CCC Tournament quarterfinals begin Thursday in boys soccer, girls soccer and field hockey collinsvillepress.com/2026/10/2026... #ctfh #ctbsoc #ctgsoc
2026 CCC fall championships
2026 Central Connecticut Conference fall championship tournaments. Seeds and league records from the CCC website. Overall records from the CIAC website as reported by respective schools. BOYS SOCCER T...
collinsvillepress.com
October 28, 2026 at 11:16 PM
CCC Tournament quarterfinals begin Thursday in boys soccer, girls soccer and field hockey collinsvillepress.com/2026/10/2026... #ctfh #ctbsoc #ctgsoc
Second, we investigated the phenotype of cTfh and cTph using flow cytometry and single cell omics. We confirm previous studies that blood CXCR5-PD1hi (cTph) and CXCR5+PD1hi (cTfh) cells share B-cell helper features. However, no phenotypic changes are seen in T1D, just an increase in frequency.
June 24, 2025 at 7:50 AM
Second, we investigated the phenotype of cTfh and cTph using flow cytometry and single cell omics. We confirm previous studies that blood CXCR5-PD1hi (cTph) and CXCR5+PD1hi (cTfh) cells share B-cell helper features. However, no phenotypic changes are seen in T1D, just an increase in frequency.
It turns out that no changes are seen at this point, only later, i.e. a few years before clinical disease onset, and more dominantly for cTph than cTfh cells, suggesting that the increase of these cells in blood is associated with disease progression and hypothetically ectopic lymphoid structures.
June 24, 2025 at 7:50 AM
It turns out that no changes are seen at this point, only later, i.e. a few years before clinical disease onset, and more dominantly for cTph than cTfh cells, suggesting that the increase of these cells in blood is associated with disease progression and hypothetically ectopic lymphoid structures.
Here, we addressed a few outstanding questions. First: what is the exact timing of cTfh and cTph increase during the disease process? For this, we analysed rare samples collected at the time of seroconversion, i.e. the earliest detectable time point of autoimmunity.
June 24, 2025 at 7:50 AM
Here, we addressed a few outstanding questions. First: what is the exact timing of cTfh and cTph increase during the disease process? For this, we analysed rare samples collected at the time of seroconversion, i.e. the earliest detectable time point of autoimmunity.
This study complements our earlier studies on the role of these "B-cell helper" T cells in T1D, where we have shown that both cTfh and cTph are increased in the blood of children with newly diagnosed T1D and also in prediabetic autoantibody-positive (AAb+) children.
June 24, 2025 at 7:50 AM
This study complements our earlier studies on the role of these "B-cell helper" T cells in T1D, where we have shown that both cTfh and cTph are increased in the blood of children with newly diagnosed T1D and also in prediabetic autoantibody-positive (AAb+) children.
New results on the role of circulating T follicular (cTfh) and T peripheral helper (cTph) cells in type 1 diabetes out at @eurjimmunol.bsky.social: onlinelibrary.wiley.com/doi/10.1002/...
#immunosky #T1D #autoimmunity
#immunosky #T1D #autoimmunity
The Frequency but not the Phenotype of Circulating Peripheral T Helper Cells is Increased at Later Stages of Progression to Type 1 Diabetes
Frequencies of circulating T peripheral helper (cTph) and activated T follicular helper (cTfh) cells increase close to the diagnosis of clinical type 1 diabetes, but not at the onset of autoimmunity.....
onlinelibrary.wiley.com
June 24, 2025 at 7:50 AM
New results on the role of circulating T follicular (cTfh) and T peripheral helper (cTph) cells in type 1 diabetes out at @eurjimmunol.bsky.social: onlinelibrary.wiley.com/doi/10.1002/...
#immunosky #T1D #autoimmunity
#immunosky #T1D #autoimmunity
I've hyper-focused onto an LA --> DFW Amtrak trip in a sleeper car. 😆 Meals included and two days of solitude? Sounds like the perfect opportunity to center myself like I did last year - www.youtube.com/watch?v=cTFh... - while doing some good reading. 😍
Also to see people and eat food. ❤️ Make me! 😆
Also to see people and eat food. ❤️ Make me! 😆
January 20, 2025 at 12:18 AM
I've hyper-focused onto an LA --> DFW Amtrak trip in a sleeper car. 😆 Meals included and two days of solitude? Sounds like the perfect opportunity to center myself like I did last year - www.youtube.com/watch?v=cTFh... - while doing some good reading. 😍
Also to see people and eat food. ❤️ Make me! 😆
Also to see people and eat food. ❤️ Make me! 😆
It's late and I'm thinking: LA to Dallas on Amtrak is 40 hours. I'd go with the Roomette and spend the entire time reading, writing, and just hanging out.
Every now and then, I take solo trips (sometimes with friends). The last time I did that, it was to SF - www.youtube.com/watch?v=cTFh...
Every now and then, I take solo trips (sometimes with friends). The last time I did that, it was to SF - www.youtube.com/watch?v=cTFh...
October 22, 2024 at 6:08 AM
It's late and I'm thinking: LA to Dallas on Amtrak is 40 hours. I'd go with the Roomette and spend the entire time reading, writing, and just hanging out.
Every now and then, I take solo trips (sometimes with friends). The last time I did that, it was to SF - www.youtube.com/watch?v=cTFh...
Every now and then, I take solo trips (sometimes with friends). The last time I did that, it was to SF - www.youtube.com/watch?v=cTFh...
Richard loves snow days...
youtube.com/shorts/CtFh-...
youtube.com/shorts/CtFh-...
Does your dog make snowballs? #dogs #winter #snow
YouTube video by Jamie
youtube.com
December 20, 2024 at 5:18 PM
Richard loves snow days...
youtube.com/shorts/CtFh-...
youtube.com/shorts/CtFh-...
cTfh Cell Activation and Changes in BTLA and LAG-3 Expression Differentially Associate With Poor Pregnancy Outcome in Plasmodium falciparum Placental Malaria PubMed
cTfh Cell Activation and Changes in BTLA and LAG-3 Expression Differentially Associate With Poor Pregnancy Outcome in Plasmodium falciparum Placental Malaria
Continuous exposure to antigens drives the activation of circulating T follicular helper (cTfh) cells, promoting high-affinity antibody production. However, sustained stimulation may impair their function through the upregulation of immunoregulatory markers like B and T lymphocyte attenuator (BTLA) and Lymphocyte-activation gene 3 (LAG-3). This study investigated the role of cTfh cells and their subsets in Plasmodium falciparum-associated placental malaria (PM). In a cross-sectional study...
dlvr.it
April 16, 2026 at 10:31 AM
cTfh Cell Activation and Changes in BTLA and LAG-3 Expression Differentially Associate With Poor Pregnancy Outcome in Plasmodium falciparum Placental Malaria PubMed
Most interesting to me was the peculiar nature of the antibody response in the PASC group. First, unlike in the CONV (control) group, antibody (Ab) levels did not significantly wane over time in the PASC group. High levels of circulating T follicular helper cells (cTFH)… 4/
September 2, 2025 at 3:16 AM
Most interesting to me was the peculiar nature of the antibody response in the PASC group. First, unlike in the CONV (control) group, antibody (Ab) levels did not significantly wane over time in the PASC group. High levels of circulating T follicular helper cells (cTFH)… 4/
Elle allume une cigarette, son appareil respiratoire prend feu : un Ehpad entier évacué | Courrier de l'Ouest
➡️ https://l.ouest-france.fr/cTFH
➡️ https://l.ouest-france.fr/cTFH
September 16, 2025 at 5:43 PM
Elle allume une cigarette, son appareil respiratoire prend feu : un Ehpad entier évacué | Courrier de l'Ouest
➡️ https://l.ouest-france.fr/cTFH
➡️ https://l.ouest-france.fr/cTFH
"Rapid and robust antibody and coordinated B-cell and cTfh responses were induced by vaccination, resulting in successful viral clearance. Furthermore, vaccine-elicited antibodies exhibited neutralizing activities against various VOCs and persisted for over 6 months."
December 26, 2024 at 2:31 AM
"Rapid and robust antibody and coordinated B-cell and cTfh responses were induced by vaccination, resulting in successful viral clearance. Furthermore, vaccine-elicited antibodies exhibited neutralizing activities against various VOCs and persisted for over 6 months."
"All cases were young adults without immunodeficiency,but exhibited impaired immune activation against SARS-CoV-2,as indicated by lower levels of inflammation,interferon responses,antibody responses,specific CD4+ and CD8+ T-cell responses,as well as circulating follicular helper T cells (cTfh). /3
December 26, 2024 at 2:29 AM
"All cases were young adults without immunodeficiency,but exhibited impaired immune activation against SARS-CoV-2,as indicated by lower levels of inflammation,interferon responses,antibody responses,specific CD4+ and CD8+ T-cell responses,as well as circulating follicular helper T cells (cTfh). /3
Feed: "JCI Insight -- New Articles"
By: Vera Kim, Takaya Misao, Hong Tian, Meggan Mackay, Cynthia Aranow, Sun Jung Kim
By: Vera Kim, Takaya Misao, Hong Tian, Meggan Mackay, Cynthia Aranow, Sun Jung Kim
Metabolic pathways within cTfh subsets and glucose-dependent activation of cTfh17 in SLE and healthy individuals
Cellular metabolism plays a key role in T cell biology. Increased glycolysis and mitochondrial respiration have been identified in CD4+ helper T cells from both patients with systemic lupus erythematosus (SLE) and lupus mouse models. Inhibiting this metabolic activity can reduce T cell activation and ameliorate disease symptoms in lupus mice. However, the metabolic differences among circulating follicular helper T (cTfh) cell subsets in patients with SLE versus healthy controls (HCs) have not been thoroughly studied. While the frequencies of cTfh cells and their subsets were similar between patients with SLE and HCs, patients exhibited a higher proportion of activated ICOS+ programmed cell death 1–positive cells, which correlated with disease activity. cTfh17 cells from both patients with SLE and HCs demonstrated heightened glycolytic activity and expression of glycolysis-related genes compared with cTfh1 and cTfh2. Glucose deprivation significantly diminished costimulatory molecule expression and cytokine production, including IL-17A, IL-10, IL-2, and TNF-α. Glycolysis inhibition reduced the B cell activation capacity of cTfh17 cells. This glucose dependence was more pronounced in cTfh17 than cTfh2 from patients with SLE, but it similarly affected both cTfh2 and cTfh17 cells from HCs. These findings highlight distinct metabolic dependencies among cTfh subsets and the critical role of glycolysis in cTfh17-mediated B cell activation in SLE.
insight.jci.org
July 24, 2025 at 11:25 PM
Feed: "JCI Insight -- New Articles"
By: Vera Kim, Takaya Misao, Hong Tian, Meggan Mackay, Cynthia Aranow, Sun Jung Kim
By: Vera Kim, Takaya Misao, Hong Tian, Meggan Mackay, Cynthia Aranow, Sun Jung Kim
So unrelated to #Pride I fell down a rabbithole and...
On a scale from Gay to #LadyGaga, is this a #LindseyGraham? #BadRomance
www.youtube.com/watch?v=cTFh...
On a scale from Gay to #LadyGaga, is this a #LindseyGraham? #BadRomance
www.youtube.com/watch?v=cTFh...
On the Rocks - Lady Gaga - Bad Romance
YouTube video by Leo da Silva
www.youtube.com
June 2, 2025 at 9:39 AM
So unrelated to #Pride I fell down a rabbithole and...
On a scale from Gay to #LadyGaga, is this a #LindseyGraham? #BadRomance
www.youtube.com/watch?v=cTFh...
On a scale from Gay to #LadyGaga, is this a #LindseyGraham? #BadRomance
www.youtube.com/watch?v=cTFh...
What is concerning regarding the read out system used is that in subjects infected with SARDS-CoV-2 the authors find a reduced anti-Spike response. This is the oposite of what is expected and found by many others. www.nature.com/articles/s41...
Establishment and recall of SARS-CoV-2 spike epitope-specific CD4+ T cell memory - Nature Immunology
Wragg and colleagues use MHC class II tetramers and TCRβ sequencing to track clonal populations of spike-specific CD4+ cTFH cells from cohorts of convalescent individuals with coronavirus disease 2019...
www.nature.com
December 4, 2025 at 3:39 PM
What is concerning regarding the read out system used is that in subjects infected with SARDS-CoV-2 the authors find a reduced anti-Spike response. This is the oposite of what is expected and found by many others. www.nature.com/articles/s41...
Here's a new co-authored pre-print with Michelle Boyle @burnetinstitute.bsky.social, studying cTfh cells in volunteers infected with P. falciparum, via scRNA-seq and paired TCR-seq. Tfh1 are split based on CCR7, with CCR7+ Tfh1 correlating with antibody responses.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
March 3, 2025 at 9:48 AM
Here's a new co-authored pre-print with Michelle Boyle @burnetinstitute.bsky.social, studying cTfh cells in volunteers infected with P. falciparum, via scRNA-seq and paired TCR-seq. Tfh1 are split based on CCR7, with CCR7+ Tfh1 correlating with antibody responses.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Covers Project v2 Day 160: I know the words "College acapella band" don't inspire much confidence, but this cover from On The Rocks, a group originally started by YouTuber Peter Hollens, is actually really awesome
www.youtube.com/watch?v=cTFh...
www.youtube.com/watch?v=cTFh...
On the Rocks - Lady Gaga - Bad Romance
YouTube video by Leo da Silva
www.youtube.com
June 10, 2026 at 1:44 PM
Covers Project v2 Day 160: I know the words "College acapella band" don't inspire much confidence, but this cover from On The Rocks, a group originally started by YouTuber Peter Hollens, is actually really awesome
www.youtube.com/watch?v=cTFh...
www.youtube.com/watch?v=cTFh...
こいつら最高でずっと仲間に入れてほしい。 www.youtube.com/watch?v=ctFH...
【爆食】夢の3kg超え！超特大チーズバーガーを一から手作りしたらうますぎた
YouTube video by ひみつ基地。
www.youtube.com
May 29, 2026 at 1:18 PM
こいつら最高でずっと仲間に入れてほしい。 www.youtube.com/watch?v=ctFH...
Emma Warren from Celtic Woman covered Kacey Musgraves’ Rainbow” for their 20th Anniversary album!! It sounds amazing!! 👏🏽🥹💃🏾🎶🌈
You can listen here: www.youtube.com/watch?v=CtFh...
You can listen here: www.youtube.com/watch?v=CtFh...
Rainbow (20th Anniversary)
Provided to YouTube by Universal Music GroupRainbow (20th Anniversary) · Celtic Woman20℗ Manhattan Records; ℗ 2024 Celtic Woman Limited, under exclusive lice...
www.youtube.com
January 26, 2024 at 4:46 PM
Emma Warren from Celtic Woman covered Kacey Musgraves’ Rainbow” for their 20th Anniversary album!! It sounds amazing!! 👏🏽🥹💃🏾🎶🌈
You can listen here: www.youtube.com/watch?v=CtFh...
You can listen here: www.youtube.com/watch?v=CtFh...
www.youtube.com/watch?v=CTFH...
Heya folks, here's a First 10 Minutes video featuring an indie arcade game called Ultratron by Puppygames.
#ultratron #videogames #retrogaming #indiegames #arcadegames #first10minutes #gameplay
Heya folks, here's a First 10 Minutes video featuring an indie arcade game called Ultratron by Puppygames.
#ultratron #videogames #retrogaming #indiegames #arcadegames #first10minutes #gameplay
Ultratron First 10 Minutes in 4K60 | Pure Robot Arcade Mayhem Gameplay
YouTube video by Daily Game Bytes Presents: The First 10 Minutes
www.youtube.com
June 18, 2026 at 12:10 PM
www.youtube.com/watch?v=CTFH...
Heya folks, here's a First 10 Minutes video featuring an indie arcade game called Ultratron by Puppygames.
#ultratron #videogames #retrogaming #indiegames #arcadegames #first10minutes #gameplay
Heya folks, here's a First 10 Minutes video featuring an indie arcade game called Ultratron by Puppygames.
#ultratron #videogames #retrogaming #indiegames #arcadegames #first10minutes #gameplay
Formation Bio Acquires Rights to Innovative Autoimmune Treatment from CTFH#USA#New_York#Formation_Bio#miR-124#CTFH
Formation Bio Acquires Rights to Innovative Autoimmune Treatment from CTFH
Formation Bio expands its portfolio with the acquisition of an innovative oral treatment for autoimmune diseases, enhancing patient care options.
third-news.com
January 29, 2026 at 2:39 PM
Formation Bio Acquires Rights to Innovative Autoimmune Treatment from CTFH#USA#New_York#Formation_Bio#miR-124#CTFH