Amoxicillin crystalluria during endocarditis treatment
doi.org/10.1016/j.kint.2024.07.029
#KINephrologyImage #MedSky #NephSky #nephrotoxicity
doi.org/10.1016/j.kint.2024.07.029
#KINephrologyImage #MedSky #NephSky #nephrotoxicity
January 23, 2025 at 3:49 PM
Amoxicillin crystalluria during endocarditis treatment
doi.org/10.1016/j.kint.2024.07.029
#KINephrologyImage #MedSky #NephSky #nephrotoxicity
doi.org/10.1016/j.kint.2024.07.029
#KINephrologyImage #MedSky #NephSky #nephrotoxicity
#RenalPath: CNI nephrotoxicity with TMA involving an arteriole (Jones silver stain).
bit.ly/2qeBWhV (FREE)
bit.ly/2qeBWhV (FREE)
June 22, 2025 at 10:01 AM
#RenalPath: CNI nephrotoxicity with TMA involving an arteriole (Jones silver stain).
bit.ly/2qeBWhV (FREE)
bit.ly/2qeBWhV (FREE)
CASE REPORT
Is Amanita phalloides Nephrotoxicity due to Mitochondrial Toxicity?
https://buff.ly/41U7ZoQ
Is Amanita phalloides Nephrotoxicity due to Mitochondrial Toxicity?
https://buff.ly/41U7ZoQ
January 5, 2025 at 7:14 PM
CASE REPORT
Is Amanita phalloides Nephrotoxicity due to Mitochondrial Toxicity?
https://buff.ly/41U7ZoQ
Is Amanita phalloides Nephrotoxicity due to Mitochondrial Toxicity?
https://buff.ly/41U7ZoQ
Vancomycin and piperacillin tazobactam friends or foes?!
Pseudo or true nephrotoxicity?
#idsky
www.nephjc.com/news/pip-taz...
Pseudo or true nephrotoxicity?
#idsky
www.nephjc.com/news/pip-taz...
November 18, 2024 at 3:49 AM
Vancomycin and piperacillin tazobactam friends or foes?!
Pseudo or true nephrotoxicity?
#idsky
www.nephjc.com/news/pip-taz...
Pseudo or true nephrotoxicity?
#idsky
www.nephjc.com/news/pip-taz...
SNAP trial results reported
Cefazolin was the champion for MSSA
🏆 Less nephrotoxicity than flucoxacillin
🏆 Reduced early mortality
Not published but I think the answer is clear:
Cefazolin now generally 1st line tx for MSSA
"Innoculum effect" with nafcillin= debunked
Updated IBCC (#1/2) #EMIMCC
Cefazolin was the champion for MSSA
🏆 Less nephrotoxicity than flucoxacillin
🏆 Reduced early mortality
Not published but I think the answer is clear:
Cefazolin now generally 1st line tx for MSSA
"Innoculum effect" with nafcillin= debunked
Updated IBCC (#1/2) #EMIMCC
April 12, 2025 at 4:43 PM
SNAP trial results reported
Cefazolin was the champion for MSSA
🏆 Less nephrotoxicity than flucoxacillin
🏆 Reduced early mortality
Not published but I think the answer is clear:
Cefazolin now generally 1st line tx for MSSA
"Innoculum effect" with nafcillin= debunked
Updated IBCC (#1/2) #EMIMCC
Cefazolin was the champion for MSSA
🏆 Less nephrotoxicity than flucoxacillin
🏆 Reduced early mortality
Not published but I think the answer is clear:
Cefazolin now generally 1st line tx for MSSA
"Innoculum effect" with nafcillin= debunked
Updated IBCC (#1/2) #EMIMCC
Approach to immune checkpoint inhibitor (ICI) nephrotoxicity and rechallenge
#ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵
#Onconephrology 🦀 #Nephpearls #NephSky
👉 pubmed.ncbi.nlm.nih.gov/32775813/
#ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵
#Onconephrology 🦀 #Nephpearls #NephSky
👉 pubmed.ncbi.nlm.nih.gov/32775813/
March 28, 2026 at 5:31 AM
Approach to immune checkpoint inhibitor (ICI) nephrotoxicity and rechallenge
#ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵
#Onconephrology 🦀 #Nephpearls #NephSky
👉 pubmed.ncbi.nlm.nih.gov/32775813/
#ISNWCN 🇯🇵 #WCN26 🇯🇵 #WCN2026 🇯🇵
#Onconephrology 🦀 #Nephpearls #NephSky
👉 pubmed.ncbi.nlm.nih.gov/32775813/
Glyphosate: Hepatotoxicity, Nephrotoxicity, Hemotoxicity, Carcinogenicity, and Clinical Cases of Endocrine, Reproductive, Cardiovascular, and Pulmonary System Intoxication | ACS Pharmacology & Translational Science
#Glyphosate = #Homicide & #Ecocide => #MassExtinction
t.co/B0Py2IPvu3
#Glyphosate = #Homicide & #Ecocide => #MassExtinction
t.co/B0Py2IPvu3
May 18, 2026 at 11:26 AM
Glyphosate: Hepatotoxicity, Nephrotoxicity, Hemotoxicity, Carcinogenicity, and Clinical Cases of Endocrine, Reproductive, Cardiovascular, and Pulmonary System Intoxication | ACS Pharmacology & Translational Science
#Glyphosate = #Homicide & #Ecocide => #MassExtinction
t.co/B0Py2IPvu3
#Glyphosate = #Homicide & #Ecocide => #MassExtinction
t.co/B0Py2IPvu3
Keep an 👁️ on PAENIMICIN
Novel 11-residue depsi-lipopeptide found in synthetic-bioinformatic screen of Paenibacillaceae
Binds phosphate and hydroxyl groups on lipid A in Gram- bacteria and teichoic acids in Gram+ bacteria → broad spectrum activity
in vivo efficacy, favorable PK, no nephrotoxicity
Novel 11-residue depsi-lipopeptide found in synthetic-bioinformatic screen of Paenibacillaceae
Binds phosphate and hydroxyl groups on lipid A in Gram- bacteria and teichoic acids in Gram+ bacteria → broad spectrum activity
in vivo efficacy, favorable PK, no nephrotoxicity
A broad-spectrum antibiotic targets multiple-drug-resistant bacteria with dual binding targets and no detectable resistance - Nature Communications
Through a synthetic-bioinformatic natural product approach combined with peptide optimization, a nature inspired antibiotic, paenimicin, was identified from Paenibacillaceae family. Paenimicin feature...
www.nature.com
August 1, 2025 at 4:41 AM
Keep an 👁️ on PAENIMICIN
Novel 11-residue depsi-lipopeptide found in synthetic-bioinformatic screen of Paenibacillaceae
Binds phosphate and hydroxyl groups on lipid A in Gram- bacteria and teichoic acids in Gram+ bacteria → broad spectrum activity
in vivo efficacy, favorable PK, no nephrotoxicity
Novel 11-residue depsi-lipopeptide found in synthetic-bioinformatic screen of Paenibacillaceae
Binds phosphate and hydroxyl groups on lipid A in Gram- bacteria and teichoic acids in Gram+ bacteria → broad spectrum activity
in vivo efficacy, favorable PK, no nephrotoxicity
gotta love nephrotoxicity 🫠
March 4, 2026 at 5:06 PM
gotta love nephrotoxicity 🫠
Correlation between dietary salt intake and renal outcomes related to calcineurin inhibitor nephrotoxicity in kidney transplant recipients
#nephsky
www.nature.com/articles/s41...
#nephsky
www.nature.com/articles/s41...
Correlation between dietary salt intake and renal outcomes related to calcineurin inhibitor nephrotoxicity in kidney transplant recipients - Scientific Reports
Scientific Reports - Correlation between dietary salt intake and renal outcomes related to calcineurin inhibitor nephrotoxicity in kidney transplant recipients
www.nature.com
July 22, 2025 at 2:47 AM
Correlation between dietary salt intake and renal outcomes related to calcineurin inhibitor nephrotoxicity in kidney transplant recipients
#nephsky
www.nature.com/articles/s41...
#nephsky
www.nature.com/articles/s41...
In a CKD pt, the fear of giving iv contrast during a CT (to diagnose cancer) is more than the fear of cancer.
I need radiologists/techs to understand that
A. If I’ve signed the form, I know what I’m doing!
B. The risk of “contrast nephrotoxicity” is negligible, perhaps non-existent.
Read the lit!
I need radiologists/techs to understand that
A. If I’ve signed the form, I know what I’m doing!
B. The risk of “contrast nephrotoxicity” is negligible, perhaps non-existent.
Read the lit!
October 24, 2025 at 2:18 AM
In a CKD pt, the fear of giving iv contrast during a CT (to diagnose cancer) is more than the fear of cancer.
I need radiologists/techs to understand that
A. If I’ve signed the form, I know what I’m doing!
B. The risk of “contrast nephrotoxicity” is negligible, perhaps non-existent.
Read the lit!
I need radiologists/techs to understand that
A. If I’ve signed the form, I know what I’m doing!
B. The risk of “contrast nephrotoxicity” is negligible, perhaps non-existent.
Read the lit!
Symptoms start 24-72 hours after ingestion with headache, vomiting, abdominal pain, flank pain, and then, days to weeks later, oliguric renal failure.
(For you kidney nerds out there, the specific nephrotoxicity is interstitial nephritis with tubular damage and fibrosis of tubules )
(For you kidney nerds out there, the specific nephrotoxicity is interstitial nephritis with tubular damage and fibrosis of tubules )
November 25, 2024 at 10:33 PM
Symptoms start 24-72 hours after ingestion with headache, vomiting, abdominal pain, flank pain, and then, days to weeks later, oliguric renal failure.
(For you kidney nerds out there, the specific nephrotoxicity is interstitial nephritis with tubular damage and fibrosis of tubules )
(For you kidney nerds out there, the specific nephrotoxicity is interstitial nephritis with tubular damage and fibrosis of tubules )
Glyphosate: Hepatotoxicity, Nephrotoxicity, Hemotoxicity, Carcinogenicity, and Clinical Cases of Endocrine, Reproductive, Cardiovascular, and Pulmonary System Intoxication | ACS Pharmacology & Translational Science
#Glyphosate = #Homicide & #Ecocide => #MassExtinction
t.co/B0Py2IPvu3
#Glyphosate = #Homicide & #Ecocide => #MassExtinction
t.co/B0Py2IPvu3
May 18, 2025 at 7:08 AM
Glyphosate: Hepatotoxicity, Nephrotoxicity, Hemotoxicity, Carcinogenicity, and Clinical Cases of Endocrine, Reproductive, Cardiovascular, and Pulmonary System Intoxication | ACS Pharmacology & Translational Science
#Glyphosate = #Homicide & #Ecocide => #MassExtinction
t.co/B0Py2IPvu3
#Glyphosate = #Homicide & #Ecocide => #MassExtinction
t.co/B0Py2IPvu3
thoughts about using linezolid for empiric CNS coverage to avoid nephrotoxicity from vancomycin?
In situations where an LP isn’t immediately feasible, the combination of empiric vancomycin plus acyclovir can be rough on the kidneys.
In situations where an LP isn’t immediately feasible, the combination of empiric vancomycin plus acyclovir can be rough on the kidneys.
#idsky #neurosky #idcrit
#MRSA/#MRSE CNS infection not responding to IV #Vancomycin, follow @idsainfo.bsky.social ‘17 guidelines & begin intrathecal/intraventricular vanc, or switch to #linezolid?
@bradspellberg.bsky.social @mbrigmon.bsky.social @pulmcrit.bsky.social @idvilchez.bsky.social
#MRSA/#MRSE CNS infection not responding to IV #Vancomycin, follow @idsainfo.bsky.social ‘17 guidelines & begin intrathecal/intraventricular vanc, or switch to #linezolid?
@bradspellberg.bsky.social @mbrigmon.bsky.social @pulmcrit.bsky.social @idvilchez.bsky.social
October 15, 2025 at 8:58 PM
thoughts about using linezolid for empiric CNS coverage to avoid nephrotoxicity from vancomycin?
In situations where an LP isn’t immediately feasible, the combination of empiric vancomycin plus acyclovir can be rough on the kidneys.
In situations where an LP isn’t immediately feasible, the combination of empiric vancomycin plus acyclovir can be rough on the kidneys.
#SGLT2 Inhibitors Potential Benefit in #Cisplatin-Associated #Nephrotoxicity Among Diabetic Cancer Patients
#VisualAbstract by @RafaelLpezMrqu2
https://www.kireports.org/article/S2468-0249(26)02770-1/fulltext
#VisualAbstract by @RafaelLpezMrqu2
https://www.kireports.org/article/S2468-0249(26)02770-1/fulltext
May 5, 2026 at 11:00 PM
#SGLT2 Inhibitors Potential Benefit in #Cisplatin-Associated #Nephrotoxicity Among Diabetic Cancer Patients
#VisualAbstract by @RafaelLpezMrqu2
https://www.kireports.org/article/S2468-0249(26)02770-1/fulltext
#VisualAbstract by @RafaelLpezMrqu2
https://www.kireports.org/article/S2468-0249(26)02770-1/fulltext
✅ Lower nephrotoxicity versus colistin-containing regimens.
✅ Improved microbiological eradication of carbapenem-resistant Gram-negative bacilli
✅ Improved microbiological eradication of carbapenem-resistant Gram-negative bacilli
June 2, 2026 at 11:15 AM
✅ Lower nephrotoxicity versus colistin-containing regimens.
✅ Improved microbiological eradication of carbapenem-resistant Gram-negative bacilli
✅ Improved microbiological eradication of carbapenem-resistant Gram-negative bacilli
And the full rounds are available here
www.youtube.com/watch?v=_iXs...
Excellent, thorough overview of all sorts of strange and wonderful nephrotoxicity one can expect to see
@aisha-shaikh.bsky.social #NephGR #OncoNeph
www.youtube.com/watch?v=_iXs...
Excellent, thorough overview of all sorts of strange and wonderful nephrotoxicity one can expect to see
@aisha-shaikh.bsky.social #NephGR #OncoNeph
September 17, 2025 at 4:51 PM
And the full rounds are available here
www.youtube.com/watch?v=_iXs...
Excellent, thorough overview of all sorts of strange and wonderful nephrotoxicity one can expect to see
@aisha-shaikh.bsky.social #NephGR #OncoNeph
www.youtube.com/watch?v=_iXs...
Excellent, thorough overview of all sorts of strange and wonderful nephrotoxicity one can expect to see
@aisha-shaikh.bsky.social #NephGR #OncoNeph
Uzbekistan children die from acute renal failure after consuming cough syrup prepared with diethylene glycol. DEG is the same toxic solvent used in a 1937 antibiotic preparation that led to the 1938 Federal Food, Drug, and Cosmetic Act, creating the modern FDA.
www.kidneynews.org/view/journal...
www.kidneynews.org/view/journal...
February 5, 2024 at 9:21 PM
Uzbekistan children die from acute renal failure after consuming cough syrup prepared with diethylene glycol. DEG is the same toxic solvent used in a 1937 antibiotic preparation that led to the 1938 Federal Food, Drug, and Cosmetic Act, creating the modern FDA.
www.kidneynews.org/view/journal...
www.kidneynews.org/view/journal...
🔬 Maximilian Brol's #POSTER FRI-493
👉 Conversion from standard-release to prolonged-release tacrolimus mitigates #calcineurin-induced #nephrotoxicity in patients after #LiverTransplantation
The poster is still up until 17:00 today ☺️
📅 Presented at #EASLCongress 2025
@medblab.bsky.social
👉 Conversion from standard-release to prolonged-release tacrolimus mitigates #calcineurin-induced #nephrotoxicity in patients after #LiverTransplantation
The poster is still up until 17:00 today ☺️
📅 Presented at #EASLCongress 2025
@medblab.bsky.social
May 9, 2025 at 12:30 PM
🔬 Maximilian Brol's #POSTER FRI-493
👉 Conversion from standard-release to prolonged-release tacrolimus mitigates #calcineurin-induced #nephrotoxicity in patients after #LiverTransplantation
The poster is still up until 17:00 today ☺️
📅 Presented at #EASLCongress 2025
@medblab.bsky.social
👉 Conversion from standard-release to prolonged-release tacrolimus mitigates #calcineurin-induced #nephrotoxicity in patients after #LiverTransplantation
The poster is still up until 17:00 today ☺️
📅 Presented at #EASLCongress 2025
@medblab.bsky.social
Our last work about proteinuria in CAR-T cell therapy. #nephjc #nephsky
academic.oup.com/ckj/advance-...
academic.oup.com/ckj/advance-...
Prospective evaluation of CAR-T cell therapy-related proteinuria and kidney dysfunction
AbstractBackground. The nephrotoxicity of chimeric antigen receptor T-cell (CAR-T) therapy has been reported, yet data on urinary abnormalities remain limi
academic.oup.com
August 28, 2025 at 5:38 PM
Our last work about proteinuria in CAR-T cell therapy. #nephjc #nephsky
academic.oup.com/ckj/advance-...
academic.oup.com/ckj/advance-...
NSAIDs also have a black box warning about increased risk of heart attacks and strokes, so with high doses or greater frequency than labeled, those risks increase as well. I've done med history interviews with pts who presented with GI bleeds and nephrotoxicity d/t high NSAID dosing and frequency.
September 29, 2026 at 6:48 PM
NSAIDs also have a black box warning about increased risk of heart attacks and strokes, so with high doses or greater frequency than labeled, those risks increase as well. I've done med history interviews with pts who presented with GI bleeds and nephrotoxicity d/t high NSAID dosing and frequency.
📖 This weekend don't miss our @kidneyint.bsky.social #ISNFridaySelection: Pathological findings of immunotherapy-induced nephrotoxicity in a humanized immune system mouse model www.kidney-internati...
May 16, 2025 at 6:00 AM
📖 This weekend don't miss our @kidneyint.bsky.social #ISNFridaySelection: Pathological findings of immunotherapy-induced nephrotoxicity in a humanized immune system mouse model www.kidney-internati...
Dose AG appropriately and for short duration and you will not run into either ototoxicity or nephrotoxicity (cases of clear cut oto/nephro I have encountered have been in the setting of endocarditis)
July 25, 2025 at 6:10 PM
Dose AG appropriately and for short duration and you will not run into either ototoxicity or nephrotoxicity (cases of clear cut oto/nephro I have encountered have been in the setting of endocarditis)
