#hostpathogen
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abenaakyaw.bsky.social
Does evolutionary history influence how hosts adapt to new infection routes? We sought to answer this question as a side quest during my PhD and yielded this wonderful story that we are very proud to share in preprint now! 🪰🧬 #HostPathogen, #ExperimentalEvolution, #Drosophila, #Immunity, #Infection
biorxivpreprint.bsky.social bioRxivpreprint @biorxivpreprint.bsky.social · 8d
Historical contingency is revealed by trade-offs upon sequential adaptation to different infection routes https://www.biorxiv.org/content/10.64898/2026.11.05.764508v1
November 7, 2026 at 4:09 PM
mhd-newcastle.bsky.social
🧬 Enigmatic bacterial sphingolipids: probing their regulation and function in host–bacterial interactions

👤 Project supervised by @ruamicro.bsky.social
⏰ Deadline: 24 Nov, 5pm

#PhD #Microbiology #HostPathogen
www.findaphd.com/phds/project...
UKRI BBSRC NEEDL DLA:Enigmatic bacterial sphingolipids: probing their regulation and function in host-bacterial interactions at Newcastle University on FindAPhD.com
PhD Project - UKRI BBSRC NEEDL DLA:Enigmatic bacterial sphingolipids: probing their regulation and function in host-bacterial interactions at Newcastle University, listed on FindAPhD.com
www.findaphd.com
October 30, 2026 at 8:45 PM
plosbiology.org
Mounting an #immune response is energetically costly, and so host defenses are often influenced by internal metabolic states. This study identifies a gut-brain signaling mechanism in C. elegans, shaping pathogen avoidance and molecular immune responses.
🧪 #AcademicSky #hostPathogen
plos.io/3T9f6bi
Conceptual diagram for how NHR-68 integrates lipid metabolism with behavioral and molecular immunity. NHR-68 acts in the intestine to regulate linoleic acid homeostasis through control of fat-3 expression. Changes in intestinal lipid metabolism influence an AWC-dependent pathogen-avoidance circuit through currently unidentified intestine-to-neuron signaling mechanisms, enhancing survival during P. aeruginosa infection. In parallel, NHR-68 suppresses PMK-1/p38 MAPK and DAF-16/FOXO immune pathways, coordinating behavioral and molecular defenses to optimize host protection. Created in BioRender. Sang, Y. (2026).
October 2, 2026 at 4:10 PM
karthiks-lab.bsky.social
Our new study in #JournalofExtracellularVesicles @isev.org shows that host microvesicles carrying pneumolysin remain membrane-active and damage recipient cells beyond canonical pore formation.
Read on the mechanism:
doi.org/10.1002/jev2...
@isev.org
#ExtracellularVesicles #Pneumolysin #HostPathogen
October 1, 2026 at 10:43 AM
plosbiology.org
Mounting an #immune response is energetically costly, and so host defenses are often influenced by internal metabolic states. This study identifies a gut-brain signaling mechanism in C. elegans, shaping pathogen avoidance and molecular immune responses.
🧪 #AcademicSky #hostPathogen
plos.io/3T9f6bi
Conceptual diagram for how NHR-68 integrates lipid metabolism with behavioral and molecular immunity. NHR-68 acts in the intestine to regulate linoleic acid homeostasis through control of fat-3 expression. Changes in intestinal lipid metabolism influence an AWC-dependent pathogen-avoidance circuit through currently unidentified intestine-to-neuron signaling mechanisms, enhancing survival during P. aeruginosa infection. In parallel, NHR-68 suppresses PMK-1/p38 MAPK and DAF-16/FOXO immune pathways, coordinating behavioral and molecular defenses to optimize host protection. Created in BioRender. Sang, Y. (2026).
October 1, 2026 at 12:10 PM
plosbiology.org
Mounting an #immune response is energetically costly, and so host defenses are often influenced by internal metabolic states. This study identifies a gut-brain signaling mechanism in C. elegans, shaping pathogen avoidance and molecular immune responses.
🧪 #AcademicSky #hostPathogen
plos.io/3T9f6bi
Conceptual diagram for how NHR-68 integrates lipid metabolism with behavioral and molecular immunity. NHR-68 acts in the intestine to regulate linoleic acid homeostasis through control of fat-3 expression. Changes in intestinal lipid metabolism influence an AWC-dependent pathogen-avoidance circuit through currently unidentified intestine-to-neuron signaling mechanisms, enhancing survival during P. aeruginosa infection. In parallel, NHR-68 suppresses PMK-1/p38 MAPK and DAF-16/FOXO immune pathways, coordinating behavioral and molecular defenses to optimize host protection. Created in BioRender. Sang, Y. (2026).
September 30, 2026 at 8:10 AM
plosbiology.org
How do pathogens alter neuro-epidermal communication to compromise epidermal integrity? This study shows that Pseudomonas aeruginosa infection in C. elegans induces a neuropeptide-like factor, impairing epidermal lysosomes and collagen organization.
🧪 #MicroSky #hostPathogen
buff.ly/l2mgbTN
Schematic model of a neuro-epidermal signaling axis in which Pseudomonas aeruginosa PA14 exploits neuronal NSIF-1 to disrupt epidermal lysosomal function, compromise collagen integrity, and suppress host immunity in C. elegans. NSIF-1 acts as a neuronal secreted factor that mediates PA14-induced pathogenesis, inhibiting epidermal lysosomal activity via the transcription factor ELT-3.
September 25, 2026 at 4:02 PM
plosbiology.org
How do pathogens alter neuro-epidermal communication to compromise epidermal integrity? This study shows that Pseudomonas aeruginosa infection in C. elegans induces a neuropeptide-like factor, impairing epidermal lysosomes and collagen organization.
🧪 #MicroSky #hostPathogen
buff.ly/l2mgbTN
Schematic model of a neuro-epidermal signaling axis in which Pseudomonas aeruginosa PA14 exploits neuronal NSIF-1 to disrupt epidermal lysosomal function, compromise collagen integrity, and suppress host immunity in C. elegans. NSIF-1 acts as a neuronal secreted factor that mediates PA14-induced pathogenesis, inhibiting epidermal lysosomal activity via the transcription factor ELT-3.
September 24, 2026 at 12:01 PM
plosbiology.org
How do pathogens alter neuro-epidermal communication to compromise epidermal integrity? This study shows that Pseudomonas aeruginosa infection in C. elegans induces a neuropeptide-like factor, impairing epidermal lysosomes and collagen organization.
🧪 #MicroSky #hostPathogen
buff.ly/l2mgbTN
Schematic model of a neuro-epidermal signaling axis in which Pseudomonas aeruginosa PA14 exploits neuronal NSIF-1 to disrupt epidermal lysosomal function, compromise collagen integrity, and suppress host immunity in C. elegans. NSIF-1 acts as a neuronal secreted factor that mediates PA14-induced pathogenesis, inhibiting epidermal lysosomal activity via the transcription factor ELT-3.
September 23, 2026 at 8:00 AM
microbesinfo.bsky.social
🦠🔬 Scientists discovered an unusual #bacterium that can penetrate human #cells without relying on the typical invasion mechanisms used by many #bacterial #pathogens.

#Microbes #Bacteria #HostPathogen #Infections #Microsky via @sciencex.bsky.social

phys.org/news/2026-09...
An unusual bacterium that penetrates and lives inside human cells may offer a new drug target
Research underway in the lab of Rebecca Alexander, a professor in Wake Forest University's Department of Chemistry, is shedding light on an unusual human bacterium, Mycoplasma penetrans. Alexander's…
phys.org
September 13, 2026 at 1:30 AM
codythompson51.bsky.social
I just read this great article about my PhD advisor’s lab @TexasTech, and our many connections to the @CDCgov! I am glad to see collections-based #naturalhistory training intertwined with amazing #hostpathogen research, including #COVID19!

depts.ttu.edu/artsandscience…
December 1, 2024 at 11:54 PM
codythompson51.bsky.social
Calling all #publichealth scientists! In coordination w/@eurotaxonomy & @DiSSCoEU, we invite you to help us assess vouchering practices in #hostpathogen research. To participate, please visit#COVID19 #ViralMuse #naturalhistory #collectionsareessential

rb.gy/7ozrgv
December 1, 2024 at 11:54 PM
emanetoom.bsky.social
www.linkedin.com/posts/eman-e...
#microbiology #toxinantitoxin #genetics #bacterialpathogenesis #syntheticbiology #crispr #antimicrobialresistance #hostpathogen #phagetherapy #molecularbiology #researchcommunity | Eman Etoom
📍 Toxin-Antitoxin Systems: In microbiology, one of the most remarkable defense strategies doesn’t come from antibiotics — it comes from the bacteria themselves. Toxin-Antitoxin (TA) systems are genet...
www.linkedin.com
September 23, 2025 at 9:25 AM
irishimmunology.bsky.social
The ISI Annual Meeting 2026 is bringing leading voices in immunology to Dublin.

Host–Pathogen Immunology session featuring:
✨Silvia Melgar (UCC) and Matthew Hepworth (UoM)✨

📍UCD Belfield Campus
📆20–21 June
⏳Abstract deadline in 2 days!

#Immunology #ISI2026 #HostPathogen #ECR #ResearchCommunity
May 13, 2026 at 11:46 AM
anjalibhagirath.bsky.social
👋 New here on 🦋I’m Anjali , a #newPI at @Dalhousie University diving deep into host-pathogen interactions 🦠🌟. Looking forward to making new connections, sharing insights and reflections on the journey of being a new PI.
#hostpathogen #womeninSTEM #Immunology #Infections #researchlife #lifesciences
Husky chilling
November 18, 2024 at 3:28 PM
hansonmark.bsky.social
Evolutionary mechanisms underlying differences in the innate immune response to infection
mahansonresearch.weebly.com/blog/phd-swb...

#Drosophila #Evolution #Immunity #EvolBiol #Infection #HostPathogen

2/4
PhD studentship! Deadline Dec 3rd 2025
SWbio application link: https://www.exeter.ac.uk/study/pg-research/funding/phdfunding/fundedcentres/swbio/ For inquiries, please email: m.hanson@exeter.ac.uk Based in: University of Exeter, Penryn,...
mahansonresearch.weebly.com
November 15, 2025 at 3:35 PM
hansonmark.bsky.social
This is a really great overview of innate immunity concepts across organisms. A really fantastic conceptual read and one that I may add to my "required reading" list for training new students/lab members in concepts of innate immunity
#ImmunoSky #Immunology #Drosophila #Celegans #Mouse #HostPathogen
The conceptual foundations of innate immunity: Taking stock 30 years later
Recent studies revealed the existence of common principles of innate immune mechanisms across kingdoms and between the innate and adaptive branches of immunity in vertebrates. Lemaitre et al. discuss ...
www.cell.com
April 30, 2024 at 8:43 PM
juanvalenciabacca.bsky.social
currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

Our new article in Current Protocols is out: Microbiologists, immunologists, host-pathogen folks: this one’s for you 🧬🦠 #Klebsiella #HostPathogen #Microbiology
Huge thanks to my mentor @azmicro.bsky.social for the guidance and support!
Murine Models of Klebsiella pneumoniae Gastrointestinal Infection
Klebsiella pneumoniae (Kpn) is a Gram-negative opportunistic pathogen and a leading cause of hospital-acquired infections. The gastrointestinal (GI) tract serves as a critical site for Kpn colonizati....
currentprotocols.onlinelibrary.wiley.com
August 5, 2025 at 9:06 PM
achillebro.bsky.social
#immunology -st like me , think the immune system is complicated, until they start studying #hostpathogen interactions 😱
November 25, 2024 at 4:06 PM
virginiestevenin.bsky.social
We’re excited to share our latest work on bioRxiv:

"Salmonella exploits USP32 to coordinate Rab14 and Rab11 recycling pathways for intracellular survival" by Sapmaz et al

www.biorxiv.org/content/10.6...

#Salmonella #CellBiology #HostPathogen #Ubiquitin #bioRxiv
www.biorxiv.org
January 29, 2026 at 10:12 AM
iamshef.bsky.social
@cassandrakoh.bsky.social decoding virus-virus-host #metabolic interactions using #dengue & #wolbachia in #mosquitoes. #virus #hostpathogen

@pasteur.fr @salehlabparis.bsky.social
Lipids and Labyrinths: The metabolic maze of mosquito-virus encounters #MetabolismMondays - the Node
All the world's a metabolic dance, early career scientists are leading the way! Emerging perspectives in metabolism Dr. Cassandra KohBluesky:
thenode.biologists.com
December 23, 2025 at 2:36 AM
ervakeskin.bsky.social
Check out our newest publication in @cp-cellreports.bsky.social

#Mechanobiology #HostPathogen #Listeria
February 25, 2026 at 2:03 PM
pjcardona14.bsky.social
Thanks so
much for the invitation @irbbarcelona.org ! I hope this will raise the interest in #drosophila as a #experimentalmodel for #tuberculosis #hostpathogen #coevolution #sexualdimorphism #mdr #antibiotics #chemotherapy #toxicology and #regulatory @igtp.bsky.social
February 24, 2025 at 10:09 AM
pjcardona14.bsky.social
@cabd-upo-csic.bsky.social thanks so much for the invitation Tanja Dapta and for the inspiring talks on #microbiota #hostpathogen interactions and #mdr bacteria ! A seed for future collaborations! @igtp.bsky.social @scmimc.bsky.social #hugtip #uautonomabarcelona
cabd-upo-csic.bsky.social Centro Andaluz de Biología del Desarrollo @cabd-upo-csic.bsky.social · Feb 21
Amazing talk today at #CABDseminars with @pjcardona14.bsky.social explaining the studies on #tuberculosis using #fruitfly! Pere-Joan was invited by Tanja Dapa.

Thanks for coming!
February 21, 2025 at 5:12 PM
njmicrobe.bsky.social
Wang (Columbia) & Parker (Rutgers): New humanized mouse with autologous lung implants captures S. aureus infection dynamics: loss of human immune cells & cytokine surge. Bacterial stress-response essential for persistence go.njmicrobe.org/4NgYMT #Staph #Aureus #HostPathogen #MedicalMicrobiology
Staphylococcus aureus Research: Humanized Lung Models Unveil Host-Pathogen Dynamics
Staphylococcus aureus remains a formidable human pathogen, being a leading cause of bacterial-induced death, with significant concerns regarding antibiotic resistance and the current lack of an effective vaccine. A major hurdle in combating S. aureus is that it is a human-adapted pathogen, expressing virulence factors specific to human cellular receptors. This specificity limits the utility of traditional mouse models, which often fail to accurately replicate human-specific host responses to inf
go.njmicrobe.org
August 25, 2025 at 11:31 AM