Study shows 4CMenB vaccine might cut N. gonorrhoeae cases. Randomized trial with 1,000 MSM, 2 doses vs. placebo. Promising results! 🚀 PMID:42418797, N Engl J Med 2026, @NEJM https://doi.org/10.1056/NEJMoa2516739 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://doi.org/10.1056/NEJMoa2516739
No description available
doi.org
November 5, 2026 at 3:00 AM
We are delighted to announce that Richard Durbin has been selected by the European Society of Human Genetics to deliver the prestigious 2028 Mendel Lecture, which will take place at the ESHG Conference in Helsinki.
Huge congratulations to Richard!
Huge congratulations to Richard!
November 6, 2026 at 1:56 PM
We are delighted to announce that Richard Durbin has been selected by the European Society of Human Genetics to deliver the prestigious 2028 Mendel Lecture, which will take place at the ESHG Conference in Helsinki.
Huge congratulations to Richard!
Huge congratulations to Richard!
ETBF rewires host metabolism via its virulence factor, Bacteroides fragilis toxin, fueling oxidative growth in the inflamed gut. Key to colitis & cancer risk. PMID:42066751, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00401-0 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00401-0
No description available
www.cell.com
November 6, 2026 at 2:00 AM
CANVAS uses AI to analyze 18 million+ cells in H&E histopathology, revealing tumor microenvironment's influence on progression and therapy resistance. PMID:42302781, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00590-8 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00590-8
No description available
www.cell.com
November 4, 2026 at 2:00 AM
Wang et al. unveil RegVelo, integrating gene regulatory networks with RNA velocity analysis, pinpointing candidate regulators that steer cell fate decisions. PMID:42276033, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600588X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S009286742600588X
No description available
www.cell.com
November 4, 2026 at 12:00 PM
New study analyzes 470 angiosperm genomes, revealing 132 ancient WGD events clustering during environmental upheaval—showcasing polyploidy as a pivotal evolutionary force. PMID:42105759, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00397-1 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00397-1
No description available
www.cell.com
November 3, 2026 at 5:00 AM
AI-driven discovery identifies GPNMB CAR T cells as a promising multi-cancer therapy, enhancing target selection via refined single-cell RNA sequencing analysis. PMID:42349383, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00651-3 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00651-3
No description available
www.cell.com
November 5, 2026 at 7:00 AM
Discovery of Galvanin (TMEM154) reveals its crucial role in electric-field-guided migration of immune/epithelial cells, essential for rapid responses to tissue injury. PMID:42127892, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00461-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00461-7
No description available
www.cell.com
November 4, 2026 at 4:00 AM
Groundbreaking study charts human cellular senescence, revealing 100+ distinct "senotypes" through advanced multi-omics & AI, paving the way for 10+ targeted senotherapies. PMID:42276030, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00587-8 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00587-8
No description available
www.cell.com
November 5, 2026 at 8:00 PM
Study reveals hippocampal neurons in bilinguals share "cross-language" responses for similar concepts across English and Spanish, indicating shared semantic maps. PMID:42341760, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00579-9 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00579-9
No description available
www.cell.com
November 3, 2026 at 5:00 PM
A new study reveals a LLM-based framework that accelerates CAR T target discovery, identifying GPNMB as a promising target across melanoma, leukemia, and colorectal cancer. PMID:42349381, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00652-5 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00652-5
No description available
www.cell.com
November 2, 2026 at 9:00 PM
New D&D-seq method reveals single-cell DNA-protein interactions, capturing transient TF binding insights. Key to understanding gene regulation dynamics! PMID:42242226, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00573-8 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00573-8
No description available
www.cell.com
November 3, 2026 at 11:00 AM
Cysteine's sulfur directs T cell fate: Kelly et al. reveal that its partitioning fuels CD8⁺ T cell growth, function, and anti-tumor immunity. 1 key element, 2 pathways! PMID:42276031, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00570-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00570-2
No description available
www.cell.com
November 6, 2026 at 12:00 AM
MCC recurrence is high at 40%! Study compares ctDNA & MCPyV antibodies in 3 top US centers for better detection. Which is more accurate? #CancerResearch PMID:42418167, JAMA Dermatol 2026 @Stanford https://doi.org/10.1001/jamadermatol.2026.2153 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://doi.org/10.1001/jamadermatol.2026.2153
No description available
doi.org
November 6, 2026 at 11:00 AM
MCC recurrence is high at 40%! Study compares ctDNA & MCPyV antibodies in 3 top US centers for better detection. Which is more accurate? #CancerResearch PMID:42418167, JAMA Dermatol 2026 @Stanford https://doi.org/10.1001/jamadermatol.2026.2153 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
New research shows ~50% of fertilized human eggs arrest in pre-implantation due to error-prone 2nd mitotic divisions. PLK4 inhibition can reduce centriole overduplication! PMID:42276044, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00637-9 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00637-9
No description available
www.cell.com
November 2, 2026 at 10:00 PM
New insights reveal MAP1B, a microtubule-associated protein, shuttles to the nucleus in neural stem cells, linking cytoskeletal dynamics to cell fate & disease. Fascinating! PMID:42276043, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00578-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00578-7
No description available
www.cell.com
November 4, 2026 at 8:00 AM
New SC2r-CoVs clades found in Thai horseshoe bats reveal intriguing virological traits, including human ACE2 receptor binding. This highlights ongoing risk of zoonotic spillover! PMID:42097139, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600454X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S009286742600454X
No description available
www.cell.com
November 4, 2026 at 9:00 PM
New SC2r-CoVs clades found in Thai horseshoe bats reveal intriguing virological traits, including human ACE2 receptor binding. This highlights ongoing risk of zoonotic spillover! PMID:42097139, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600454X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
A new CRISPR knockout mouse library of 84 gene-modified lines enables in vivo functional validation of host factors in influenza A virus research, advancing virology! PMID:42302780, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600591X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S009286742600591X
No description available
www.cell.com
November 5, 2026 at 8:00 AM
New model reveals that mammalian cortical connectomes, with intricate axonal topologies, stem from physical constraints influencing regional connectivity. PMID:42361798, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00648-3 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00648-3
No description available
www.cell.com
November 5, 2026 at 5:00 AM
Exploring SRD: Beyond dopamine! Revealing multiple pathways causing diverse symptoms. Elevate understanding! 🚀🔍 PMID:42418174, JAMA Psychiatry 2026, @JAMAPsych https://doi.org/10.1001/jamapsychiatry.2026.1684 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://doi.org/10.1001/jamapsychiatry.2026.1684
No description available
doi.org
November 3, 2026 at 3:00 AM
New CRISPR screens in primary human CD4+ T cells reveal 40+ pro- and anti-HIV host factors, uncovering diverse antiviral mechanisms. Exciting insights ahead! PMID:42013838, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S009286742600382X #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S009286742600382X
No description available
www.cell.com
November 4, 2026 at 9:00 AM
Unlocking lung cancer prevention: A novel 14-protein plasma signature predicts lung cancer risk 5+ years pre-diagnosis, enhancing trials post-CANTOS! PMID:42242224, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00522-2 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00522-2
No description available
www.cell.com
November 5, 2026 at 10:00 PM
A novel pooled imaging method, VIS-seq, reveals complex, disease-specific impacts of ~3,000 LMNA & PTEN variants on cell morphology and protein dynamics. PMID:42127894, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00466-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00466-6
No description available
www.cell.com
November 5, 2026 at 11:00 AM
LEF1 and niche factors are critical in determining T cell stemness, revealing that TCF1^hi T cells are not solely stem-like in autoimmunity and chronic infection. PMID:42385703, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00709-9 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00709-9
No description available
www.cell.com
November 5, 2026 at 3:00 PM
Frequent prion-based switching of DNA repair proteins boosts mutagenesis in S. cerevisiae, enabling rapid adaptation in diverse environments. Evolution just got a twist! PMID:42263676, Cell 2026, @Cell https://www.cell.com/cell/fulltext/S0092-8674(26)00577-5 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
https://www.cell.com/cell/fulltext/S0092-8674(26)00577-5
No description available
www.cell.com
November 5, 2026 at 1:00 PM