The combination of hematuria, proteinuria, and casts on a UA is considered “nephritic sediment”. The presence of the sediment helps to localize the pathology to the glomerulus.
August 25, 2026 at 9:00 PM
The combination of hematuria, proteinuria, and casts on a UA is considered “nephritic sediment”. The presence of the sediment helps to localize the pathology to the glomerulus.
June 15, 2026 at 2:07 AM
Monoclonal nephritic factors reveal insights into C3 convertase dynamics and dysregulation https://www.biorxiv.org/content/10.64898/2026.06.11.731599v1
June 13, 2026 at 12:16 AM
Monoclonal nephritic factors reveal insights into C3 convertase dynamics and dysregulation https://www.biorxiv.org/content/10.64898/2026.06.11.731599v1
Monoclonal nephritic factors reveal insights into C3 convertase dynamics and dysregulation https://www.biorxiv.org/content/10.64898/2026.06.11.731599v1
June 13, 2026 at 12:16 AM
Monoclonal nephritic factors reveal insights into C3 convertase dynamics and dysregulation https://www.biorxiv.org/content/10.64898/2026.06.11.731599v1
8/10
Consensus:
The indications can guide you for the biopsy:
🔬Age <30 or >60
🔬Active urine sediment
🔬AKI/Acute Nephritic presentation/RPRF
🔬Atypical symptoms: arthritis / rash
🔬Better to avoid in DM pts with CKD & proteinuria without atypical features
Consensus:
The indications can guide you for the biopsy:
🔬Age <30 or >60
🔬Active urine sediment
🔬AKI/Acute Nephritic presentation/RPRF
🔬Atypical symptoms: arthritis / rash
🔬Better to avoid in DM pts with CKD & proteinuria without atypical features
June 3, 2026 at 12:10 PM
8/10
Consensus:
The indications can guide you for the biopsy:
🔬Age <30 or >60
🔬Active urine sediment
🔬AKI/Acute Nephritic presentation/RPRF
🔬Atypical symptoms: arthritis / rash
🔬Better to avoid in DM pts with CKD & proteinuria without atypical features
Consensus:
The indications can guide you for the biopsy:
🔬Age <30 or >60
🔬Active urine sediment
🔬AKI/Acute Nephritic presentation/RPRF
🔬Atypical symptoms: arthritis / rash
🔬Better to avoid in DM pts with CKD & proteinuria without atypical features
Dunston is wearing a disguise, and attempting to infiltrate a cave once more, he is caught viewing a wrinkled skin detector as a nephritic dumpster boy
April 22, 2026 at 4:36 PM
Dunston is wearing a disguise, and attempting to infiltrate a cave once more, he is caught viewing a wrinkled skin detector as a nephritic dumpster boy
nephritic.
The term used in the Vatican, again in Renaissance times, to refer to ceremonies performed to induct a papal ‘nephew’ as a cardinal.
The term used in the Vatican, again in Renaissance times, to refer to ceremonies performed to induct a papal ‘nephew’ as a cardinal.
April 12, 2026 at 8:56 PM
nephritic.
The term used in the Vatican, again in Renaissance times, to refer to ceremonies performed to induct a papal ‘nephew’ as a cardinal.
The term used in the Vatican, again in Renaissance times, to refer to ceremonies performed to induct a papal ‘nephew’ as a cardinal.
Daily Pearl(s):
Signs of GPA
The combination of an acute kidney injury with a nephritic sediment and any upper respiratory symptoms (sinusitis, otitis, nasal deformity) should immediately raise suspicion for GPA.
Signs of GPA
The combination of an acute kidney injury with a nephritic sediment and any upper respiratory symptoms (sinusitis, otitis, nasal deformity) should immediately raise suspicion for GPA.
April 11, 2026 at 9:00 PM
Daily Pearl(s):
Signs of GPA
The combination of an acute kidney injury with a nephritic sediment and any upper respiratory symptoms (sinusitis, otitis, nasal deformity) should immediately raise suspicion for GPA.
Signs of GPA
The combination of an acute kidney injury with a nephritic sediment and any upper respiratory symptoms (sinusitis, otitis, nasal deformity) should immediately raise suspicion for GPA.
Management starts with a comprehensive complement workup: C3, C3c, Bb, C4, nephritic factors, soluble C5b-9, properdin, factor H, CH50/APH50, and genotyping. Treatment is activity-guided: supportive care → MMF/steroids → anti-complement therapy.
April 10, 2026 at 1:51 PM
Management starts with a comprehensive complement workup: C3, C3c, Bb, C4, nephritic factors, soluble C5b-9, properdin, factor H, CH50/APH50, and genotyping. Treatment is activity-guided: supportive care → MMF/steroids → anti-complement therapy.
Acquired factors matter equally: C3 nephritic factors (present in 50–80% of patients) stabilize C3 convertase and drive uncontrolled activation. Highly stabilizing activity correlates with rapid disease progression.
April 10, 2026 at 1:51 PM
Acquired factors matter equally: C3 nephritic factors (present in 50–80% of patients) stabilize C3 convertase and drive uncontrolled activation. Highly stabilizing activity correlates with rapid disease progression.
Rapidly progressive GN. Nephrotic vs nephritic presentations. Emerging diagnostic tools.
Are your management strategies aligned with the latest evidence?
📚 bit.ly/4r5CHV8
#EvidenceBasedMedicine #Nephrology #RenalEducation #KidneyProfessionals #CME #MedTwitter #FOAMed
Are your management strategies aligned with the latest evidence?
📚 bit.ly/4r5CHV8
#EvidenceBasedMedicine #Nephrology #RenalEducation #KidneyProfessionals #CME #MedTwitter #FOAMed
CaseHippo
One platform for interactive learning, engagement and collaborative knowledge
bit.ly
March 11, 2026 at 12:02 PM
Rapidly progressive GN. Nephrotic vs nephritic presentations. Emerging diagnostic tools.
Are your management strategies aligned with the latest evidence?
📚 bit.ly/4r5CHV8
#EvidenceBasedMedicine #Nephrology #RenalEducation #KidneyProfessionals #CME #MedTwitter #FOAMed
Are your management strategies aligned with the latest evidence?
📚 bit.ly/4r5CHV8
#EvidenceBasedMedicine #Nephrology #RenalEducation #KidneyProfessionals #CME #MedTwitter #FOAMed
unmistakable leak through those nephritic filters
March 3, 2026 at 3:25 PM
unmistakable leak through those nephritic filters
Case report: A nephritic puzzle: C3-dominant glomerulonephritis as a sentinel of hidden autoinflammatory disease
#openaccess
#nephsky
#openaccess
#nephsky
A nephritic puzzle: C3-dominant glomerulonephritis as a sentinel of hidden autoinflammatory disease - Pediatric Nephrology
Membranoproliferative glomerulonephritis (MPGN) is among the most challenging glomerulonephritides to diagnose and manage, given its clinico-immunopathologic heterogeneity. Although recent advances…
buff.ly
February 28, 2026 at 6:03 PM
Case report: A nephritic puzzle: C3-dominant glomerulonephritis as a sentinel of hidden autoinflammatory disease
#openaccess
#nephsky
#openaccess
#nephsky
Lecture 10: Glomerular Diseases — Renal
Glomerular diseases produce recognizable clinical patterns that guide differential diagnosis and management.
https://hibbertmed.com/lectures/year2/unit2.1_renal/lecture_10_glomerular_diseases
Glomerular diseases produce recognizable clinical patterns that guide differential diagnosis and management.
https://hibbertmed.com/lectures/year2/unit2.1_renal/lecture_10_glomerular_diseases
February 20, 2026 at 5:34 PM
Lecture 10: Glomerular Diseases — Renal
Glomerular diseases produce recognizable clinical patterns that guide differential diagnosis and management.
https://hibbertmed.com/lectures/year2/unit2.1_renal/lecture_10_glomerular_diseases
Glomerular diseases produce recognizable clinical patterns that guide differential diagnosis and management.
https://hibbertmed.com/lectures/year2/unit2.1_renal/lecture_10_glomerular_diseases
Most patients with IgAN present with some or all elements of the nephritic syndrome, ie, nonvisible hematuria, proteinuria, impaired kidney function, and hypertension.
January 26, 2026 at 9:46 PM
Most patients with IgAN present with some or all elements of the nephritic syndrome, ie, nonvisible hematuria, proteinuria, impaired kidney function, and hypertension.
📃Scientific paper: Daratumumab therapy in a pediatric case of C3 nephritic factor-positive proliferative glomerulonephritis with monoclonal IgG deposits
Ref.: Springer, 2024
➡️ Continued on ES/IODE
Ref.: Springer, 2024
➡️ Continued on ES/IODE
January 26, 2026 at 4:00 PM
📃Scientific paper: Daratumumab therapy in a pediatric case of C3 nephritic factor-positive proliferative glomerulonephritis with monoclonal IgG deposits
Ref.: Springer, 2024
➡️ Continued on ES/IODE
Ref.: Springer, 2024
➡️ Continued on ES/IODE
T1c
Inclusion criteria:
⭕adolescents (ages 12–17)
⭕adults (> 18 years)
⭕biopsy proven C3 GN or primary IC-MPGN
⭕evidence of 🤸🏽♀️active disease: 2+ or higher on C3 IF staining
⭕➕biomarkers if adolescent
‼️⬆️Plasma sC5-9
‼️⬇️serum C3
‼️hematuria
‼️C3 nephritic factor
#NephJC
Inclusion criteria:
⭕adolescents (ages 12–17)
⭕adults (> 18 years)
⭕biopsy proven C3 GN or primary IC-MPGN
⭕evidence of 🤸🏽♀️active disease: 2+ or higher on C3 IF staining
⭕➕biomarkers if adolescent
‼️⬆️Plasma sC5-9
‼️⬇️serum C3
‼️hematuria
‼️C3 nephritic factor
#NephJC
January 14, 2026 at 2:18 AM
T1c
Inclusion criteria:
⭕adolescents (ages 12–17)
⭕adults (> 18 years)
⭕biopsy proven C3 GN or primary IC-MPGN
⭕evidence of 🤸🏽♀️active disease: 2+ or higher on C3 IF staining
⭕➕biomarkers if adolescent
‼️⬆️Plasma sC5-9
‼️⬇️serum C3
‼️hematuria
‼️C3 nephritic factor
#NephJC
Inclusion criteria:
⭕adolescents (ages 12–17)
⭕adults (> 18 years)
⭕biopsy proven C3 GN or primary IC-MPGN
⭕evidence of 🤸🏽♀️active disease: 2+ or higher on C3 IF staining
⭕➕biomarkers if adolescent
‼️⬆️Plasma sC5-9
‼️⬇️serum C3
‼️hematuria
‼️C3 nephritic factor
#NephJC
Nephrotic vs Nephritic Syndrome mohammadvazirimedicaleducation.wordpress.com/2026/01/12/n...
Nephrotic vs Nephritic Syndrome
Visit the post for more.
mohammadvazirimedicaleducation.wordpress.com
January 12, 2026 at 5:01 PM
Nephrotic vs Nephritic Syndrome mohammadvazirimedicaleducation.wordpress.com/2026/01/12/n...
📃Scientific paper: Daratumumab therapy in a pediatric case of C3 nephritic factor-positive proliferative glomerulonephritis with monoclonal IgG deposits
Ref.: Springer, 2024
➡️ Continued on ES/IODE
Ref.: Springer, 2024
➡️ Continued on ES/IODE
January 10, 2026 at 4:00 PM
📃Scientific paper: Daratumumab therapy in a pediatric case of C3 nephritic factor-positive proliferative glomerulonephritis with monoclonal IgG deposits
Ref.: Springer, 2024
➡️ Continued on ES/IODE
Ref.: Springer, 2024
➡️ Continued on ES/IODE
As a diabetic (well-controlled, and close to remission), keeping nephritic function has been a big focus of my docs and me.
I wish you luck….
I wish you luck….
January 7, 2026 at 5:20 AM
As a diabetic (well-controlled, and close to remission), keeping nephritic function has been a big focus of my docs and me.
I wish you luck….
I wish you luck….
Aetiology of acute/subacute nephritic syndrome: results from kidney biopsy registries in Japan and Europe
Aetiology of acute/subacute nephritic syndrome: results from kidney biopsy registries in Japan and Europe - PubMed
The most common underlying causes of acute/subacute nephritic syndrome are ANCA-associated vasculitis, IgA nephropathy/vasculitis and acute interstitial nephritis. This study highlights both similarities and differences in the spectrum of underlying diagnoses and clinical presentations across ages, …
pubmed.ncbi.nlm.nih.gov
November 12, 2025 at 11:21 PM
Aetiology of acute/subacute nephritic syndrome: results from kidney biopsy registries in Japan and Europe
Yesterday I was in ER because I had a nephritic colic and despite they gave me medication for a week my biggest issue is that i wont be able to consume coffee, life has no meaning without coffee
April 13, 2025 at 5:13 AM
Yesterday I was in ER because I had a nephritic colic and despite they gave me medication for a week my biggest issue is that i wont be able to consume coffee, life has no meaning without coffee
A Case Report and Literature Review of ANCA-Associated Vasculitis and Lupus Nephritis Overlap: Lessons in Management karger.com/gdz/article/...
A Case Report and Literature Review of ANCA-Associated Vasculitis and Lupus Nephritis Overlap: Lessons in Management
Abstract. Introduction: ANCA-associated vasculitis (AAV) and lupus nephritis (LN) are distinct disease processes that both cause a nephritic picture with acute renal failure, but have different pathop...
karger.com
March 29, 2025 at 7:23 PM
A Case Report and Literature Review of ANCA-Associated Vasculitis and Lupus Nephritis Overlap: Lessons in Management karger.com/gdz/article/...
A Case Report and Literature Review of ANCA-Associated Vasculitis and #Lupus Nephritis Overlap: Lessons in Management
karger.com/gdz/article/...
karger.com/gdz/article/...
A Case Report and Literature Review of ANCA-Associated Vasculitis and Lupus Nephritis Overlap: Lessons in Management
Abstract. Introduction: ANCA-associated vasculitis (AAV) and lupus nephritis (LN) are distinct disease processes that both cause a nephritic picture with acute renal failure, but have different pathop...
karger.com
March 18, 2025 at 8:57 AM
A Case Report and Literature Review of ANCA-Associated Vasculitis and #Lupus Nephritis Overlap: Lessons in Management
karger.com/gdz/article/...
karger.com/gdz/article/...
Addressing Risk Factors That Drive CKD Risk in Lupus Nephritis - Physician's Weekly - goo.gl/alerts/TdXMgN #GoogleAlerts
Addressing Risk Factors That Drive CKD Risk in Lupus Nephritis - Physician's Weekly
Research shows multiple factors drive CKD risk in lupus nephritis, including nephritic flares, baseline hypertension, renal impairment, and proteinuria.
goo.gl
March 14, 2025 at 1:00 PM
Addressing Risk Factors That Drive CKD Risk in Lupus Nephritis - Physician's Weekly - goo.gl/alerts/TdXMgN #GoogleAlerts