Sevoflurane #postconditioning alleviates cognitive impairment after hemorrhagic shock by activating the SIRT1/HIF-1α/NLRP3 pathway. doi.org/10.4103/mgr.... #Sevoflurane #CognitiveImpairment #HemorrhagicShock #Neuroprotection #SIRT1 #HIF1α #NLRP3 #MedicalResearch #Anesthesia #MedSky #neuroskyence
February 11, 2026 at 3:13 AM
Sevoflurane #postconditioning alleviates cognitive impairment after hemorrhagic shock by activating the SIRT1/HIF-1α/NLRP3 pathway. doi.org/10.4103/mgr.... #Sevoflurane #CognitiveImpairment #HemorrhagicShock #Neuroprotection #SIRT1 #HIF1α #NLRP3 #MedicalResearch #Anesthesia #MedSky #neuroskyence
Possible role of pannexin 1/P2x7 purinoceptor in neuroprotective mechanism of ischemic postconditioning in mice #MECFS #LongCovid #PANX1 #P2X7 #SARSCoV2
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Possible role of pannexin 1/P2x7 purinoceptor in neuroprotective mechanism of ischemic postconditioning in mice
Previous studies have suggested a significant role of pannexin 1 (Panx1)/P2X7 receptor complex in cardioprotective mechanism of ischemic preconditioni…
www.sciencedirect.com
February 2, 2025 at 6:28 PM
Possible role of pannexin 1/P2x7 purinoceptor in neuroprotective mechanism of ischemic postconditioning in mice #MECFS #LongCovid #PANX1 #P2X7 #SARSCoV2
www.sciencedirect.com/science/arti...
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Hu et al. show that sevoflurane postconditioning alleviates cognitive impairment after hemorrhagic shock and resuscitation by activating the SIRT1/HIF-1α/NLRP3 pathway. doi.org/10.4103/mgr.... #AnestheticGas #Sevoflurane #CognitiveImpairment #Neuroprotection #MedicalResearch #MedSky #neuroskyence
February 25, 2026 at 3:20 AM
Hu et al. show that sevoflurane postconditioning alleviates cognitive impairment after hemorrhagic shock and resuscitation by activating the SIRT1/HIF-1α/NLRP3 pathway. doi.org/10.4103/mgr.... #AnestheticGas #Sevoflurane #CognitiveImpairment #Neuroprotection #MedicalResearch #MedSky #neuroskyence
A paper using RRID:AB_228341 from @thermofishersci.bsky.social was just published in Medical Gas Research. Thanks for making your methods matter! #RRID #STMpublishing #reproducibility
Anesthetic gas sevoflurane postconditioning alleviates cognitive impairment induced by hemorrhagic shock and resuscitation
Read the full paper: Anesthetic gas sevoflurane postconditioning alleviates cognitive impairment induced by hemorrhagic shock and resuscitation
doi.org
February 28, 2026 at 8:02 AM
A paper using RRID:AB_228341 from @thermofishersci.bsky.social was just published in Medical Gas Research. Thanks for making your methods matter! #RRID #STMpublishing #reproducibility
Long-term efficacy of remote ischaemic postconditioning after rt-PA intravenous thrombolysis in patients with acute ischaemic stroke
STRENGTHS AND LIMITATIONS OF THIS STUDY This long-term follow-up of a randomised controlled trial with blinded outcome assessment helps fill the evidence gap…
STRENGTHS AND LIMITATIONS OF THIS STUDY This long-term follow-up of a randomised controlled trial with blinded outcome assessment helps fill the evidence gap…
Long-term efficacy of remote ischaemic postconditioning after rt-PA intravenous thrombolysis in patients with acute ischaemic stroke
STRENGTHS AND LIMITATIONS OF THIS STUDY This long-term follow-up of a randomised controlled trial with blinded outcome assessment helps fill the evidence gap regarding the sustained efficacy of remote ischaemic postconditioning. Propensity score analysis using inverse probability of treatment weighting was employed to adjust for baseline confounding, enhancing the reliability of findings on functional outcomes and stroke/transient ischaemic attack recurrence.
animeaura.store
October 30, 2025 at 12:48 AM
Long-term efficacy of remote ischaemic postconditioning after rt-PA intravenous thrombolysis in patients with acute ischaemic stroke
STRENGTHS AND LIMITATIONS OF THIS STUDY This long-term follow-up of a randomised controlled trial with blinded outcome assessment helps fill the evidence gap…
STRENGTHS AND LIMITATIONS OF THIS STUDY This long-term follow-up of a randomised controlled trial with blinded outcome assessment helps fill the evidence gap…
The Cardioprotective Effect of Ischemic Postconditioning is Mediated by Inhibiting RAP2C-MAP4K4 Pathway https://www.biorxiv.org/content/10.1101/2024.12.04.626922v1
The Cardioprotective Effect of Ischemic Postconditioning is Mediated by Inhibiting RAP2C-MAP4K4 Pathway https://www.biorxiv.org/content/10.1101/2024.12.04.626922v1
Objective:Ischemic postconditioning (PostC) serves as a vital defense for cardiomyocytes against the
www.biorxiv.org
December 5, 2024 at 1:31 PM
The Cardioprotective Effect of Ischemic Postconditioning is Mediated by Inhibiting RAP2C-MAP4K4 Pathway https://www.biorxiv.org/content/10.1101/2024.12.04.626922v1
Endovascular Treatment Combined with Remote Ischemic Postconditioning in Patients with Acute Ischemic Stroke Improves the Prognosis,a Multicenter, Randomized, Prospective Trial(EnTRIPS): study protocol for a randomized clinical trial https://www.medrxiv.org/content/10.1101/2025.03.20.25324340v1
March 22, 2025 at 12:26 AM
Endovascular Treatment Combined with Remote Ischemic Postconditioning in Patients with Acute Ischemic Stroke Improves the Prognosis,a Multicenter, Randomized, Prospective Trial(EnTRIPS): study protocol for a randomized clinical trial https://www.medrxiv.org/content/10.1101/2025.03.20.25324340v1
📃Scientific paper: Determination of significant parameters in remote ischemic postconditioning for ischemic stroke in e...
➡️ Continued on ES/IODE
➡️ Continued on ES/IODE
July 20, 2024 at 10:16 PM
📃Scientific paper: Determination of significant parameters in remote ischemic postconditioning for ischemic stroke in e...
➡️ Continued on ES/IODE
➡️ Continued on ES/IODE
A study on STEMI/NSTEMI patients shows that treatment with trimetazidine and levocarnitine reduced myocardial fibrosis, increased ejection fraction, and enhanced myocardial reserve. Pharmacological postconditioning proves effective and safe, with no serious complications observed
December 12, 2024 at 8:38 AM
A study on STEMI/NSTEMI patients shows that treatment with trimetazidine and levocarnitine reduced myocardial fibrosis, increased ejection fraction, and enhanced myocardial reserve. Pharmacological postconditioning proves effective and safe, with no serious complications observed
www.sciencedirect.com/science/arti...
"Therefore, activation of Panx1/P2X7 purinoceptors appears to play a significant role in the neuroprotective mechanism of IPC."
"Therefore, activation of Panx1/P2X7 purinoceptors appears to play a significant role in the neuroprotective mechanism of IPC."
Possible role of pannexin 1/P2x7 purinoceptor in neuroprotective mechanism of ischemic postconditioning in mice
Previous studies have suggested a significant role of pannexin 1 (Panx1)/P2X7 receptor complex in cardioprotective mechanism of ischemic preconditioni…
www.sciencedirect.com
February 2, 2025 at 6:28 PM
www.sciencedirect.com/science/arti...
"Therefore, activation of Panx1/P2X7 purinoceptors appears to play a significant role in the neuroprotective mechanism of IPC."
"Therefore, activation of Panx1/P2X7 purinoceptors appears to play a significant role in the neuroprotective mechanism of IPC."
www.sciencedirect.com/science/arti...
"IPC-induced neuroprotective effects were significantly abolished by pretreatment of mefloquine (15.0 mg/kg orally; 30.0 mg/kg orally), blocker of Panx1/P2X7 purinoceptor."
"IPC-induced neuroprotective effects were significantly abolished by pretreatment of mefloquine (15.0 mg/kg orally; 30.0 mg/kg orally), blocker of Panx1/P2X7 purinoceptor."
Possible role of pannexin 1/P2x7 purinoceptor in neuroprotective mechanism of ischemic postconditioning in mice
Previous studies have suggested a significant role of pannexin 1 (Panx1)/P2X7 receptor complex in cardioprotective mechanism of ischemic preconditioni…
www.sciencedirect.com
February 2, 2025 at 6:28 PM
www.sciencedirect.com/science/arti...
"IPC-induced neuroprotective effects were significantly abolished by pretreatment of mefloquine (15.0 mg/kg orally; 30.0 mg/kg orally), blocker of Panx1/P2X7 purinoceptor."
"IPC-induced neuroprotective effects were significantly abolished by pretreatment of mefloquine (15.0 mg/kg orally; 30.0 mg/kg orally), blocker of Panx1/P2X7 purinoceptor."
The Cardioprotective Effect of Ischemic Postconditioning is Mediated by Inhibiting RAP2C-MAP4K4 Pathway https://www.biorxiv.org/content/10.1101/2024.12.04.626922v1
The Cardioprotective Effect of Ischemic Postconditioning is Mediated by Inhibiting RAP2C-MAP4K4 Pathway https://www.biorxiv.org/content/10.1101/2024.12.04.626922v1
Objective:Ischemic postconditioning (PostC) serves as a vital defense for cardiomyocytes against the
www.biorxiv.org
December 5, 2024 at 1:31 PM
The Cardioprotective Effect of Ischemic Postconditioning is Mediated by Inhibiting RAP2C-MAP4K4 Pathway https://www.biorxiv.org/content/10.1101/2024.12.04.626922v1
【脳梗塞EVT成功後の局所虚血プレコンで梗塞巣増大抑制：小規模RCT/Stroke】Jul.16
中国単施設、脳梗塞への血栓回収に成功した60例をランダム化——
・（元）閉塞部「2分バルーン拡張⇨2分再疎通」×4サイクルで対照
に比べ、48時間後の梗塞巣増大を有意に抑制。
・一方、90日後mRSには群間差なし。
抄録🔗 x.gd/RHKPx
中国単施設、脳梗塞への血栓回収に成功した60例をランダム化——
・（元）閉塞部「2分バルーン拡張⇨2分再疎通」×4サイクルで対照
に比べ、48時間後の梗塞巣増大を有意に抑制。
・一方、90日後mRSには群間差なし。
抄録🔗 x.gd/RHKPx
Ischemic Postconditioning in Patients With Acute Stroke With Successful Recanalization After Endovascular Therapy: A Pilot Randomized Controlled Trial | Stroke
BACKGROUND: Ischemia-reperfusion injury contributes to continued infarct growth despite successful
recanalization. Ischemic postconditioning (IPostC) reduces infarct size in preclinical
models, but it...
x.gd
July 18, 2026 at 2:15 AM
【脳梗塞EVT成功後の局所虚血プレコンで梗塞巣増大抑制：小規模RCT/Stroke】Jul.16
中国単施設、脳梗塞への血栓回収に成功した60例をランダム化——
・（元）閉塞部「2分バルーン拡張⇨2分再疎通」×4サイクルで対照
に比べ、48時間後の梗塞巣増大を有意に抑制。
・一方、90日後mRSには群間差なし。
抄録🔗 x.gd/RHKPx
中国単施設、脳梗塞への血栓回収に成功した60例をランダム化——
・（元）閉塞部「2分バルーン拡張⇨2分再疎通」×4サイクルで対照
に比べ、48時間後の梗塞巣増大を有意に抑制。
・一方、90日後mRSには群間差なし。
抄録🔗 x.gd/RHKPx