Y’all I passed my doctoral defense today, it’s Dr. Curli now!!! 💪🏾😤📜
July 31, 2024 at 10:10 PM
Y’all I passed my doctoral defense today, it’s Dr. Curli now!!! 💪🏾😤📜
August 8, 2025 at 9:40 PM
Bacteria fending off bacterial predators with Curli amyloid proteins!
July 3, 2025 at 5:04 AM
Bacteria fending off bacterial predators with Curli amyloid proteins!
Curli fibers produced by E. coli initiate innate immune responses at mucosal surfaces. Researchers engineered E. coli Nissle 1917 to produce modified curli fibers designed to reduce TLR2 signaling through2 mechanistically distinct strategies. #IAIJournal: asm.social/36I
September 30, 2026 at 11:22 AM
Curli fibers produced by E. coli initiate innate immune responses at mucosal surfaces. Researchers engineered E. coli Nissle 1917 to produce modified curli fibers designed to reduce TLR2 signaling through2 mechanistically distinct strategies. #IAIJournal: asm.social/36I
Nutrient availability influences E. coli biofilm properties and the structure of purified curli amyloid fibers
NPJ Biofilms and Microbiomes from Cecile Bidan
www.nature.com/articles/s41...
NPJ Biofilms and Microbiomes from Cecile Bidan
www.nature.com/articles/s41...
Nutrient availability influences E. coli biofilm properties and the structure of purified curli amyloid fibers - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - Nutrient availability influences E. coli biofilm properties and the structure of purified curli amyloid fibers
www.nature.com
December 6, 2024 at 4:16 PM
Nutrient availability influences E. coli biofilm properties and the structure of purified curli amyloid fibers
NPJ Biofilms and Microbiomes from Cecile Bidan
www.nature.com/articles/s41...
NPJ Biofilms and Microbiomes from Cecile Bidan
www.nature.com/articles/s41...
Curli-cu-cumber...
September 14, 2026 at 10:55 PM
Curli-cu-cumber...
Challenge accepted.
July 22, 2026 at 10:52 PM
Challenge accepted.
July 22, 2026 at 8:25 PM
I wrote a Preview in @cp-cellhostmicrobe.bsky.social !
A new study suggests that #curli may protect prey from bacterial predators like #Bdellovibrio.
Really looking forward to seeing this model confirmed with live-cell imaging and specific reporters!
www.cell.com/cell-host-mi...
A new study suggests that #curli may protect prey from bacterial predators like #Bdellovibrio.
Really looking forward to seeing this model confirmed with live-cell imaging and specific reporters!
www.cell.com/cell-host-mi...
When predators meet the matrix: Natural resistance via amyloid fibers
How do bacteria protect themselves against predators? In a recent issue of Nature,
Ledvina et al. reveal curli fibers as a genetically encoded defense against Bdellovibrio
predation in wild E. coli st...
www.cell.com
September 11, 2025 at 9:18 AM
I wrote a Preview in @cp-cellhostmicrobe.bsky.social !
A new study suggests that #curli may protect prey from bacterial predators like #Bdellovibrio.
Really looking forward to seeing this model confirmed with live-cell imaging and specific reporters!
www.cell.com/cell-host-mi...
A new study suggests that #curli may protect prey from bacterial predators like #Bdellovibrio.
Really looking forward to seeing this model confirmed with live-cell imaging and specific reporters!
www.cell.com/cell-host-mi...
Here is where things got really interesting: transposon mutagenesis of one the resistant strains uncovered that production of the functional amyloid curli was responsible for defense against Bdello! Production of curli was both necessary and sufficient for defense demonstrating a new role curli!
July 2, 2025 at 8:10 PM
Here is where things got really interesting: transposon mutagenesis of one the resistant strains uncovered that production of the functional amyloid curli was responsible for defense against Bdello! Production of curli was both necessary and sufficient for defense demonstrating a new role curli!
We found that resistant strains of E. coli completely coat their outer membrane in curli fibers, effectively acting as a molecular suit-of-armor against invading Bdello. Attached TEM: E coli, green; Bdello, orange; curli, purple.
July 2, 2025 at 8:10 PM
We found that resistant strains of E. coli completely coat their outer membrane in curli fibers, effectively acting as a molecular suit-of-armor against invading Bdello. Attached TEM: E coli, green; Bdello, orange; curli, purple.
How do #bacteriophage life history strategies influence host invasion & inter- #phage competition in #biofilms? This study shows that spatial structure shapes invasion success, favoring temperate phages over lytic ones when diffusion is limited @plosbiology.org 🧪 plos.io/47Aripq
April 1, 2026 at 1:36 PM
How do #bacteriophage life history strategies influence host invasion & inter- #phage competition in #biofilms? This study shows that spatial structure shapes invasion success, favoring temperate phages over lytic ones when diffusion is limited @plosbiology.org 🧪 plos.io/47Aripq
JB Editor's Choice: Ratnikava, Lamprecht & Sourjik explore the complex regulation of curli in Escherichia coli.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
January 5, 2026 at 3:43 PM
JB Editor's Choice: Ratnikava, Lamprecht & Sourjik explore the complex regulation of curli in Escherichia coli.
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
journals.asm.org/doi/10.1128/...
@asm.org #JBacteriology
quero ver problematizarem o cutty do jeito que fizeram ano passado… ah esqueci, a curli xcx não é tão famosa a esse ponto, né? hipocrisia do caralho
Charli XCX feat The 1975 vindo aí? Esse pôster foi visto em Manchester, no Reino Unido.
📸: via allypallyxcx no X
📸: via allypallyxcx no X
October 2, 2024 at 1:06 PM
quero ver problematizarem o cutty do jeito que fizeram ano passado… ah esqueci, a curli xcx não é tão famosa a esse ponto, né? hipocrisia do caralho
Based on our model that curli acts like a suit-of-armor we hypothesized that it should also protect against other extracellular threats. We turned to another predatory bacteria, Myxococcus xanthus, which has a distinct lifecycle from Bdello. Amazingly curli also provides robust defense against Myxo!
July 2, 2025 at 8:10 PM
Based on our model that curli acts like a suit-of-armor we hypothesized that it should also protect against other extracellular threats. We turned to another predatory bacteria, Myxococcus xanthus, which has a distinct lifecycle from Bdello. Amazingly curli also provides robust defense against Myxo!
Very cool 😎
Bacterial anillos (like curli) are a defense mechanism against predatory bacteria
Congratulations on great work @hannahledvina.bsky.social @aaronwhiteley.bsky.social and all coauthors
🧪 #microsky
Bacterial anillos (like curli) are a defense mechanism against predatory bacteria
Congratulations on great work @hannahledvina.bsky.social @aaronwhiteley.bsky.social and all coauthors
🧪 #microsky
Words cannot describe how excited I am to share the findings from the second half of my postdoc in @aaronwhiteley.bsky.social's lab where we discover that bacteria use functional amyloids to defend themselves from predatory bacteria. rdcu.be/euu5Y. See thread for details on this epic adventure 1/.
Functional amyloid proteins confer defence against predatory bacteria
Nature - Escherichia coli uses curli fibres, oligomers of the functional amyloid CsgA, as a barrier to protect against the predatory bacteria Bdellovibrio bacteriovorus and Myxococcus xanthus in a...
rdcu.be
July 2, 2025 at 10:16 PM
Very cool 😎
Bacterial anillos (like curli) are a defense mechanism against predatory bacteria
Congratulations on great work @hannahledvina.bsky.social @aaronwhiteley.bsky.social and all coauthors
🧪 #microsky
Bacterial anillos (like curli) are a defense mechanism against predatory bacteria
Congratulations on great work @hannahledvina.bsky.social @aaronwhiteley.bsky.social and all coauthors
🧪 #microsky
Words cannot describe how excited I am to share the findings from the second half of my postdoc in @aaronwhiteley.bsky.social's lab where we discover that bacteria use functional amyloids to defend themselves from predatory bacteria. rdcu.be/euu5Y. See thread for details on this epic adventure 1/.
Functional amyloid proteins confer defence against predatory bacteria
Nature - Escherichia coli uses curli fibres, oligomers of the functional amyloid CsgA, as a barrier to protect against the predatory bacteria Bdellovibrio bacteriovorus and Myxococcus xanthus in a...
rdcu.be
July 2, 2025 at 8:10 PM
Words cannot describe how excited I am to share the findings from the second half of my postdoc in @aaronwhiteley.bsky.social's lab where we discover that bacteria use functional amyloids to defend themselves from predatory bacteria. rdcu.be/euu5Y. See thread for details on this epic adventure 1/.
How do #bacteriophage life history strategies influence host invasion & inter- #phage competition in #biofilms? This study shows that spatial structure shapes invasion success, favoring temperate phages over lytic ones when diffusion is limited @plosbiology.org 🧪 plos.io/47Aripq
April 2, 2026 at 8:00 AM
How do #bacteriophage life history strategies influence host invasion & inter- #phage competition in #biofilms? This study shows that spatial structure shapes invasion success, favoring temperate phages over lytic ones when diffusion is limited @plosbiology.org 🧪 plos.io/47Aripq
Curli is primarily thought to play a role in biofilm formation as it helps stabilize the extracellular matrix. Curli is composed of the functional amyloid protein CsgA, which, just like the amyloids that cause neurodegeneration, form highly stable fibers.
July 2, 2025 at 8:10 PM
Curli is primarily thought to play a role in biofilm formation as it helps stabilize the extracellular matrix. Curli is composed of the functional amyloid protein CsgA, which, just like the amyloids that cause neurodegeneration, form highly stable fibers.
Dan developed two complementary super-resolution fluorescence microscopy approaches (SMLM and SOFI) to visualize curli fibers (the major component of the E. coli biofilm) on living cells! Check out his preprint:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
June 23, 2025 at 12:29 PM
Dan developed two complementary super-resolution fluorescence microscopy approaches (SMLM and SOFI) to visualize curli fibers (the major component of the E. coli biofilm) on living cells! Check out his preprint:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
How do #bacteriophage life history strategies influence host invasion & inter- #phage competition in #biofilms? This study shows that spatial structure shapes invasion success, favoring temperate phages over lytic ones when diffusion is limited @plosbiology.org 🧪 plos.io/47Aripq
April 1, 2026 at 4:30 PM
How do #bacteriophage life history strategies influence host invasion & inter- #phage competition in #biofilms? This study shows that spatial structure shapes invasion success, favoring temperate phages over lytic ones when diffusion is limited @plosbiology.org 🧪 plos.io/47Aripq
Another one on the possible trade-off between nutrition/protection in microbes: E. coli biofilms under low nutrient conditions are macroscopically thicker and have more curli amyloid fibres. Interesting! (and I wonder what exp conditions are closer to real life there)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Nutrient availability influences E. coli biofilm properties and the structure of purified curli amyloid fibers - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - Nutrient availability influences E. coli biofilm properties and the structure of purified curli amyloid fibers
www.nature.com
December 15, 2024 at 1:03 AM
Another one on the possible trade-off between nutrition/protection in microbes: E. coli biofilms under low nutrient conditions are macroscopically thicker and have more curli amyloid fibres. Interesting! (and I wonder what exp conditions are closer to real life there)
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Examples of diverse curli-like operons can be found throughout bacteria with all sorts of interesting accessory genes. Additionally, we (re)identified the functional amyloids of Pseudomonas which had been previously described to, like curli, play a role in biofilm formation.
July 2, 2025 at 8:10 PM
Examples of diverse curli-like operons can be found throughout bacteria with all sorts of interesting accessory genes. Additionally, we (re)identified the functional amyloids of Pseudomonas which had been previously described to, like curli, play a role in biofilm formation.
Maintenant j’ai des trench et des manteaux de fourrure et toute la collection Curli.
August 23, 2025 at 10:41 AM
Maintenant j’ai des trench et des manteaux de fourrure et toute la collection Curli.