Functional phenotyping of genomic variants using joint multiomic single-cell DNA–RNA sequencing. #GenomicVariants #SingleCell #scDNAseq #scRNAseq @natmethods.nature.com 🧬 🖥️
www.nature.com/articles/s41...
www.nature.com/articles/s41...
September 4, 2025 at 8:31 AM
Functional phenotyping of genomic variants using joint multiomic single-cell DNA–RNA sequencing. #GenomicVariants #SingleCell #scDNAseq #scRNAseq @natmethods.nature.com 🧬 🖥️
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Faster growing tumours do worse. This extraordinary study dissects growth rate dynamics *within* tumours with scDNAseq data. Congrats to Oliva and team. https://buff.ly/4iaTmTP Found with researchbriefing.com
Characterizing the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER - Nature Genetics
Single-cell Proliferation Rate Inference in Non-homogeneous Tumors through Evolutionary Routes (SPRINTER) allows users to infer proliferation rates of individual clones within a tumor from…
buff.ly
December 3, 2024 at 9:00 AM
Faster growing tumours do worse. This extraordinary study dissects growth rate dynamics *within* tumours with scDNAseq data. Congrats to Oliva and team. https://buff.ly/4iaTmTP Found with researchbriefing.com
A resource and computational approach for quantifying gene editing allelism at single-cell resolution [new]
GUMM: scDNAseq atlas infers sc gene edit allelism from CRISPR-Cas9.
GUMM: scDNAseq atlas infers sc gene edit allelism from CRISPR-Cas9.
May 27, 2025 at 5:00 PM
A resource and computational approach for quantifying gene editing allelism at single-cell resolution [new]
GUMM: scDNAseq atlas infers sc gene edit allelism from CRISPR-Cas9.
GUMM: scDNAseq atlas infers sc gene edit allelism from CRISPR-Cas9.
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More than 5 years ago we embarked on the journey of using #scDNAseq to study genetic heterogeneity in #Leishmania.
www.nature.com/articles/s41...
More than 5 years ago we embarked on the journey of using #scDNAseq to study genetic heterogeneity in #Leishmania.
www.nature.com/articles/s41...
Evaluation of whole genome amplification and bioinformatic methods for the characterization of Leishmania genomes at a single cell level - Scientific Reports
Scientific Reports - Evaluation of whole genome amplification and bioinformatic methods for the characterization of Leishmania genomes at a single cell level
www.nature.com
September 11, 2025 at 10:15 AM
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More than 5 years ago we embarked on the journey of using #scDNAseq to study genetic heterogeneity in #Leishmania.
www.nature.com/articles/s41...
More than 5 years ago we embarked on the journey of using #scDNAseq to study genetic heterogeneity in #Leishmania.
www.nature.com/articles/s41...
Single Nucleotide Polymorphism (SNP) and Antibody-based Cell Sorting (SNACS): A tool for demultiplexing single-cell DNA sequencing data https://www.biorxiv.org/content/10.1101/2024.02.07.579345v1
Single Nucleotide Polymorphism (SNP) and Antibody-based Cell Sorting (SNACS): A tool for demultiplexing single-cell DNA sequencing data https://www.biorxiv.org/content/10.1101/2024.02.07.579345v1
Motivation Recently, single cell DNA sequencing (scDNAseq) and multimodal profiling with the additio
www.biorxiv.org
February 11, 2024 at 6:53 AM
Single Nucleotide Polymorphism (SNP) and Antibody-based Cell Sorting (SNACS): A tool for demultiplexing single-cell DNA sequencing data https://www.biorxiv.org/content/10.1101/2024.02.07.579345v1
scLongTree: an accurate computational tool to infer the longitudinal tree for scDNAseq data https://www.biorxiv.org/content/10.1101/2023.11.11.566680v1
scLongTree: an accurate computational tool to infer the longitudinal tree for scDNAseq data https://www.biorxiv.org/content/10.1101/2023.11.11.566680v1
A subclonal tree that depicts the evolution of cancer cells is of interest in understanding how canc
www.biorxiv.org
November 15, 2023 at 6:52 PM
scLongTree: an accurate computational tool to infer the longitudinal tree for scDNAseq data https://www.biorxiv.org/content/10.1101/2023.11.11.566680v1
A comprehensive view of somatic mosaicism by single-cell DNA analysis. #SingleCell #scDNAseq #SomaticMosaicism @biorxivpreprint.bsky.social 🧪🧬 🖥️
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 8, 2025 at 3:25 PM
A comprehensive view of somatic mosaicism by single-cell DNA analysis. #SingleCell #scDNAseq #SomaticMosaicism @biorxivpreprint.bsky.social 🧪🧬 🖥️
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
DelSIEVE: cell phylogeny modeling of single nucleotide variants and deletions from single-cell DNA sequencing data. #scDNAseq #CellPhylogeny #SNV #Indels #GenomeBiology
genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com/articles/10....
September 1, 2025 at 3:01 PM
DelSIEVE: cell phylogeny modeling of single nucleotide variants and deletions from single-cell DNA sequencing data. #scDNAseq #CellPhylogeny #SNV #Indels #GenomeBiology
genomebiology.biomedcentral.com/articles/10....
genomebiology.biomedcentral.com/articles/10....
Single Nucleotide Polymorphism (SNP) and Antibody-based Cell Sorting (SNACS): A tool for demultiplexing single-cell DNA sequencing data https://www.biorxiv.org/content/10.1101/2024.02.07.579345v1
Single Nucleotide Polymorphism (SNP) and Antibody-based Cell Sorting (SNACS): A tool for demultiplexing single-cell DNA sequencing data https://www.biorxiv.org/content/10.1101/2024.02.07.579345v1
Motivation Recently, single cell DNA sequencing (scDNAseq) and multimodal profiling with the additio
www.biorxiv.org
February 11, 2024 at 6:53 AM
Single Nucleotide Polymorphism (SNP) and Antibody-based Cell Sorting (SNACS): A tool for demultiplexing single-cell DNA sequencing data https://www.biorxiv.org/content/10.1101/2024.02.07.579345v1
scLongTree: an accurate computational tool to infer the longitudinal tree for scDNAseq data https://www.biorxiv.org/content/10.1101/2023.11.11.566680v1
scLongTree: an accurate computational tool to infer the longitudinal tree for scDNAseq data https://www.biorxiv.org/content/10.1101/2023.11.11.566680v1
A subclonal tree that depicts the evolution of cancer cells is of interest in understanding how canc
www.biorxiv.org
November 15, 2023 at 6:52 PM
scLongTree: an accurate computational tool to infer the longitudinal tree for scDNAseq data https://www.biorxiv.org/content/10.1101/2023.11.11.566680v1
scLongTree: an accurate computational tool to infer the longitudinal tree for scDNAseq data [updated]
...to depict cancer cell evolution, understand growth, and inform prognosis & treatment.
...to depict cancer cell evolution, understand growth, and inform prognosis & treatment.
April 11, 2026 at 10:58 AM
scLongTree: an accurate computational tool to infer the longitudinal tree for scDNAseq data [updated]
...to depict cancer cell evolution, understand growth, and inform prognosis & treatment.
...to depict cancer cell evolution, understand growth, and inform prognosis & treatment.