And related to that, #CryoLithe is a pre-trained neural network replacing the backprojection operator to reconstruct high-quality denoised tomograms blazing fast – also a great collab with Vinith Kishore and Valentin Debarnot from the @ivandokmanic.bsky.social 🤓
Efficient reconstruction and denoising of cryo-ET data with end-to-end localized deep learning
Cryo-electron tomography (cryo-ET) enables 3D visualization of cellular structures. Accurate reconstruction of high-resolution volumes is complicated by the very low signal-to-noise ratio and a restri...
arxiv.org
January 9, 2026 at 7:15 PM
And related to that, #CryoLithe is a pre-trained neural network replacing the backprojection operator to reconstruct high-quality denoised tomograms blazing fast – also a great collab with Vinith Kishore and Valentin Debarnot from the @ivandokmanic.bsky.social 🤓
Our colleagues Vinith Kishore and Valentin Debarnot from the @ivandokmanic.bsky.social lab have come up with an amazing deep learning tool for denoising and filling the missing wedge in #cryoET data. I'm pleased to introduce Icecream🍧
Icecream: High-Fidelity Equivariant Cryo-Electron Tomography
Cryo-electron tomography (cryo-ET) visualizes 3D cellular architecture in near-native states. Recent deep-learning methods (CryoCARE, IsoNet, DeepDeWedge, CryoLithe) improve denoising and artifact cor...
www.biorxiv.org
October 23, 2025 at 11:13 AM
Our colleagues Vinith Kishore and Valentin Debarnot from the @ivandokmanic.bsky.social lab have come up with an amazing deep learning tool for denoising and filling the missing wedge in #cryoET data. I'm pleased to introduce Icecream🍧
[1/3] Le film "Greenland’s White Gold" accuse le Dk d’avoir tiré 400 milliards de couronnes du #cryolithe extrait à Ivittuut. Ce rappel du passé colonial a marqué les esprits au Groenland où un 1/3 des électeurs affirment avoir été influencés par le documentaire. #geography #Greenland #Documentary
Greenland documentary forces Danes to confront their colonial heritage
As Donald Trump threatens to take over the territory, film claims its cryolite mine was plundered by Denmark
www.theguardian.com
April 13, 2025 at 6:20 AM
[1/3] Le film "Greenland’s White Gold" accuse le Dk d’avoir tiré 400 milliards de couronnes du #cryolithe extrait à Ivittuut. Ce rappel du passé colonial a marqué les esprits au Groenland où un 1/3 des électeurs affirment avoir été influencés par le documentaire. #geography #Greenland #Documentary
I have been using CryoLithe recently as DeepDeWedge and cryoCARE erase many of the periplasmic complexes that I want to pick.
arxiv.org/abs/2501.15246
If you are unfortunate and have to manually pick particles. I have had the most success using the WARP deconvolution filter.
arxiv.org/abs/2501.15246
If you are unfortunate and have to manually pick particles. I have had the most success using the WARP deconvolution filter.
End-to-end localized deep learning for Cryo-ET
Cryo-electron tomography (cryo-ET) enables 3D visualization of cellular environments. Accurate reconstruction of high-resolution volumes is complicated by the very low signal-to-noise ratio and a rest...
arxiv.org
July 11, 2025 at 12:01 AM
I have been using CryoLithe recently as DeepDeWedge and cryoCARE erase many of the periplasmic complexes that I want to pick.
arxiv.org/abs/2501.15246
If you are unfortunate and have to manually pick particles. I have had the most success using the WARP deconvolution filter.
arxiv.org/abs/2501.15246
If you are unfortunate and have to manually pick particles. I have had the most success using the WARP deconvolution filter.
Technical Notes: March's software push includes updates to AlphaPulldown, AreTomo, Coot, CCP4, CryoLithe, DIALS, Doppio, Java, MPicker, OpenFreeEenergy, Open Force Field, qfit, SAMtools, Schrodinger, Scipion, and Xmipp.
More here: buff.ly/WXLwT6q
#SBGrid #Software #StructuralBiology
More here: buff.ly/WXLwT6q
#SBGrid #Software #StructuralBiology
SBGrid Consortium - Software Updates
The SBGrid Consortium is an innovative global research computing group operated out of Harvard Medical School. SBGrid provides the global structural biology community with support for research…
buff.ly
April 6, 2026 at 4:03 PM
Technical Notes: March's software push includes updates to AlphaPulldown, AreTomo, Coot, CCP4, CryoLithe, DIALS, Doppio, Java, MPicker, OpenFreeEenergy, Open Force Field, qfit, SAMtools, Schrodinger, Scipion, and Xmipp.
More here: buff.ly/WXLwT6q
#SBGrid #Software #StructuralBiology
More here: buff.ly/WXLwT6q
#SBGrid #Software #StructuralBiology
New Title Alert: CryoLithe- a supervised machine learning method to directly reconstruct the tomogram from aligned cryo-ET tilt series. The methods is trained on real measurements using FBP+cryo-CARE+IsoNet reconstructions as the reference.
Learn more here: buff.ly/3jxoax3
#SBGrid #Software
Learn more here: buff.ly/3jxoax3
#SBGrid #Software
GitHub - swing-research/CryoLithe
Contribute to swing-research/CryoLithe development by creating an account on GitHub.
github.com
December 16, 2025 at 5:04 PM
New Title Alert: CryoLithe- a supervised machine learning method to directly reconstruct the tomogram from aligned cryo-ET tilt series. The methods is trained on real measurements using FBP+cryo-CARE+IsoNet reconstructions as the reference.
Learn more here: buff.ly/3jxoax3
#SBGrid #Software
Learn more here: buff.ly/3jxoax3
#SBGrid #Software