituted γ-lactone products. Furthermore, indoles can be engaged through dearomative carboxy-alkylation, delivering medicinally relevant C(sp3)-rich heterocyclic scaffolds. Mechanistic studies reveal that the active photocatalyst is generated in situ through a photochemically induced reaction between the precatalyst and DMSO. Overall, we have developed a three-component alkene carboxy-alkylation reaction enabled by the use of formate as the CO2•– precursor.

In contrast to transition elements, s- and p-block metal compounds that coordinate carbon monoxide (CO) under near-ambient conditions are elusive. Here, we report an isolable, crystalline main-group m...

Nature Chemistry, Published online: 18 August 2026; doi:10.1038/s41557-026-02231-5The α-arylation of carbonyl compounds remains a central challenge in chemical synthesis. Now it has been shown that BisTrip, a recyclable aryl group transporter, enables rapid and regiospecific α-arylation of diverse carbonyl compounds, providing access to challenging arylated ketones including quaternary carbon centres within intricate molecules.

[ACS Central Science] Complex organic molecules in interstellar ices and carbonaceous asteroids record key steps in the chemical evolution toward life, yet the origin of branched carbonyl compounds a ...

'Metallic' odors attributed to iron are due to organic carbonyl and organophosphine compounds