I know a lot of you haters are pro-histamine. But we have to agree the noble anti-histamine is one of the top 20 human innovations ever. One pill and I'm 80% less snotty.
October 11, 2026 at 11:12 AM
I know a lot of you haters are pro-histamine. But we have to agree the noble anti-histamine is one of the top 20 human innovations ever. One pill and I'm 80% less snotty.
It depends on whether you're more susceptible to histamine liberators or to dietary histamine. (And "high in dietary histamine" is divided into "high in histamine on its own" vs "starts converting histidine into histamine more rapidly when cooked".)
December 21, 2025 at 3:48 PM
It depends on whether you're more susceptible to histamine liberators or to dietary histamine. (And "high in dietary histamine" is divided into "high in histamine on its own" vs "starts converting histidine into histamine more rapidly when cooked".)
Histamine is found in all foods but there are ways to lower the intake to avoid side effects like migraines.
This “Low Histamine Pasta & Cream Sauce” doesn’t contain offenders like cheese, and it’s completely vegan.
https://www.funlivelove.com/low-histamine/low-histamine-pasta-cream-sauce
This “Low Histamine Pasta & Cream Sauce” doesn’t contain offenders like cheese, and it’s completely vegan.
https://www.funlivelove.com/low-histamine/low-histamine-pasta-cream-sauce
April 28, 2023 at 6:51 PM
Histamine is found in all foods but there are ways to lower the intake to avoid side effects like migraines.
This “Low Histamine Pasta & Cream Sauce” doesn’t contain offenders like cheese, and it’s completely vegan.
https://www.funlivelove.com/low-histamine/low-histamine-pasta-cream-sauce
This “Low Histamine Pasta & Cream Sauce” doesn’t contain offenders like cheese, and it’s completely vegan.
https://www.funlivelove.com/low-histamine/low-histamine-pasta-cream-sauce
(Our local sushi place does a great selection of raw vegetarian rolls! They are still higher histamine because of the nori (and soy sauce), but I can eat them on a good day and saving them doesn't change the histamine content!)
May 13, 2025 at 2:24 AM
(Our local sushi place does a great selection of raw vegetarian rolls! They are still higher histamine because of the nori (and soy sauce), but I can eat them on a good day and saving them doesn't change the histamine content!)
MCAS and Histamine: Diet isn’t the Only Answer
Often people think of MCAS as only impacting histamine. They adopt a restrictive low histamine diet - but don’t improve.
This article explains why that is and explores other lifestyle modifications and tips to reduce flare ups:
/9
Often people think of MCAS as only impacting histamine. They adopt a restrictive low histamine diet - but don’t improve.
This article explains why that is and explores other lifestyle modifications and tips to reduce flare ups:
/9
MCAS and Histamine - Diet isn't the ONLY Answer
Mast Cell Activation Syndrome is a beast of a condition that can impact every part of your life. The good news is there are many things you can do on your own to improve symptoms and reduce flares.
www.disabledginger.com
December 7, 2024 at 3:29 AM
MCAS and Histamine: Diet isn’t the Only Answer
Often people think of MCAS as only impacting histamine. They adopt a restrictive low histamine diet - but don’t improve.
This article explains why that is and explores other lifestyle modifications and tips to reduce flare ups:
/9
Often people think of MCAS as only impacting histamine. They adopt a restrictive low histamine diet - but don’t improve.
This article explains why that is and explores other lifestyle modifications and tips to reduce flare ups:
/9
spending all my histamine budget for the day on cheese, because cheese is perfect and can never hurt me and any insinuation it is high histamine is a lie
August 29, 2024 at 3:46 PM
spending all my histamine budget for the day on cheese, because cheese is perfect and can never hurt me and any insinuation it is high histamine is a lie
Actually, not exactly! I recognize everything you list as commonly accepted to be a histamine liberator even if not high histamine itself. So it's not the histamine content of the food itself, it's that it unlocks the stored histamine your cells haven't disposed of yet and dumps it.
December 21, 2025 at 6:00 PM
Actually, not exactly! I recognize everything you list as commonly accepted to be a histamine liberator even if not high histamine itself. So it's not the histamine content of the food itself, it's that it unlocks the stored histamine your cells haven't disposed of yet and dumps it.
TIL estrogen functions as histamine agonist while progesterone functions as an antihistamine
February 3, 2026 at 11:31 PM
TIL estrogen functions as histamine agonist while progesterone functions as an antihistamine
Fucking histamine, man. It's always fucking histamine.
April 30, 2025 at 8:00 PM
Fucking histamine, man. It's always fucking histamine.
I suddenly really want a burrito even though they are histamine bombs goddammit
March 29, 2025 at 11:35 AM
I suddenly really want a burrito even though they are histamine bombs goddammit
- histamine blocker for acid reflux
- histamine blocker for allergies
- histamine blocker for sleep disorders
idk who this histamine person is but theyre toxic af for being on so many block lists and im tired of their shit
- histamine blocker for allergies
- histamine blocker for sleep disorders
idk who this histamine person is but theyre toxic af for being on so many block lists and im tired of their shit
August 10, 2025 at 10:33 PM
- histamine blocker for acid reflux
- histamine blocker for allergies
- histamine blocker for sleep disorders
idk who this histamine person is but theyre toxic af for being on so many block lists and im tired of their shit
- histamine blocker for allergies
- histamine blocker for sleep disorders
idk who this histamine person is but theyre toxic af for being on so many block lists and im tired of their shit
(I thought I had room in the histamine budget and I did not: one woman's story)
March 18, 2025 at 6:30 AM
(I thought I had room in the histamine budget and I did not: one woman's story)
Some people are way more sensitive to histamine liberators, because they have a relatively high dietary histamine tolerance budget before they react, so they have more histamine stored in the bucket and when it gets kicked over, it's worse.
December 21, 2025 at 6:00 PM
Some people are way more sensitive to histamine liberators, because they have a relatively high dietary histamine tolerance budget before they react, so they have more histamine stored in the bucket and when it gets kicked over, it's worse.
(I also react significantly less to histamine liberators than high objective histamine content, because most of my supportive medication is "lower reactivity to all histamine exposure" rather than "increase size of histamine bucket to increase reactivity threshold".)
December 21, 2025 at 6:08 PM
(I also react significantly less to histamine liberators than high objective histamine content, because most of my supportive medication is "lower reactivity to all histamine exposure" rather than "increase size of histamine bucket to increase reactivity threshold".)
Fuck histamine, all my homies hate histamine
April 20, 2024 at 4:06 AM
Fuck histamine, all my homies hate histamine
A lot of people who are way more sensitive to histamine liberators than the pure objective histamine content of food respond really well to taking DAO (diamine oxidase, the enzyme that breaks down histamine) supplements to speed up the plumbing on their waste management system.
December 21, 2025 at 6:00 PM
A lot of people who are way more sensitive to histamine liberators than the pure objective histamine content of food respond really well to taking DAO (diamine oxidase, the enzyme that breaks down histamine) supplements to speed up the plumbing on their waste management system.
1. The underlying science behind the COVID/antihistamine link
There are two major connections between the SARS-CoV-2 virus and histamine. The first is that the virus uses histamine receptors as a method of cell entry/replication: journals.asm.org/doi/10.1128/...
There are two major connections between the SARS-CoV-2 virus and histamine. The first is that the virus uses histamine receptors as a method of cell entry/replication: journals.asm.org/doi/10.1128/...
The histamine receptor H1 acts as an alternative receptor for
SARS-CoV-2 | mBio
In addition to human angiotensin-converting enzyme 2, severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) can utilize alternative cofactors to facilitate viral entry.
In this study, we discov...
journals.asm.org
September 21, 2025 at 9:10 PM
1. The underlying science behind the COVID/antihistamine link
There are two major connections between the SARS-CoV-2 virus and histamine. The first is that the virus uses histamine receptors as a method of cell entry/replication: journals.asm.org/doi/10.1128/...
There are two major connections between the SARS-CoV-2 virus and histamine. The first is that the virus uses histamine receptors as a method of cell entry/replication: journals.asm.org/doi/10.1128/...
It's histamine! Mast cell activation syndrome (MCAS). My exasperated and profane explainer: synecdochic.dreamwidth.org/793547.html Histamine buildup in cooked food is partially bacterial byproducts and partially histidine converting to histamine upon cooking.
Captcha Check
synecdochic.dreamwidth.org
January 5, 2025 at 6:32 AM
It's histamine! Mast cell activation syndrome (MCAS). My exasperated and profane explainer: synecdochic.dreamwidth.org/793547.html Histamine buildup in cooked food is partially bacterial byproducts and partially histidine converting to histamine upon cooking.
It is an antihistamine, it's just a h2 histamine antagonist instead of a h1 histamine antagonist. h1 histamine receptors = sneezing/runny nose, h2 histamine receptors = gastric acid secretion, smooth muscle spasms, vasoconstriction. You need both to chill out the mast cell reaction--
December 22, 2023 at 3:07 AM
It is an antihistamine, it's just a h2 histamine antagonist instead of a h1 histamine antagonist. h1 histamine receptors = sneezing/runny nose, h2 histamine receptors = gastric acid secretion, smooth muscle spasms, vasoconstriction. You need both to chill out the mast cell reaction--
Returning to the histamine bucket analogy: instead of reducing the size of the bucket or adding to the contents of the bucket and increasing the risk of a histamine spill that way, histamine liberators just kick over the bucket to spill it no matter what size it is or how full it is.
December 21, 2025 at 6:00 PM
Returning to the histamine bucket analogy: instead of reducing the size of the bucket or adding to the contents of the bucket and increasing the risk of a histamine spill that way, histamine liberators just kick over the bucket to spill it no matter what size it is or how full it is.
They also found that histamine 2 and 3 receptors don't increase COVID expression, and histamine 4 receptor only weakly increases COVID expression. It's mainly histamine 1, which we have tons of drugs for!!
Antihistamines bind to H1 which then prevent COVID from binding to them!
4/9
Antihistamines bind to H1 which then prevent COVID from binding to them!
4/9
September 7, 2025 at 9:12 PM
They also found that histamine 2 and 3 receptors don't increase COVID expression, and histamine 4 receptor only weakly increases COVID expression. It's mainly histamine 1, which we have tons of drugs for!!
Antihistamines bind to H1 which then prevent COVID from binding to them!
4/9
Antihistamines bind to H1 which then prevent COVID from binding to them!
4/9
Histamine Maxwell.....a "victim"?.....
Saw that comin
Saw that comin
As they try to whitewash the reputation of Trump’s hail mary Ghislaine Maxwell…
July 25, 2025 at 3:03 AM
Histamine Maxwell.....a "victim"?.....
Saw that comin
Saw that comin
Histamine release……maybe lol
October 9, 2026 at 2:06 AM
Histamine release……maybe lol
The updated COVID/histamine link thread because people keep tagging me in to explain it and I keep intending to update the post from 2023 (synecdochic.dreamwidth.org/805203.html) and just not having the capacity because of my own health shit so here is a thread I can pin
Captcha Check
synecdochic.dreamwidth.org
September 21, 2025 at 9:10 PM
The updated COVID/histamine link thread because people keep tagging me in to explain it and I keep intending to update the post from 2023 (synecdochic.dreamwidth.org/805203.html) and just not having the capacity because of my own health shit so here is a thread I can pin