Our work on Trichoplax locomotion and mechanosensing capabilities is out now in @currentbiology.bsky.social.
Congrats Marvin Leria & all co-authors!
authors.elsevier.com/c/1n8Ig3QW8S...
Congrats Marvin Leria & all co-authors!
authors.elsevier.com/c/1n8Ig3QW8S...
May 22, 2026 at 9:00 AM
Our work on Trichoplax locomotion and mechanosensing capabilities is out now in @currentbiology.bsky.social.
Congrats Marvin Leria & all co-authors!
authors.elsevier.com/c/1n8Ig3QW8S...
Congrats Marvin Leria & all co-authors!
authors.elsevier.com/c/1n8Ig3QW8S...
In their Review, @jontytownson.bsky.social and Cinzia Progida @biovitenskap.bsky.social discuss the emerging roles of the endoplasmic reticulum in mechanosensing and mechanotransduction.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
March 3, 2025 at 9:51 AM
In their Review, @jontytownson.bsky.social and Cinzia Progida @biovitenskap.bsky.social discuss the emerging roles of the endoplasmic reticulum in mechanosensing and mechanotransduction.
journals.biologists.com/jcs/article/...
journals.biologists.com/jcs/article/...
Out Now! Bacteria regulate collective behaviour by mechanosensing cell–cell collisions #MicroSky
Bacteria regulate collective behaviour by mechanosensing cell–cell collisions
Nature Microbiology, Published online: 06 October 2026; doi:10.1038/s41564-026-02505-1Density-dependent regulation of collective order through collision sensing and collision-induced reversals provides a navigational advantage to Pseudomonas aeruginosa during surface colonization and navigation through micromazes.
go.nature.com
October 6, 2026 at 10:03 AM
Out Now! Bacteria regulate collective behaviour by mechanosensing cell–cell collisions #MicroSky
Nature research paper: Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis.
https://go.nature.com/3GLyJ2e
https://go.nature.com/3GLyJ2e
Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis - Nature
Inhibition of a cardiac stroma-enriched mechanosensor, SRC—in concert with suppression of the TGFβ pathway—potentiates the reversal of fibroblast activation and alleviates contractile dysfunction in fibrotic hearts.
go.nature.com
May 4, 2025 at 10:00 AM
Nature research paper: Selective inhibition of stromal mechanosensing suppresses cardiac fibrosis.
https://go.nature.com/3GLyJ2e
https://go.nature.com/3GLyJ2e
Wow!
All joking aside, our cells have an orientation & polarity, fundamental to function. They incessantly monitor the environment around them. Mechanosensing is the way cells translate physical changes (gravity) to internal signals.
🧪We are literally earthlings, at the cellular & molecular level.
All joking aside, our cells have an orientation & polarity, fundamental to function. They incessantly monitor the environment around them. Mechanosensing is the way cells translate physical changes (gravity) to internal signals.
🧪We are literally earthlings, at the cellular & molecular level.
April 16, 2026 at 11:08 PM
Wow!
All joking aside, our cells have an orientation & polarity, fundamental to function. They incessantly monitor the environment around them. Mechanosensing is the way cells translate physical changes (gravity) to internal signals.
🧪We are literally earthlings, at the cellular & molecular level.
All joking aside, our cells have an orientation & polarity, fundamental to function. They incessantly monitor the environment around them. Mechanosensing is the way cells translate physical changes (gravity) to internal signals.
🧪We are literally earthlings, at the cellular & molecular level.
Bacteria regulate collective behaviour by mechanosensing cell–cell collisions www.nature.com/articles/s41... #jcampubs
Bacteria regulate collective behaviour by mechanosensing cell–cell collisions - Nature Microbiology
Density-dependent regulation of collective order through collision sensing and collision-induced reversals provides a navigational advantage to Pseudomonas aeruginosa during surface colonization and n...
www.nature.com
October 6, 2026 at 1:45 PM
Bacteria regulate collective behaviour by mechanosensing cell–cell collisions www.nature.com/articles/s41... #jcampubs
A bacterial lipid triggers membrane mechanosensing immunity in Arabidopsis https://www.biorxiv.org/content/10.64898/2026.04.23.720373v1
April 27, 2026 at 10:02 PM
A bacterial lipid triggers membrane mechanosensing immunity in Arabidopsis https://www.biorxiv.org/content/10.64898/2026.04.23.720373v1
"myosin inhibition can boost mechanosensing on cells cultured on dissipative matrices" 😮
Cell response to extracellular matrix viscous energy dissipation outweighs high-rigidity sensing
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Cell response to extracellular matrix viscous energy dissipation outweighs high-rigidity sensing
Viscosity blunts cell response to stiff matrices in agreement with a pull-and-hold model of molecular clutch-based mechanosensing.
www.science.org
November 16, 2024 at 6:11 AM
"myosin inhibition can boost mechanosensing on cells cultured on dissipative matrices" 😮
Perfect reason for my first post here. Super excited to see this work on PIEZO mechanosensing of the intestinal stem cell niche led by Meryem Baghdadi @vignjeviclab.bsky.social and Kim lab out in Science! Honored to have contributed to this story as 2nd author. 🎉
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance
Stem cells perceive and respond to biochemical and physical signals to maintain homeostasis. Yet, it remains unclear how stem cells sense mechanical signals from their niche in vivo. In this work, we ...
www.science.org
December 1, 2024 at 7:17 PM
Perfect reason for my first post here. Super excited to see this work on PIEZO mechanosensing of the intestinal stem cell niche led by Meryem Baghdadi @vignjeviclab.bsky.social and Kim lab out in Science! Honored to have contributed to this story as 2nd author. 🎉
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
www.nature.com/articles/s41...
Substrate curvature and stiffness equivalence in governing cell mechanosensing
Substrate curvature and stiffness equivalence in governing cell mechanosensing
August 25, 2026 at 11:18 AM
www.nature.com/articles/s41...
Substrate curvature and stiffness equivalence in governing cell mechanosensing
Substrate curvature and stiffness equivalence in governing cell mechanosensing
New layer of plant immune system
"membrane mechanosensing immunity (MSI), a third layer of cell surface immune signaling"
is nicely demonstrated by @julien-gronnier.bsky.social group
Cool finding! Congratulations!
"membrane mechanosensing immunity (MSI), a third layer of cell surface immune signaling"
is nicely demonstrated by @julien-gronnier.bsky.social group
Cool finding! Congratulations!
A bacterial lipid triggers membrane mechanosensing immunity in Arabidopsis https://www.biorxiv.org/content/10.64898/2026.04.23.720373v1
April 28, 2026 at 8:38 AM
New layer of plant immune system
"membrane mechanosensing immunity (MSI), a third layer of cell surface immune signaling"
is nicely demonstrated by @julien-gronnier.bsky.social group
Cool finding! Congratulations!
"membrane mechanosensing immunity (MSI), a third layer of cell surface immune signaling"
is nicely demonstrated by @julien-gronnier.bsky.social group
Cool finding! Congratulations!
Extracellular matrix-dependent regulation of Septin 7 in focal adhesions promotes mechanosensing and functional response in fibroblasts
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Extracellular matrix-dependent regulation of Septin 7 in focal adhesions promotes mechanosensing and functional response in fibroblasts
Fibroblasts are adherent cells that maintain tissue homeostasis by sensing and responding to the extracellular matrix (ECM). Focal adhesions (FAs) lin…
www.sciencedirect.com
November 12, 2024 at 6:52 PM
Extracellular matrix-dependent regulation of Septin 7 in focal adhesions promotes mechanosensing and functional response in fibroblasts
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance | Science www.science.org/doi/10.1126/...
PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance
Stem cells perceive and respond to biochemical and physical signals to maintain homeostasis. Yet, it remains unclear how stem cells sense mechanical signals from their niche in vivo. In this work, we ...
www.science.org
December 1, 2024 at 10:07 AM
PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance | Science www.science.org/doi/10.1126/...
I started to work on MscS-Like proteins 20 years ago, dreaming that they were involved in plant mechanotransduction. And it is becoming more & more clear that they are!
#plantscience 🧪
"DmMSL10 is crucial for mechanosensing, facilitating AP firing by generating a receptor potential (RP) amplitude."
#plantscience 🧪
"DmMSL10 is crucial for mechanosensing, facilitating AP firing by generating a receptor potential (RP) amplitude."
🍀🔬
MSL10 is a high-sensitivity mechanosensor in the tactile sense of the Venus flytrap @natcomms.nature.com from Toyota lab.
www.nature.com/articles/s41...
MSL10 is a high-sensitivity mechanosensor in the tactile sense of the Venus flytrap @natcomms.nature.com from Toyota lab.
www.nature.com/articles/s41...
October 7, 2025 at 4:48 PM
I started to work on MscS-Like proteins 20 years ago, dreaming that they were involved in plant mechanotransduction. And it is becoming more & more clear that they are!
#plantscience 🧪
"DmMSL10 is crucial for mechanosensing, facilitating AP firing by generating a receptor potential (RP) amplitude."
#plantscience 🧪
"DmMSL10 is crucial for mechanosensing, facilitating AP firing by generating a receptor potential (RP) amplitude."
Bacteria regulate collective behaviour by mechanosensing cell–cell collisions
doi.org/10.1038/s415...
doi.org/10.1038/s415...
Bacteria regulate collective behaviour by mechanosensing cell–cell collisions - Nature Microbiology
Density-dependent regulation of collective order through collision sensing and collision-induced reversals provides a navigational advantage to Pseudomonas aeruginosa during surface colonization and n...
doi.org
October 10, 2026 at 5:50 PM
Bacteria regulate collective behaviour by mechanosensing cell–cell collisions
doi.org/10.1038/s415...
doi.org/10.1038/s415...
PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance 🧪
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance
Stem cells perceive and respond to biochemical and physical signals to maintain homeostasis. Yet, it remains unclear how stem cells sense mechanical signals from their niche in vivo. In this work, we ...
www.science.org
November 29, 2024 at 6:47 AM
PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance 🧪
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Bubna-Litic, M., & Mayor, R. (2025). Beyond mechanosensing: How cells sense and shape their physical environment during development. Current opinion in cell biology, 94, 102514. #EpithelialMechanicsReview
buff.ly/Ea2ZoFg
buff.ly/Ea2ZoFg
September 4, 2025 at 7:00 AM
Bubna-Litic, M., & Mayor, R. (2025). Beyond mechanosensing: How cells sense and shape their physical environment during development. Current opinion in cell biology, 94, 102514. #EpithelialMechanicsReview
buff.ly/Ea2ZoFg
buff.ly/Ea2ZoFg
New OA Article: "Membrane remodelling mediates lipopeptide-induced immunity in Arabidopsis" rdcu.be/feoNF
Lipid-driven mechanism for immune activation by a bacterial lipopeptide. Perception at the cell membrane leads to deformation, mechanosensing and early signalling. #PlantScience
Lipid-driven mechanism for immune activation by a bacterial lipopeptide. Perception at the cell membrane leads to deformation, mechanosensing and early signalling. #PlantScience
April 20, 2026 at 12:14 PM
New OA Article: "Membrane remodelling mediates lipopeptide-induced immunity in Arabidopsis" rdcu.be/feoNF
Lipid-driven mechanism for immune activation by a bacterial lipopeptide. Perception at the cell membrane leads to deformation, mechanosensing and early signalling. #PlantScience
Lipid-driven mechanism for immune activation by a bacterial lipopeptide. Perception at the cell membrane leads to deformation, mechanosensing and early signalling. #PlantScience
Hi there! Check this really cool study led by my two #uofglasgow colleagues, Manuel Salmeron @manuelsalmeron.bsky.social and Marco Cantini @marcocantini.bsky.social, showing how microenvironment viscoelasticity dictates cell mechanosensing! 🧪👇
#CellularMicroenvironment
#Mechanobiology
#Biomaterials
#CellularMicroenvironment
#Mechanobiology
#Biomaterials
Interested in how #stemcells sense their environment? Check out our work showing how #ECMatrix viscosity regulates #mechanosensing and #differentiation 🧪 Led by @theglasgowcemi.bsky.social @uofglasgow.bsky.social in collaboration with IBEC @natureportfolio.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
N-cadherin crosstalk with integrin weakens the molecular clutch in response to surface viscosity - Nature Communications
The crosstalk between cell-cell and cell-matrix adhesions regulates stem cell fate. Here, the authors reveal a critical role for matrix viscosity in controlling this crosstalk, which they explain via ...
www.nature.com
November 20, 2024 at 9:24 PM
Hi there! Check this really cool study led by my two #uofglasgow colleagues, Manuel Salmeron @manuelsalmeron.bsky.social and Marco Cantini @marcocantini.bsky.social, showing how microenvironment viscoelasticity dictates cell mechanosensing! 🧪👇
#CellularMicroenvironment
#Mechanobiology
#Biomaterials
#CellularMicroenvironment
#Mechanobiology
#Biomaterials
A new study from the @maizel-lab.org, @dolfweijers.bsky.social, and @roelandmerks.bsky.social labs starting to unravel a role of SOSEKI proteins in cellular mechanosensing.
New preprint!
SOSEKI polarity proteins are mechanoresponsive integrators linking growth and tissue mechanics during lateral root formation. Their polarity marks growth boundaries and reorganises in response to mechanical alterations —reshaping how we think about axis formation.
tinyurl.com/28p7af2w
SOSEKI polarity proteins are mechanoresponsive integrators linking growth and tissue mechanics during lateral root formation. Their polarity marks growth boundaries and reorganises in response to mechanical alterations —reshaping how we think about axis formation.
tinyurl.com/28p7af2w
December 1, 2025 at 12:38 PM
A new study from the @maizel-lab.org, @dolfweijers.bsky.social, and @roelandmerks.bsky.social labs starting to unravel a role of SOSEKI proteins in cellular mechanosensing.
PIEZO ion channels are to human physiology as GLP-1 drugs are to treating many diseases
science.org/doi/10.1126/...
@science.org
science.org/doi/10.1126/...
@science.org
PIEZO-dependent mechanosensing is essential for intestinal stem cell fate decision and maintenance
Stem cells perceive and respond to biochemical and physical signals to maintain homeostasis. Yet, it remains unclear how stem cells sense mechanical signals from their niche in vivo. In this work, we ...
science.org
November 30, 2024 at 3:40 PM
PIEZO ion channels are to human physiology as GLP-1 drugs are to treating many diseases
science.org/doi/10.1126/...
@science.org
science.org/doi/10.1126/...
@science.org
New from Dr Gentzon Hall and colleagues in AJP Renal Physiology
CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes
pubmed.ncbi.nlm.nih....
CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes
pubmed.ncbi.nlm.nih....
March 13, 2025 at 2:52 AM
New from Dr Gentzon Hall and colleagues in AJP Renal Physiology
CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes
pubmed.ncbi.nlm.nih....
CRB2 Depletion Induces YAP Signaling and Disrupts Mechanosensing in Podocytes
pubmed.ncbi.nlm.nih....
🚨 Membrane Trafficking Seminar 🚨
Two great talks this Thursday!
📆 Thursday, April 24
🕔 5.00PM CET / 11.00AM EST
Hesso Farhan (Innsbruck)
Mechanosensing at the ER
Kelly Ten Hagen (NIH)
Secretory granule biogenesis in vivo
Details at
felixcampelo.wixsite.com/membranetraf...
Two great talks this Thursday!
📆 Thursday, April 24
🕔 5.00PM CET / 11.00AM EST
Hesso Farhan (Innsbruck)
Mechanosensing at the ER
Kelly Ten Hagen (NIH)
Secretory granule biogenesis in vivo
Details at
felixcampelo.wixsite.com/membranetraf...
MEMBRANE TRAFFICKING | Membrane Trafficking
felixcampelo.wixsite.com
April 21, 2025 at 5:08 PM
🚨 Membrane Trafficking Seminar 🚨
Two great talks this Thursday!
📆 Thursday, April 24
🕔 5.00PM CET / 11.00AM EST
Hesso Farhan (Innsbruck)
Mechanosensing at the ER
Kelly Ten Hagen (NIH)
Secretory granule biogenesis in vivo
Details at
felixcampelo.wixsite.com/membranetraf...
Two great talks this Thursday!
📆 Thursday, April 24
🕔 5.00PM CET / 11.00AM EST
Hesso Farhan (Innsbruck)
Mechanosensing at the ER
Kelly Ten Hagen (NIH)
Secretory granule biogenesis in vivo
Details at
felixcampelo.wixsite.com/membranetraf...