July 4, 2025 at 7:37 PM
To all interested in all things related to Pulmonary Fibrosis - the #CureFibrosis starter pack is ready for 2025 - please let me know if you wish to be included and ofcourse follow - use #CurePF4All #CureIPF #CureFibrosis etc
#HappyNewYear
go.bsky.app/6hgNDdr
#HappyNewYear
go.bsky.app/6hgNDdr
December 26, 2024 at 6:05 PM
To all interested in all things related to Pulmonary Fibrosis - the #CureFibrosis starter pack is ready for 2025 - please let me know if you wish to be included and ofcourse follow - use #CurePF4All #CureIPF #CureFibrosis etc
#HappyNewYear
go.bsky.app/6hgNDdr
#HappyNewYear
go.bsky.app/6hgNDdr
Looks like telomere dysfunction is complex in mice and people
- needs more investigation and great science.
#Telomeres
#CureIPF
🧪
🧬
- needs more investigation and great science.
#Telomeres
#CureIPF
🧪
🧬
According to dogma mammalian telomeres shorten with age.
This paper shows that mouse telomeres do not shorten with age. Should we revisit the paradigm?
Kudos Drs Smoom, Tzfati & team!!!
#ScienceMattets
academic.oup.com/nar/article/...
This paper shows that mouse telomeres do not shorten with age. Should we revisit the paradigm?
Kudos Drs Smoom, Tzfati & team!!!
#ScienceMattets
academic.oup.com/nar/article/...
The house mouse maintains constant telomere length throughout life
Abstract. Telomeres protect the chromosome ends from deleterious DNA damage response and repair activities. In humans, telomerase maintains telomere length
academic.oup.com
August 31, 2025 at 4:58 PM
Looks like telomere dysfunction is complex in mice and people
- needs more investigation and great science.
#Telomeres
#CureIPF
🧪
🧬
- needs more investigation and great science.
#Telomeres
#CureIPF
🧪
🧬
Wow! What a day for #CureIPF & #ATS2025! First positive drug trial in 10 years in IPF!! Treatment with Nerandomilast -> ⬇️FVC decline compared to placebo in patients on antifibrotics or untreated. Kudos Drs Richeldi and Wijsenbeek and #FibroneerIPF team!!! www.nejm.org/doi/full/10....
May 19, 2025 at 4:26 AM
Wow! What a day for #CureIPF & #ATS2025! First positive drug trial in 10 years in IPF!! Treatment with Nerandomilast -> ⬇️FVC decline compared to placebo in patients on antifibrotics or untreated. Kudos Drs Richeldi and Wijsenbeek and #FibroneerIPF team!!! www.nejm.org/doi/full/10....
Fascinating work on the regulation of telomere length - molecular clocks we all have in our cells controlling aging and disease.
Emerging evidence of their role pulmonary fibrosis.
#CureIPF
#Telomeres
@elife.bsky.social
@rcsi.bsky.social
@kaminskimed.bsky.social
Emerging evidence of their role pulmonary fibrosis.
#CureIPF
#Telomeres
@elife.bsky.social
@rcsi.bsky.social
@kaminskimed.bsky.social
Your chromosomes have protective ends called telomeres. As they shorten, your cells age. This study reveals how a protein, TRF2, directly regulates telomerase activity to keep telomeres in check.
Keeping telomeres at the right length
The key telomere protein TRF2 helps regulate telomere length by interacting with the telomerase gene TERT in a length-dependent manner.
buff.ly
October 4, 2025 at 4:33 PM
Fascinating work on the regulation of telomere length - molecular clocks we all have in our cells controlling aging and disease.
Emerging evidence of their role pulmonary fibrosis.
#CureIPF
#Telomeres
@elife.bsky.social
@rcsi.bsky.social
@kaminskimed.bsky.social
Emerging evidence of their role pulmonary fibrosis.
#CureIPF
#Telomeres
@elife.bsky.social
@rcsi.bsky.social
@kaminskimed.bsky.social
The Impact of Pulmonary Fibrosis on Sex and Sexual Function - A Multinational Mixed Methods Study
Just out in ERJ and led by Dr. Na'ama Avitzur
A 🧵👇
(key take-away 👉 sex matters to patients with PF and their disease impacts this)
#OpenAccess #CurePF #CureIPF
publications.ersnet.org/content/erj/...
Just out in ERJ and led by Dr. Na'ama Avitzur
A 🧵👇
(key take-away 👉 sex matters to patients with PF and their disease impacts this)
#OpenAccess #CurePF #CureIPF
publications.ersnet.org/content/erj/...
October 14, 2025 at 1:59 AM
The Impact of Pulmonary Fibrosis on Sex and Sexual Function - A Multinational Mixed Methods Study
Just out in ERJ and led by Dr. Na'ama Avitzur
A 🧵👇
(key take-away 👉 sex matters to patients with PF and their disease impacts this)
#OpenAccess #CurePF #CureIPF
publications.ersnet.org/content/erj/...
Just out in ERJ and led by Dr. Na'ama Avitzur
A 🧵👇
(key take-away 👉 sex matters to patients with PF and their disease impacts this)
#OpenAccess #CurePF #CureIPF
publications.ersnet.org/content/erj/...
Just added this 👇🏼 to my #SpatialTranscriptomics and #CureIPF weekend reading lists - so should you
Delighted 2 share latest preprint evaluating fibrotic niche in #IPF using spatial transcriptomics & Hyperion mass cytometry. We believe it raises some interesting questions about IPF pathogenesis IPF.
@nebanovich.bsky.social @kaminskimed.bsky.social
www.biorxiv.org/content/10.1...
@nebanovich.bsky.social @kaminskimed.bsky.social
www.biorxiv.org/content/10.1...
Multiscale single-cell assessment of the fibrotic niche in idiopathic pulmonary fibrosis
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal disease characterized by excessive extracellular matrix deposition within the lung. Recent advances in single-cell ...
www.biorxiv.org
December 14, 2024 at 9:17 PM
Just added this 👇🏼 to my #SpatialTranscriptomics and #CureIPF weekend reading lists - so should you
Video explainer of the new Patient Stem Cell Discovery Core in RCSI @rcsi.bsky.social & Beaumont Hospital.
With patients like David Crosby we aim to find treatments for pulmonary fibrosis and cystic fibrosis.
🧪
#CureIPF
#iPSC
#CF
Supporting work by
@erc.europa.eu
@researchireland.bsky.social
HRB
With patients like David Crosby we aim to find treatments for pulmonary fibrosis and cystic fibrosis.
🧪
#CureIPF
#iPSC
#CF
Supporting work by
@erc.europa.eu
@researchireland.bsky.social
HRB
The new RCSI Patient Stem Cell Discovery Core is Ireland’s first dedicated patient stem cell research facility in our Education and Research Centre at Beaumont Hospital.
Learn more from Professor Killian Hurley and patient advocate David Crosby in the video below ⬇️
youtu.be/cg3fKicccTI
Learn more from Professor Killian Hurley and patient advocate David Crosby in the video below ⬇️
youtu.be/cg3fKicccTI
RCSI Patient Stem Cell Discovery Core
YouTube video by RCSI
youtu.be
April 16, 2025 at 4:58 PM
Video explainer of the new Patient Stem Cell Discovery Core in RCSI @rcsi.bsky.social & Beaumont Hospital.
With patients like David Crosby we aim to find treatments for pulmonary fibrosis and cystic fibrosis.
🧪
#CureIPF
#iPSC
#CF
Supporting work by
@erc.europa.eu
@researchireland.bsky.social
HRB
With patients like David Crosby we aim to find treatments for pulmonary fibrosis and cystic fibrosis.
🧪
#CureIPF
#iPSC
#CF
Supporting work by
@erc.europa.eu
@researchireland.bsky.social
HRB
Fantastic pulmonary fibrosis starter pack from @kaminskimed.bsky.social.
Thanks for putting this together Naftali and giving leadership in the field.
#CureIPF
#CureFibrosis
#IPF2025
Thanks for putting this together Naftali and giving leadership in the field.
#CureIPF
#CureFibrosis
#IPF2025
To all interested in all things related to Pulmonary Fibrosis - the #CureFibrosis starter pack is ready for 2025 - please let me know if you wish to be included and ofcourse follow - use #CurePF4All #CureIPF #CureFibrosis etc
#HappyNewYear
go.bsky.app/6hgNDdr
#HappyNewYear
go.bsky.app/6hgNDdr
December 26, 2024 at 7:56 PM
Fantastic pulmonary fibrosis starter pack from @kaminskimed.bsky.social.
Thanks for putting this together Naftali and giving leadership in the field.
#CureIPF
#CureFibrosis
#IPF2025
Thanks for putting this together Naftali and giving leadership in the field.
#CureIPF
#CureFibrosis
#IPF2025
If you had any doubt. Air pollution is bad - "Long-Term Air Pollution Exposure & Severity of Idiopathic Pulmonary Fibrosis: Data from the IPF-PRO Registry" - provides insights about #AirPollution and IPF. Kudos to Drs Sack, Gulati & IPF-PRO Team
#CureIPF
#CleanAir
www.atsjournals.org/doi/10.1513/...
#CureIPF
#CleanAir
www.atsjournals.org/doi/10.1513/...
November 19, 2024 at 1:01 PM
If you had any doubt. Air pollution is bad - "Long-Term Air Pollution Exposure & Severity of Idiopathic Pulmonary Fibrosis: Data from the IPF-PRO Registry" - provides insights about #AirPollution and IPF. Kudos to Drs Sack, Gulati & IPF-PRO Team
#CureIPF
#CleanAir
www.atsjournals.org/doi/10.1513/...
#CureIPF
#CleanAir
www.atsjournals.org/doi/10.1513/...
Kicking off my first day at #ATS2025 looking forward to catching up with the pulmonary fibrosis research community and hearing the latest data! 🫁 #cureIPF
@atscommunity.bsky.social
@atsearlycareer.bsky.social
@ats-rcmb.bsky.social
@atscommunity.bsky.social
@atsearlycareer.bsky.social
@ats-rcmb.bsky.social
May 18, 2025 at 4:01 PM
Kicking off my first day at #ATS2025 looking forward to catching up with the pulmonary fibrosis research community and hearing the latest data! 🫁 #cureIPF
@atscommunity.bsky.social
@atsearlycareer.bsky.social
@ats-rcmb.bsky.social
@atscommunity.bsky.social
@atsearlycareer.bsky.social
@ats-rcmb.bsky.social
The single cell observatory at the #KaminskiLab is now whole and complete; we have full single cell, biomarkers, & spatial capacities in our lab. And more importantly. As always, amazing lab members!!!
#AcademicBliss
Grateful to all our amazing partners and collaborators!!!
#TeamsMatter
#CureIPF
#AcademicBliss
Grateful to all our amazing partners and collaborators!!!
#TeamsMatter
#CureIPF
May 10, 2026 at 4:28 AM
The single cell observatory at the #KaminskiLab is now whole and complete; we have full single cell, biomarkers, & spatial capacities in our lab. And more importantly. As always, amazing lab members!!!
#AcademicBliss
Grateful to all our amazing partners and collaborators!!!
#TeamsMatter
#CureIPF
#AcademicBliss
Grateful to all our amazing partners and collaborators!!!
#TeamsMatter
#CureIPF
After a long time I remade my office Zoom background - and I really like it - especially the Texas #CureIPF license plate. And yes, one day we’ll get there!
#CurePF4All
#CurePF4All
March 3, 2026 at 2:20 AM
After a long time I remade my office Zoom background - and I really like it - especially the Texas #CureIPF license plate. And yes, one day we’ll get there!
#CurePF4All
#CurePF4All
Grateful for the invite to speak about the Cellular BluePrint of Pulmonary fibrosis and how we could use AI to develop novel approaches to #CureIPF
April 21, 2026 at 2:18 AM
Grateful for the invite to speak about the Cellular BluePrint of Pulmonary fibrosis and how we could use AI to develop novel approaches to #CureIPF
For the new BlueSky members who have left #ILDTwitter I’ve updated this starter-pack to help you find key ILD and ILD-adjacent community members here. Pls comment if I’ve missed you and I’ll add you 🫁😊
#CurePF #CureIPF #ILD
go.bsky.app/8u4KcNo
#CurePF #CureIPF #ILD
go.bsky.app/8u4KcNo
November 14, 2024 at 3:22 AM
For the new BlueSky members who have left #ILDTwitter I’ve updated this starter-pack to help you find key ILD and ILD-adjacent community members here. Pls comment if I’ve missed you and I’ll add you 🫁😊
#CurePF #CureIPF #ILD
go.bsky.app/8u4KcNo
#CurePF #CureIPF #ILD
go.bsky.app/8u4KcNo
Great work by Dr Aoife Carolan from our group at @rcsi.bsky.social
RCSI showing data from our familial pulmonary fibrosis clinic.
- 1 in 5 patients have a family memeber with lung fibrosis.
- 1 in 5 of these patients have a single suspected gene.
#CureIPF
@europeanrespsoc.bsky.social
RCSI showing data from our familial pulmonary fibrosis clinic.
- 1 in 5 patients have a family memeber with lung fibrosis.
- 1 in 5 of these patients have a single suspected gene.
#CureIPF
@europeanrespsoc.bsky.social
September 29, 2025 at 6:07 AM
Great work by Dr Aoife Carolan from our group at @rcsi.bsky.social
RCSI showing data from our familial pulmonary fibrosis clinic.
- 1 in 5 patients have a family memeber with lung fibrosis.
- 1 in 5 of these patients have a single suspected gene.
#CureIPF
@europeanrespsoc.bsky.social
RCSI showing data from our familial pulmonary fibrosis clinic.
- 1 in 5 patients have a family memeber with lung fibrosis.
- 1 in 5 of these patients have a single suspected gene.
#CureIPF
@europeanrespsoc.bsky.social
Now can we use CA-125 as a theragnostic biomarker of treatment response in patients with IPF? Why wouldn't we?
@ipfdoc.bsky.social @kaminskimed.bsky.social
#CurePF #CureIPF @ats-clinicalprobs.bsky.social @tkulkarni.bsky.social @jskim8223.bsky.social
pmc.ncbi.nlm.nih.gov/articles/pmi...
@ipfdoc.bsky.social @kaminskimed.bsky.social
#CurePF #CureIPF @ats-clinicalprobs.bsky.social @tkulkarni.bsky.social @jskim8223.bsky.social
pmc.ncbi.nlm.nih.gov/articles/pmi...
December 21, 2024 at 6:52 AM
Now can we use CA-125 as a theragnostic biomarker of treatment response in patients with IPF? Why wouldn't we?
@ipfdoc.bsky.social @kaminskimed.bsky.social
#CurePF #CureIPF @ats-clinicalprobs.bsky.social @tkulkarni.bsky.social @jskim8223.bsky.social
pmc.ncbi.nlm.nih.gov/articles/pmi...
@ipfdoc.bsky.social @kaminskimed.bsky.social
#CurePF #CureIPF @ats-clinicalprobs.bsky.social @tkulkarni.bsky.social @jskim8223.bsky.social
pmc.ncbi.nlm.nih.gov/articles/pmi...
Really cool: "Myeloid-mesenchymal crosstalk drives ARG1-dependent profibrotic metabolism via ornithine in lung fibrosis" - myeloid cells made ornithine ➡️ proline ➡️ collagen in fibroblast.
Kudos Drs Yadav, Bhattacharya & team
www.jci.org/articles/vie...
@jclinical-invest.bsky.social #CureIPF
Kudos Drs Yadav, Bhattacharya & team
www.jci.org/articles/vie...
@jclinical-invest.bsky.social #CureIPF
August 30, 2025 at 10:44 AM
Really cool: "Myeloid-mesenchymal crosstalk drives ARG1-dependent profibrotic metabolism via ornithine in lung fibrosis" - myeloid cells made ornithine ➡️ proline ➡️ collagen in fibroblast.
Kudos Drs Yadav, Bhattacharya & team
www.jci.org/articles/vie...
@jclinical-invest.bsky.social #CureIPF
Kudos Drs Yadav, Bhattacharya & team
www.jci.org/articles/vie...
@jclinical-invest.bsky.social #CureIPF
We were delighted to hear from
Prof Silke Meiners at our Living Lung talk today.
Her talk on the immunoprotesome related to infection inflammation and lung diseases 🫁 such as #COPD and #IPF
Thank you Silke 🙏
#SciSky
#MedSky
#CureIPF
#HealthResearchMatters
@ilfa-ireland.bsky.social
Prof Silke Meiners at our Living Lung talk today.
Her talk on the immunoprotesome related to infection inflammation and lung diseases 🫁 such as #COPD and #IPF
Thank you Silke 🙏
#SciSky
#MedSky
#CureIPF
#HealthResearchMatters
@ilfa-ireland.bsky.social
January 8, 2025 at 6:25 PM
We were delighted to hear from
Prof Silke Meiners at our Living Lung talk today.
Her talk on the immunoprotesome related to infection inflammation and lung diseases 🫁 such as #COPD and #IPF
Thank you Silke 🙏
#SciSky
#MedSky
#CureIPF
#HealthResearchMatters
@ilfa-ireland.bsky.social
Prof Silke Meiners at our Living Lung talk today.
Her talk on the immunoprotesome related to infection inflammation and lung diseases 🫁 such as #COPD and #IPF
Thank you Silke 🙏
#SciSky
#MedSky
#CureIPF
#HealthResearchMatters
@ilfa-ireland.bsky.social
#ILDSky #CureIPF #CurePF
Nintedanib for SSc-ILD at Scleroderma centres in the US.
Not one 🫁 MD on this paper 👀
Are Rheumatologists treating/managing ILD at your centres?
@jskim8223.bsky.social @ipfdoc.bsky.social @tkulkarni.bsky.social @istamina.bsky.social
Nintedanib for SSc-ILD at Scleroderma centres in the US.
Not one 🫁 MD on this paper 👀
Are Rheumatologists treating/managing ILD at your centres?
@jskim8223.bsky.social @ipfdoc.bsky.social @tkulkarni.bsky.social @istamina.bsky.social
April 13, 2025 at 9:01 PM
#ILDSky #CureIPF #CurePF
Nintedanib for SSc-ILD at Scleroderma centres in the US.
Not one 🫁 MD on this paper 👀
Are Rheumatologists treating/managing ILD at your centres?
@jskim8223.bsky.social @ipfdoc.bsky.social @tkulkarni.bsky.social @istamina.bsky.social
Nintedanib for SSc-ILD at Scleroderma centres in the US.
Not one 🫁 MD on this paper 👀
Are Rheumatologists treating/managing ILD at your centres?
@jskim8223.bsky.social @ipfdoc.bsky.social @tkulkarni.bsky.social @istamina.bsky.social
Is fibroblast proliferation important in pulmonary fibrosis? Finally an answer - great paper by the super team of Christopher Molina,Tatsuya Tsukui, and Dean Sheppard
#זScienceMatters
#CureIPF
www.jci.org/articles/vie...
#זScienceMatters
#CureIPF
www.jci.org/articles/vie...
December 1, 2025 at 6:37 AM
Is fibroblast proliferation important in pulmonary fibrosis? Finally an answer - great paper by the super team of Christopher Molina,Tatsuya Tsukui, and Dean Sheppard
#זScienceMatters
#CureIPF
www.jci.org/articles/vie...
#זScienceMatters
#CureIPF
www.jci.org/articles/vie...
Do statins affect outcome & progression of IPF?
Unsurprisingly, answer is YES & NO.
My suggestion - use statins as statins, antifibrotics as antifibrotics.
And keep developing/testing drugs designed to reverse fibrosis.
#CureIPF
www.tandfonline.com/doi/full/10....
www.nature.com/articles/s41...
Unsurprisingly, answer is YES & NO.
My suggestion - use statins as statins, antifibrotics as antifibrotics.
And keep developing/testing drugs designed to reverse fibrosis.
#CureIPF
www.tandfonline.com/doi/full/10....
www.nature.com/articles/s41...
March 23, 2026 at 1:47 PM
Do statins affect outcome & progression of IPF?
Unsurprisingly, answer is YES & NO.
My suggestion - use statins as statins, antifibrotics as antifibrotics.
And keep developing/testing drugs designed to reverse fibrosis.
#CureIPF
www.tandfonline.com/doi/full/10....
www.nature.com/articles/s41...
Unsurprisingly, answer is YES & NO.
My suggestion - use statins as statins, antifibrotics as antifibrotics.
And keep developing/testing drugs designed to reverse fibrosis.
#CureIPF
www.tandfonline.com/doi/full/10....
www.nature.com/articles/s41...
An excellent 🧵on potential application of Mendelian randomization towards target identification and therapeutic development #cureIPF #REMAP-ILD
Using Mendelian Randomisation to identify causal associations in #IPF a 🧵
December 5, 2024 at 11:37 PM
An excellent 🧵on potential application of Mendelian randomization towards target identification and therapeutic development #cureIPF #REMAP-ILD
Always like visiting @thecrick.bsky.social & particularly when it’s to talk with people about fibrosis in this case Multi-Organ fibrosis associated with @dcaction.bsky.social #Telomere #PreventFibrosis
#CureIPF
#CureIPF
November 11, 2024 at 1:46 PM
Always like visiting @thecrick.bsky.social & particularly when it’s to talk with people about fibrosis in this case Multi-Organ fibrosis associated with @dcaction.bsky.social #Telomere #PreventFibrosis
#CureIPF
#CureIPF
1/n
Using snRNAseq we identify a previously undiscovered population of alveolar epithelial cells in IPF - Alveolar Intermediate (ATi) cells - they share features of ATI, ATII and Aberrant Basaloid cells but also have their own distinct features.
#ATi
#CureIPF
www.biorxiv.org/content/10.1...
Using snRNAseq we identify a previously undiscovered population of alveolar epithelial cells in IPF - Alveolar Intermediate (ATi) cells - they share features of ATI, ATII and Aberrant Basaloid cells but also have their own distinct features.
#ATi
#CureIPF
www.biorxiv.org/content/10.1...
June 15, 2025 at 1:11 PM
1/n
Using snRNAseq we identify a previously undiscovered population of alveolar epithelial cells in IPF - Alveolar Intermediate (ATi) cells - they share features of ATI, ATII and Aberrant Basaloid cells but also have their own distinct features.
#ATi
#CureIPF
www.biorxiv.org/content/10.1...
Using snRNAseq we identify a previously undiscovered population of alveolar epithelial cells in IPF - Alveolar Intermediate (ATi) cells - they share features of ATI, ATII and Aberrant Basaloid cells but also have their own distinct features.
#ATi
#CureIPF
www.biorxiv.org/content/10.1...