"According to the principle of minimum differentiation, America wants two political parties that are virtually indistinguishable, and that’s exactly what we intend to give them."
buff.ly/ozYCDLy
buff.ly/ozYCDLy
Democrats Need to Win Back Voters by Becoming Republicans
“According to the principle of minimum differentiation, America wants two political parties that are virtually indistinguishable, and that’s exactly what we ...
buff.ly
November 2, 2026 at 7:00 PM
"According to the principle of minimum differentiation, America wants two political parties that are virtually indistinguishable, and that’s exactly what we intend to give them."
buff.ly/ozYCDLy
buff.ly/ozYCDLy
i just realized i’ve been mixing up roy cooper and doug jones
sorry old white guys you need to work on your brand differentiation
sorry old white guys you need to work on your brand differentiation
November 4, 2026 at 1:26 AM
i just realized i’ve been mixing up roy cooper and doug jones
sorry old white guys you need to work on your brand differentiation
sorry old white guys you need to work on your brand differentiation
Btw Democrats who support Israel are no different than Haley Stevens — they’re “condemning” her now because their whole operation relies on differentiation from republicans.
To fund Israel is to deny sanctity of life, & to support AI & surveillance & ICE & all the industry that profits from death.
To fund Israel is to deny sanctity of life, & to support AI & surveillance & ICE & all the industry that profits from death.
November 1, 2026 at 8:16 PM
Btw Democrats who support Israel are no different than Haley Stevens — they’re “condemning” her now because their whole operation relies on differentiation from republicans.
To fund Israel is to deny sanctity of life, & to support AI & surveillance & ICE & all the industry that profits from death.
To fund Israel is to deny sanctity of life, & to support AI & surveillance & ICE & all the industry that profits from death.
To read more about this exciting research, please see: pubmed.ncbi.nlm.nih.gov/42893628/
Phasic metabolic remodeling coordinates cardiac myofibroblast differentiation and function - PubMed
Fibroblast differentiation into matrix-producing, contractile myofibroblasts is accompanied by metabolic reprogramming, but whether these changes precede differentiation or arise from the activated ph...
pubmed.ncbi.nlm.nih.gov
November 2, 2026 at 3:00 AM
To read more about this exciting research, please see: pubmed.ncbi.nlm.nih.gov/42893628/
New from me, with a short thread www.nature.com/articles/s41... 1/
The gene ivory:mir-193 controls scale type differentiation in Heliconius butterflies - Nature Communications
Butterfly wing scales are diverse cell types that generate the colours and structures used in communication and adaptation. This study shows that the non-coding RNA ‘ivory’ controls alternative scale-...
www.nature.com
November 2, 2026 at 6:34 PM
New from me, with a short thread www.nature.com/articles/s41... 1/
i would like to share the hyper-local bisexuality / pansexuality differentiation bc i think its a good one
bisexual: attraction to same and other genders; gender influences attraction and/or sexual preferences
pansexual: gender irrelevant to attraction/preferences
bisexual: attraction to same and other genders; gender influences attraction and/or sexual preferences
pansexual: gender irrelevant to attraction/preferences
November 2, 2026 at 7:23 PM
i would like to share the hyper-local bisexuality / pansexuality differentiation bc i think its a good one
bisexual: attraction to same and other genders; gender influences attraction and/or sexual preferences
pansexual: gender irrelevant to attraction/preferences
bisexual: attraction to same and other genders; gender influences attraction and/or sexual preferences
pansexual: gender irrelevant to attraction/preferences
Perhaps the most common refrain I hear from all devs that use AI is, "I only use it for X" and "without it I wouldn't have Y" and it always ends up sounding hollow and seeking permission, attempting nuance and differentiation.
The simple truth is you used it when you weren't forced to.
The simple truth is you used it when you weren't forced to.
November 1, 2026 at 8:47 PM
Perhaps the most common refrain I hear from all devs that use AI is, "I only use it for X" and "without it I wouldn't have Y" and it always ends up sounding hollow and seeking permission, attempting nuance and differentiation.
The simple truth is you used it when you weren't forced to.
The simple truth is you used it when you weren't forced to.
Noah: “hey, where’s Algebra?”
Skylar: (evil smile) “oh we had a differentiation of opinions”
Skylar: (evil smile) “oh we had a differentiation of opinions”
November 3, 2026 at 1:10 PM
Noah: “hey, where’s Algebra?”
Skylar: (evil smile) “oh we had a differentiation of opinions”
Skylar: (evil smile) “oh we had a differentiation of opinions”
well the number thing this is the analytic/synthetic differentiation under logical positivism, in that numbers dont exist in the external world
November 3, 2026 at 5:28 PM
well the number thing this is the analytic/synthetic differentiation under logical positivism, in that numbers dont exist in the external world
Not your thinking, but your essence is differentiation. Therefore you must not strive for what you conceive as distinctiveness, but for your own essence. At bottom, therefore, there is only one striving, namely the striving for one's own essence.~CG Jung, The Red Book
November 2, 2026 at 1:17 AM
Not your thinking, but your essence is differentiation. Therefore you must not strive for what you conceive as distinctiveness, but for your own essence. At bottom, therefore, there is only one striving, namely the striving for one's own essence.~CG Jung, The Red Book
something I think about often is how the first editions of D&D explained the differentiation between "wisdom" and "intelligence" which is "a person can be intelligent enough to know smoking is bad for them, but lacks the wisdom to stop".
November 2, 2026 at 8:11 PM
something I think about often is how the first editions of D&D explained the differentiation between "wisdom" and "intelligence" which is "a person can be intelligent enough to know smoking is bad for them, but lacks the wisdom to stop".
generative differentiation
November 2, 2026 at 11:00 PM
generative differentiation
Studying AI adoption. As of April 2026, 2.9 percent of US consumers paid for AI services. Results point to limited differentiation, close substitutes, and low switching costs, from Mark L. Egan, Dominic Russel, Claire Shi, and Vincent Yao www.nber.org/papers/w35953
October 31, 2026 at 5:02 PM
Studying AI adoption. As of April 2026, 2.9 percent of US consumers paid for AI services. Results point to limited differentiation, close substitutes, and low switching costs, from Mark L. Egan, Dominic Russel, Claire Shi, and Vincent Yao www.nber.org/papers/w35953
GAST/CCK–CCKBR signalling axis controls human definitive endoderm and pancreatic lineage differentiation, informing diabetes cell-therapy protocols. #betacells #diabetes link.springer.com/article/10.1... 🔓
October 30, 2026 at 12:04 PM
GAST/CCK–CCKBR signalling axis controls human definitive endoderm and pancreatic lineage differentiation, informing diabetes cell-therapy protocols. #betacells #diabetes link.springer.com/article/10.1... 🔓
Even for less technical audiences, I am very into the PDS as the unit of explanation and differentiation re: atproto
Centralized platforms own everyone’s identities and data. Atproto’s innovation is letting you own all your data and preferences and move them around. Thus why I use 🎒 and 🐌
Centralized platforms own everyone’s identities and data. Atproto’s innovation is letting you own all your data and preferences and move them around. Thus why I use 🎒 and 🐌
November 3, 2026 at 2:10 PM
Even for less technical audiences, I am very into the PDS as the unit of explanation and differentiation re: atproto
Centralized platforms own everyone’s identities and data. Atproto’s innovation is letting you own all your data and preferences and move them around. Thus why I use 🎒 and 🐌
Centralized platforms own everyone’s identities and data. Atproto’s innovation is letting you own all your data and preferences and move them around. Thus why I use 🎒 and 🐌
On Nov 12, 1pm, join host @hhhcce.bsky.social and @columbiauniversity.bsky.social's Dr. Oliver Hobert at the #FBISeminarSeries. Dr. Hobert will discuss his lab's studies in the simple invertebrate model C. elegans that deciphered genetic mechanisms of sex-specific neuronal differentiation programs.
November 3, 2026 at 1:31 AM
On Nov 12, 1pm, join host @hhhcce.bsky.social and @columbiauniversity.bsky.social's Dr. Oliver Hobert at the #FBISeminarSeries. Dr. Hobert will discuss his lab's studies in the simple invertebrate model C. elegans that deciphered genetic mechanisms of sex-specific neuronal differentiation programs.
Happy to share our latest work, now published in @natcomms.nature.com 🌱
We uncover how GATA transcription factors coordinate the transition from cell proliferation to differentiation in the Arabidopsis root, integrating hormonal signals to regulate root development.
www.nature.com/articles/s41...
We uncover how GATA transcription factors coordinate the transition from cell proliferation to differentiation in the Arabidopsis root, integrating hormonal signals to regulate root development.
www.nature.com/articles/s41...
GATA transcription factors coordinate developmental progression in the arabidopsis root - Nature Communications
Cell type-specific differentiation programs rely upon precise gene regulation. Here, using single-cell analysis, the authors show that phased transcriptional landscapes govern the transition from stem...
www.nature.com
November 3, 2026 at 5:19 PM
Happy to share our latest work, now published in @natcomms.nature.com 🌱
We uncover how GATA transcription factors coordinate the transition from cell proliferation to differentiation in the Arabidopsis root, integrating hormonal signals to regulate root development.
www.nature.com/articles/s41...
We uncover how GATA transcription factors coordinate the transition from cell proliferation to differentiation in the Arabidopsis root, integrating hormonal signals to regulate root development.
www.nature.com/articles/s41...
Explore the hidden world of mitochondria! Trophoblast differentiation in the placenta unveils intricate changes in mitochondrial volume and network complexity—quantified in 3D. PMID:42420306, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-75408-8 #Medsky #Pharmsky #RNA #ASHG 🧪
Electron tomography reveals mitochondrial network and cristae remodelling during cell differentiation in the human placenta | Nature Communications
Mitochondria adapt their structure through fusion and fission, yet how their morphology and cristae architecture change as cells differentiate remains unclear. The human placenta is a valuable model for studying mitochondrial diversity within a single tissue. As epithelial trophoblast cells of the placenta differentiate, their accompanying mitochondria morphologically and functionally transform. We use array tomography to characterise mitochondrial volume and network complexity. Cryo-electron tomography reveals two distinct subpopulations of mitochondria within preparations enriched for progenitor cytotrophoblasts, and a singular, homogeneous population in the differentiated syncytiotrophoblast. We showcase the 3D topology of individual cristae through a standardised metric of “curvedness”. Proteomic analysis of isolated mitochondria identifies reduced levels of proteins involved in mitochondrial dynamics and cristae organisation complexes in the syncytiotrophoblast, accompanied by var
doi.org
November 3, 2026 at 12:00 AM
Explore the hidden world of mitochondria! Trophoblast differentiation in the placenta unveils intricate changes in mitochondrial volume and network complexity—quantified in 3D. PMID:42420306, Nat Commun 2026, @NatureComms https://doi.org/10.1038/s41467-026-75408-8 #Medsky #Pharmsky #RNA #ASHG 🧪
CIRTN works Oct 2026 🎃.
From Drs. Korbutt and Pepper:
“CCKBR signalling controls human definitive endoderm specification and pancreatic lineage differentiation”
PMID: 42900236
link.springer.com/article/10.1...
From Drs. Korbutt and Pepper:
“CCKBR signalling controls human definitive endoderm specification and pancreatic lineage differentiation”
PMID: 42900236
link.springer.com/article/10.1...
CCKBR signalling controls human definitive endoderm specification and pancreatic lineage differentiation - Diabetologia
Aims/hypothesis Paracrine signalling by hormone-producing endocrine cells potentially influences pancreatic development, but this feedback regulation remains poorly understood. Here, we investigated t...
link.springer.com
November 3, 2026 at 6:36 PM
CIRTN works Oct 2026 🎃.
From Drs. Korbutt and Pepper:
“CCKBR signalling controls human definitive endoderm specification and pancreatic lineage differentiation”
PMID: 42900236
link.springer.com/article/10.1...
From Drs. Korbutt and Pepper:
“CCKBR signalling controls human definitive endoderm specification and pancreatic lineage differentiation”
PMID: 42900236
link.springer.com/article/10.1...
Truly. Especially after making differentiation a main focus in life.
October 29, 2026 at 1:49 PM
Truly. Especially after making differentiation a main focus in life.
"Thicc radish" is:
❌My new rapper stage name
✅The result of RsHB8 regulation affecting vascular cambium activity and xylem differentiation during #radish taproot thickening.
Read the paper here⬇️
doi.org/10.1111/jipb...
@wileylifesci.bsky.social
#PlantScience #JIPB #CropScience #thicc
❌My new rapper stage name
✅The result of RsHB8 regulation affecting vascular cambium activity and xylem differentiation during #radish taproot thickening.
Read the paper here⬇️
doi.org/10.1111/jipb...
@wileylifesci.bsky.social
#PlantScience #JIPB #CropScience #thicc
Single‐nucleus RNA sequencing reveals a key regulator RsHB8 affecting vascular cambium activity and xylem differentiation during radish taproot thickening
In xylem differentiation in radish taproots, HOMEOBOX 8 (RsHB8) is proposed to activate transcription of the xyloglucan endotransglucosylase/hydrolase gene RsXTH22 and contribute to cell-wall remodel...
doi.org
October 29, 2026 at 7:32 PM
"Thicc radish" is:
❌My new rapper stage name
✅The result of RsHB8 regulation affecting vascular cambium activity and xylem differentiation during #radish taproot thickening.
Read the paper here⬇️
doi.org/10.1111/jipb...
@wileylifesci.bsky.social
#PlantScience #JIPB #CropScience #thicc
❌My new rapper stage name
✅The result of RsHB8 regulation affecting vascular cambium activity and xylem differentiation during #radish taproot thickening.
Read the paper here⬇️
doi.org/10.1111/jipb...
@wileylifesci.bsky.social
#PlantScience #JIPB #CropScience #thicc
That, or the race for differentiation within the mass mid-market blandness of automotive engineering drives Homer Simpson-levels of design “excellence”.
November 1, 2026 at 6:48 AM
That, or the race for differentiation within the mass mid-market blandness of automotive engineering drives Homer Simpson-levels of design “excellence”.
진짜로 Human support가 상품 Differentiation Point가 되어버렸.....
November 3, 2026 at 10:42 PM
진짜로 Human support가 상품 Differentiation Point가 되어버렸.....
New from Physiological Genomics: Research Article by MN Thompson et al. Bacterial serine protease EspP induces differentiation and expansion of enteroendocrine cells in human colonoids
https://ow.ly/JNHG50ZW49T
https://ow.ly/JNHG50ZW49T
November 3, 2026 at 1:00 PM
New from Physiological Genomics: Research Article by MN Thompson et al. Bacterial serine protease EspP induces differentiation and expansion of enteroendocrine cells in human colonoids
https://ow.ly/JNHG50ZW49T
https://ow.ly/JNHG50ZW49T