In this @biorxivpreprint.bsky.social @biorxiv-immuno.bsky.social, we show that #oral #bacteria can break down #food #allergens, potentially affecting their systemic absorption, #IgE recognition, and allergic reactions—including #anaphylaxis.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
March 25, 2025 at 9:27 AM
Tomorrow, in #preprinthub2 @alisaiakupova.bsky.social will present a preprint from Xuyu Zhou’s lab on how #TCR signal strength determines #Treg instability and discrimination of self versus non-self antigens 🐁 ⏳🌪️ #immunosky
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org
February 23, 2026 at 7:04 PM
Tomorrow, in #preprinthub2 @alisaiakupova.bsky.social will present a preprint from Xuyu Zhou’s lab on how #TCR signal strength determines #Treg instability and discrimination of self versus non-self antigens 🐁 ⏳🌪️ #immunosky
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
first #preprinthub2 review in @natrevimmunol.bsky.social ⚡️
Not one but two new Journal Club articles from @preprintclub.bsky.social discussing recent @biorxiv-immuno.bsky.social preprints on iron and zinc homeostasis in #macrophages.
#immunosky
#immunosky
April 23, 2025 at 3:51 PM
first #preprinthub2 review in @natrevimmunol.bsky.social ⚡️
@cleeterichter.bsky.social will present this preprint today in #preprinthub2! ⚡️🚦🐁 #immunosky @ucsdhealthsci.bsky.social
This week on preprint hub #1, Chester Chang from MD Anderson Cancer Center will present a preprint from Dr. Ananda Goldrath's lab about how proteostasis sustains T-cell differentiation potential and tumour-infiltrating lymphocyte function
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org
March 31, 2026 at 8:39 AM
@cleeterichter.bsky.social will present this preprint today in #preprinthub2! ⚡️🚦🐁 #immunosky @ucsdhealthsci.bsky.social
Stay tuned, we will resume our Preprint Club sessions in October at #preprinthub2! If you are in Vienna, Berlin or Charlottesville, you can reach out to join the initiative by expressing your interest at preprintclub.hub2[at]gmail.com 📗
September 27, 2026 at 8:02 AM
Stay tuned, we will resume our Preprint Club sessions in October at #preprinthub2! If you are in Vienna, Berlin or Charlottesville, you can reach out to join the initiative by expressing your interest at preprintclub.hub2[at]gmail.com 📗
Today Teresa from #CeMM #preprinthub2 will lead a discussion of a #preprint from Padera lab on how lymph nodes link sex-biased immune #aging to compromised antigen recognition @harvardmed.bsky.social 👵👴+🧪
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
March 11, 2025 at 8:57 AM
Today Teresa from #CeMM #preprinthub2 will lead a discussion of a #preprint from Padera lab on how lymph nodes link sex-biased immune #aging to compromised antigen recognition @harvardmed.bsky.social 👵👴+🧪
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Today, in #preprinthub2 Amitava Sinha will present a #preprint from Angelo lab @stanfordmedicine.bsky.social on how the immunometabolic topography of TB granulomas governs cellular organization and bacterial control. 🦠🚦🙊 #immunosky
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
June 24, 2025 at 12:34 PM
Today, in #preprinthub2 Amitava Sinha will present a #preprint from Angelo lab @stanfordmedicine.bsky.social on how the immunometabolic topography of TB granulomas governs cellular organization and bacterial control. 🦠🚦🙊 #immunosky
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Today, in #preprinthub2 Chloe and Meredith @uvaimmunology.bsky.social will present a #preprint from the Martin Vaeth lab @uni-wuerzburg.de on how the glucose transporter GLUT3 controls #Treg function 🍬🚡🕹️ #immunosky
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org
April 21, 2026 at 7:19 AM
Today, in #preprinthub2 Chloe and Meredith @uvaimmunology.bsky.social will present a #preprint from the Martin Vaeth lab @uni-wuerzburg.de on how the glucose transporter GLUT3 controls #Treg function 🍬🚡🕹️ #immunosky
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Today, in #preprinthub2 @cleeterichter.bsky.social will lead a discussion of a #preprint from @santoshvardhana.bsky.social @mskcancercenter.bsky.social on MEK-dependent bioenergetic demand driving terminal CD8+ T cell exhaustion. 🍰💥 #immunosky
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
June 10, 2025 at 12:25 PM
Today, in #preprinthub2 @cleeterichter.bsky.social will lead a discussion of a #preprint from @santoshvardhana.bsky.social @mskcancercenter.bsky.social on MEK-dependent bioenergetic demand driving terminal CD8+ T cell exhaustion. 🍰💥 #immunosky
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Today, in #preprinthub2 @mnaumova.bsky.social will present a #preprint on spatio-temporal mapping of #immune cell dynamics during human sequential lymph node metastasis from Pengfei Qiu lab (Shandong Cancer Hospital) 🧑🤝🧑🧩💻 #medsky #immunosky
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org
April 14, 2026 at 8:41 AM
Today, in #preprinthub2 @mnaumova.bsky.social will present a #preprint on spatio-temporal mapping of #immune cell dynamics during human sequential lymph node metastasis from Pengfei Qiu lab (Shandong Cancer Hospital) 🧑🤝🧑🧩💻 #medsky #immunosky
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
We continue this endeavor with two hubs: #preprinthub1 scientists are based in @ox.ac.uk @sinaiimmuno.bsky.social @mdanderson.bsky.social @karolinskainst.bsky.social & University of Toronto; #preprinthub2 at Medical University of Vienna, @mdc-berlin.bsky.social, Charité and Ragon Institute. 🫡
December 10, 2024 at 1:51 PM
We continue this endeavor with two hubs: #preprinthub1 scientists are based in @ox.ac.uk @sinaiimmuno.bsky.social @mdanderson.bsky.social @karolinskainst.bsky.social & University of Toronto; #preprinthub2 at Medical University of Vienna, @mdc-berlin.bsky.social, Charité and Ragon Institute. 🫡
Today Lisa @cemm.oeaw.ac.at #preprinthub2 will discuss a #preprint about cytokine-bearing bacterial outer membrane vesicles with empowered efficacy in intratumoral #immunotherapy 🦠🧫🐭 #immunosky #OMVs
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org
May 12, 2026 at 7:08 AM
Today Lisa @cemm.oeaw.ac.at #preprinthub2 will discuss a #preprint about cytokine-bearing bacterial outer membrane vesicles with empowered efficacy in intratumoral #immunotherapy 🦠🧫🐭 #immunosky #OMVs
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Today in #preprinthub2 Kelsey Voss + @cleeterichter.bsky.social will present a #preprint from @elmiguelche.bsky.social @gimmfoundation.bsky.social
on how monocytes control organismal energy homeostasis 🕹️🧍♀️🌊
www.biorxiv.org/content/10.1...
on how monocytes control organismal energy homeostasis 🕹️🧍♀️🌊
www.biorxiv.org/content/10.1...
Monocyte control of organismal energy homeostasis
Multicellular organisms rely on inter-organ communication networks to maintain vital parameters within a dynamic physiological range. Macrophages are central to this homeostatic control system, sensin...
www.biorxiv.org
March 18, 2025 at 8:26 AM
Today in #preprinthub2 Kelsey Voss + @cleeterichter.bsky.social will present a #preprint from @elmiguelche.bsky.social @gimmfoundation.bsky.social
on how monocytes control organismal energy homeostasis 🕹️🧍♀️🌊
www.biorxiv.org/content/10.1...
on how monocytes control organismal energy homeostasis 🕹️🧍♀️🌊
www.biorxiv.org/content/10.1...
Today in #preprinthub2 @alisaiakupova.bsky.social will discuss a #preprint from @krishnaroskin.bsky.social @cincyresearch.bsky.social on how B cell repertoire of children with AD exhibits altered #IgE maturation associated with allergic food sensitization. 🥜🐕👶
#medsky
www.biorxiv.org/content/10.1...
#medsky
www.biorxiv.org/content/10.1...
B cell repertoire of children with atopic dermatitis exhibit altered IgE maturation associated with allergic food sensitization
IgE B cells produce antibodies responsible for the inappropriate specificity seen in allergic disease. In this study, we sequence antibody gene repertoires from a large, well-characterized early life ...
www.biorxiv.org
May 6, 2025 at 12:57 PM
Today in #preprinthub2 @alisaiakupova.bsky.social will discuss a #preprint from @krishnaroskin.bsky.social @cincyresearch.bsky.social on how B cell repertoire of children with AD exhibits altered #IgE maturation associated with allergic food sensitization. 🥜🐕👶
#medsky
www.biorxiv.org/content/10.1...
#medsky
www.biorxiv.org/content/10.1...
Tomorrow at #PreprintHub2, Raisa Brito from @mdc-berlin.bsky.social will present a #preprint by Prof. Dr. Karsten Kretschmer titled “Functional Dichotomy of Developmental Foxp3+ Treg Cell Subsets in the Visceral Adipose Tissue of Lean and Obese Mice”
October 20, 2025 at 7:02 PM
Tomorrow at #PreprintHub2, Raisa Brito from @mdc-berlin.bsky.social will present a #preprint by Prof. Dr. Karsten Kretschmer titled “Functional Dichotomy of Developmental Foxp3+ Treg Cell Subsets in the Visceral Adipose Tissue of Lean and Obese Mice”
Today #preprinthub2 Tamina and Joel will present a #preprint from @miriammerad.bsky.social @samhegde.bsky.social @sinaiimmuno.bsky.social on how myeloid progenitor dysregulation fuels immunosuppressive #macrophages in tumors ✍️💥
🥸👇
www.biorxiv.org/content/10.1...
🥸👇
www.biorxiv.org/content/10.1...
Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumors
Monocyte–derived macrophages (mo-macs) drive immunosuppression in the tumor microenvironment (TME) and tumor-enhanced myelopoiesis in the bone marrow (BM) fuels these populations. Here, we performed p...
www.biorxiv.org
December 17, 2024 at 1:32 PM
Today #preprinthub2 Tamina and Joel will present a #preprint from @miriammerad.bsky.social @samhegde.bsky.social @sinaiimmuno.bsky.social on how myeloid progenitor dysregulation fuels immunosuppressive #macrophages in tumors ✍️💥
🥸👇
www.biorxiv.org/content/10.1...
🥸👇
www.biorxiv.org/content/10.1...
Today in #preprinthub2 Julia Eder @cemm.oeaw.ac.at will present a #preprint on how #singlecell immunophenotyping identifies CD8+ GZMK+ IFNG+ T cells as a key immune population in cutaneous Lyme disease 👋👾🩸
www.biorxiv.org/content/10.1...
#immunosky #medsky
www.biorxiv.org/content/10.1...
#immunosky #medsky
www.biorxiv.org
February 17, 2026 at 8:29 AM
Today in #preprinthub2 Julia Eder @cemm.oeaw.ac.at will present a #preprint on how #singlecell immunophenotyping identifies CD8+ GZMK+ IFNG+ T cells as a key immune population in cutaneous Lyme disease 👋👾🩸
www.biorxiv.org/content/10.1...
#immunosky #medsky
www.biorxiv.org/content/10.1...
#immunosky #medsky
Today, in #preprinthub2 @alisaiakupova.bsky.social @mdc-berlin.bsky.social will present a #preprint from Katya Koltsova lab (Cedars-Sinai Medical Center) on how IL-17RC signaling connects intestinal #microbiota and #neuroimmune interactions in #atherosclerosis 🍔🦠🐭
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org
April 7, 2026 at 8:35 AM
Today, in #preprinthub2 @alisaiakupova.bsky.social @mdc-berlin.bsky.social will present a #preprint from Katya Koltsova lab (Cedars-Sinai Medical Center) on how IL-17RC signaling connects intestinal #microbiota and #neuroimmune interactions in #atherosclerosis 🍔🦠🐭
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Tomorrow in #PreprintHub2,
@alisaiakupova.bsky.social from
@mdc-berlin.bsky.social will present a #preprint on tolerance to dietary antigens from the Xiaohuan Guo lab 🧬📷
Preprint: www.researchsquare.com/article/rs-4...
@alisaiakupova.bsky.social from
@mdc-berlin.bsky.social will present a #preprint on tolerance to dietary antigens from the Xiaohuan Guo lab 🧬📷
Preprint: www.researchsquare.com/article/rs-4...
RORγt+ APCs require a distinct cis-regulatory element to instruct tolerance to dietary antigens
Oral tolerance represents a hallmark of intestinal mucosal immunity to prevent inflammatory responses to harmless natural antigens, such as dietary components or commensal organisms. However, the unde...
www.researchsquare.com
September 22, 2025 at 8:29 PM
Tomorrow in #PreprintHub2,
@alisaiakupova.bsky.social from
@mdc-berlin.bsky.social will present a #preprint on tolerance to dietary antigens from the Xiaohuan Guo lab 🧬📷
Preprint: www.researchsquare.com/article/rs-4...
@alisaiakupova.bsky.social from
@mdc-berlin.bsky.social will present a #preprint on tolerance to dietary antigens from the Xiaohuan Guo lab 🧬📷
Preprint: www.researchsquare.com/article/rs-4...
Tomorrow in #preprinthub2, @tomikostevc.bsky.social
@bihatcharite.bsky.social will present a #preprint from
@sciencekyle.bsky.social lab about how programmable synthetic #cytokine receptors polarize #macrophages to user-defined functional states 🎮🗺️👾 #immunosky
www.biorxiv.org/content/10.6...
@bihatcharite.bsky.social will present a #preprint from
@sciencekyle.bsky.social lab about how programmable synthetic #cytokine receptors polarize #macrophages to user-defined functional states 🎮🗺️👾 #immunosky
www.biorxiv.org/content/10.6...
Programmable synthetic cytokine receptors polarize macrophages to user-defined functional states
Technology that precisely controls macrophage polarization to distinct functional states would deepen our understanding of macrophage biology and enable the development of new macrophage cell therapie...
www.biorxiv.org
June 15, 2026 at 5:53 PM
Tomorrow in #preprinthub2, @tomikostevc.bsky.social
@bihatcharite.bsky.social will present a #preprint from
@sciencekyle.bsky.social lab about how programmable synthetic #cytokine receptors polarize #macrophages to user-defined functional states 🎮🗺️👾 #immunosky
www.biorxiv.org/content/10.6...
@bihatcharite.bsky.social will present a #preprint from
@sciencekyle.bsky.social lab about how programmable synthetic #cytokine receptors polarize #macrophages to user-defined functional states 🎮🗺️👾 #immunosky
www.biorxiv.org/content/10.6...
Today at #PreprintHub2, Elisa Sánchez from Universidad Autónoma de Madrid will present the preprint by @alexaweingarden.bsky.social, “Gut microbial composition modulates food-specific CD4+ T cells in food allergy” from the Marc K. Jenkins lab 🥜🤒❌
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
February 3, 2026 at 11:34 AM
Today at #PreprintHub2, Elisa Sánchez from Universidad Autónoma de Madrid will present the preprint by @alexaweingarden.bsky.social, “Gut microbial composition modulates food-specific CD4+ T cells in food allergy” from the Marc K. Jenkins lab 🥜🤒❌
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Today, in #preprinthub2 Michelle @uvaimmunology.bsky.social will present a #preprint from Maria José Sá and
Carles Ubeda labs on how gut #microbiome changes over the course of multiple sclerosis differentially influence #autoimmune #neuroinflammation 🥦🧩🦠 #immunosky
www.biorxiv.org/content/10.6...
Carles Ubeda labs on how gut #microbiome changes over the course of multiple sclerosis differentially influence #autoimmune #neuroinflammation 🥦🧩🦠 #immunosky
www.biorxiv.org/content/10.6...
www.biorxiv.org
April 28, 2026 at 7:59 AM
Today, in #preprinthub2 Michelle @uvaimmunology.bsky.social will present a #preprint from Maria José Sá and
Carles Ubeda labs on how gut #microbiome changes over the course of multiple sclerosis differentially influence #autoimmune #neuroinflammation 🥦🧩🦠 #immunosky
www.biorxiv.org/content/10.6...
Carles Ubeda labs on how gut #microbiome changes over the course of multiple sclerosis differentially influence #autoimmune #neuroinflammation 🥦🧩🦠 #immunosky
www.biorxiv.org/content/10.6...
Today at #PreprintHub2, Teresa Neuwirth from
@cemm.oeaw.ac.at will present a #preprint by
@retickerflynn.bsky.social on how Type I interferon signaling drives divergent metastatic phenotypes and immunotherapy responses 🧬🔬
www.biorxiv.org/content/10.1...
@cemm.oeaw.ac.at will present a #preprint by
@retickerflynn.bsky.social on how Type I interferon signaling drives divergent metastatic phenotypes and immunotherapy responses 🧬🔬
www.biorxiv.org/content/10.1...
Type I interferon signaling instills divergent metastatic phenotypes and immunotherapy responses
Metastatic colonization of distant tissues is responsible for most cancer deaths, yet while this colonization is typically preceded by lymph node (LN) metastasis, the clonal and functional relationshi...
www.biorxiv.org
October 7, 2025 at 11:55 AM
Today at #PreprintHub2, Teresa Neuwirth from
@cemm.oeaw.ac.at will present a #preprint by
@retickerflynn.bsky.social on how Type I interferon signaling drives divergent metastatic phenotypes and immunotherapy responses 🧬🔬
www.biorxiv.org/content/10.1...
@cemm.oeaw.ac.at will present a #preprint by
@retickerflynn.bsky.social on how Type I interferon signaling drives divergent metastatic phenotypes and immunotherapy responses 🧬🔬
www.biorxiv.org/content/10.1...
Today, in #preprinthub2 Marie-Therese from @uoe-igc.bsky.social will discuss a #preprint from Susana Gonzalo and Lilian N.D. Silva on how STING causes replication stress and nascent DNA degradation via SAMHD1 🧬🔥👵 #aging #immunosky
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
www.biorxiv.org
May 5, 2026 at 7:34 AM
Today, in #preprinthub2 Marie-Therese from @uoe-igc.bsky.social will discuss a #preprint from Susana Gonzalo and Lilian N.D. Silva on how STING causes replication stress and nascent DNA degradation via SAMHD1 🧬🔥👵 #aging #immunosky
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Today CeMM’s Daniel and Sophie in #preprinthub2 will present a #preprint from @umcgroningen.bsky.social @darshakbhatt.com
on how programming #alphavirus with IFN-g overrides the adverse effects of #macrophages on oncolytic virotherapy 🦠🔋💊
www.biorxiv.org/content/10.1...
on how programming #alphavirus with IFN-g overrides the adverse effects of #macrophages on oncolytic virotherapy 🦠🔋💊
www.biorxiv.org/content/10.1...
www.biorxiv.org
February 25, 2025 at 9:53 AM
Today CeMM’s Daniel and Sophie in #preprinthub2 will present a #preprint from @umcgroningen.bsky.social @darshakbhatt.com
on how programming #alphavirus with IFN-g overrides the adverse effects of #macrophages on oncolytic virotherapy 🦠🔋💊
www.biorxiv.org/content/10.1...
on how programming #alphavirus with IFN-g overrides the adverse effects of #macrophages on oncolytic virotherapy 🦠🔋💊
www.biorxiv.org/content/10.1...