#immunesignalling
✨New issue✨

Check out the latest in #Metabolism research from across all disciplines.

Read about #AMPK, #Cachexia, #ImmuneSignalling, #Microbiome, #NAD, #Nutrition, #TissueCrosstalk and many more topics! 🧪

www.nature.com/natmetab/vol...
January 30, 2026 at 4:02 PM
🧬Immune signalling can outlast receptor attachment. TRAM helps release MyD88 complexes from TLRs, sustaining inflammatory activity. A mechanistic study in macrophages.
doi.org/10.1038/s415...
#Immunology #immunesignalling #inflammation
TRAM promotes Toll-like-receptor-free myddosome signal transduction - Nature
TRAM is a regulator of myddosome assembly through dissociating MyD88 from the TLR–TIRAP complex to enable myddosome maturation and durable downstream signal transduction.
doi.org
September 24, 2026 at 5:57 PM