Bdellovibrio attacking another cell just looks like the big bacteria is smoking a doobie
April 2, 2025 at 3:40 AM
Bdellovibrio attacking another cell just looks like the big bacteria is smoking a doobie
🚨New paper out! #MicroSky
Studying obligate predators like Bdellovibrio bacteriovorus is tricky—essential genes for predation are also essential for survival.
We expanded its genetic toolbox:
🧬promoters to fine-tune expression
🧬IPTG-inducible system
🧬CRISPRi for rapid knockdown
bit.ly/46GUn2c
1/4
Studying obligate predators like Bdellovibrio bacteriovorus is tricky—essential genes for predation are also essential for survival.
We expanded its genetic toolbox:
🧬promoters to fine-tune expression
🧬IPTG-inducible system
🧬CRISPRi for rapid knockdown
bit.ly/46GUn2c
1/4
Expanding the genetic toolbox of the obligate predatory bacterium Bdellovibrio bacteriovorus with inducible gene expression and CRISPR interference
Inducible gene expression and CRISPR interference-mediated depletion in the predatory bacterium Bdellovibrio bacteriovorus.
academic.oup.com
September 17, 2025 at 7:27 AM
🚨New paper out! #MicroSky
Studying obligate predators like Bdellovibrio bacteriovorus is tricky—essential genes for predation are also essential for survival.
We expanded its genetic toolbox:
🧬promoters to fine-tune expression
🧬IPTG-inducible system
🧬CRISPRi for rapid knockdown
bit.ly/46GUn2c
1/4
Studying obligate predators like Bdellovibrio bacteriovorus is tricky—essential genes for predation are also essential for survival.
We expanded its genetic toolbox:
🧬promoters to fine-tune expression
🧬IPTG-inducible system
🧬CRISPRi for rapid knockdown
bit.ly/46GUn2c
1/4
@bexlowrypalms.bsky.social up next speaking about her work on bdellovibrio #UoM_EEday
January 12, 2026 at 10:29 AM
@bexlowrypalms.bsky.social up next speaking about her work on bdellovibrio #UoM_EEday
Happy to finally show our story of the connection between nucleoid conformation, transcription & predation in our favorite predator Bdellovibrio bacteriovorus. 🧵 1/n
📝New preprint! #MicroSky
🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy.
🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.
www.biorxiv.org/content/10.1...
🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy.
🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.
www.biorxiv.org/content/10.1...
Dynamics and interplay of gene expression and chromosome organization across a predatory lifecycle
The obligate predatory bacterium Bdellovibrio bacteriovorus alternates between a motile attack phase and a growth phase inside another bacterium, during which it undergoes multiple rounds of DNA repli...
www.biorxiv.org
September 26, 2025 at 9:09 AM
Happy to finally show our story of the connection between nucleoid conformation, transcription & predation in our favorite predator Bdellovibrio bacteriovorus. 🧵 1/n
It's been our great pleasure to host @lalouxlab.bsky.social for a seminar today, and we thoroughly enjoyed learning about Bdellovibrio polarity and polar protein targeting. Such an odd little bacterium!
March 16, 2026 at 9:49 PM
It's been our great pleasure to host @lalouxlab.bsky.social for a seminar today, and we thoroughly enjoyed learning about Bdellovibrio polarity and polar protein targeting. Such an odd little bacterium!
Can E.coli 🦠 escape from predation by ‘living antibiotic’ 💊B.bacteriovorus, a predatory bacterium ?
A first preprint from my lab for people interested in: #MicroSky, #Evolution and new ways to treat #AMR and #Bdellovibrio
www.biorxiv.org/content/10.1...
Some findings in the following thread:
A first preprint from my lab for people interested in: #MicroSky, #Evolution and new ways to treat #AMR and #Bdellovibrio
www.biorxiv.org/content/10.1...
Some findings in the following thread:
Outer membrane changes enable evolutionary escape from bacterial predation
To combat antimicrobial resistant pathogens, natural predatory bacteria, like Bdellovibrio bacteriovorus , represent potential alternatives. B. bacteriovorus could be particularly potent as it kills a...
www.biorxiv.org
November 11, 2024 at 8:06 PM
Can E.coli 🦠 escape from predation by ‘living antibiotic’ 💊B.bacteriovorus, a predatory bacterium ?
A first preprint from my lab for people interested in: #MicroSky, #Evolution and new ways to treat #AMR and #Bdellovibrio
www.biorxiv.org/content/10.1...
Some findings in the following thread:
A first preprint from my lab for people interested in: #MicroSky, #Evolution and new ways to treat #AMR and #Bdellovibrio
www.biorxiv.org/content/10.1...
Some findings in the following thread:
I wrote a Preview in @cp-cellhostmicrobe.bsky.social !
A new study suggests that #curli may protect prey from bacterial predators like #Bdellovibrio.
Really looking forward to seeing this model confirmed with live-cell imaging and specific reporters!
www.cell.com/cell-host-mi...
A new study suggests that #curli may protect prey from bacterial predators like #Bdellovibrio.
Really looking forward to seeing this model confirmed with live-cell imaging and specific reporters!
www.cell.com/cell-host-mi...
When predators meet the matrix: Natural resistance via amyloid fibers
How do bacteria protect themselves against predators? In a recent issue of Nature,
Ledvina et al. reveal curli fibers as a genetically encoded defense against Bdellovibrio
predation in wild E. coli st...
www.cell.com
September 11, 2025 at 9:18 AM
I wrote a Preview in @cp-cellhostmicrobe.bsky.social !
A new study suggests that #curli may protect prey from bacterial predators like #Bdellovibrio.
Really looking forward to seeing this model confirmed with live-cell imaging and specific reporters!
www.cell.com/cell-host-mi...
A new study suggests that #curli may protect prey from bacterial predators like #Bdellovibrio.
Really looking forward to seeing this model confirmed with live-cell imaging and specific reporters!
www.cell.com/cell-host-mi...
Fantastic talk by @bexlowrypalms.bsky.social about Bdellovibrio biocontrol 🧫🍅 #UoM_EEday
January 12, 2026 at 11:56 AM
Fantastic talk by @bexlowrypalms.bsky.social about Bdellovibrio biocontrol 🧫🍅 #UoM_EEday
Years ago, a microbiology student made this crocheted Bdellovibrio and prey cell. I would sure like another!
June 18, 2026 at 3:40 AM
Years ago, a microbiology student made this crocheted Bdellovibrio and prey cell. I would sure like another!
Bdellovibrio spp. cut holes in Gram neg prey & eat them from the inside out.
www.microbiologyresearch.org/content/jour...
www.microbiologyresearch.org/content/jour...
Microbe Profile: Bdellovibrio bacteriovorus: a specialized bacterial predator of bacteria
  Bdellovibrio bacteriovorus   is an environmentally-ubiquitous bacterium that uses unique adaptations to kill other bacteria. The best-characterized strain, HD100, has a multistag...
www.microbiologyresearch.org
January 7, 2025 at 2:21 PM
Bdellovibrio spp. cut holes in Gram neg prey & eat them from the inside out.
www.microbiologyresearch.org/content/jour...
www.microbiologyresearch.org/content/jour...
CRISPRi on #Bdellovibrio to study essential genes 🤗🤩 #MicroSky
🚨New paper out! #MicroSky
Studying obligate predators like Bdellovibrio bacteriovorus is tricky—essential genes for predation are also essential for survival.
We expanded its genetic toolbox:
🧬promoters to fine-tune expression
🧬IPTG-inducible system
🧬CRISPRi for rapid knockdown
bit.ly/46GUn2c
1/4
Studying obligate predators like Bdellovibrio bacteriovorus is tricky—essential genes for predation are also essential for survival.
We expanded its genetic toolbox:
🧬promoters to fine-tune expression
🧬IPTG-inducible system
🧬CRISPRi for rapid knockdown
bit.ly/46GUn2c
1/4
Expanding the genetic toolbox of the obligate predatory bacterium Bdellovibrio bacteriovorus with inducible gene expression and CRISPR interference
Inducible gene expression and CRISPR interference-mediated depletion in the predatory bacterium Bdellovibrio bacteriovorus.
academic.oup.com
September 18, 2025 at 8:54 AM
CRISPRi on #Bdellovibrio to study essential genes 🤗🤩 #MicroSky
You thought all OMPs were trimeric? 🧐 Not in our predator B. bacteriovorus! 🦠
Excited to have contributed to this great collab with the Lovering lab on this intriguing protein. @lalouxlab.bsky.social
👉 Paper here!
www.nature.com/articles/s41...
#BacterialPredation #Bdellovibrio #StructuralBiology
Excited to have contributed to this great collab with the Lovering lab on this intriguing protein. @lalouxlab.bsky.social
👉 Paper here!
www.nature.com/articles/s41...
#BacterialPredation #Bdellovibrio #StructuralBiology
A porin-like protein used by bacterial predators defines a wider lipid-trapping superfamily - Nature Communications
This study reveals that an outer membrane protein from the predator Bdellovibrio bacteriovorus forms a pentameric assembly that traps a lipid monolayer within. This allows the discovery of two superfa...
www.nature.com
July 7, 2025 at 6:58 AM
You thought all OMPs were trimeric? 🧐 Not in our predator B. bacteriovorus! 🦠
Excited to have contributed to this great collab with the Lovering lab on this intriguing protein. @lalouxlab.bsky.social
👉 Paper here!
www.nature.com/articles/s41...
#BacterialPredation #Bdellovibrio #StructuralBiology
Excited to have contributed to this great collab with the Lovering lab on this intriguing protein. @lalouxlab.bsky.social
👉 Paper here!
www.nature.com/articles/s41...
#BacterialPredation #Bdellovibrio #StructuralBiology
Multiple small, curved, predatory bacteria (Bdellovibrio bacteriovorus) lyse the bacterial prey remnants below. How are they doing this & which predator proteins are involved in this process?
See our newly released research article 📑
=> rdcu.be/eL6gu
🦠 #microsky #bacteria #PredatoryBacteria
See our newly released research article 📑
=> rdcu.be/eL6gu
🦠 #microsky #bacteria #PredatoryBacteria
October 23, 2025 at 4:44 PM
Multiple small, curved, predatory bacteria (Bdellovibrio bacteriovorus) lyse the bacterial prey remnants below. How are they doing this & which predator proteins are involved in this process?
See our newly released research article 📑
=> rdcu.be/eL6gu
🦠 #microsky #bacteria #PredatoryBacteria
See our newly released research article 📑
=> rdcu.be/eL6gu
🦠 #microsky #bacteria #PredatoryBacteria
DAY 174
SPECIES 174 - Bdellovibrio bacteriovorus
STAGE: Bacteria
MEDIUM: Arches Paper. Chromatic & QoR Watercolor. Derwent Pencil. Sakura Pen
B. bacteriovorus is a predatory bacterium that hunts and consumes other Gram-negative bacteria.
#sciart #watercolor #bacteria #painting #art #paint
SPECIES 174 - Bdellovibrio bacteriovorus
STAGE: Bacteria
MEDIUM: Arches Paper. Chromatic & QoR Watercolor. Derwent Pencil. Sakura Pen
B. bacteriovorus is a predatory bacterium that hunts and consumes other Gram-negative bacteria.
#sciart #watercolor #bacteria #painting #art #paint
November 26, 2025 at 7:43 AM
In the interest of correcting this disappointing search result…
Bdellovibrio are super cool. They eat other bacteria. They’re everywhere, and they’re very speedy.
(Seriously, they’re everywhere. Former student Luke isolated Bdellovibrio from a custodial closet drain.)
Bdellovibrio are super cool. They eat other bacteria. They’re everywhere, and they’re very speedy.
(Seriously, they’re everywhere. Former student Luke isolated Bdellovibrio from a custodial closet drain.)
September 19, 2023 at 1:50 AM
In the interest of correcting this disappointing search result…
Bdellovibrio are super cool. They eat other bacteria. They’re everywhere, and they’re very speedy.
(Seriously, they’re everywhere. Former student Luke isolated Bdellovibrio from a custodial closet drain.)
Bdellovibrio are super cool. They eat other bacteria. They’re everywhere, and they’re very speedy.
(Seriously, they’re everywhere. Former student Luke isolated Bdellovibrio from a custodial closet drain.)
Modulating gene expression and protein secretion in the bacterial predator Bdellovibrio bacteriovorus https://www.biorxiv.org/content/10.1101/2025.05.17.654431v1
May 18, 2025 at 4:17 AM
Modulating gene expression and protein secretion in the bacterial predator Bdellovibrio bacteriovorus https://www.biorxiv.org/content/10.1101/2025.05.17.654431v1
🧬New paper out! We report the first isolation of viable B. bacteriovorus predators from human gut microbiota. www.frontiersin.org/journals/mic.... Great work of Mario Romero @migueldiezfdz.bsky.social @josete600.bsky.social and @rosacampo.bsky.social
Frontiers | Genome assembly and functional predation analysis of novel Bdellovibrio isolates from human gut microbiota
IntroductionPredatory bacteria of the Bdellovibrio and like organisms (BALOs) have long been postulated as living antimicrobials, yet their occurrence and ec...
www.frontiersin.org
February 2, 2026 at 10:52 AM
🧬New paper out! We report the first isolation of viable B. bacteriovorus predators from human gut microbiota. www.frontiersin.org/journals/mic.... Great work of Mario Romero @migueldiezfdz.bsky.social @josete600.bsky.social and @rosacampo.bsky.social
Friday means a new #MattersMicrobial podcast. This week, Dr. Hannah Ledvina joins the #QualityQuorum to chat about how bacteria can shield themselves against Bdellovibrio attack! Please spread the #GoodMicrobialWord. @univpugetsound @ASMicrobiology @microbe.tv
youtu.be/n31kkw576GE?...
youtu.be/n31kkw576GE?...
November 7, 2025 at 6:03 PM
Friday means a new #MattersMicrobial podcast. This week, Dr. Hannah Ledvina joins the #QualityQuorum to chat about how bacteria can shield themselves against Bdellovibrio attack! Please spread the #GoodMicrobialWord. @univpugetsound @ASMicrobiology @microbe.tv
youtu.be/n31kkw576GE?...
youtu.be/n31kkw576GE?...
Words cannot describe how excited I am to share the findings from the second half of my postdoc in @aaronwhiteley.bsky.social's lab where we discover that bacteria use functional amyloids to defend themselves from predatory bacteria. rdcu.be/euu5Y. See thread for details on this epic adventure 1/.
Functional amyloid proteins confer defence against predatory bacteria
Nature - Escherichia coli uses curli fibres, oligomers of the functional amyloid CsgA, as a barrier to protect against the predatory bacteria Bdellovibrio bacteriovorus and Myxococcus xanthus in a...
rdcu.be
July 2, 2025 at 8:10 PM
Words cannot describe how excited I am to share the findings from the second half of my postdoc in @aaronwhiteley.bsky.social's lab where we discover that bacteria use functional amyloids to defend themselves from predatory bacteria. rdcu.be/euu5Y. See thread for details on this epic adventure 1/.
Bdellovibrio bacteriovorus? No idea about when the behavior evolved.
January 7, 2025 at 1:43 AM
Bdellovibrio bacteriovorus? No idea about when the behavior evolved.
New tools unlock #Bdellovibrio bacteriovorus’s predatory secrets 🦠. By combining inducible gene expression with #CRISPRi-mediated depletion for precise control of essential genes, @lalouxlab.bsky.social uncovered new insights into its unique lifecycle and cell division.
buff.ly/FcDzAY4
buff.ly/FcDzAY4
October 14, 2025 at 9:02 AM
New tools unlock #Bdellovibrio bacteriovorus’s predatory secrets 🦠. By combining inducible gene expression with #CRISPRi-mediated depletion for precise control of essential genes, @lalouxlab.bsky.social uncovered new insights into its unique lifecycle and cell division.
buff.ly/FcDzAY4
buff.ly/FcDzAY4
