Eleonora Torre, et al.: Validation of differentiated sinoatrial-like hiPSCs as a model of native sinus node myocytes https://hal.science/hal-05844609v1 [sdv]
November 2, 2026 at 3:00 AM
Eleonora Torre, et al.: Validation of differentiated sinoatrial-like hiPSCs as a model of native sinus node myocytes https://hal.science/hal-05844609v1 [sdv]
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Smartass Publishers
www.jagerpress.com
November 3, 2026 at 5:10 PM
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
CRV Science Labs ⚗️
🧬 How Independent Myosin II Duplications, Troponin-Absent Myocytes, and Ancestral Collagen IV Support the Ctenophora-First Hypothesis — Synthesizing 1.58 Mb across 32 Development and Untouched Reser…
https://crvscience.com/labs/discoveries/ctenophora-first-muscle-epithelia-tier3
🧬 How Independent Myosin II Duplications, Troponin-Absent Myocytes, and Ancestral Collagen IV Support the Ctenophora-First Hypothesis — Synthesizing 1.58 Mb across 32 Development and Untouched Reser…
https://crvscience.com/labs/discoveries/ctenophora-first-muscle-epithelia-tier3
CRV Science Labs ⚗️
🧬 How Independent Myosin II Duplications, Troponin-Absent Myocytes, and Ancestral Collagen IV Support the Ctenophora-First Hypothesis — Synthesizing 1.58 Mb across 32 Development and Untouched Reserve cohorts (64 metazoan and holozoan taxa) demonstrates that ctenophores evolved …
crvscience.com
November 3, 2026 at 11:40 AM
CRV Science Labs ⚗️
🧬 How Independent Myosin II Duplications, Troponin-Absent Myocytes, and Ancestral Collagen IV Support the Ctenophora-First Hypothesis — Synthesizing 1.58 Mb across 32 Development and Untouched Reser…
https://crvscience.com/labs/discoveries/ctenophora-first-muscle-epithelia-tier3
🧬 How Independent Myosin II Duplications, Troponin-Absent Myocytes, and Ancestral Collagen IV Support the Ctenophora-First Hypothesis — Synthesizing 1.58 Mb across 32 Development and Untouched Reser…
https://crvscience.com/labs/discoveries/ctenophora-first-muscle-epithelia-tier3
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Smartass Publishers
www.jagerpress.com
October 30, 2026 at 4:36 PM
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
RRIDs were included in this in Nature Cardiovascular Research paper. We value the author's support of reproducibility. #ReproducibleResearch #reproducibility #STMpublishing
Cardiomyocyte-expressed TGFβ programs early heart maturation and adult myocyte identity - Nature Cardiovascular Research
Minerath et al. show that cardiomyocyte-derived TGFβ orchestrates a developmental signaling network that is essential for heart maturation. By communicating with non-myocytes, TGFβ promotes cardiomyocyte identity, whereas its loss disrupts fibroblast maturation and activates skeletal muscle gene programs in cardiomyocytes.
doi.org
October 30, 2026 at 7:08 AM
RRIDs were included in this in Nature Cardiovascular Research paper. We value the author's support of reproducibility. #ReproducibleResearch #reproducibility #STMpublishing
A team at Yale Medicine identified a previously unknown mechanism by a nutrient in red meat, may increase #inflammation. During their #sepsis research, they found the #molecule L-carnitine was worsening outcomes, causing an inflammatory cascade.
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
The pyrin inflammasome senses OCTN2-mediated uptake of extracellular ʟ-carnitine from muscle injury or ingestion
ʟ-Carnitine is a nonproteinogenic amino acid highly abundant in myocytes, and both
excess ingestion of myocytes and myocyte necrosis are associated with systemic inflammation.
Here, we find that the p...
www.cell.com
October 26, 2026 at 4:28 PM
A team at Yale Medicine identified a previously unknown mechanism by a nutrient in red meat, may increase #inflammation. During their #sepsis research, they found the #molecule L-carnitine was worsening outcomes, causing an inflammatory cascade.
www.cell.com/cell/abstrac...
www.cell.com/cell/abstrac...
Member publication alert:
Cardiomyocyte-expressed TGFβ programs early heart maturation and adult myocyte identity
www.nature.com/articles/s44...
Cardiomyocyte-expressed TGFβ programs early heart maturation and adult myocyte identity
www.nature.com/articles/s44...
Cardiomyocyte-expressed TGFβ programs early heart maturation and adult myocyte identity - Nature Cardiovascular Research
Minerath et al. show that cardiomyocyte-derived TGFβ orchestrates a developmental signaling network that is essential for heart maturation. By communicating with non-myocytes, TGFβ promotes cardiomyoc...
www.nature.com
October 25, 2026 at 3:56 PM
Member publication alert:
Cardiomyocyte-expressed TGFβ programs early heart maturation and adult myocyte identity
www.nature.com/articles/s44...
Cardiomyocyte-expressed TGFβ programs early heart maturation and adult myocyte identity
www.nature.com/articles/s44...
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Smartass Publishers
www.jagerpress.com
October 20, 2026 at 7:39 PM
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Now online! The pyrin inflammasome senses OCTN2-mediated uptake of extracellular ʟ-carnitine from muscle injury or ingestion
The pyrin inflammasome senses OCTN2-mediated uptake of extracellular ʟ-carnitine from muscle injury or ingestion
ʟ-Carnitine is a nonproteinogenic amino acid highly abundant in myocytes, and both excess ingestion of myocytes and myocyte necrosis are associated with systemic inflammation. Here, we find that the pyrin inflammasome senses extracellular ʟ-carnitine through the high-affinity carnitine transporter OCTN2 (SLC22A5) and this leads to IL-1β-mediated inflammation. Our findings position OCTN2 as a potential target to reduce inflammation from exogenous or endogenous sources of extracellular ʟ-carnitine.
dlvr.it
October 19, 2026 at 2:59 PM
Now online! The pyrin inflammasome senses OCTN2-mediated uptake of extracellular ʟ-carnitine from muscle injury or ingestion
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Smartass Publishers
www.jagerpress.com
October 16, 2026 at 8:51 AM
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Excitation-contraction coupling plasticity is revealed upon RyR2 depletion in adult mouse ventricular myocytes https://www.biorxiv.org/content/10.64898/2026.10.07.755981v1
October 15, 2026 at 6:01 AM
Excitation-contraction coupling plasticity is revealed upon RyR2 depletion in adult mouse ventricular myocytes https://www.biorxiv.org/content/10.64898/2026.10.07.755981v1
Excitation-contraction coupling plasticity is revealed upon RyR2 depletion in adult mouse ventricular myocytes https://www.biorxiv.org/content/10.64898/2026.10.07.755981v1
October 15, 2026 at 6:01 AM
Excitation-contraction coupling plasticity is revealed upon RyR2 depletion in adult mouse ventricular myocytes https://www.biorxiv.org/content/10.64898/2026.10.07.755981v1
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Smartass Publishers
www.jagerpress.com
October 13, 2026 at 5:29 PM
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Smartass Publishers
www.jagerpress.com
October 6, 2026 at 8:44 PM
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Smartass Publishers
www.jagerpress.com
October 4, 2026 at 8:21 PM
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Pterostilbene suppresses intracellular lipid accumulation in C2C12 myocytes via PPARδ stabilization www.sciencedirect.com/science/arti...
www.sciencedirect.com
October 4, 2026 at 4:31 AM
Pterostilbene suppresses intracellular lipid accumulation in C2C12 myocytes via PPARδ stabilization www.sciencedirect.com/science/arti...
I had a discussion on here a while ago with an AI fan, and it tried to summarise one of my own research papers.
It misunderstood and claimed the paper was about Myocytes rather than Monocytes. That is a huge fail.
If it made a similar medical misunderstanding, it could kill someone.
It misunderstood and claimed the paper was about Myocytes rather than Monocytes. That is a huge fail.
If it made a similar medical misunderstanding, it could kill someone.
September 30, 2026 at 6:08 PM
I had a discussion on here a while ago with an AI fan, and it tried to summarise one of my own research papers.
It misunderstood and claimed the paper was about Myocytes rather than Monocytes. That is a huge fail.
If it made a similar medical misunderstanding, it could kill someone.
It misunderstood and claimed the paper was about Myocytes rather than Monocytes. That is a huge fail.
If it made a similar medical misunderstanding, it could kill someone.
Although the light microscopic findings of rounded, variably-sized myocytes and interstitial connective tissue would be quite abnormal for a quadriceps biopsy, this is the normal histologic appearance of extraocular muscles.
September 30, 2026 at 10:41 PM
Although the light microscopic findings of rounded, variably-sized myocytes and interstitial connective tissue would be quite abnormal for a quadriceps biopsy, this is the normal histologic appearance of extraocular muscles.
ICB Throwback Axolotl Thursday
#Morphological, #Biochemical and #Immunohistochemical Studies on Heart Development in Cardiac Mutant #Axolotls, Ambystoma mexicanum
LARRY F. LEMANSKI
doi.org/10.1093/icb/...
#amphibians #science
#Morphological, #Biochemical and #Immunohistochemical Studies on Heart Development in Cardiac Mutant #Axolotls, Ambystoma mexicanum
LARRY F. LEMANSKI
doi.org/10.1093/icb/...
#amphibians #science
October 1, 2026 at 11:38 AM
ICB Throwback Axolotl Thursday
#Morphological, #Biochemical and #Immunohistochemical Studies on Heart Development in Cardiac Mutant #Axolotls, Ambystoma mexicanum
LARRY F. LEMANSKI
doi.org/10.1093/icb/...
#amphibians #science
#Morphological, #Biochemical and #Immunohistochemical Studies on Heart Development in Cardiac Mutant #Axolotls, Ambystoma mexicanum
LARRY F. LEMANSKI
doi.org/10.1093/icb/...
#amphibians #science
Calcium doesn’t stabilize cardiac myocytes in hyperK
-Ca restores Ca dependent propagation
-Doesn’t matter clinically as Ca2+ will reverse hyperK induced ECG changes
-Ca2+ is still the treatment of choice in hyperK w/ significant ECG changes like QRS widening
youtube.com/shorts/9wRbG...
#EMIMCC
-Ca restores Ca dependent propagation
-Doesn’t matter clinically as Ca2+ will reverse hyperK induced ECG changes
-Ca2+ is still the treatment of choice in hyperK w/ significant ECG changes like QRS widening
youtube.com/shorts/9wRbG...
#EMIMCC
Calcium in HyperK #emergencymedicine #criticalcare
YouTube video by EMSwami
youtube.com
September 30, 2026 at 2:32 PM
Calcium doesn’t stabilize cardiac myocytes in hyperK
-Ca restores Ca dependent propagation
-Doesn’t matter clinically as Ca2+ will reverse hyperK induced ECG changes
-Ca2+ is still the treatment of choice in hyperK w/ significant ECG changes like QRS widening
youtube.com/shorts/9wRbG...
#EMIMCC
-Ca restores Ca dependent propagation
-Doesn’t matter clinically as Ca2+ will reverse hyperK induced ECG changes
-Ca2+ is still the treatment of choice in hyperK w/ significant ECG changes like QRS widening
youtube.com/shorts/9wRbG...
#EMIMCC
Ventricular arrhythmias are caused by ischaemia, microvascular thrombosis, inflammation, & viral invasion of myocytes or the conduction system. Inflammation also exacerbates electrical instability and ion channel malfunction. Ventricular arrhythmias are also facilitated by hyperadrenergic conditions
September 28, 2026 at 6:43 PM
Ventricular arrhythmias are caused by ischaemia, microvascular thrombosis, inflammation, & viral invasion of myocytes or the conduction system. Inflammation also exacerbates electrical instability and ion channel malfunction. Ventricular arrhythmias are also facilitated by hyperadrenergic conditions
immune-mediated damage takes place through a hyperinflammatory response—a cytokine storm—that causes the infiltration of T-cells and activation of macrophages, triggering inflammation of the myocytes.
→ endothelial injury increases ischaemia and thrombotic events, promoting cardiac injury.
#medsky
→ endothelial injury increases ischaemia and thrombotic events, promoting cardiac injury.
#medsky
September 28, 2026 at 1:01 PM
immune-mediated damage takes place through a hyperinflammatory response—a cytokine storm—that causes the infiltration of T-cells and activation of macrophages, triggering inflammation of the myocytes.
→ endothelial injury increases ischaemia and thrombotic events, promoting cardiac injury.
#medsky
→ endothelial injury increases ischaemia and thrombotic events, promoting cardiac injury.
#medsky
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Smartass Publishers
www.jagerpress.com
September 27, 2026 at 4:42 PM
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html
Smartass Publishers
www.jagerpress.com
September 22, 2026 at 8:59 AM
Myocytes are the cells that make up our muscle fibre, because I haven’t run for so long, my legs now feel like they are on fire! : www.jagerpress.com/poems.html