Then there's PEM.
The researchers report that PEM and fatigue were common across all five subtypes.
It doesn't state the methods to determine PEM. BUT if it's the previous one RECOVER ENERGISE used it's REALLY broad. /9
The researchers report that PEM and fatigue were common across all five subtypes.
It doesn't state the methods to determine PEM. BUT if it's the previous one RECOVER ENERGISE used it's REALLY broad. /9
November 3, 2026 at 7:07 PM
Then there's PEM.
The researchers report that PEM and fatigue were common across all five subtypes.
It doesn't state the methods to determine PEM. BUT if it's the previous one RECOVER ENERGISE used it's REALLY broad. /9
The researchers report that PEM and fatigue were common across all five subtypes.
It doesn't state the methods to determine PEM. BUT if it's the previous one RECOVER ENERGISE used it's REALLY broad. /9
November 4, 2026 at 8:16 PM
Did they have the information to correctly identify PEM?
Would the analysis have looked different if they had separated a PEM and a non-PEM subgroup??
#LongCovid
#ME
Would the analysis have looked different if they had separated a PEM and a non-PEM subgroup??
#LongCovid
#ME
November 3, 2026 at 6:35 AM
Did they have the information to correctly identify PEM?
Would the analysis have looked different if they had separated a PEM and a non-PEM subgroup??
#LongCovid
#ME
Would the analysis have looked different if they had separated a PEM and a non-PEM subgroup??
#LongCovid
#ME
We need to know reliably the proportion of those with Long Covid who have PEM - as PEM is the defining characteristic of ME.
Do most people with Long Covid have ME? Or are we conflating fatigue?
This is a huge problem in ME & now LC. We need better assessment. /10
Do most people with Long Covid have ME? Or are we conflating fatigue?
This is a huge problem in ME & now LC. We need better assessment. /10
November 3, 2026 at 7:07 PM
We need to know reliably the proportion of those with Long Covid who have PEM - as PEM is the defining characteristic of ME.
Do most people with Long Covid have ME? Or are we conflating fatigue?
This is a huge problem in ME & now LC. We need better assessment. /10
Do most people with Long Covid have ME? Or are we conflating fatigue?
This is a huge problem in ME & now LC. We need better assessment. /10
Open Medicine Foundation - OMF: "Dr. Dan Peterson on ME/CFS: Origins, PEM, Biomarkers, and Hope for Better Diagnostics"
www.youtube.com/watch?v=_gnn...
www.youtube.com/watch?v=_gnn...
Dr. Dan Peterson on ME/CFS: Origins, PEM, Biomarkers, and Hope for Better Diagnostics
YouTube video by Open Medicine Foundation - OMF
www.youtube.com
November 3, 2026 at 5:18 PM
Open Medicine Foundation - OMF: "Dr. Dan Peterson on ME/CFS: Origins, PEM, Biomarkers, and Hope for Better Diagnostics"
www.youtube.com/watch?v=_gnn...
www.youtube.com/watch?v=_gnn...
❤️🩹 PEM is kicking my arse x
please support me, a disabled queer crafter so i can pay my bills for november. it’s already a tight month. taxes are expensive to get done. i can’t work except my crafts and my blog sort of. i worked until i was too sick to keep going.
anything helps!
madewithsash.etsy.com
ko-fi.com/isthisrunning
anything helps!
madewithsash.etsy.com
ko-fi.com/isthisrunning
November 2, 2026 at 4:24 PM
❤️🩹 PEM is kicking my arse x
So sorry you're going through this and I really hope you are aware that repeated PEM tends to lower your baseline!
This is a huge issue where officialdom will not give accurate warnings about risk. It is always positioned that *some* people *may* experience *fluctuation*.
In reality 67% of #pwME have experienced a PEM crash they never recovered from and many of us are severe from bad or late advice.
In reality 67% of #pwME have experienced a PEM crash they never recovered from and many of us are severe from bad or late advice.
November 3, 2026 at 11:18 AM
So sorry you're going through this and I really hope you are aware that repeated PEM tends to lower your baseline!
A better understanding of the pathophysiology of #PEM in #ME/CFS could lead to therapeutic advances in this common and debilitating condition for which no specific treatment is currently available. mTORC1 may act as a transition switch when energy stress should promote autophagy, mitophagy, and
mTORC1 dysregulation and context-dependent mitochondrial dysfunction in ME/CFS: a mechanistic and translational review - Journal of Translational Medicine
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a common, debilitating, multisystemic disease whose cardinal symptom is post-exertional malaise (PEM). PEM is a delayed and sustained exa...
link.springer.com
November 2, 2026 at 1:03 PM
November 4, 2026 at 1:45 PM
De vreetzin slaat genadeloos toe, dus het einde van de migraine/pem is in zicht. Wonderlijk toch, hoe onze lijven werken 🤷🏻♀️
November 3, 2026 at 2:48 PM
De vreetzin slaat genadeloos toe, dus het einde van de migraine/pem is in zicht. Wonderlijk toch, hoe onze lijven werken 🤷🏻♀️
Am 12.11., 19–20:30 Uhr,
ist
@karin-kelle-herfurth.de
zu Gast im Psychotherapie-Netzwerk ME/CFS:
„Wenn Genesungsgeschichten bei ME/CFS zum Maßstab werden“
Vortrag und Diskussion für psychotherapeutische Kolleg:innen.
#MECFS #PEM
Anmeldungen unter:
www.psychotherapie-mecfs.de/termine/
ist
@karin-kelle-herfurth.de
zu Gast im Psychotherapie-Netzwerk ME/CFS:
„Wenn Genesungsgeschichten bei ME/CFS zum Maßstab werden“
Vortrag und Diskussion für psychotherapeutische Kolleg:innen.
#MECFS #PEM
Anmeldungen unter:
www.psychotherapie-mecfs.de/termine/
Termine
www.psychotherapie-mecfs.de
November 3, 2026 at 9:34 AM
Am 12.11., 19–20:30 Uhr,
ist
@karin-kelle-herfurth.de
zu Gast im Psychotherapie-Netzwerk ME/CFS:
„Wenn Genesungsgeschichten bei ME/CFS zum Maßstab werden“
Vortrag und Diskussion für psychotherapeutische Kolleg:innen.
#MECFS #PEM
Anmeldungen unter:
www.psychotherapie-mecfs.de/termine/
ist
@karin-kelle-herfurth.de
zu Gast im Psychotherapie-Netzwerk ME/CFS:
„Wenn Genesungsgeschichten bei ME/CFS zum Maßstab werden“
Vortrag und Diskussion für psychotherapeutische Kolleg:innen.
#MECFS #PEM
Anmeldungen unter:
www.psychotherapie-mecfs.de/termine/
The other crucial issue: pacing.
Someone with PEM may experience fewer crashes b/c they've drastically reduced their activity, not b/c their illness has improved.
Without assessing activity and functional capacity, how do we distinguish symptom management from recovery? /11
Someone with PEM may experience fewer crashes b/c they've drastically reduced their activity, not b/c their illness has improved.
Without assessing activity and functional capacity, how do we distinguish symptom management from recovery? /11
November 3, 2026 at 7:07 PM
The other crucial issue: pacing.
Someone with PEM may experience fewer crashes b/c they've drastically reduced their activity, not b/c their illness has improved.
Without assessing activity and functional capacity, how do we distinguish symptom management from recovery? /11
Someone with PEM may experience fewer crashes b/c they've drastically reduced their activity, not b/c their illness has improved.
Without assessing activity and functional capacity, how do we distinguish symptom management from recovery? /11
Wenn dann eine solche Studie einschlägt, wird man das gleiche machen müssen, wie bei allen Post Covid-Studien - sich das eingeschlossene Kollekt sehr genau anschauen.
Wie schwer betroffen? PEM vorhanden? Welcher klinische Phänotyp?
Wie schwer betroffen? PEM vorhanden? Welcher klinische Phänotyp?
October 31, 2026 at 2:35 PM
Wenn dann eine solche Studie einschlägt, wird man das gleiche machen müssen, wie bei allen Post Covid-Studien - sich das eingeschlossene Kollekt sehr genau anschauen.
Wie schwer betroffen? PEM vorhanden? Welcher klinische Phänotyp?
Wie schwer betroffen? PEM vorhanden? Welcher klinische Phänotyp?
まずい
ここに来て、あり得ないと思うのだけど、PEMに襲われている。歩けないぞ……
ここに来て、あり得ないと思うのだけど、PEMに襲われている。歩けないぞ……
November 2, 2026 at 8:06 AM
まずい
ここに来て、あり得ないと思うのだけど、PEMに襲われている。歩けないぞ……
ここに来て、あり得ないと思うのだけど、PEMに襲われている。歩けないぞ……
昨夜あれほどPEMに苛まれたにもかかわらず、朝7時に外に飛び出し、未だに帰路についていない…昭和脳筋に付ける薬などない。
November 2, 2026 at 11:49 PM
昨夜あれほどPEMに苛まれたにもかかわらず、朝7時に外に飛び出し、未だに帰路についていない…昭和脳筋に付ける薬などない。
Thank you PEM for the reply.
November 2, 2026 at 6:26 PM
Thank you PEM for the reply.
寒暖差や気圧変動がPEMのタイムラグに影響を及ぼす…なるほどそうかもしれぬ…何もできないので何もしていない…
November 2, 2026 at 10:49 AM
寒暖差や気圧変動がPEMのタイムラグに影響を及ぼす…なるほどそうかもしれぬ…何もできないので何もしていない…
Hospital. Resting at “home” now. Wrecked. Waiting for PEM to hit. 🥺
It’s cold here. No heating. 🥶
It’s cold here. No heating. 🥶
November 4, 2026 at 9:09 PM
Hospital. Resting at “home” now. Wrecked. Waiting for PEM to hit. 🥺
It’s cold here. No heating. 🥶
It’s cold here. No heating. 🥶
Celebrating some bright blue skies today, friends. Hope you're having a blue wave night ✨️💙✨️
Some pics from my day with the Dharma and Pem(a). Good night!
Some pics from my day with the Dharma and Pem(a). Good night!
November 5, 2026 at 2:04 AM
Celebrating some bright blue skies today, friends. Hope you're having a blue wave night ✨️💙✨️
Some pics from my day with the Dharma and Pem(a). Good night!
Some pics from my day with the Dharma and Pem(a). Good night!
no wonder my body feels horrendous this is mimicking PEM for me!!!!
November 4, 2026 at 8:40 PM
no wonder my body feels horrendous this is mimicking PEM for me!!!!
I want to dedicate this to PEM, wish you the best even in times like this. I hold no grudges and hate no 1 except DJT.
www.youtube.com/watch?v=gkKO...
www.youtube.com/watch?v=gkKO...
Under the Bridge
YouTube video by Red Hot Chili Peppers - Topic
www.youtube.com
November 3, 2026 at 5:57 PM
I want to dedicate this to PEM, wish you the best even in times like this. I hold no grudges and hate no 1 except DJT.
www.youtube.com/watch?v=gkKO...
www.youtube.com/watch?v=gkKO...
Psykologer som har kunnskap om ME og PEM kan være til stor støtte for ME-syke som får livet snudd opp-ned. Dessverre er kompetansen ofte lav.
Derfor trenger vi en kompetansehevende retningslinje for ME/CFS.
Derfor trenger vi en kompetansehevende retningslinje for ME/CFS.
November 1, 2026 at 1:56 PM
Psykologer som har kunnskap om ME og PEM kan være til stor støtte for ME-syke som får livet snudd opp-ned. Dessverre er kompetansen ofte lav.
Derfor trenger vi en kompetansehevende retningslinje for ME/CFS.
Derfor trenger vi en kompetansehevende retningslinje for ME/CFS.
En hoezo is het al weer bijna twee uur???
*nog een poging doet om uit bed te komen*
Stomme PEM.
*nog een poging doet om uit bed te komen*
Stomme PEM.
November 1, 2026 at 12:29 PM
En hoezo is het al weer bijna twee uur???
*nog een poging doet om uit bed te komen*
Stomme PEM.
*nog een poging doet om uit bed te komen*
Stomme PEM.
Moments later, she was licked.
Moments later, there was combat.
I love it! Thank you Pem!! 💕💕
Moments later, there was combat.
I love it! Thank you Pem!! 💕💕
November 1, 2026 at 6:04 PM
Moments later, she was licked.
Moments later, there was combat.
I love it! Thank you Pem!! 💕💕
Moments later, there was combat.
I love it! Thank you Pem!! 💕💕