#glomeruli
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collaterly.bsky.social
A small but real increase in fucking kidney function is impressive. would assume recovery of at risk/penumbral glomeruli experiencing ischemic or hyperfiltration injury?
rnflex.bsky.social David W (aka Flex NP) @rnflex.bsky.social · 6d
Finally it reduces hepatic insulin resistance so far that I'm not sure it can go much lower. A 55-60% reduction in fasting insulin.

Also it raised Cystatin-C based GFR by 6-10ml/min.

Legit a medical miracle/fix it all/Mary Sue ass drug as @proptermalone.bsky.social would say.
September 30, 2026 at 1:43 AM
arkanalabs.bsky.social
Interestingly, the perihilar focal segmental glomerulosclerosis identified here was present in numerous glomeruli as well as marked glomerulomegaly.

#renalpath #kidneypath #pathology #renal #pathtwitter
September 29, 2026 at 2:08 PM
biorxivpreprint.bsky.social
Imaging mitral/tufted glomeruli in the mouse olfactory bulb using the genetically encoded voltage indicator ArcLight https://www.biorxiv.org/content/10.64898/2026.09.22.753601v1
September 28, 2026 at 6:15 PM
biorxiv-neursci.bsky.social
Imaging mitral/tufted glomeruli in the mouse olfactory bulb using the genetically encoded voltage indicator ArcLight https://www.biorxiv.org/content/10.64898/2026.09.22.753601v1
September 28, 2026 at 6:15 PM
watanai.bsky.social
＜（ドクター用）「蛋白尿が腎臓を悪くする＞ 糸球体 → 尿細管腔に流れ着いた尿蛋白が、尿細管障害を引き起こす。その結果、尿細管‐糸球体のcrosstalkが生じて糸球体も障害を受ける。そのため、より蛋白尿が出やすくなる悪循環に至る。
www.nature.com/articles/s41...
Crosstalk between glomeruli and tubules - Nature Reviews Nephrology
Glomerular injury and damage to the glomerular filtration barrier can promote the development of tubulointerstitial fibrosis. Here, the authors discuss potential mechanisms underlying this effect, as ...
www.nature.com
September 28, 2026 at 6:44 AM
rainerfriedrichlab.bsky.social
Precise structural and functional organization of the olfactory bulb neuropil early in development, revealed by volume EM, dense reconstruction and 2P calcium imaging in zebrafish. Great work by Ruth and others in collaboration with @michalwj.bsky.social

www.biorxiv.org/content/10.6...
Fine ultrastructural organization of glomerular neuropil in the developing zebrafish olfactory bulb
Across animal phyla, odor information is represented in the first olfactory processing center by combinatorial activation of discrete glomeruli. To examine how this organization of olfactory processin...
www.biorxiv.org
September 26, 2026 at 8:49 PM
runningkidneys.bsky.social
💉 Native kidney biopsy: 99% diagnostic yield in 1,384 patients.

14G vs 16G needles yielded >20 glomeruli more often (81% vs 74%), with similar complication rates (7% vs 8%).

Female sex, higher SBP & lower Hb predicted complications.

🔗 journals.lww.com/kidney360/pd...
September 26, 2026 at 8:38 PM
jzrenalpath.bsky.social
Pt with myelofibrosis, NR proteinuria, progressive CKD. Hypercellular glomeruli + intracapillary megakaryocytes, + mesangial sclerosis, +chronic microangiopathic changes c/w MPN-related glomerulopathy. Also renal extramedullary hematopeosis. IHC is CD61 #renalpath #pathsky #nephsky
September 24, 2026 at 10:39 PM
plosbiology.org
CO2 is an important cue used by #mosquitoes when searching for a human blood meal. @darbly.bsky.social @megyounger.bsky.social &co show that the wiring of #neurons that sense CO2 differs from that in #Drosophila, allowing robust detection of this key host cue @plosbiology.org 🧪 buff.ly/jk3046I
Feedforward connectivity of maxillary palp glomeruli. Top left: Schematic with feedforward OSN-to-PN connections highlighted. Top right: Dendrograms (flattened 2D representations of the 3D dendritic arbor preserving distance information) of uPNs and their incoming feedforward synapses from OSNs. * denotes branch leading to soma, and arrow denotes branch leading to the inner antennocerebral tract (iACT). (top) uPN cable length, glomerular volume, and cable density. Scale bar 100 µm. Bottom left: Coronal view of uPN reconstructions. Scale bar 25 µm. Bottom right: Axograms (flattened 2D representations of the 3D axonal arbor preserving distance information) of representative OSNs with their feedforward synapses to uPNs shown as colored dots. Scale bar 25 µm.
September 14, 2026 at 4:25 PM
mvij.org
Yahweh’s Eden dashboard
fruitflyheaven A stylized fruit fly connectome - real circuit motifs, not the full 130,000-neuron reconstruction - flying a virtual fly around a garden. Retina bins feed lobula columnar cells and antennal glomeruli, which mix in the mushroom body's Kenyon cells; the fly's actual choices come out of the central complex's heading and goal rings. Every fruit eaten potentiates the mushroom-body pathway for whatever it just smelled and saw - so late in a session the fly beelines for fruit it barely noticed at first. Click the garden to drop more fruit. Further down,
September 14, 2026 at 1:52 AM
plosbiology.org
CO2 is an important cue used by #mosquitoes when searching for a human blood meal. @darbly.bsky.social @megyounger.bsky.social &co show that the wiring of #neurons that sense CO2 differs from that in #Drosophila, allowing robust detection of this key host cue @plosbiology.org 🧪 buff.ly/jk3046I
Feedforward connectivity of maxillary palp glomeruli. Top left: Schematic with feedforward OSN-to-PN connections highlighted. Top right: Dendrograms (flattened 2D representations of the 3D dendritic arbor preserving distance information) of uPNs and their incoming feedforward synapses from OSNs. * denotes branch leading to soma, and arrow denotes branch leading to the inner antennocerebral tract (iACT). (top) uPN cable length, glomerular volume, and cable density. Scale bar 100 µm. Bottom left: Coronal view of uPN reconstructions. Scale bar 25 µm. Bottom right: Axograms (flattened 2D representations of the 3D axonal arbor preserving distance information) of representative OSNs with their feedforward synapses to uPNs shown as colored dots. Scale bar 25 µm.
September 11, 2026 at 1:05 PM
plosbiology.org
CO2 is an important cue used by #mosquitoes when searching for a human blood meal. @darbly.bsky.social @megyounger.bsky.social &co show that the wiring of #neurons that sense CO2 differs from that in #Drosophila, allowing robust detection of this key host cue @plosbiology.org 🧪 plos.io/4cFCPpV
Feedforward connectivity of maxillary palp glomeruli. Top left: Schematic with feedforward OSN-to-PN connections highlighted. Top right: Dendrograms (flattened 2D representations of the 3D dendritic arbor preserving distance information) of uPNs and their incoming feedforward synapses from OSNs. * denotes branch leading to soma, and arrow denotes branch leading to the inner antennocerebral tract (iACT). (top) uPN cable length, glomerular volume, and cable density. Scale bar 100 µm. Bottom left: Coronal view of uPN reconstructions. Scale bar 25 µm. Bottom right: Axograms (flattened 2D representations of the 3D axonal arbor preserving distance information) of representative OSNs with their feedforward synapses to uPNs shown as colored dots. Scale bar 25 µm.
September 11, 2026 at 8:50 AM
mosquitopapers.bsky.social
Recurrent synapses between CO2-sensitive olfactory sensory neurons enable robust CO2 detection in Aedes aegypti mosquitoes
The mosquito Aedes aegypti's human host-seeking behavior depends on the integration of multiple sensory cues. One of these cues, carbon dioxide (CO2), gates odorant and heat pathways and activates host-seeking behavior. The neuronal circuits underlying processing of CO2 information remain unclear. We used automated serial-section transmission electron microscopy (EM) to image and reconstruct the circuitry of the glomeruli that are innervated by the Ae. aegypti maxillary palp, including the...
dlvr.it
September 10, 2026 at 10:22 PM
vasculitides.bsky.social
Anti-glomerular basement membrane disease: A contemporary case series from a large university hospital center
Anti-glomerular basement membrane disease: A contemporary case series from a large university hospital center - PubMed
Anti-GBM disease in this Portuguese cohort presented predominantly with severe acute kidney injury requiring RRT and was associated with poor renal recovery despite guideline-directed therapy. Histologic preservation of normal glomeruli and baseline kidney function were strongly associated with rena …
pubmed.ncbi.nlm.nih.gov
August 26, 2026 at 9:02 PM
kidneyint.bsky.social
Nephrology Image
Disappearing glomeruli: loss of linear IgG in anti-GBM nephritis

#MedSky #NephSky
August 11, 2026 at 6:42 PM
kidney.org
IgA nephropathy (IgAN) is one of the most common rare immune-related diseases that damages the kidneys' tiny filters, called glomeruli. For many years, treatment options were limited. Today, that is changing. www.kidney.org/news-stories...
A New Era for IgA Nephropathy: Six New Treatments Bring New Hope
IgA nephropathy (IgAN) is one of the most common rare immune-related diseases that damages the kidneys' tiny filters, called glomeruli. For many years, treatment options were limited. Today, that is…
www.kidney.org
August 6, 2026 at 6:00 PM
jphysiol.bsky.social
Lee Min Leong and colleagues provide evidence that #interglomerular inhibition generates non-monotonic concentration-response relationships in mitral/tufted glomeruli in the mouse #olfactory bulb 🧠 💉

Read the #research👇️
physoc.onlinelibrary.wiley.com/doi/10.1113/...
August 4, 2026 at 11:06 AM
acr-journals.bsky.social
Whole exome sequencing study of 17 patients with ACP5 deficiency from Egypt and China characterized the genetic landscape and clinical spectrum of spondyloenchondrodysplasia with immune dysregulation

Arthritis & Rheumatology
doi.org/10.1002/art....
Clinical characteristics and laboratory tests. The landscape of clinical manifestations in all patients from the previous studies (A) and this study (B). (C) Bar chart shows the proportion of patients by country. Pie chart shows the distribution of patients by region. (D) Bar plot shows effective drugs, ranked by the number of users. (E) Radiological images, immunofluorescence staining of glomeruli, and pathological manifestations of P1. (F) Stacked bar plots show the distribution of laboratory parameters of patients at disease flare in this study.
July 21, 2026 at 9:20 PM
kidneyint.bsky.social
Nephrology Image
Disappearing glomeruli: loss of linear IgG in anti-GBM nephritis

doi.org/10.1016/j.kint.2025.12.041

#NephSky #MedSky
July 20, 2026 at 12:39 PM
olgachaim.bsky.social
Nice adhesion resembles glomeruli cortex assembly. 'Vasa recta' or classic renal structures development can be prospectable by ML. Remodeling of basement membrane by ECM ratios as gradients.
mag2art.bsky.social Dylan Burnette @mag2art.bsky.social · Jul 16
A neuronal growth cone photographed through a microscope. Microtubules and actin filaments are shown. Technique: DIC and widefield fluorescence microscopy. #CellBiology
July 16, 2026 at 6:10 PM
apsphysiology.bsky.social
Could a heart failure drug help protect the kidneys, too?

New research in AJP-Cell suggests empagliflozin may help calm kidney “stress signals,” easing inflammation & helping kidneys work better in heart failure:
https://ow.ly/1t7150ZljrS APS Publications #ArticlesInPress #APSselect 🧪
📷: iStock
Microscopic view of kidney tissue showing two glomeruli stained in vibrant purple hues under high magnification.
July 13, 2026 at 7:00 PM
sciences.skyfleet.blue
Glomage: A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models (Adv. Sci. 39/2026)
Glomage: A Multimodal Platform for High‐Content Morphological and RNA Profiling of Glomeruli in Zebrafish and Mouse Models (Adv. Sci. 39/2026)
Glomage - A Platform for 3D Analyses of Kidney Glomeruli This cover image depicts a depth-color-coded projection of the filtration barrier in an isolated kidney glomerulus of a zebrafish larva. The glomerulus is a highly specialized compartment enabling selective blood filtration through a precisely organized cellular architecture. At its core, the transmembrane protein nephrin forms the slit diaphragm between interdigitating podocyte foot processes, maintaining filtration barrier integrity. In their Research Article (DOI: 10.1002/advs.202523662 ), Maximilian Schindler, Nicole Endlich, and colleagues present Glomage as a powerful multimodal imaging platform for structural and molecular profiling of glomeruli in zebrafish and mouse models. Glomage is an innovative and scalable cross-species approach that opens new dimensions in glomerular research.
advanced.onlinelibrary.wiley.com
July 13, 2026 at 10:29 AM
olegchagin.bsky.social
Kidney cortex, showing numerous glomeruli with their afferent and efferent arterioles and the peritubular capillary complexes.

SEM X75. **On Page Credit Required**

COPYRIGHT:Dr. Richard Kessel & Dr. Randy Kardon/Tissues & Organs/Visuals Unlimited, Inc.
July 12, 2026 at 7:40 AM
scollr.com
A cross-section of the olfactory bulb glows with clusters of glomeruli, the brain's first stop for sorting smell signals. A 2026 eNeuro study tracked the cells that do that sorting with two-photon imaging and found they rewire depending on how an odor is experienced.
Fluorescence-style science image of an olfactory bulb cross-section with five glowing amber and cyan glomeruli on a black background. Yellow text overlay reads: same circuit, different outcome.
July 6, 2026 at 1:28 PM
kidneystories.bsky.social
www.kidneyfund.org/all-about-ki...
Focal segmental glomerulosclerosis (FSGS): symptoms, causes and treatment
Focal segmental glomerulosclerosis (FSGS) is a type of rare kidney disease that causes scarring in parts of the kidney filters, known as glomeruli.
www.kidneyfund.org
June 27, 2026 at 2:11 PM