Current Medical Science
@currentmedscience.bsky.social
Current Medical Science is a peer-reviewed journal publishing original, innovative & influential insightful reviews, comments, & special topic articles across diverse medical disciplines, including biomedicine, public health, and related fields.
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Celebrating growth!
#CurrentMedicalScience (CMS) achieved a 2025 Journal Impact Factor™ of 2.0 & a #CiteScore of 3.3, advancing visibility in global rankings.
Thanks to our authors, reviewers, Editorial Board & readers for their support.
#OpenAccess: link.springer.com/journal/11596
#ImpactFactor
#CurrentMedicalScience (CMS) achieved a 2025 Journal Impact Factor™ of 2.0 & a #CiteScore of 3.3, advancing visibility in global rankings.
Thanks to our authors, reviewers, Editorial Board & readers for their support.
#OpenAccess: link.springer.com/journal/11596
#ImpactFactor
By analyzing #CD8+, CD4+, NKT, and γδ T cells, this study underscores the promise of TCR‑T, #CART, and checkpoint inhibitors in achieving long‑term AML control and advancing future therapeutic strategies. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
To read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
September 26, 2026 at 2:30 PM
By analyzing #CD8+, CD4+, NKT, and γδ T cells, this study underscores the promise of TCR‑T, #CART, and checkpoint inhibitors in achieving long‑term AML control and advancing future therapeutic strategies. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
To read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
Study links decreased Akkermansia with higher inflammatory risk in unstable angina, pointing to the microbiota’s role in disease & the need for mechanistic clarity. @2024_HUST
Read: doi.org/10.1007/s115...
#currentmedicalscience #ClinicalScience #GutMicrobiota
Read: doi.org/10.1007/s115...
#currentmedicalscience #ClinicalScience #GutMicrobiota
September 25, 2026 at 1:02 PM
Study links decreased Akkermansia with higher inflammatory risk in unstable angina, pointing to the microbiota’s role in disease & the need for mechanistic clarity. @2024_HUST
Read: doi.org/10.1007/s115...
#currentmedicalscience #ClinicalScience #GutMicrobiota
Read: doi.org/10.1007/s115...
#currentmedicalscience #ClinicalScience #GutMicrobiota
This review highlights altered tryptophan #Metabolism in #obesity, underscoring its potential as a therapeutic target for metabolic and psychological comorbidities. #medsky
Know more: doi.org/10.1007/s115...
#currentmedicalscience #ClinicalScience
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#currentmedicalscience #ClinicalScience
September 25, 2026 at 7:00 AM
This review highlights altered tryptophan #Metabolism in #obesity, underscoring its potential as a therapeutic target for metabolic and psychological comorbidities. #medsky
Know more: doi.org/10.1007/s115...
#currentmedicalscience #ClinicalScience
Know more: doi.org/10.1007/s115...
#currentmedicalscience #ClinicalScience
Reciprocal activation between S100A9 and TLR2 amplifies hypertrophic signaling in mechanically stretched #cardiomyocytes, exacerbating maladaptive remodeling and likely accelerating HF progression, highlighting therapeutic targets. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience
To read: doi.org/10.1007/s115...
#currentmedicalscience
September 24, 2026 at 1:35 PM
Reciprocal activation between S100A9 and TLR2 amplifies hypertrophic signaling in mechanically stretched #cardiomyocytes, exacerbating maladaptive remodeling and likely accelerating HF progression, highlighting therapeutic targets. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience
To read: doi.org/10.1007/s115...
#currentmedicalscience
The global burden of PAH is rising unevenly, with high SDI regions seeing more cases. The study calls for equitable resources and better diagnostics. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Cardiology #HealthEquity #GlobalHealth
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Cardiology #HealthEquity #GlobalHealth
September 23, 2026 at 1:34 PM
The global burden of PAH is rising unevenly, with high SDI regions seeing more cases. The study calls for equitable resources and better diagnostics. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Cardiology #HealthEquity #GlobalHealth
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Cardiology #HealthEquity #GlobalHealth
Combination therapy shows promise in #schistosomiasis care.
YCHD and PZQ reduce #granulomatous inflammation and #fibrosis by inhibiting apoptosis and ER stress, offering therapeutic promise. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology
YCHD and PZQ reduce #granulomatous inflammation and #fibrosis by inhibiting apoptosis and ER stress, offering therapeutic promise. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology
September 23, 2026 at 2:15 AM
Combination therapy shows promise in #schistosomiasis care.
YCHD and PZQ reduce #granulomatous inflammation and #fibrosis by inhibiting apoptosis and ER stress, offering therapeutic promise. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology
YCHD and PZQ reduce #granulomatous inflammation and #fibrosis by inhibiting apoptosis and ER stress, offering therapeutic promise. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology
The #MUFA content of #Avocado oil varies by cultivar.
This study highlights metabolic promise but calls for standardization of therapeutic applications across cultivars. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #FoodScience #ClinicalNutrition
This study highlights metabolic promise but calls for standardization of therapeutic applications across cultivars. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #FoodScience #ClinicalNutrition
September 22, 2026 at 1:15 PM
The #MUFA content of #Avocado oil varies by cultivar.
This study highlights metabolic promise but calls for standardization of therapeutic applications across cultivars. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #FoodScience #ClinicalNutrition
This study highlights metabolic promise but calls for standardization of therapeutic applications across cultivars. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #FoodScience #ClinicalNutrition
This study demonstrates that #CHOP deficiency intensifies inflammation, epithelial #apoptosis, and injury in OAB mice by suppressing #ERStress, pointing to CHOP as a therapeutic axis. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Urology
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Urology
September 21, 2026 at 1:49 PM
This study demonstrates that #CHOP deficiency intensifies inflammation, epithelial #apoptosis, and injury in OAB mice by suppressing #ERStress, pointing to CHOP as a therapeutic axis. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Urology
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Urology
#WorldAlzheimersDay | September 21, 2026
Research in #AlzheimersDisease expands understanding of early detection and translational #neuroscience.
Current Medical Science publishes peer-reviewed research in #neurodegeneration and clinical innovation.
See recent studies: t.co/5LdKznXcNc
Research in #AlzheimersDisease expands understanding of early detection and translational #neuroscience.
Current Medical Science publishes peer-reviewed research in #neurodegeneration and clinical innovation.
See recent studies: t.co/5LdKznXcNc
September 21, 2026 at 12:45 PM
#WorldAlzheimersDay | September 21, 2026
Research in #AlzheimersDisease expands understanding of early detection and translational #neuroscience.
Current Medical Science publishes peer-reviewed research in #neurodegeneration and clinical innovation.
See recent studies: t.co/5LdKznXcNc
Research in #AlzheimersDisease expands understanding of early detection and translational #neuroscience.
Current Medical Science publishes peer-reviewed research in #neurodegeneration and clinical innovation.
See recent studies: t.co/5LdKznXcNc
This study summarizes the role of #TranscriptionFactors in #ALD pathology—from lipid metabolism to ER stress—and highlights promising targeted therapies for ALD treatment. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology #Epigenetics
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology #Epigenetics
September 20, 2026 at 1:01 PM
This study summarizes the role of #TranscriptionFactors in #ALD pathology—from lipid metabolism to ER stress—and highlights promising targeted therapies for ALD treatment. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology #Epigenetics
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology #Epigenetics
SIC raises mortality; pre‑SIC increases risk.
A #nomogram-based prediction model enables early SIC identification, improving #sepsis management & outcomes. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Epidemiology #IntensiveCare
A #nomogram-based prediction model enables early SIC identification, improving #sepsis management & outcomes. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Epidemiology #IntensiveCare
September 19, 2026 at 1:45 PM
SIC raises mortality; pre‑SIC increases risk.
A #nomogram-based prediction model enables early SIC identification, improving #sepsis management & outcomes. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Epidemiology #IntensiveCare
A #nomogram-based prediction model enables early SIC identification, improving #sepsis management & outcomes. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Epidemiology #IntensiveCare
Can a natural compound protect the #Liver from alcohol induced iron overload?
This study reveals that #quercetin sustains ferritinophagic flux & lysosomal function via #FOXO1 TFEB NCOA4 signaling. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology
This study reveals that #quercetin sustains ferritinophagic flux & lysosomal function via #FOXO1 TFEB NCOA4 signaling. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology
September 18, 2026 at 2:15 PM
Can a natural compound protect the #Liver from alcohol induced iron overload?
This study reveals that #quercetin sustains ferritinophagic flux & lysosomal function via #FOXO1 TFEB NCOA4 signaling. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology
This study reveals that #quercetin sustains ferritinophagic flux & lysosomal function via #FOXO1 TFEB NCOA4 signaling. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Hepatology
SAE drives high morbidity and mortality. This review shows how #lncRNAs modulate #inflammation, metabolism, and immune function — impacting the blood brain barrier and neurons. #medsky
Read: doi.org/10.1007/s115...
#currentmedicalscience #Neurobiology #Sepsis
Read: doi.org/10.1007/s115...
#currentmedicalscience #Neurobiology #Sepsis
September 18, 2026 at 7:00 AM
SAE drives high morbidity and mortality. This review shows how #lncRNAs modulate #inflammation, metabolism, and immune function — impacting the blood brain barrier and neurons. #medsky
Read: doi.org/10.1007/s115...
#currentmedicalscience #Neurobiology #Sepsis
Read: doi.org/10.1007/s115...
#currentmedicalscience #Neurobiology #Sepsis
#Sepsis therapy breakthrough: #electroacupuncture at BL23 enhances antibiotic efficacy by modulating PVN activity and controlling systemic #inflammation, revealing a novel #neuroimmunological pathway for critical care. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
September 17, 2026 at 1:01 PM
#Sepsis therapy breakthrough: #electroacupuncture at BL23 enhances antibiotic efficacy by modulating PVN activity and controlling systemic #inflammation, revealing a novel #neuroimmunological pathway for critical care. #medsky
Read: doi.org/10.1007/s115...
Read: doi.org/10.1007/s115...
#Multiomics analysis links #Ferroptosis risk groups to HCC’s immune microenvironment. #GRINA inhibition induces mitochondrial damage & ferroptosis in HCC cells, offering a novel therapeutic strategy. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
September 16, 2026 at 3:01 PM
#Multiomics analysis links #Ferroptosis risk groups to HCC’s immune microenvironment. #GRINA inhibition induces mitochondrial damage & ferroptosis in HCC cells, offering a novel therapeutic strategy. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
#PMEPA1 impairs Treg‑mediated #immunosuppression by hyperactivating PI3K/AKT, fueling ESC invasiveness in #Endometriosis. Targeting this axis may restore immune balance and curb progression. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Immunology
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Immunology
September 15, 2026 at 2:31 PM
#PMEPA1 impairs Treg‑mediated #immunosuppression by hyperactivating PI3K/AKT, fueling ESC invasiveness in #Endometriosis. Targeting this axis may restore immune balance and curb progression. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Immunology
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Immunology
This review highlights #sialylation as a key regulator of OC progression, metastasis, and drug resistance, pointing toward novel therapeutic strategies. #medsky
Learn more: doi.org/10.1007/s115...
#currentmedicalscience #Oncology #Glycosylation
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#currentmedicalscience #Oncology #Glycosylation
September 14, 2026 at 1:20 PM
This review highlights #sialylation as a key regulator of OC progression, metastasis, and drug resistance, pointing toward novel therapeutic strategies. #medsky
Learn more: doi.org/10.1007/s115...
#currentmedicalscience #Oncology #Glycosylation
Learn more: doi.org/10.1007/s115...
#currentmedicalscience #Oncology #Glycosylation
This review highlights how #optogenetics dissects neural mechanisms using light to precisely activate or inhibit specific neurons, combined with behavioral & #electrophysiological analyses. #medsky
Read: doi.org/10.1007/s115...
#currentmedicalscience #Neuroscience #Neurobiology
Read: doi.org/10.1007/s115...
#currentmedicalscience #Neuroscience #Neurobiology
September 13, 2026 at 2:15 PM
This review highlights how #optogenetics dissects neural mechanisms using light to precisely activate or inhibit specific neurons, combined with behavioral & #electrophysiological analyses. #medsky
Read: doi.org/10.1007/s115...
#currentmedicalscience #Neuroscience #Neurobiology
Read: doi.org/10.1007/s115...
#currentmedicalscience #Neuroscience #Neurobiology
#miR146a plays a central role in #neuroinflammation across NDDs. This review highlights its promise as both a biomarker and therapeutic target, paving the way for precision #Neurology. #medsky
Know more: doi.org/10.1007/s115...
#currentmedicalscience #Neuroscience
Know more: doi.org/10.1007/s115...
#currentmedicalscience #Neuroscience
September 12, 2026 at 12:45 PM
#miR146a plays a central role in #neuroinflammation across NDDs. This review highlights its promise as both a biomarker and therapeutic target, paving the way for precision #Neurology. #medsky
Know more: doi.org/10.1007/s115...
#currentmedicalscience #Neuroscience
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#currentmedicalscience #Neuroscience
Systematic review shows how #AI can transform #TraditionalChineseMedicine practices into structured clinical decision systems, enhancing medical decision-making. #medsky
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#currentmedicalscience #Bioinformatics #MedicalAI
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#currentmedicalscience #Bioinformatics #MedicalAI
September 11, 2026 at 3:01 PM
Systematic review shows how #AI can transform #TraditionalChineseMedicine practices into structured clinical decision systems, enhancing medical decision-making. #medsky
Know more: doi.org/10.1007/s115...
#currentmedicalscience #Bioinformatics #MedicalAI
Know more: doi.org/10.1007/s115...
#currentmedicalscience #Bioinformatics #MedicalAI
AR-positive #TNBC offers a vital target, but single-agent anti-AR therapies hit steep clinical hurdles. This review outlines how combining AR antagonists with other therapeutic strategies overcomes resistance. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
To read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
September 11, 2026 at 7:00 AM
AR-positive #TNBC offers a vital target, but single-agent anti-AR therapies hit steep clinical hurdles. This review outlines how combining AR antagonists with other therapeutic strategies overcomes resistance. #medsky
To read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
To read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
Why is #CD44v6 exciting in AML?
#Decitabine treatment increases CD44v6 expression on DNMT3A-mutant AML cells, improving recognition & targeting by #CARTcells. A promising step toward precision #Immunotherapy. #medsky
Read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
#Decitabine treatment increases CD44v6 expression on DNMT3A-mutant AML cells, improving recognition & targeting by #CARTcells. A promising step toward precision #Immunotherapy. #medsky
Read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
September 10, 2026 at 12:30 PM
Why is #CD44v6 exciting in AML?
#Decitabine treatment increases CD44v6 expression on DNMT3A-mutant AML cells, improving recognition & targeting by #CARTcells. A promising step toward precision #Immunotherapy. #medsky
Read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
#Decitabine treatment increases CD44v6 expression on DNMT3A-mutant AML cells, improving recognition & targeting by #CARTcells. A promising step toward precision #Immunotherapy. #medsky
Read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology
Elevated #S100A8/A9 drives abnormal #proliferation, migration, #adhesion & #Chemoresistance in #DNMT3A mutant AML. Targeting this pathway could be a promising therapeutic strategy. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Oncology #CancerTherapeutics
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Oncology #CancerTherapeutics
September 9, 2026 at 2:45 PM
Elevated #S100A8/A9 drives abnormal #proliferation, migration, #adhesion & #Chemoresistance in #DNMT3A mutant AML. Targeting this pathway could be a promising therapeutic strategy. #medsky
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Oncology #CancerTherapeutics
Read more: doi.org/10.1007/s115...
#currentmedicalscience #Oncology #CancerTherapeutics
A detailed toxicity profile of SG drugs is revealed through #ClinicalTrial data & FRAES/DDInter, uncovering new adverse reactions & drug interactions, advancing #Pharmacovigilance. #medsky
Read: doi.org/10.1007/s115...
#currentmedicalscience #Pharmacology #Toxicology #DrugSafety
Read: doi.org/10.1007/s115...
#currentmedicalscience #Pharmacology #Toxicology #DrugSafety
September 9, 2026 at 3:15 AM
A detailed toxicity profile of SG drugs is revealed through #ClinicalTrial data & FRAES/DDInter, uncovering new adverse reactions & drug interactions, advancing #Pharmacovigilance. #medsky
Read: doi.org/10.1007/s115...
#currentmedicalscience #Pharmacology #Toxicology #DrugSafety
Read: doi.org/10.1007/s115...
#currentmedicalscience #Pharmacology #Toxicology #DrugSafety
#Computational data clarify how SZKJT activates #Phytochemicals to treat OSCC. This study provides mechanistic insights into phytochemical-based #CancerTherapy. #medsky
Read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology #TranslationalOncology #Phytotherapy #Cancer
Read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology #TranslationalOncology #Phytotherapy #Cancer
September 8, 2026 at 1:03 PM
#Computational data clarify how SZKJT activates #Phytochemicals to treat OSCC. This study provides mechanistic insights into phytochemical-based #CancerTherapy. #medsky
Read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology #TranslationalOncology #Phytotherapy #Cancer
Read: doi.org/10.1007/s115...
#currentmedicalscience #Oncology #TranslationalOncology #Phytotherapy #Cancer