🚀 FaceBase is now on BlueSky!

We are a public, NIDCR-funded data repository and resource driving innovation in dental, oral, & craniofacial (DOC) research.
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#CraniofacialDevelopment #Genomics #BiomedicalResearch #Bioinformatics

Scientists studied stem cells from Coffin-Siris syndrome patients and used animal models (mice and chicken embryos) to uncover how ZIC2 regulates neural crest cell migration and how ARID1A loss leads to craniofacial defects.
#CraniofacialDevelopment #Genetics

New Publication:
Neanderthal-derived variants increase SOX9 enhancer activity in craniofacial progenitors that shape jaw development

@uoe-igc.bsky.social @kirstyuttley.bsky.social @hannahlong.bsky.social

#neanderthalvariants #craniofacialdevelopment

journals.biologists.com/dev/article/...

In March's #EditorsChoice, Griffin, Saint-Jeannet & co come face to face with a new #Xenopus model for a rare #SplicingDisorder
⚡ doi.org/10.1242/dmm....
📰 doi.org/10.1242/dmm....
#CraniofacialDevelopment

Ancient genetics shape modern human traits. 🦧🧬Check out the latest #Refereedpreprint at @reviewcommons.org from the Long lab ‪on #Neanderthal variants influencing #craniofacialdevelopment
@hannahlong.bsky.social

Referee reports and author's response
>> eeb.embo.org/doi/10.1101/2024.09.24.614243

Cell Cycle Arrest of a "Zippering" Epithelial Cell Cluster Shapes the Face and is Disrupted in Craniofacial Disorders
Adameyko, I., Chacon, B. H. et al.
Paper
Details
#CellCycleArrest #CraniofacialDevelopment #EpithelialClusteringDisorders