Who wants a nice cold glass of human polyomavirus vaccine lager?
This cancer researcher home-brewed a beer that works as a vaccine
And he's publishing the process so you can do it too.
reason.com
March 16, 2026 at 7:39 PM
Who wants a nice cold glass of human polyomavirus vaccine lager?
I’m excited to share the first publication from my lab on the unexpected strategy that MCPyV, a cancer-causing virus, uses to enter cells. This was truly a team effort and I am so grateful for each of the brilliant women who contributed to this research project. journals.plos.org/plospathogen...
Temporal gating of nuclear import: How Merkel cell polyomavirus exploits the cell cycle for nuclear entry
Author summary Merkel cell polyomavirus (MCPyV) causes a rare but deadly form of skin cancer called Merkel cell carcinoma. However, many aspects of its infectious life cycle are unclear, including how...
journals.plos.org
June 19, 2025 at 4:05 PM
I’m excited to share the first publication from my lab on the unexpected strategy that MCPyV, a cancer-causing virus, uses to enter cells. This was truly a team effort and I am so grateful for each of the brilliant women who contributed to this research project. journals.plos.org/plospathogen...
Taxonomy Time Machine now shows merges taxonomy.onecodex.com
May 14, 2026 at 10:31 PM
Taxonomy Time Machine now shows merges taxonomy.onecodex.com
"A highly potent human antibody neutralizing all serotypes of BK polyomavirus"
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
A highly potent human antibody neutralizing all serotypes of BK polyomavirus
Author summary BK polyomavirus (BKPyV) is a common virus that infects most people during childhood and typically remains dormant in the kidneys without causing harm. However, in kidney transplant pati...
journals.plos.org
July 19, 2025 at 11:13 AM
"A highly potent human antibody neutralizing all serotypes of BK polyomavirus"
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
The @who.int cancer agency just added cytomegalovirus (HCMV) and hepatitis D virus (HDV) to the growing list of viruses officially linked to cancer. That brings the number of known cancer-associated viruses to 10.
www.iarc.who.int/news-events/...
www.iarc.who.int/news-events/...
<em>IARC Monographs</em> evaluation of the carcinogenicity of hepatitis D virus, human cytomegalovirus, and Merkel cell polyomavirus
www.iarc.who.int
July 14, 2025 at 8:48 PM
The @who.int cancer agency just added cytomegalovirus (HCMV) and hepatitis D virus (HDV) to the growing list of viruses officially linked to cancer. That brings the number of known cancer-associated viruses to 10.
www.iarc.who.int/news-events/...
www.iarc.who.int/news-events/...
Alarming Findings on JC Polyomavirus Virus Spread and Fatal Brain Risks
www.thailandmedical.news/news/alarmin...
www.thailandmedical.news/news/alarmin...
Alarming Findings on JC Polyomavirus Virus Spread and Fatal Brain Risks - Thailand Medical News
www.thailandmedical.news
June 30, 2026 at 6:22 AM
Alarming Findings on JC Polyomavirus Virus Spread and Fatal Brain Risks
www.thailandmedical.news/news/alarmin...
www.thailandmedical.news/news/alarmin...
Striking viral inclusion in this case of polyomavirus nephropathy. SV40 stain is confirmatory. #renalpath #pathsky #nephsky
May 4, 2026 at 5:24 PM
Striking viral inclusion in this case of polyomavirus nephropathy. SV40 stain is confirmatory. #renalpath #pathsky #nephsky
These viruses are now linked to human cancers:
Epstein–Barr virus
Hepatitis B virus
Hepatitis C virus
Human immunodeficiency virus
Kaposi sarcoma–associated herpesvirus
Human papillomavirus
Merkel cell polyomavirus
Human T-cell leukemia virus type 1
Hepatitis D virus
Human cytomegalovirus
Epstein–Barr virus
Hepatitis B virus
Hepatitis C virus
Human immunodeficiency virus
Kaposi sarcoma–associated herpesvirus
Human papillomavirus
Merkel cell polyomavirus
Human T-cell leukemia virus type 1
Hepatitis D virus
Human cytomegalovirus
July 14, 2025 at 8:48 PM
These viruses are now linked to human cancers:
Epstein–Barr virus
Hepatitis B virus
Hepatitis C virus
Human immunodeficiency virus
Kaposi sarcoma–associated herpesvirus
Human papillomavirus
Merkel cell polyomavirus
Human T-cell leukemia virus type 1
Hepatitis D virus
Human cytomegalovirus
Epstein–Barr virus
Hepatitis B virus
Hepatitis C virus
Human immunodeficiency virus
Kaposi sarcoma–associated herpesvirus
Human papillomavirus
Merkel cell polyomavirus
Human T-cell leukemia virus type 1
Hepatitis D virus
Human cytomegalovirus
You‘re welcome.
Bobby doesn’t know how to read a study.
“the Inst of Medicine found that the epidemiological data for cancer rates in people potentially exposed to SV40-contaminated vaccines are inadequate to evaluate a causal relationship…”
pmc.ncbi.nlm.nih.gov/articles/PMC...
under his auspices…
Bobby doesn’t know how to read a study.
“the Inst of Medicine found that the epidemiological data for cancer rates in people potentially exposed to SV40-contaminated vaccines are inadequate to evaluate a causal relationship…”
pmc.ncbi.nlm.nih.gov/articles/PMC...
under his auspices…
Emergent Human Pathogen Simian Virus 40 and Its Role in Cancer
The polyomavirus simian virus 40 (SV40) is a known oncogenic DNA virus which induces primary brain and bone cancers, malignant mesothelioma, and lymphomas in laboratory animals. Persuasive evidence no...
pmc.ncbi.nlm.nih.gov
August 18, 2026 at 3:21 AM
You‘re welcome.
Bobby doesn’t know how to read a study.
“the Inst of Medicine found that the epidemiological data for cancer rates in people potentially exposed to SV40-contaminated vaccines are inadequate to evaluate a causal relationship…”
pmc.ncbi.nlm.nih.gov/articles/PMC...
under his auspices…
Bobby doesn’t know how to read a study.
“the Inst of Medicine found that the epidemiological data for cancer rates in people potentially exposed to SV40-contaminated vaccines are inadequate to evaluate a causal relationship…”
pmc.ncbi.nlm.nih.gov/articles/PMC...
under his auspices…
Remy Yeast will soon be selling bioengineered yeast (dry & beer) that produces viral shell proteins! First up: BK polyomavirus genotype-I VP1 & BK polyomavirus genotype-IV VP1. Sign up for their email list if you're interested => remyeast.com
More on my Substack: moreisdifferent.blog/p/yeast-base...
More on my Substack: moreisdifferent.blog/p/yeast-base...
May 1, 2026 at 7:55 PM
Remy Yeast will soon be selling bioengineered yeast (dry & beer) that produces viral shell proteins! First up: BK polyomavirus genotype-I VP1 & BK polyomavirus genotype-IV VP1. Sign up for their email list if you're interested => remyeast.com
More on my Substack: moreisdifferent.blog/p/yeast-base...
More on my Substack: moreisdifferent.blog/p/yeast-base...
Exited to share our recent work on viral cis-regulatory elements in collaboration with @tewhey.bsky.social!
We identified >2000 CREs across the genomes of 27 human-infecting dsDNA viruses from the Herpesvirus, Adenovirus, Papillomavirus, and Polyomavirus families.
www.biorxiv.org/content/10.1...
1/8
We identified >2000 CREs across the genomes of 27 human-infecting dsDNA viruses from the Herpesvirus, Adenovirus, Papillomavirus, and Polyomavirus families.
www.biorxiv.org/content/10.1...
1/8
July 24, 2025 at 7:18 PM
Exited to share our recent work on viral cis-regulatory elements in collaboration with @tewhey.bsky.social!
We identified >2000 CREs across the genomes of 27 human-infecting dsDNA viruses from the Herpesvirus, Adenovirus, Papillomavirus, and Polyomavirus families.
www.biorxiv.org/content/10.1...
1/8
We identified >2000 CREs across the genomes of 27 human-infecting dsDNA viruses from the Herpesvirus, Adenovirus, Papillomavirus, and Polyomavirus families.
www.biorxiv.org/content/10.1...
1/8
BK Polyomavirus-Associated Nephropathy
- BKPyVAN is a significant cause of kidney transplant complications. With no standardized treatment protocols, immunosuppression reduction remains the cornerstone of management. #TransplantNephrology #BKPyVAN
- BKPyVAN is a significant cause of kidney transplant complications. With no standardized treatment protocols, immunosuppression reduction remains the cornerstone of management. #TransplantNephrology #BKPyVAN
January 12, 2025 at 1:11 PM
BK Polyomavirus-Associated Nephropathy
- BKPyVAN is a significant cause of kidney transplant complications. With no standardized treatment protocols, immunosuppression reduction remains the cornerstone of management. #TransplantNephrology #BKPyVAN
- BKPyVAN is a significant cause of kidney transplant complications. With no standardized treatment protocols, immunosuppression reduction remains the cornerstone of management. #TransplantNephrology #BKPyVAN
Trichodysplasia spinulosa–associated polyomavirus was identified as a likely cause of neuroinvasive infection in a 16-year-old patient who had undergone renal transplantation. Full details in a new correspondence: https://nej.md/4cDwOtP
September 16, 2026 at 7:00 PM
Trichodysplasia spinulosa–associated polyomavirus was identified as a likely cause of neuroinvasive infection in a 16-year-old patient who had undergone renal transplantation. Full details in a new correspondence: https://nej.md/4cDwOtP
How long-term persistent virus infection could cause inflammatory-associated cancer in uninfected cells:
Polyomavirus BKPyV
www.science.org/doi/10.1126/...
Polyomavirus BKPyV
www.science.org/doi/10.1126/...
Virus-induced APOBEC3 transmutagenesis in bladder cancer initiation
A model for hit-and-run viral carcinogenesis in the bladder.
www.science.org
December 4, 2025 at 2:32 PM
How long-term persistent virus infection could cause inflammatory-associated cancer in uninfected cells:
Polyomavirus BKPyV
www.science.org/doi/10.1126/...
Polyomavirus BKPyV
www.science.org/doi/10.1126/...
Single-cell analysis reveals host S phase drives large T antigen expression during BK polyomavirus infection
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Single-cell analysis reveals host S phase drives large T antigen expression during BK polyomavirus infection
Author summary BK polyomavirus (BKPyV) is the leading cause of graft loss in kidney transplant patients due to the lack of effective antivirals. Previous studies have implied that early expression of ...
journals.plos.org
December 6, 2024 at 4:05 PM
Single-cell analysis reveals host S phase drives large T antigen expression during BK polyomavirus infection
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
𝗜𝗦𝗡 𝗩𝗜𝗗𝗘𝗢 𝗔𝗕𝗦𝗧𝗥𝗔𝗖𝗧 𝗦𝗘𝗥𝗜𝗘𝗦: Insights from the BKEVER Trial comparing everolimus versus mycophenolate mofetil for BK Polyomavirus infection in kidney transplant recipients www.kidney-internati...
#VideoAbstract by @raphapalma.bsky.social & @acssjr.bsky.social
#VideoAbstract by @raphapalma.bsky.social & @acssjr.bsky.social
April 8, 2025 at 12:00 PM
𝗜𝗦𝗡 𝗩𝗜𝗗𝗘𝗢 𝗔𝗕𝗦𝗧𝗥𝗔𝗖𝗧 𝗦𝗘𝗥𝗜𝗘𝗦: Insights from the BKEVER Trial comparing everolimus versus mycophenolate mofetil for BK Polyomavirus infection in kidney transplant recipients www.kidney-internati...
#VideoAbstract by @raphapalma.bsky.social & @acssjr.bsky.social
#VideoAbstract by @raphapalma.bsky.social & @acssjr.bsky.social
new data on potravitug, a drug for bk polyomavirus-associated nephropathy (bkpyvan). this is a tough kidney complication after transplant, with no approved targeted treatments. in a phase 2 trial, 24.
July 4, 2026 at 2:02 AM
new data on potravitug, a drug for bk polyomavirus-associated nephropathy (bkpyvan). this is a tough kidney complication after transplant, with no approved targeted treatments. in a phase 2 trial, 24.
k is for B. K.'s virus, a polyomavirus. it infects your respiratory system
L is for Legionellosis, found by legionnaires
M is for mycobacterium marinum, which gives you lesions instead
n is for norovirus, often caught on cruises
O is for otitis externa, often obtained by swimming in dirty water
L is for Legionellosis, found by legionnaires
M is for mycobacterium marinum, which gives you lesions instead
n is for norovirus, often caught on cruises
O is for otitis externa, often obtained by swimming in dirty water
December 31, 2024 at 8:50 PM
k is for B. K.'s virus, a polyomavirus. it infects your respiratory system
L is for Legionellosis, found by legionnaires
M is for mycobacterium marinum, which gives you lesions instead
n is for norovirus, often caught on cruises
O is for otitis externa, often obtained by swimming in dirty water
L is for Legionellosis, found by legionnaires
M is for mycobacterium marinum, which gives you lesions instead
n is for norovirus, often caught on cruises
O is for otitis externa, often obtained by swimming in dirty water
More on the newly added viruses on the list in this Lancet review that accompanied the update:
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Carcinogenicity of hepatitis D virus, human cytomegalovirus, and Merkel cell polyomavirus
In June, 2025, 17 scientists from ten countries met at the International Agency for
Research on Cancer (IARC) in Lyon, France, to finalise their evaluation of hepatitis
D virus (HDV), human cytomegalo...
www.thelancet.com
July 14, 2025 at 8:48 PM
More on the newly added viruses on the list in this Lancet review that accompanied the update:
www.thelancet.com/journals/lan...
www.thelancet.com/journals/lan...
Asano, Veatch, and Sung et al. identified TCRMCC1, a high-avidity HLA-A*02:01-restricted TCR targeting Merkel cell polyomavirus large-T antigen and treated seven patients who had ICI-refractory metastatic MCC using autologous TCRMCC1-transduced [...] @fredhutch.org
bit.ly/46BEhGz
bit.ly/46BEhGz
September 29, 2026 at 11:38 AM
Asano, Veatch, and Sung et al. identified TCRMCC1, a high-avidity HLA-A*02:01-restricted TCR targeting Merkel cell polyomavirus large-T antigen and treated seven patients who had ICI-refractory metastatic MCC using autologous TCRMCC1-transduced [...] @fredhutch.org
bit.ly/46BEhGz
bit.ly/46BEhGz
Our 3D printed model of BK polyomavirus from the #AstburyConversation public engagement event! https://t.co/vmraB3DUKM
November 23, 2024 at 12:34 AM
Our 3D printed model of BK polyomavirus from the #AstburyConversation public engagement event! https://t.co/vmraB3DUKM
Merkel cell polyomavirus latently infects most of the human population, and can in some cases lead to skin cancer. Silvia Albertini (university hospital Hamburg) shows how skin organoids, analyzed using single-cell and spatial transcriptomics, can be an infection model for this virus.
March 4, 2025 at 5:13 PM
Merkel cell polyomavirus latently infects most of the human population, and can in some cases lead to skin cancer. Silvia Albertini (university hospital Hamburg) shows how skin organoids, analyzed using single-cell and spatial transcriptomics, can be an infection model for this virus.
About the vaccine.
Designing a Multi-Epitope Subunit Vaccine against VP1 Major Coat Protein of JC Polyomavirus
The JC polyomavirus virus (JCPyV) affects more than 80% of the human population in their early life stage. It mainly affects immunocompromised individuals where virus replication in oligodendrocytes and astrocytes may lead to fatal progressive ...
pmc.ncbi.nlm.nih.gov
March 21, 2026 at 6:58 PM
About the vaccine.