KAT2A-mediated #succinylation of the #splicingfactor SRSF11 at K419 enhances #DNARepair and #radioresistance in #HCC by promoting RAD52 exon inclusion, linking #AlternativeSplicing to #GenomicStability and offering a potential therapeutic target.
#STTT: doi.org/10.1038/s413...
#STTT: doi.org/10.1038/s413...
November 12, 2025 at 11:35 AM
KAT2A-mediated #succinylation of the #splicingfactor SRSF11 at K419 enhances #DNARepair and #radioresistance in #HCC by promoting RAD52 exon inclusion, linking #AlternativeSplicing to #GenomicStability and offering a potential therapeutic target.
#STTT: doi.org/10.1038/s413...
#STTT: doi.org/10.1038/s413...