A new blood biomarker for Alzheimer's disease accurately tracks Tau protein aggregate build up in the brain www.nature.com/articles/s41... @naturemedicine.bsky.social
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
www.nature.com
March 31, 2025 at 1:58 PM
A new blood biomarker for Alzheimer's disease accurately tracks Tau protein aggregate build up in the brain www.nature.com/articles/s41... @naturemedicine.bsky.social
We now have a blood biomarker that is even more strongly associated with tau PET and cognitive symptoms than even p-tau217! Plasma eMTBR-tau243 will help us to understand whether cognitive impairment is likely to be related to Alzheimer's pathology. #ENDALZ
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
www.nature.com
March 31, 2025 at 2:56 PM
We now have a blood biomarker that is even more strongly associated with tau PET and cognitive symptoms than even p-tau217! Plasma eMTBR-tau243 will help us to understand whether cognitive impairment is likely to be related to Alzheimer's pathology. #ENDALZ
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease www.nature.com/articles/s41...
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
www.nature.com
April 1, 2025 at 7:47 AM
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease www.nature.com/articles/s41...
full paper: www.openread.academy/en/paper/rea...
Breakdown of the paper:
This study aimed to develop a new blood test that can measure a specific type of tau protein called endogenously cleaved microtubule-binding region containing residue 243 (eMTBR-tau243). This tau protein is found in...
Breakdown of the paper:
This study aimed to develop a new blood test that can measure a specific type of tau protein called endogenously cleaved microtubule-binding region containing residue 243 (eMTBR-tau243). This tau protein is found in...
March 31, 2025 at 6:20 PM
full paper: www.openread.academy/en/paper/rea...
Breakdown of the paper:
This study aimed to develop a new blood test that can measure a specific type of tau protein called endogenously cleaved microtubule-binding region containing residue 243 (eMTBR-tau243). This tau protein is found in...
Breakdown of the paper:
This study aimed to develop a new blood test that can measure a specific type of tau protein called endogenously cleaved microtubule-binding region containing residue 243 (eMTBR-tau243). This tau protein is found in...
Open-access 🧪 study here:
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease
www.nature.com/articles/s41...
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease
www.nature.com/articles/s41...
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
www.nature.com
March 31, 2025 at 3:28 PM
Open-access 🧪 study here:
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease
www.nature.com/articles/s41...
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease
www.nature.com/articles/s41...
Discover eMTBR-tau243, a plasma biomarker pinpointing tau tangles in Alzheimer's, promising diagnosis & treatment tracking. PMID:40164726, Nat Med 2025, @NatureMedicine https://doi.org/10.1038/s41591-025-03617-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
doi.org
April 19, 2025 at 6:06 PM
Discover eMTBR-tau243, a plasma biomarker pinpointing tau tangles in Alzheimer's, promising diagnosis & treatment tracking. PMID:40164726, Nat Med 2025, @NatureMedicine https://doi.org/10.1038/s41591-025-03617-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
‼️New publication on a novel plasma biomarker for tau pathology 🧠🧪 in @naturemedicine.bsky.social led by Kanta Horie & @gsalvado.bsky.social:
📖 www.nature.com/articles/s41...
In this study, we investigated plasma eMTBR-tau243, which closely reflects tau tangle pathology in Alzheimer’s disease (AD).
📖 www.nature.com/articles/s41...
In this study, we investigated plasma eMTBR-tau243, which closely reflects tau tangle pathology in Alzheimer’s disease (AD).
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
www.nature.com
March 31, 2025 at 2:44 PM
‼️New publication on a novel plasma biomarker for tau pathology 🧠🧪 in @naturemedicine.bsky.social led by Kanta Horie & @gsalvado.bsky.social:
📖 www.nature.com/articles/s41...
In this study, we investigated plasma eMTBR-tau243, which closely reflects tau tangle pathology in Alzheimer’s disease (AD).
📖 www.nature.com/articles/s41...
In this study, we investigated plasma eMTBR-tau243, which closely reflects tau tangle pathology in Alzheimer’s disease (AD).
Swedish BioFINDER-2 study of 739 people found that a new blood test for eMTBR-tau243 tracks tau tangle buildup in Alzheimer’s better than current plasma biomarkers and rivals brain scans, offering a more accessible tool for diagnosis and trials.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
www.nature.com
March 31, 2025 at 2:49 PM
Swedish BioFINDER-2 study of 739 people found that a new blood test for eMTBR-tau243 tracks tau tangle buildup in Alzheimer’s better than current plasma biomarkers and rivals brain scans, offering a more accessible tool for diagnosis and trials.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A new blood test for #Alzheimers aids in diagnosis also indicates how far disease has progressed. Study in @naturemedicine.bsky.social shows levels of MTBR-tau243 correlates with disease severity. New test could help ID patients likely to benefit from drug treatment. www.nature.com/articles/s41...
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
www.nature.com
March 31, 2025 at 5:34 PM
A new blood test for #Alzheimers aids in diagnosis also indicates how far disease has progressed. Study in @naturemedicine.bsky.social shows levels of MTBR-tau243 correlates with disease severity. New test could help ID patients likely to benefit from drug treatment. www.nature.com/articles/s41...
"plasma eMTBR-tau243 might be a viable alternative to tau-PET for identifying suitable study participants in clinical trials...even more importantly, it might be used as an important study endpoint to cost-effectively determine whether a new therapy affects insoluble tau proteinopathy in the brain."
A new blood biomarker for Alzheimer's disease accurately tracks Tau protein aggregate build up in the brain www.nature.com/articles/s41... @naturemedicine.bsky.social
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
www.nature.com
March 31, 2025 at 2:15 PM
"plasma eMTBR-tau243 might be a viable alternative to tau-PET for identifying suitable study participants in clinical trials...even more importantly, it might be used as an important study endpoint to cost-effectively determine whether a new therapy affects insoluble tau proteinopathy in the brain."
www.nature.com/articles/s41... A blood test to detect Alzheimer’s disease and progression🧐🎉🙌
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
www.nature.com
April 9, 2025 at 4:22 AM
www.nature.com/articles/s41... A blood test to detect Alzheimer’s disease and progression🧐🎉🙌
In our April issue: a prospective cohort study investigating how plasma eMTBR-tau243 might be used together with p-tau217 to support Alzheimer's disease diagnosis and to predict tau tangle accumulation cognitive decline #ADPD2026 www.thelancet.com/journals/lan...
Integration of plasma eMTBR-tau243 and p-tau217 in the diagnosis and stratification of Alzheimer's disease: a prospective cohort study
Plasma %p-tau217 can confirm Aβ-positivity, while eMTBR-tau243 can confirm clinically
symptomatic Alzheimer's disease. Initial testing with %p-tau217 followed by eMTBR-tau243
in %p-tau217-positive pat...
www.thelancet.com
March 20, 2026 at 9:42 AM
In our April issue: a prospective cohort study investigating how plasma eMTBR-tau243 might be used together with p-tau217 to support Alzheimer's disease diagnosis and to predict tau tangle accumulation cognitive decline #ADPD2026 www.thelancet.com/journals/lan...
#Longevity Tip-Finally a blood test that seems to reliably detect Alzheimer’s www.nature.com/articles/s41...
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
www.nature.com
April 1, 2025 at 11:37 PM
#Longevity Tip-Finally a blood test that seems to reliably detect Alzheimer’s www.nature.com/articles/s41...
New publication in JAMA Neurology! 🧠
In this study, led by @gsalvado.bsky.social, we developed and validated a plasma-based biological staging model for Alzheimer’s disease using two blood biomarkers: %p-tau217 and eMTBR-tau243.
jamanetwork.com/journals/jam...
In this study, led by @gsalvado.bsky.social, we developed and validated a plasma-based biological staging model for Alzheimer’s disease using two blood biomarkers: %p-tau217 and eMTBR-tau243.
jamanetwork.com/journals/jam...
Plasma eMTBR-tau243 and %p-tau217 for Biological Staging of Alzheimer Disease
This longitudinal study develops and validates a blood plasma–based biological staging model for Alzheimer disease that closely mirrors an amyloid and tau positron emission tomography–based staging sy...
jamanetwork.com
May 27, 2026 at 8:41 AM
New publication in JAMA Neurology! 🧠
In this study, led by @gsalvado.bsky.social, we developed and validated a plasma-based biological staging model for Alzheimer’s disease using two blood biomarkers: %p-tau217 and eMTBR-tau243.
jamanetwork.com/journals/jam...
In this study, led by @gsalvado.bsky.social, we developed and validated a plasma-based biological staging model for Alzheimer’s disease using two blood biomarkers: %p-tau217 and eMTBR-tau243.
jamanetwork.com/journals/jam...
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
www.nature.com
March 31, 2025 at 10:13 PM
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
#sciencecommunication
#Alzheimer
Great explanation. I read the paper 🔽 and press release, but didn't understand why the tau protein should be an earlier, reliable biomarker than others suggested in the last decade.
#Alzheimer
Great explanation. I read the paper 🔽 and press release, but didn't understand why the tau protein should be an earlier, reliable biomarker than others suggested in the last decade.
May 24, 2025 at 7:53 PM
#sciencecommunication
#Alzheimer
Great explanation. I read the paper 🔽 and press release, but didn't understand why the tau protein should be an earlier, reliable biomarker than others suggested in the last decade.
#Alzheimer
Great explanation. I read the paper 🔽 and press release, but didn't understand why the tau protein should be an earlier, reliable biomarker than others suggested in the last decade.
This is a bit development in Alzheimer’s disease.
Not only is this new Blood Based Biomarker (BBM) 92% accurate but it can differentiate between early and late stage disease.
www.nature.com/articles/s41...
Not only is this new Blood Based Biomarker (BBM) 92% accurate but it can differentiate between early and late stage disease.
www.nature.com/articles/s41...
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
www.nature.com
April 1, 2025 at 4:31 PM
This is a bit development in Alzheimer’s disease.
Not only is this new Blood Based Biomarker (BBM) 92% accurate but it can differentiate between early and late stage disease.
www.nature.com/articles/s41...
Not only is this new Blood Based Biomarker (BBM) 92% accurate but it can differentiate between early and late stage disease.
www.nature.com/articles/s41...
According to researchers Kanta Horie, Gemma Salvadó, Rama Koppisetti, Oskar Hansson, Randall Bateman, et al. newly developed blood test for #Alzheimers not only aids in diagnosis of Alzheimer's but also indicates how far it has progressed. Learn More in Nature Medicine
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease - Nature Medicine
Plasma eMTBR-tau243 is a specific biomarker of tau tangles in Alzheimer’s disease and enables the detecting and tracking of Alzheimer’s clinical impairment.
www.nature.com
April 4, 2025 at 6:52 PM
According to researchers Kanta Horie, Gemma Salvadó, Rama Koppisetti, Oskar Hansson, Randall Bateman, et al. newly developed blood test for #Alzheimers not only aids in diagnosis of Alzheimer's but also indicates how far it has progressed. Learn More in Nature Medicine
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Enhancing Tau Tangle Detection with New Biomarker in Upcoming Xtalks Webinar#Canada#Toronto#Alzheimer's_Disease#Tau_Tangle#eMTBR-Tau
Enhancing Tau Tangle Detection with New Biomarker in Upcoming Xtalks Webinar
Join Xtalks' upcoming webinar to discover how plasma eMTBR-Tau, a new biomarker, can enhance the detection of tau tangles in Alzheimer's disease.
third-news.com
September 16, 2026 at 12:33 PM
Enhancing Tau Tangle Detection with New Biomarker in Upcoming Xtalks Webinar#Canada#Toronto#Alzheimer's_Disease#Tau_Tangle#eMTBR-Tau
📰 #Finance
"Company to host scientific workshop featuring emerging eMTBR-Tau and BD-pTau217 research data for Alzheimer’s disease detection and staging Fremont, CA, July 10, 2026 (GLOBE NEWSWIRE) — Alamar Biosciences, Inc. (Nasdaq: ALMR), a leader in precision proteomics dedicated to…"
"Company to host scientific workshop featuring emerging eMTBR-Tau and BD-pTau217 research data for Alzheimer’s disease detection and staging Fremont, CA, July 10, 2026 (GLOBE NEWSWIRE) — Alamar Biosciences, Inc. (Nasdaq: ALMR), a leader in precision proteomics dedicated to…"
Alamar Biosciences NULISA Data Featured in More Than 140 Scientific Presentations at AAIC 2026, Highlighting Advances in Blood-Based Alzheimer’s Biomarker Profiling
financialpost.com
July 10, 2026 at 11:26 AM
#ALMR Alamar Biosciences NULISA Data Featured in More Than 140 Scientific Presentations at AAIC 2026, Highlighting Advances in Blood-Based Alzheimer’s Biomarker Profiling
https://www.stocktitan.net/news/ALMR/alamar-biosciences-nulisa-data-featured-in-more-than-140-scientific-7nuuidlibglq.html
https://www.stocktitan.net/news/ALMR/alamar-biosciences-nulisa-data-featured-in-more-than-140-scientific-7nuuidlibglq.html
New blood tests for Alzheimer’s take center stage at AAIC 2026
More than 140 AAIC 2026 presentations feature NULISA data, including eMTBR-Tau and BD-pTau217 results on over 220 proteins for earlier Alzheimer’s staging.
www.stocktitan.net
July 10, 2026 at 10:11 AM
#ALMR Alamar Biosciences NULISA Data Featured in More Than 140 Scientific Presentations at AAIC 2026, Highlighting Advances in Blood-Based Alzheimer’s Biomarker Profiling
https://www.stocktitan.net/news/ALMR/alamar-biosciences-nulisa-data-featured-in-more-than-140-scientific-7nuuidlibglq.html
https://www.stocktitan.net/news/ALMR/alamar-biosciences-nulisa-data-featured-in-more-than-140-scientific-7nuuidlibglq.html
#ALMR Alamar Biosciences Launches the First Multiplexed Blood-based Immunoassay for eMTBR-Tau, One of the Most Important Biomarkers in Alzheimer’s Disease Research
https://www.stocktitan.net/news/ALMR/alamar-biosciences-launches-the-first-multiplexed-blood-based-n418pjjy9c7h.html
https://www.stocktitan.net/news/ALMR/alamar-biosciences-launches-the-first-multiplexed-blood-based-n418pjjy9c7h.html
Alamar Biosciences Launches the First Multiplexed Blood-based Immunoassay for eMTBR-Tau, One of the Most Important Biomarkers in Alzheimer’s Disease Research
eMTBR-Tau offers a non-invasive, blood-based measurement of the tau tangle burden, the core pathology associated with disease progression and cognitive decline in Alzheimer’s disease Immunoassay for eMTBR-Tau is available in the NULISAseq™ Neuro 220 panel and as a single-plex assay through the
www.stocktitan.net
July 7, 2026 at 1:12 PM
#ALMR Alamar Biosciences Launches the First Multiplexed Blood-based Immunoassay for eMTBR-Tau, One of the Most Important Biomarkers in Alzheimer’s Disease Research
https://www.stocktitan.net/news/ALMR/alamar-biosciences-launches-the-first-multiplexed-blood-based-n418pjjy9c7h.html
https://www.stocktitan.net/news/ALMR/alamar-biosciences-launches-the-first-multiplexed-blood-based-n418pjjy9c7h.html
📰 #Finance
"eMTBR-Tau offers a non-invasive, blood-based measurement of the tau tangle burden, the core pathology associated with disease progression and cognitive decline in Alzheimer’s disease | Immunoassay for eMTBR-Tau is available in the NULISAseq™ Neuro 220 panel and as a…"
"eMTBR-Tau offers a non-invasive, blood-based measurement of the tau tangle burden, the core pathology associated with disease progression and cognitive decline in Alzheimer’s disease | Immunoassay for eMTBR-Tau is available in the NULISAseq™ Neuro 220 panel and as a…"
Alamar Biosciences Launches the First Multiplexed Blood-based Immunoassay for eMTBR-Tau, One of the Most Important Biomarkers in Alzheimer’s Disease Research
financialpost.com
July 7, 2026 at 2:24 PM