We’re excited to revisit the 2021 Albert Lasker Basic Medical Research Award: doi.org/10.1172/JCI1...
“My plan was to purify the rhodopsin from this Chlamydomonas creature, and I thought I could do it in a year. But it took me 15 years, actually.”—Peter Hegemann
“My plan was to purify the rhodopsin from this Chlamydomonas creature, and I thought I could do it in a year. But it took me 15 years, actually.”—Peter Hegemann
JCI - Karl Deisseroth, Peter Hegemann, and Dieter Oesterhelt receive the 2021 Albert Lasker Basic Medical Research Award
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doi.org
October 7, 2026 at 8:10 PM
We’re excited to revisit the 2021 Albert Lasker Basic Medical Research Award: doi.org/10.1172/JCI1...
“My plan was to purify the rhodopsin from this Chlamydomonas creature, and I thought I could do it in a year. But it took me 15 years, actually.”—Peter Hegemann
“My plan was to purify the rhodopsin from this Chlamydomonas creature, and I thought I could do it in a year. But it took me 15 years, actually.”—Peter Hegemann
https://theconversation.com/dune-algue-au-cerveau-letonnante-histoire-du-nobel-de-medecine-2026-293723
"comment Chlamydomonas fait-elle pour nager vers la lumière ? Cette question n’avait aucune application pratique évidente. Elle ne comblait aucun besoin urgent en matière de santé humaine et […]
"comment Chlamydomonas fait-elle pour nager vers la lumière ? Cette question n’avait aucune application pratique évidente. Elle ne comblait aucun besoin urgent en matière de santé humaine et […]
Original post on ecoevo.social
ecoevo.social
October 6, 2026 at 4:55 PM
https://theconversation.com/dune-algue-au-cerveau-letonnante-histoire-du-nobel-de-medecine-2026-293723
"comment Chlamydomonas fait-elle pour nager vers la lumière ? Cette question n’avait aucune application pratique évidente. Elle ne comblait aucun besoin urgent en matière de santé humaine et […]
"comment Chlamydomonas fait-elle pour nager vers la lumière ? Cette question n’avait aucune application pratique évidente. Elle ne comblait aucun besoin urgent en matière de santé humaine et […]
Why the Nobel Prize in Medicine 2026 matters: optogenetics controls brain cells with light and has already restored partial sight to a blind patient.
#nobelprize #medicine #technology #science @nobelprize.org
Click here to read the full story: theprobe.in/science-tech...
#nobelprize #medicine #technology #science @nobelprize.org
Click here to read the full story: theprobe.in/science-tech...
October 6, 2026 at 3:46 PM
Why the Nobel Prize in Medicine 2026 matters: optogenetics controls brain cells with light and has already restored partial sight to a blind patient.
#nobelprize #medicine #technology #science @nobelprize.org
Click here to read the full story: theprobe.in/science-tech...
#nobelprize #medicine #technology #science @nobelprize.org
Click here to read the full story: theprobe.in/science-tech...
Hoping for Chlamydomonas derived physics
October 6, 2026 at 9:22 AM
Hoping for Chlamydomonas derived physics
🎉 Wir gratulieren Prof. Dr. Peter Hegemann zum Nobelpreis für Medizin 2026 👏
Peter Hegemann forschte und lehrte von 1993 bis 2004 an der Uni Regensburg und legte mit seinen Arbeiten zur molekularen Photobiologie von Chlamydomonas das Fundament für die Entdeckung der Kanalrhodopsine.
Peter Hegemann forschte und lehrte von 1993 bis 2004 an der Uni Regensburg und legte mit seinen Arbeiten zur molekularen Photobiologie von Chlamydomonas das Fundament für die Entdeckung der Kanalrhodopsine.
October 6, 2026 at 8:55 AM
🎉 Wir gratulieren Prof. Dr. Peter Hegemann zum Nobelpreis für Medizin 2026 👏
Peter Hegemann forschte und lehrte von 1993 bis 2004 an der Uni Regensburg und legte mit seinen Arbeiten zur molekularen Photobiologie von Chlamydomonas das Fundament für die Entdeckung der Kanalrhodopsine.
Peter Hegemann forschte und lehrte von 1993 bis 2004 an der Uni Regensburg und legte mit seinen Arbeiten zur molekularen Photobiologie von Chlamydomonas das Fundament für die Entdeckung der Kanalrhodopsine.
Nadie buscaba una herramienta para la neurociencia. Solo se preguntaban cómo una alga unicelular, Chlamydomonas, sabe hacia dónde está la luz. 🌿💙
La respuesta fue un canal iónico que se abre con luz azul… y hoy permite encender neuronas
De un estanque a Estocolmo.
La respuesta fue un canal iónico que se abre con luz azul… y hoy permite encender neuronas
De un estanque a Estocolmo.
Nobel Prize in Physiology or Medicine 2026
The Nobel Prize in Physiology or Medicine 2026 was awarded jointly to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
www.nobelprize.org
October 5, 2026 at 6:48 PM
Nadie buscaba una herramienta para la neurociencia. Solo se preguntaban cómo una alga unicelular, Chlamydomonas, sabe hacia dónde está la luz. 🌿💙
La respuesta fue un canal iónico que se abre con luz azul… y hoy permite encender neuronas
De un estanque a Estocolmo.
La respuesta fue un canal iónico que se abre con luz azul… y hoy permite encender neuronas
De un estanque a Estocolmo.
Fantastic to see the Nobel Prize awarded for the discovery of channelrhodopsin which arose from Peter Hegemann's studies of algal motility. Here is a Chlamydomonas cell celebrating with some flagella calcium signals!
October 5, 2026 at 6:06 PM
Fantastic to see the Nobel Prize awarded for the discovery of channelrhodopsin which arose from Peter Hegemann's studies of algal motility. Here is a Chlamydomonas cell celebrating with some flagella calcium signals!
Congratulations to Chlamydomonas for winning the 2026 Nobel Prize!!
Apparently, there were also some human scientists (Karl Deisseroth, Peter Hegemann, and Georg Nagel) involved and congratulations to them as well;)
Yay Protistology!
Apparently, there were also some human scientists (Karl Deisseroth, Peter Hegemann, and Georg Nagel) involved and congratulations to them as well;)
Yay Protistology!
October 5, 2026 at 5:07 PM
Congratulations to Chlamydomonas for winning the 2026 Nobel Prize!!
Apparently, there were also some human scientists (Karl Deisseroth, Peter Hegemann, and Georg Nagel) involved and congratulations to them as well;)
Yay Protistology!
Apparently, there were also some human scientists (Karl Deisseroth, Peter Hegemann, and Georg Nagel) involved and congratulations to them as well;)
Yay Protistology!
Still celebrating today's Nobel-winning role for Chlamydomonas research, I highlight new, exciting Chlamy discovery from the Lechtreck Lab @universityofga.bsky.social. There are different (maybe 9?) Polycystin complexes in flagellar subdomains involved in fast swimming!
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
PKD2-like proteins target Chlamydomonas PKD2 to distinct subciliary regions | PNAS
Many motile and sensory functions of cilia and flagella depend on the precise localization
of transmembrane proteins within the ciliary membrane. R...
www.pnas.org
October 5, 2026 at 4:19 PM
Still celebrating today's Nobel-winning role for Chlamydomonas research, I highlight new, exciting Chlamy discovery from the Lechtreck Lab @universityofga.bsky.social. There are different (maybe 9?) Polycystin complexes in flagellar subdomains involved in fast swimming!
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
I love the vision at the end of Nagel et al. Science 2002:
"the ability of ChR1 to mediate a large light-switched H+ conductance in oocytes holds promise for the use of ChR1 as a tool for measuring and/or manipulating electrical and proton gradients across cell membranes, simply by illumination."
"the ability of ChR1 to mediate a large light-switched H+ conductance in oocytes holds promise for the use of ChR1 as a tool for measuring and/or manipulating electrical and proton gradients across cell membranes, simply by illumination."
October 5, 2026 at 1:56 PM
I love the vision at the end of Nagel et al. Science 2002:
"the ability of ChR1 to mediate a large light-switched H+ conductance in oocytes holds promise for the use of ChR1 as a tool for measuring and/or manipulating electrical and proton gradients across cell membranes, simply by illumination."
"the ability of ChR1 to mediate a large light-switched H+ conductance in oocytes holds promise for the use of ChR1 as a tool for measuring and/or manipulating electrical and proton gradients across cell membranes, simply by illumination."
Como estudo de uma alga iluminou a visão sobre o nosso cérebro e rendeu um Prêmio Nobel
Como estudo de uma alga iluminou a visão sobre o nosso cérebro e rendeu um Prêmio Nobel
Rapidez com que a alga Chlamydomonas reage à luz ajudou pesquisadores a descobrirem como "ativar e desativar" áreas do cérebro
veja.abril.com.br
October 5, 2026 at 1:21 PM
Como estudo de uma alga iluminou a visão sobre o nosso cérebro e rendeu um Prêmio Nobel
It all began with Peter Hegemann’s curiosity. He wondered how Chlamydomonas, a single-celled alga, is able to swim towards a light source.
www.nobelprize.org/prizes/medic...
www.nobelprize.org/prizes/medic...
Nobel Prize in Physiology or Medicine 2026
The Nobel Prize in Physiology or Medicine 2026 was awarded jointly to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
www.nobelprize.org
October 5, 2026 at 12:14 PM
It all began with Peter Hegemann’s curiosity. He wondered how Chlamydomonas, a single-celled alga, is able to swim towards a light source.
www.nobelprize.org/prizes/medic...
www.nobelprize.org/prizes/medic...
🔍 Bu Ödülün Arka Planında Ne Var?
Georg Nagel ve Peter Hegemann yeşil alglerde (Chlamydomonas) ışığa tepki veren bir protein olan Channelrhodopsin-1'i keşfettiler. Bu protein, ışık düştüğünde iyon kanallarını açar.
Georg Nagel ve Peter Hegemann yeşil alglerde (Chlamydomonas) ışığa tepki veren bir protein olan Channelrhodopsin-1'i keşfettiler. Bu protein, ışık düştüğünde iyon kanallarını açar.
October 5, 2026 at 11:10 AM
🔍 Bu Ödülün Arka Planında Ne Var?
Georg Nagel ve Peter Hegemann yeşil alglerde (Chlamydomonas) ışığa tepki veren bir protein olan Channelrhodopsin-1'i keşfettiler. Bu protein, ışık düştüğünde iyon kanallarını açar.
Georg Nagel ve Peter Hegemann yeşil alglerde (Chlamydomonas) ışığa tepki veren bir protein olan Channelrhodopsin-1'i keşfettiler. Bu protein, ışık düştüğünde iyon kanallarını açar.
yes so happy for him!!! this is exactly why we do curiosity-driven science... #chlamydomonas #protistsonsky
Funders and universities are you watching...???
Funders and universities are you watching...???
Peter Hegemann and Georg Nagel – awarded the 2026 medicine prize – discovered a remarkable protein, channelrhodopsin, in a single-celled alga.
Hegemann wondered how Chlamydomonas, a single-celled alga, is able to swim towards a light source.
Hegemann wondered how Chlamydomonas, a single-celled alga, is able to swim towards a light source.
October 5, 2026 at 11:02 AM
yes so happy for him!!! this is exactly why we do curiosity-driven science... #chlamydomonas #protistsonsky
Funders and universities are you watching...???
Funders and universities are you watching...???
What a day for Chlamydomonas research!
BREAKING NEWS
The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
October 5, 2026 at 10:52 AM
What a day for Chlamydomonas research!
Nobel per la Medicina – Da un’alga che cerca la luce una risposta ai meccanismi del cervello. Cos’è la Chlamydomonas
Nobel per la Medicina - Da un'alga che cerca la luce una risposta ai meccanismi del cervello
Dalla scoperta di una proteina sensibile alla luce in un’alga unicellulare alla possibilità di controllare con la luce l’attività delle cellule nervose
www.ilfattoquotidiano.it
October 5, 2026 at 10:47 AM
Nobel per la Medicina – Da un’alga che cerca la luce una risposta ai meccanismi del cervello. Cos’è la Chlamydomonas
The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
Hegemann wondered how Chlamydomonas, a single-celled alga, is able to swim towards a…
Hegemann wondered how Chlamydomonas, a single-celled alga, is able to swim towards a…
October 5, 2026 at 10:44 AM
The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
Hegemann wondered how Chlamydomonas, a single-celled alga, is able to swim towards a…
Hegemann wondered how Chlamydomonas, a single-celled alga, is able to swim towards a…
Huge congratulations to all three Nobel Laureates, and especially Peter Hegemann! 👏
His seminal work on the green alga Chlamydomonas 🦠 laid the foundation for optogenetics. Thank you for putting Chlamy in the spotlight! ✨
Proof that groundbreaking discoveries don't always come from animal models! 🔬
His seminal work on the green alga Chlamydomonas 🦠 laid the foundation for optogenetics. Thank you for putting Chlamy in the spotlight! ✨
Proof that groundbreaking discoveries don't always come from animal models! 🔬
October 5, 2026 at 10:00 AM
Huge congratulations to all three Nobel Laureates, and especially Peter Hegemann! 👏
His seminal work on the green alga Chlamydomonas 🦠 laid the foundation for optogenetics. Thank you for putting Chlamy in the spotlight! ✨
Proof that groundbreaking discoveries don't always come from animal models! 🔬
His seminal work on the green alga Chlamydomonas 🦠 laid the foundation for optogenetics. Thank you for putting Chlamy in the spotlight! ✨
Proof that groundbreaking discoveries don't always come from animal models! 🔬
A glorious day for our mighty Chlamydomonas 💚 and, of course, an unforgettable one for the Nobel laureates. So richly deserved!
BREAKING NEWS
The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
The 2026 Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
October 5, 2026 at 9:46 AM
A glorious day for our mighty Chlamydomonas 💚 and, of course, an unforgettable one for the Nobel laureates. So richly deserved!
Peter Hegemann and Georg Nagel – awarded the 2026 medicine prize – discovered a remarkable protein, channelrhodopsin, in a single-celled alga.
Hegemann wondered how Chlamydomonas, a single-celled alga, is able to swim towards a light source.
Hegemann wondered how Chlamydomonas, a single-celled alga, is able to swim towards a light source.
October 5, 2026 at 9:44 AM
Peter Hegemann and Georg Nagel – awarded the 2026 medicine prize – discovered a remarkable protein, channelrhodopsin, in a single-celled alga.
Hegemann wondered how Chlamydomonas, a single-celled alga, is able to swim towards a light source.
Hegemann wondered how Chlamydomonas, a single-celled alga, is able to swim towards a light source.
Maximilian Kotz, Veikko F. Geyer, Benjamin M. Friedrich: Axonemal bending stiffness of $\mathit{Chlamydomonas}$ cilia implies single-motor forces above $5\,\mathrm{pN}$ https://arxiv.org/abs/2609.39562 https://arxiv.org/pdf/2609.39562 https://arxiv.org/html/2609.39562
October 1, 2026 at 6:56 AM
Maximilian Kotz, Veikko F. Geyer, Benjamin M. Friedrich: Axonemal bending stiffness of $\mathit{Chlamydomonas}$ cilia implies single-motor forces above $5\,\mathrm{pN}$ https://arxiv.org/abs/2609.39562 https://arxiv.org/pdf/2609.39562 https://arxiv.org/html/2609.39562
(BioRxiv All) Novel protein networks in motile cilia from human epithelial cells revealed by cryo-ET and proteomics analysis of cilia from PCD patients: In our past study on human cilia from primary ciliary dyskinesia (PCD) patients using cryo-electron tomography and mass… #BioRxiv #MassSpecRSS
Novel protein networks in motile cilia from human epithelial cells revealed by cryo-ET and proteomics analysis of cilia from PCD patients
In our past study on human cilia from primary ciliary dyskinesia (PCD) patients using cryo-electron tomography and mass spectrometry, defects in the DNAH5 gene were proven to cause the loss of the entire outer dynein arm along with other proteins. This phenomenon was not observed in the unicellular green alga Chlamydomonas. In this study, we examined the loss of ciliary components caused by defects in various genes, based on proteomic and structural analyses of motile cilia from multiple PCD patients. The absence of single outer arm dynein genes causes a loss or significant decrease in other inner and outer arm dyneins. Interestingly, some patients with outer dynein defects show decreased intraflagellar transport (IFT) proteins, suggesting an influence of cargo components or assembly on transport. These phenomena were not observed in Chlamydomonas, suggesting a more complex mechanism of ciliogenesis in humans despite the high similarity in the final 3D architecture of the 9+2 axoneme. Defects in certain central pair proteins unexpectedly reduced components on the doublets as well. Our results demonstrate protein-protein interactions during stages of human motile ciliogenesis that are more complex than those in unicellular organisms.
dlvr.it
September 29, 2026 at 4:06 PM
(BioRxiv All) Novel protein networks in motile cilia from human epithelial cells revealed by cryo-ET and proteomics analysis of cilia from PCD patients: In our past study on human cilia from primary ciliary dyskinesia (PCD) patients using cryo-electron tomography and mass… #BioRxiv #MassSpecRSS
Axel finishes by bioconversion of natural products and how such process alters the bioactivity, while some activities are reduced (e.g. fungal BGC are not awaken), other activities of the natural product are gained (Chlamydomonas multicellularity)
#MibiNet
#MibiNet
September 29, 2026 at 1:02 PM
Axel finishes by bioconversion of natural products and how such process alters the bioactivity, while some activities are reduced (e.g. fungal BGC are not awaken), other activities of the natural product are gained (Chlamydomonas multicellularity)
#MibiNet
#MibiNet