#jak2
Got my Jak 2 tee from @theyetee.com today, really happy with how this one came out! 😍

#jakanddaxter #jak2 #theyetee
November 3, 2026 at 2:41 PM
Even at the time I remember jak2 looking incredible and feeling like i was being subjected to a practical joke
Ratchet fans forever vindicated
November 3, 2026 at 4:50 AM
Two mutations tell the story: ESR1 (51% vs. 7%) favors long limbs and a slender body, while JAK2 (60% vs. 3%) enhances the red blood cells needed for sprinting. African sighthounds also retain genetic traces of ancient wolves.
November 3, 2026 at 4:50 PM
Concurrent inhibition of JAK2 and FLT3 by pacritinib is a promising therapeutic strategy for hepatocellular carcinoma #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-11231431/latest
November 2, 2026 at 11:01 PM
Hepatic alveolar echinococcosis-induced IL-23 maintains Th17/Treg homeostasis via the JAK2/STAT3 signaling pathway

📰 International immunopharmacology

#Zoonoses #OneHealth #InfectiousDiseases #PublicHealth

🔗 https://doi.org/10.1016/j.intimp.2026.117613
Hepatic alveolar echinococcosis-induced IL-23 maintains Th17/Treg homeostasis via the JAK2/STAT3 signaling pathway
Alveolar echinococcosis (AE), caused by Echinococcus multilocularis (E.multilocularis), is a life-threatening zoonotic disease with limited therapeutic options, and reliable biomarkers of disease a...
linkinghub.elsevier.com
November 1, 2026 at 5:01 PM
results from randomized Ruxobeat study of Rux vs BAT as 1st-line treatment for PV is out! Crossover to Rux was available after 6 months for BAT arm

-primary endpoint (CR) not superior
-better Hct control with Rux, poorer plt control
-both arms had JAK2 VAF reduction

www.nature.com/articles/s41...
October 23, 2026 at 3:28 PM
youtu.be/H8sM2sVUtLQ Omi Plays Jak 2 HD Remaster Part 18. Destroying Metal Head Eggs at the Strip Mine,and the Titan Suit at Dead Town Mission. #Jak #Daxter #JakAndDaxter #Jak2 #HD #Remaster #Playstation #Playstation3 #PS3 #NaughtyDog #Youtube #Gaming #Retro #RetroGames #RetroGaming #VideoGames
Omi Plays Jak 2 HD Remaster Part 18
YouTube video by Ominouslionheart
youtu.be
October 21, 2026 at 6:37 PM
New research finds the transcription factor B-cell lymphoma/leukemia 11B (BCL11B) is a key regulator of neuroinflammation & dopaminergic survival in models of #Parkinsons; BCL11B promotes neurotoxicity via JAK2/STAT3 activation, inhibition=neuroprotection
www.cell.com/iscience/ful...
October 22, 2026 at 4:00 PM
October 17, 2026 at 7:49 PM
What triggers #LiverInflammation in chronic hepatitis B?
#HBV replication impairs mitochondria, elevating #ROS and activating JAK2/STAT3 signaling, while antioxidants reduced inflammation in mice, revealing potential therapeutic targets.
#GenesAndDiseases: doi.org/10.1016/j.ge...
Activation of the Jak2/Stat3 pathway by ROS-dependent signaling cascades initiates hepatitis B virus-induced hepatic inflammatory responses
Chronic liver necroinflammation induced by hepatitis B virus (HBV) infection plays a major causative role in the development of end-stage liver diseas…
doi.org
October 20, 2026 at 9:00 AM
Check how, in this study, they revealed that CYBRD1 is a druggable transmembrane protein in HGSOC whose RUNX1-driven, Tyr252-dependent activation of JAK2/STAT3 promotes tumor progression and cisplatin resistance.
October 20, 2026 at 7:45 AM