Normal Somitogenesis Despite the Absence of Snai1 in the Presomitic Mesoderm https://www.biorxiv.org/content/10.64898/2026.10.27.762210v1
October 28, 2026 at 8:32 PM
Normal Somitogenesis Despite the Absence of Snai1 in the Presomitic Mesoderm https://www.biorxiv.org/content/10.64898/2026.10.27.762210v1
RRID:AB_2534104 from @thermofishersci.bsky.social was used by authors in their bioRxiv paper. RRIDs improve reproducibility in scientific research. #STMpublishing #methodsmatter #OpenResearch
In utero barcoding of mouse mesoderm reveals the clonal architecture of organ mesenchyme
Read the full paper: In utero barcoding of mouse mesoderm reveals the clonal architecture of organ mesenchyme
doi.org
October 30, 2026 at 7:09 AM
RRID:AB_2534104 from @thermofishersci.bsky.social was used by authors in their bioRxiv paper. RRIDs improve reproducibility in scientific research. #STMpublishing #methodsmatter #OpenResearch
The authors included RRIDs in their in Nature Communications paper! We value the author's support of reproducibility. #methodsmatter #reproducibility #STMpublishing
Ectoderm tensile stress controls mesoderm internalization during embryo gastrulation - Nature Communications
The biomechanical basis for tissue folding during morphogenesis remains incompletely understood. Here they show that precisely balanced mechanical tension in tissues surrounding the future mesoderm is essential for its internalization during fruit fly gastrulation.
doi.org
October 30, 2026 at 7:07 AM
The authors included RRIDs in their in Nature Communications paper! We value the author's support of reproducibility. #methodsmatter #reproducibility #STMpublishing
Normal Somitogenesis Despite the Absence of Snai1 in the Presomitic Mesoderm https://www.biorxiv.org/content/10.64898/2026.10.27.762210v1
October 28, 2026 at 8:32 PM
Normal Somitogenesis Despite the Absence of Snai1 in the Presomitic Mesoderm https://www.biorxiv.org/content/10.64898/2026.10.27.762210v1
Vascular specification from diversified mesoderm culminates in endothelial convergence https://www.biorxiv.org/content/10.64898/2026.10.25.761646v1
October 27, 2026 at 5:31 PM
Vascular specification from diversified mesoderm culminates in endothelial convergence https://www.biorxiv.org/content/10.64898/2026.10.25.761646v1
Vascular specification from diversified mesoderm culminates in endothelial convergence https://www.biorxiv.org/content/10.64898/2026.10.25.761646v1
October 27, 2026 at 5:31 PM
Vascular specification from diversified mesoderm culminates in endothelial convergence https://www.biorxiv.org/content/10.64898/2026.10.25.761646v1
Vascular specification from diversified mesoderm culminates in endothelial convergence #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.25.761646v1
https://www.biorxiv.org/content/10.64898/2026.10.25.761646v1
October 27, 2026 at 8:00 PM
Vascular specification from diversified mesoderm culminates in endothelial convergence #SingleCell 🧪🧬🖥️
https://www.biorxiv.org/content/10.64898/2026.10.25.761646v1
https://www.biorxiv.org/content/10.64898/2026.10.25.761646v1
Mechano-metabolic control of multicellular morphogenesis
Bodineau, Pourquié, @mongeralab.bsky.social & co discuss how research into mechano-metabolic feedback loops during multicellular morphogenesis has the potential to drive major advances in our understanding of #DevBio. doi.org/10.1242/dev....
Bodineau, Pourquié, @mongeralab.bsky.social & co discuss how research into mechano-metabolic feedback loops during multicellular morphogenesis has the potential to drive major advances in our understanding of #DevBio. doi.org/10.1242/dev....
October 27, 2026 at 1:55 PM
Mechano-metabolic control of multicellular morphogenesis
Bodineau, Pourquié, @mongeralab.bsky.social & co discuss how research into mechano-metabolic feedback loops during multicellular morphogenesis has the potential to drive major advances in our understanding of #DevBio. doi.org/10.1242/dev....
Bodineau, Pourquié, @mongeralab.bsky.social & co discuss how research into mechano-metabolic feedback loops during multicellular morphogenesis has the potential to drive major advances in our understanding of #DevBio. doi.org/10.1242/dev....
Job ID: JPF10479
Extract: The Sparks Laboratory seeks a motivated Postdoctoral Scholar to investigate molecular and epigenetic mechanisms regulating early human pluripotent stem cell differentiation, focusing on neural crest and mesoderm lineage specification.
Extract: The Sparks Laboratory seeks a motivated Postdoctoral Scholar to investigate molecular and epigenetic mechanisms regulating early human pluripotent stem cell differentiation, focusing on neural crest and mesoderm lineage specification.
October 27, 2026 at 8:15 PM
Job ID: JPF10479
Extract: The Sparks Laboratory seeks a motivated Postdoctoral Scholar to investigate molecular and epigenetic mechanisms regulating early human pluripotent stem cell differentiation, focusing on neural crest and mesoderm lineage specification.
Extract: The Sparks Laboratory seeks a motivated Postdoctoral Scholar to investigate molecular and epigenetic mechanisms regulating early human pluripotent stem cell differentiation, focusing on neural crest and mesoderm lineage specification.
"Hey Wnt , how are ya?"
"Pretty good Yap, back at ya."
"You want to go to Mesoderm"
"Pretty good Yap, back at ya."
"You want to go to Mesoderm"
October 24, 2026 at 1:00 PM
"Hey Wnt , how are ya?"
"Pretty good Yap, back at ya."
"You want to go to Mesoderm"
"Pretty good Yap, back at ya."
"You want to go to Mesoderm"
The point in the sentence is a "conspicuous," meaning, "... there's almost no difference to the distances." But that is especially when we mean "vertebrates," as in the case of "vertebrate" (that is, the mesoderm, "the mesoderm of."
October 24, 2026 at 7:32 AM
The point in the sentence is a "conspicuous," meaning, "... there's almost no difference to the distances." But that is especially when we mean "vertebrates," as in the case of "vertebrate" (that is, the mesoderm, "the mesoderm of."
It is done. My magnum opus. My legacy.
October 20, 2026 at 9:51 PM
Years of tracking T+ cells now a preprint!
We show APLNR directs mesoderm migration in gastruloids and plays a role in spatial fate patterning.
🙏 @sseethar.bsky.social @alex-plum.bsky.social @heemskerklab.bsky.social @mattiaserra.bsky.social @squishycell.bsky.social
🔗 tinyurl.com/aplnrmeso
We show APLNR directs mesoderm migration in gastruloids and plays a role in spatial fate patterning.
🙏 @sseethar.bsky.social @alex-plum.bsky.social @heemskerklab.bsky.social @mattiaserra.bsky.social @squishycell.bsky.social
🔗 tinyurl.com/aplnrmeso
October 21, 2026 at 3:14 PM
Years of tracking T+ cells now a preprint!
We show APLNR directs mesoderm migration in gastruloids and plays a role in spatial fate patterning.
🙏 @sseethar.bsky.social @alex-plum.bsky.social @heemskerklab.bsky.social @mattiaserra.bsky.social @squishycell.bsky.social
🔗 tinyurl.com/aplnrmeso
We show APLNR directs mesoderm migration in gastruloids and plays a role in spatial fate patterning.
🙏 @sseethar.bsky.social @alex-plum.bsky.social @heemskerklab.bsky.social @mattiaserra.bsky.social @squishycell.bsky.social
🔗 tinyurl.com/aplnrmeso
Co-culturing CNS cells with a mesoderm organoid can create CNS organoids with microvascular networks and microglia to model neurovascular and neuroimmune crosstalk.
Drexel University patent application #US20260317705 #DrexelUniversity #Organoids
Drexel University patent application #US20260317705 #DrexelUniversity #Organoids
October 22, 2026 at 9:58 AM
Co-culturing CNS cells with a mesoderm organoid can create CNS organoids with microvascular networks and microglia to model neurovascular and neuroimmune crosstalk.
Drexel University patent application #US20260317705 #DrexelUniversity #Organoids
Drexel University patent application #US20260317705 #DrexelUniversity #Organoids
APLNR regulates directed migration to spatially pattern mesoderm in human gastruloids https://www.biorxiv.org/content/10.64898/2026.10.19.760207v1
October 20, 2026 at 10:30 PM
APLNR regulates directed migration to spatially pattern mesoderm in human gastruloids https://www.biorxiv.org/content/10.64898/2026.10.19.760207v1
APLNR regulates directed migration to spatially pattern mesoderm in human gastruloids https://www.biorxiv.org/content/10.64898/2026.10.19.760207v1
October 20, 2026 at 10:30 PM
APLNR regulates directed migration to spatially pattern mesoderm in human gastruloids https://www.biorxiv.org/content/10.64898/2026.10.19.760207v1
By differentiating naïve human pluripotent stem cells into extraembryonic mesoderm cells and trophoblast stem cells, we have discovered that female cells establish multiple hallmarks of X-chromosome inactivation.
October 22, 2026 at 12:12 PM
By differentiating naïve human pluripotent stem cells into extraembryonic mesoderm cells and trophoblast stem cells, we have discovered that female cells establish multiple hallmarks of X-chromosome inactivation.
🧪NEW DATA - Qkine LY294002 (Qk1102) validated in iPSC differentiation into endoderm and mesoderm.
View and buy LY294002 (Qk1102) > zurl.co/i3w7t
#stemcells #animalfree
View and buy LY294002 (Qk1102) > zurl.co/i3w7t
#stemcells #animalfree
October 21, 2026 at 7:44 AM
🧪NEW DATA - Qkine LY294002 (Qk1102) validated in iPSC differentiation into endoderm and mesoderm.
View and buy LY294002 (Qk1102) > zurl.co/i3w7t
#stemcells #animalfree
View and buy LY294002 (Qk1102) > zurl.co/i3w7t
#stemcells #animalfree
Mesoderm Explained: Heart Development, Cardiac Progenitor Cells and Embryology explained by Dr San Maharana
www.youtube.com/watch?v=Ocpf...
www.youtube.com/watch?v=Ocpf...
Dr. San Maharana Lecture: How the Human Heart Grows — The Incredible Power of Mesoderm!
YouTube video by San's Scientific Review
www.youtube.com
October 19, 2026 at 5:35 AM
Mesoderm Explained: Heart Development, Cardiac Progenitor Cells and Embryology explained by Dr San Maharana
www.youtube.com/watch?v=Ocpf...
www.youtube.com/watch?v=Ocpf...
RRIDs were included in this in Nature Communications paper. We value the author's support of reproducibility. #BetterScience #OpenResearch #OpenScience
Regulation of mRNA poly(A) tail length governs mammalian body plan formation in gastruloids - Nature Communications
How post-transcriptional mechanisms shape the mammalian body plan remains unclear. Here, the authors establish a single-cell CRISPR screening platform in gastruloids to identify Cnot8-dependent mRNA deadenylation as a driver of mesoderm patterning.
doi.org
October 18, 2026 at 7:00 AM
RRIDs were included in this in Nature Communications paper. We value the author's support of reproducibility. #BetterScience #OpenResearch #OpenScience
🧪NEW DATA - Qkine CHIR99021 (Qk1101) validated in iPSC differentiation into endoderm and mesoderm.
View and buy CHIR99021 (Qk1101) > zurl.co/GWcMa
View all Qkine small molecules > zurl.co/2WVOp
#stemcells #animalfree
View and buy CHIR99021 (Qk1101) > zurl.co/GWcMa
View all Qkine small molecules > zurl.co/2WVOp
#stemcells #animalfree
October 14, 2026 at 7:45 AM
🧪NEW DATA - Qkine CHIR99021 (Qk1101) validated in iPSC differentiation into endoderm and mesoderm.
View and buy CHIR99021 (Qk1101) > zurl.co/GWcMa
View all Qkine small molecules > zurl.co/2WVOp
#stemcells #animalfree
View and buy CHIR99021 (Qk1101) > zurl.co/GWcMa
View all Qkine small molecules > zurl.co/2WVOp
#stemcells #animalfree
TIL the brain is folded skin
October 6, 2026 at 9:25 PM
TIL the brain is folded skin
❤️ that the #NobelPrize brought the spotlight to #optogenetics. We use the same technique to study how cells move during development, like in this beautiful study by the Solnica-Krezel lab where they show mesoderm can influence endoderm convergent extension in 🐟!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
October 6, 2026 at 4:27 PM
❤️ that the #NobelPrize brought the spotlight to #optogenetics. We use the same technique to study how cells move during development, like in this beautiful study by the Solnica-Krezel lab where they show mesoderm can influence endoderm convergent extension in 🐟!
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Giada Mura, Michiel Tawdarous, Patrícia Duarte, Florian Mueller, Alexandre Mayran, Ingo Burtscher, Heiko Lickert, Shahragim Tajbakhsh: Engineered dual-gastruloid model for foregut-pharyngeal mesoderm co-development https://pasteur.hal.science/pasteur-05780999v1 [sdv]
October 7, 2026 at 3:00 AM
Giada Mura, Michiel Tawdarous, Patrícia Duarte, Florian Mueller, Alexandre Mayran, Ingo Burtscher, Heiko Lickert, Shahragim Tajbakhsh: Engineered dual-gastruloid model for foregut-pharyngeal mesoderm co-development https://pasteur.hal.science/pasteur-05780999v1 [sdv]