#cyclophosphamide
Pharmaceuticals are a bad place to start with 'someone should understand how it works.'

Cytoxan is standard chemo, first approved in 1959. As its label says, nobody really knows its mechanism of action.
October 11, 2026 at 12:24 PM
petite ironie : les moutardes azotées sont dérivées du gaz moutarde utilisé comme gaz de guerre pendant la 1ère guerre mondiale et sont les premières chimiothérapies utilisées dans les années 40… (on en utilise encore aujourd'hui : chlorambucil, cyclophosphamide, melphalan… ifosfamide)
October 11, 2026 at 3:37 PM
Cyclophosphamide Shortage Drives China Price Surge as Europe Warns of Supply Limits Into 2027
#China #Health
Cyclophosphamide Shortage Drives China Price Surge as Europe Warns of Supply Limits Into 2027
A 24 yuan cancer medicine becomes difficult to find Injectable cyclophosphamide, a chemotherapy medicine normally listed at about 24 yuan per vial in China, has been offered online for 600 to 650 yuan during a shortage that has disrupted hospital…
asiadaily.org
October 11, 2026 at 7:00 PM
A @bloodadvances.bsky.socials study shows reduced-intensity conditioning haplo-BMT with posttransplant cyclophosphamide achieved a 96% overall survival rate in young severe aplastic anemia patients, offering a safe and effective cure. 🩸

Read more: https://bit.ly/4i4Li9b

#PedHem
October 9, 2026 at 1:20 PM
Piramal Pharma and NP2 Complete Development Phase of Cyclophosphamide Next Month#USA#Lexington#NP2#Cyclophosphamide#Piramal
Piramal Pharma and NP2 Complete Development Phase of Cyclophosphamide Next Month
Piramal Pharma Solutions and NP2 will finalize the development phase of the generic cancer drug, Cyclophosphamide, in October 2026, enhancing supply security.
third-news.com
October 1, 2026 at 1:14 PM
Piramal Pharma and NP2 to Complete Cyclophosphamide Development Phase Next Month#USA#Lexington#Piramal_Pharma#NP2#Cyclophosphamide
Piramal Pharma and NP2 to Complete Cyclophosphamide Development Phase Next Month
Piramal Pharma Solutions and NP2 are set to complete the cyclophosphamide development phase by next month, aiming to enhance cancer drug availability.
third-news.com
October 1, 2026 at 1:18 PM
Piramal Pharma and NP2 to Finalize Cyclophosphamide Development by Next Month#USA#Lexington#Piramal_Pharma#NP2#Cyclophosphamide
Piramal Pharma and NP2 to Finalize Cyclophosphamide Development by Next Month
Piramal Pharma Solutions partners with NP2 to complete the development phase of cyclophosphamide, addressing critical shortages in cancer treatment.
third-news.com
September 30, 2026 at 2:18 PM
Piramal Pharma Solutions and NP2 Set to Conclude Cyclophosphamide Development Stage Soon#United_States#Lexington#Piramal_Pharma#NP2#Cyclophosphamide
Piramal Pharma Solutions and NP2 Set to Conclude Cyclophosphamide Development Stage Soon
Piramal Pharma Solutions and NP2 aim to finish developing cyclophosphamide, a crucial cancer treatment drug, next month in a bid to ensure a stable supply for patients.
third-news.com
September 30, 2026 at 1:54 PM
Article a #Docusalut: Outcomes of Allogeneic Hematopoietic Cell Transplantation with Post-Transplant Cyclophosphamide Prophylaxis in Myelodysplastic Syndromes: A Multicenter Study Conducted on Behalf of GETH-TC https://hdl.handle.net/20.500.13003/27485
September 30, 2026 at 12:01 PM
Even in strict situations where "consulting teams don't place orders" there is still precedent for consulting teams placing orders. Patient goes for a procedure? Orders placed by consultants. Rheum situation and they are getting cyclophosphamide? We will order (once we/I remember exactly how...).
September 28, 2026 at 10:45 PM
Severity of IEC-Parkinsonism was reduced, although overall incidence rate of delayed neurotoxicities & peak ALC expansion after cilta-cel unchanged w/ prophylactic cyclophosphamide, per observational study shared by Christoph Schaefers, MD #IMS26
September 26, 2026 at 1:22 PM
An observational analysis showed a long-term OS benefit with Orca-T in adult patients undergoing allogeneic transplantation for hematologic malignancies. #hematology #oncology

Learn more ➡️: www.onclive.com/view/orca-t-...
Orca-T Improves Long-Term OS Survival vs Post-Transplant Cyclophosphamide in Hematologic Malignancies | OncLive
An observational analysis showed a long-term OS benefit with Orca-T in adult patients undergoing allogeneic transplantation for hematologic malignancies.
www.onclive.com
September 22, 2026 at 2:50 PM
This study demonstrates that #CHOP deficiency intensifies inflammation, epithelial #apoptosis, and injury in OAB mice by suppressing #ERStress, pointing to CHOP as a therapeutic axis. #medsky

Read more: doi.org/10.1007/s115...

#currentmedicalscience #Urology
September 21, 2026 at 1:49 PM
The authors included RRIDs in their in Autonomic Neuroscience paper! RRIDs improve reproducibility in scientific research. #ReproducibleResearch #RRID #OpenScience
Differential heat shock protein transcript expression in mouse lower urinary tract (LUT) pathways in cyclophosphamide (CYP)-induced cystitis or repeated variate stress (RVS)
Read the full paper: Differential heat shock protein transcript expression in mouse lower urinary tract (LUT) pathways in cyclophosphamide (CYP)-induced cystitis or repeated variate stress (RVS)
doi.org
September 18, 2026 at 7:00 AM
Short-Interval, Low-Dose versus High-Dose Cyclophosphamide for Menstrual Disorders in Systemic Lupus Erythematosus: A Multicenter Real-World Study #NeuroDegeneration 🧪🧠
https://www.researchsquare.com/article/rs-10761736/latest
September 15, 2026 at 10:01 AM
Immunomodulatory Potential of Vietnamese Ganoderma Species: A Comparative Study in a Cyclophosphamide-Induced Immunosuppressed Model

www.rjpharmacognosy.ir/article_2445...
Immunomodulatory Potential of Vietnamese Ganoderma Species: A Comparative Study in a Cyclophosphamide-Induced Immunosuppressed Model
Background and objectives: Ganoderma species are widely used in traditional medicine for their immunomodulatory properties. However, systematic evaluations of indigenous Vietnamese taxa remain limited...
www.rjpharmacognosy.ir
September 13, 2026 at 10:15 AM
Induction and extended consolidation with daratumumab, cyclophosphamide, bortezomib, lenalidomide, and dexamethasone in patients with high-risk multiple #Myeloma (OPTIMUM/MUKnine): 5-year follow-up of a multicentre, externally controlled, phase 2 trial. www.thelancet.com/journals/lan...
Induction and extended consolidation with daratumumab, cyclophosphamide, bortezomib, lenalidomide, and dexamethasone in patients with high-risk multiple myeloma (OPTIMUM/MUKnine): 5-year follow-up of ...
OPTIMUM shows sustained progression-free survival and overall survival improvement with risk-stratified extended therapy, supporting implementation of molecular diagnostics and tailored treatment in p...
www.thelancet.com
September 11, 2026 at 8:44 AM
That’s great news! I (63, F) have high risk MM - t(4:14) and 1q gain. My treatment in the US has been similar, but without the cyclophosphamide. Maintenance is daratumumab, dexamethasone, and bortezomib. At 2-1/2 years in, I’m as healthy as ever (I mean, except for the cancer 🤣).
September 8, 2026 at 12:48 PM
Benralizumab for eosinophilic granulomatosis with polyangiitis and subclinical cardiac involvement: a fertility-preserving case report
Benralizumab for eosinophilic granulomatosis with polyangiitis and subclinical cardiac involvement: a fertility-preserving case report - PubMed
Cardiac involvement, which may remain clinically silent, is a major determinant of prognosis in eosinophilic granulomatosis with polyangiitis (EGPA), and remission induction generally requires glucocorticoids combined with cyclophosphamide or rituximab. In contrast, treatment selection may be challe …
pubmed.ncbi.nlm.nih.gov
September 4, 2026 at 2:05 AM
Open Access UCL Research: Vinorelbine and low-dose cyclophosphamide as maintenance therapy in the treatment of Ewing sarcoma rationale for the international INTER-EWING-1 trial for Ewing sarcoma patients discovery.ucl.ac.uk/id/eprint/10...
Vinorelbine and low-dose cyclophosphamide as maintenance therapy in the treatment of Ewing sarcoma rationale for the international INTER-EWING-1 trial for Ewing sarcoma patients - ...
UCL Discovery is UCL's open access repository, showcasing and providing access to UCL research outputs from all UCL disciplines.
discovery.ucl.ac.uk
September 3, 2026 at 12:21 PM
🔗 #StemCellEvidence link to:

Reduced-Dose Post-Transplant Cyclophosphamide as Graft-Versus-Host Disease Prophylaxis in Matched Donor Allogeneic Stem Cell Transplantation: A #SystematicReview of Efficacy and Toxicity
by Shafqat et al.
www.stemcellevidence.com/alerts/artic...
#MedSky
Reduced-Dose Post-Transplant Cyclophosphamide as Graft-Versus-Host Disease Prophylaxis in Matched Donor Allogeneic Stem Cell Transplantation: A Systematic Review of Efficacy and Toxicity
The standard 100 mg/kg dose of post-transplant cyclophosphamide (PTCy) for graft-versus-host disease (GVHD) prophylaxis after matched allogeneic stem cell transplantation (ASCT) is associated with imp...
www.stemcellevidence.com
September 1, 2026 at 7:41 AM
🆕From the #StemCellEvidence alert:

📑Reduced-Dose Post-Transplant Cyclophosphamide as Graft-Versus-Host Disease Prophylaxis in Matched Donor Allogeneic Stem Cell Transplantation: A #SystematicReview of Efficacy and Toxicity
by Shafqat et al.

🔗Link in the comments
#MedSky
September 1, 2026 at 7:40 AM
The issue that was raised was around licensing, not affordability.

And lots of off patent drugs form the backbone of many cancer treatments. Drugs like 5FU, cisplatin, epirubicin, cyclophosphamide and methotrexate are freely available in most normal developed countries.
August 31, 2026 at 10:21 PM