—Reduction of gut inflammation by GIP (gastric inhibitory polypeptide)
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...
December 27, 2024 at 2:55 PM
—Reduction of gut inflammation by GIP (gastric inhibitory polypeptide)
insight.jci.org/articles/vie...
insight.jci.org/articles/vie...
Guten Morgen, ihr Polypeptide.🌞
July 17, 2026 at 4:29 AM
Guten Morgen, ihr Polypeptide.🌞
Unless the newsletter has instructions for milking the venom out of Gila monsters, isolating and purifying the components, and then chemically and structurally modifying polypeptide hormones, then I’d say store bought is just fine
May 9, 2025 at 9:12 PM
Unless the newsletter has instructions for milking the venom out of Gila monsters, isolating and purifying the components, and then chemically and structurally modifying polypeptide hormones, then I’d say store bought is just fine
Congratulations to Shrey Parikh from Rancho Cucamonga, California, for winning the Scripps National Spelling Bee!
Shrey’s winning word was bromocriptine, a polypeptide alkaloid that acts like dopamine. Hopefully, his win had a similar effect on him!
Shrey’s winning word was bromocriptine, a polypeptide alkaloid that acts like dopamine. Hopefully, his win had a similar effect on him!
May 29, 2026 at 5:52 PM
Congratulations to Shrey Parikh from Rancho Cucamonga, California, for winning the Scripps National Spelling Bee!
Shrey’s winning word was bromocriptine, a polypeptide alkaloid that acts like dopamine. Hopefully, his win had a similar effect on him!
Shrey’s winning word was bromocriptine, a polypeptide alkaloid that acts like dopamine. Hopefully, his win had a similar effect on him!
active ingredient but can be used to treat different conditions. Zepbound works by activating receptors of hormones secreted from the intestine (glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)) to reduce appetite and food intake. By reducing body weight,
December 21, 2024 at 5:03 PM
active ingredient but can be used to treat different conditions. Zepbound works by activating receptors of hormones secreted from the intestine (glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)) to reduce appetite and food intake. By reducing body weight,
Now that we've gendered Estrogen and Testosterone as female and male respectively I say we need to gender the other hormones too. Dopamine? Non-binary. Insulin? It's gender fluid, baybee. Gastric Inhibitory Polypeptide? that's right, that's an agender hormone
November 20, 2023 at 5:22 PM
Now that we've gendered Estrogen and Testosterone as female and male respectively I say we need to gender the other hormones too. Dopamine? Non-binary. Insulin? It's gender fluid, baybee. Gastric Inhibitory Polypeptide? that's right, that's an agender hormone
My body is a machine that turns amino acids into polypeptide chains.
September 8, 2025 at 3:57 PM
My body is a machine that turns amino acids into polypeptide chains.
now that we've gendered Estrogen and Testosterone as male and female respectively I say we need to gender the other hormones too. Dopamine? Non-binary. Insulin? It's gender fluid, baybee. Gastric Inhibitory Polypeptide? that's right francis that's an agender hormone
February 13, 2025 at 10:18 AM
now that we've gendered Estrogen and Testosterone as male and female respectively I say we need to gender the other hormones too. Dopamine? Non-binary. Insulin? It's gender fluid, baybee. Gastric Inhibitory Polypeptide? that's right francis that's an agender hormone
Want to know how lipidation of some nascent chains takes place by NMT2-- Check our latest work on how NAC couples Protein Synthesis with Nascent Polypeptide Myristoylation on the Ribosome out today @embojournal.org: www.embopress.org/doi/full/10....
August 26, 2025 at 11:00 AM
Want to know how lipidation of some nascent chains takes place by NMT2-- Check our latest work on how NAC couples Protein Synthesis with Nascent Polypeptide Myristoylation on the Ribosome out today @embojournal.org: www.embopress.org/doi/full/10....
Samsung Biologics to launch takeover bid for PolyPeptide in September reut.rs/45WJ9FO
Samsung Biologics to launch takeover bid for PolyPeptide in September
Samsung Biologics will launch its takeover offer for Swiss contract drugmaker PolyPeptide Group in September, the South Korean company said in an offer prospectus on Monday.
reut.rs
August 31, 2026 at 5:50 AM
Samsung Biologics to launch takeover bid for PolyPeptide in September reut.rs/45WJ9FO
please my polypeptide chains are twisting in anticipation
April 7, 2025 at 7:25 AM
please my polypeptide chains are twisting in anticipation
Samsung Biologics to acquire Switzerland's PolyPeptide Group in $1.8 billion all-cash deal
Samsung Biologics to acquire Switzerland's PolyPeptide Group in $1.8 billion all-cash deal
Samsung Biologics acquires PolyPeptide Group for 2.7 trillion won ($1.8 billion)
cnb.cx
July 20, 2026 at 2:19 AM
Samsung Biologics to acquire Switzerland's PolyPeptide Group in $1.8 billion all-cash deal
By my reckoning, yesterday marked the 50th anniversary of ubiquitin's discovery! 🎈🎉🎁🥂
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells. | PNAS
A polypeptide of 8500 molecular weight is described that induces the differentiation
of T (thymus-derived) cell and B (bone-marrow-derived) cell im...
www.pnas.org
January 16, 2025 at 1:25 PM
By my reckoning, yesterday marked the 50th anniversary of ubiquitin's discovery! 🎈🎉🎁🥂
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Now that we've gendered Estrogen and Testosterone as female and male respectively I say we need to gender the other hormones too. Dopamine? Non-binary. Insulin? It's gender fluid, baybee. Gastric Inhibitory Polypeptide? that's right francis that's an agender hormone
August 10, 2023 at 2:35 PM
Now that we've gendered Estrogen and Testosterone as female and male respectively I say we need to gender the other hormones too. Dopamine? Non-binary. Insulin? It's gender fluid, baybee. Gastric Inhibitory Polypeptide? that's right francis that's an agender hormone
Slightly overdue article highlight!
In PNAS, we use smFRET to reveal how polypeptide release factor 2 (RF2) undergoes a cascade of structural changes to catalyze polypeptide release during translation termination and ArfA-mediated ribosome rescue.
🧵⬇️
doi.org/10.1073/pnas...
In PNAS, we use smFRET to reveal how polypeptide release factor 2 (RF2) undergoes a cascade of structural changes to catalyze polypeptide release during translation termination and ArfA-mediated ribosome rescue.
🧵⬇️
doi.org/10.1073/pnas...
January 5, 2026 at 4:27 PM
Slightly overdue article highlight!
In PNAS, we use smFRET to reveal how polypeptide release factor 2 (RF2) undergoes a cascade of structural changes to catalyze polypeptide release during translation termination and ArfA-mediated ribosome rescue.
🧵⬇️
doi.org/10.1073/pnas...
In PNAS, we use smFRET to reveal how polypeptide release factor 2 (RF2) undergoes a cascade of structural changes to catalyze polypeptide release during translation termination and ArfA-mediated ribosome rescue.
🧵⬇️
doi.org/10.1073/pnas...
Glucose-Dependent Insulinotropic Polypeptide Receptors Are Expressed in the Lateral Septum and Reduce Electrically-Evoked Dopamine Release as well as the Ability of Cocaine to Increase Extracellular Dopamine | ACS Chemical Neuroscience pubs.acs.org/doi/10.1021/...
Glucose-Dependent Insulinotropic Polypeptide Receptors Are Expressed in the Lateral Septum and Reduce Electrically-Evoked Dopamine Release as well as the Ability of Cocaine to Increase Extracellular Dopamine
Tirzepatide, a dual agonist of the glucagon-like peptide 1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR), represents a new class of medication for obesity and type II diabetes treatment. Using laboratory mice, we show that GIPRs are present in the lateral septum (LS) in cells also expressing GLP-1R, particularly in the dorsolateral LS. Likewise, we show the coexpression of the dopamine (DA) D2 receptor (DRD2) in LS cells with GLP-1R in both the dorsolateral and intermediate portions of the LS. Using fast-scan cyclic voltammetry, we demonstrate that systemic GLP-1R or GIPR agonist treatment reduces both electrically evoked DA release in the LS and the ability of cocaine to increase extracellular DA levels. These data unveil a new central role for GIPR signaling and identify a potentially important cell type expressing both GLP-1R and GIPR upon which tirzepatide or other dual agonists may modulate DA homeostasis in the brain.
pubs.acs.org
June 1, 2026 at 9:28 PM
Glucose-Dependent Insulinotropic Polypeptide Receptors Are Expressed in the Lateral Septum and Reduce Electrically-Evoked Dopamine Release as well as the Ability of Cocaine to Increase Extracellular Dopamine | ACS Chemical Neuroscience pubs.acs.org/doi/10.1021/...
Samsung Biologics to launch $1.8 billion all-cash bid for PolyPeptide reut.rs/4f9W64x
Samsung Biologics to launch $1.8 billion all-cash bid for PolyPeptide
South Korea's Samsung Biologics will launch a 1.46 billion Swiss francs ($1.81 billion) all-cash bid for Swiss contract drugmaker PolyPeptide , the companies said in separate statements.
reut.rs
July 20, 2026 at 12:20 AM
Samsung Biologics to launch $1.8 billion all-cash bid for PolyPeptide reut.rs/4f9W64x
☕ @kutaylab.bsky.social & co identify #lamin B receptor (LBR) and lamina-associated polypeptide 2 (LAP2) as major factors that tether #heterochromatin to the envelope. Deletion of these proteins causes changes in 3D #genome organization, gene expression and cell fate determination.
bit.ly/4aPkNBc
bit.ly/4aPkNBc
LBR and LAP2 mediate heterochromatin tethering to the nuclear periphery to preserve genome homeostasis - Nature Cell Biology
Lewis et al. identify lamin B receptor (LBR) and lamina-associated polypeptide 2 (LAP2) as major factors that tether heterochromatin to the envelope. Deletion of these proteins causes changes in 3D ge...
bit.ly
March 4, 2026 at 1:09 PM
☕ @kutaylab.bsky.social & co identify #lamin B receptor (LBR) and lamina-associated polypeptide 2 (LAP2) as major factors that tether #heterochromatin to the envelope. Deletion of these proteins causes changes in 3D #genome organization, gene expression and cell fate determination.
bit.ly/4aPkNBc
bit.ly/4aPkNBc
Modifying a pancreas to also produce desired sex hormones is just giving it one more thing to do, it already releases insulin and glucagon and somatostatin and pancreatic polypeptide, what's one more hormone
July 19, 2024 at 1:16 AM
Modifying a pancreas to also produce desired sex hormones is just giving it one more thing to do, it already releases insulin and glucagon and somatostatin and pancreatic polypeptide, what's one more hormone
Up front & free to read in our Jan issue #editorspicks: Molecular mechanisms underlying glucose‑dependent insulinotropic polypeptide secretion in human duodenal organoids tinyurl.com/muc8sata
Molecular mechanisms underlying glucose-dependent insulinotropic polypeptide secretion in human duodenal organoids - Diabetologia
Aims/hypothesis Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone secreted by enteroendocrine K cells in the proximal small intestine. This study aimed to explore the function ...
tinyurl.com
January 6, 2025 at 7:01 AM
Up front & free to read in our Jan issue #editorspicks: Molecular mechanisms underlying glucose‑dependent insulinotropic polypeptide secretion in human duodenal organoids tinyurl.com/muc8sata
Another GLP-1 drug success. Tirzepatide in heart failure with preserved ejection fraction (HFpEF) with longer term follow-up than 2 previous trials with semaglutide
nejm.org/doi/full/10....
in people with BMI >30; no data yet for HFpEF in people without obesity
nejm.org/doi/full/10....
in people with BMI >30; no data yet for HFpEF in people without obesity
Tirzepatide for Heart Failure with Preserved Ejection Fraction and Obesity | NEJM
Obesity increases the risk of heart failure with preserved ejection fraction. Tirzepatide, a long-acting agonist of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor...
nejm.org
November 16, 2024 at 3:12 PM
Another GLP-1 drug success. Tirzepatide in heart failure with preserved ejection fraction (HFpEF) with longer term follow-up than 2 previous trials with semaglutide
nejm.org/doi/full/10....
in people with BMI >30; no data yet for HFpEF in people without obesity
nejm.org/doi/full/10....
in people with BMI >30; no data yet for HFpEF in people without obesity
1/ We’re excited to announce our first speaker of London Calling 2025 Jeff Nivala will share their groundbreaking ‘proof-of-concept' method showcasing the capability of #nanopore sequencing to read #polypeptide strands.
Register here: nanoporetech.com/about/events... #nanoporeconf
Register here: nanoporetech.com/about/events... #nanoporeconf
January 13, 2025 at 4:35 PM
1/ We’re excited to announce our first speaker of London Calling 2025 Jeff Nivala will share their groundbreaking ‘proof-of-concept' method showcasing the capability of #nanopore sequencing to read #polypeptide strands.
Register here: nanoporetech.com/about/events... #nanoporeconf
Register here: nanoporetech.com/about/events... #nanoporeconf
does my 9 year old need a $70 "polypeptide firming moisturizer" pls respond
April 9, 2024 at 9:07 PM
does my 9 year old need a $70 "polypeptide firming moisturizer" pls respond